brain network - thalamocortical motif
DESCRIPTION
Speaker: Jimmy Lu Topics: Brain Network - Thalamocortical Motif Date: 2010.03.20 WECO Lab, CSIE, FJUTRANSCRIPT
Brain NetworksThalamocortical Motif
Speaker : Jimmy LuAdvisor : Hsing Mei
Web Computing Laboratory(WECO Lab)Computer Science and Information Engineering Department
Fu Jen Catholic University
04/12/2023 2WECO Lab, CSIE dept., FJU http://www.weco.net
Outline
Report proposal Background and review Small-world network Scale-free network Reentrant mapping Links, issues, and opinions Future work
04/12/2023 3WECO Lab, CSIE dept., FJU http://www.weco.net
Report Proposal
Thalamocortical motif Polysynatic loop structure Diffuse ascending projection Cognitive science Social networks Collective intelligence Web intelligence
04/12/2023 WECO Lab, CSIE dept., FJU http://www.weco.net
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Background and Review(1/3)
Thalamus process sensory
information as well as relaying it
As a gateway, a switch, or a relay
Reticular nucleus, intralaminar nuclei
04/12/2023 WECO Lab, CSIE dept., FJU http://www.weco.net
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Background and Review(2/3)
Cerebral cortex Brain map Plays a key role
in memory, attention, perceptual awareness, thought, language, and consciousness
Small-world, Scale-free
04/12/2023 WECO Lab, CSIE dept., FJU http://www.weco.net
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Background and Review(3/3)
Reentrant mapping Sensory information
go through the spine cord to the thalamus, and then relay it to the cortical areas
Dynamic core
Thalamocortical radiations
04/12/2023 7WECO Lab, CSIE dept., FJU http://www.weco.net
Small-world network(1/7)
The intermediate region between regular and random
04/12/2023 8WECO Lab, CSIE dept., FJU http://www.weco.net
Small-world network(2/7)
Clustering coefficient and path length
04/12/2023 9WECO Lab, CSIE dept., FJU http://www.weco.net
Small-world network(3/7)
Three examples Film actors Power grid C. elegans
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Small-world network(4/7)
The time to global infection is nearly as short as for a random graph
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Small-world network(5/7)
Small-world in the brain: micro view
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Small-world network(6/7)
Small-world in the brain: macro view
04/12/2023 13WECO Lab, CSIE dept., FJU http://www.weco.net
Small-world network(7/7)
Small-world in the brain Truncated power law Economical(close, cost, conservation) Global efficiency, short cut High degree nodes are less often highly
clustered Isomorphism, patterns of connectivity Robust, less vulnerable, balance
04/12/2023 14WECO Lab, CSIE dept., FJU http://www.weco.net
Scale-free network(1/3)
The problem of ER and WS model The probability with which a new vertex
connects to the existing vertices is not uniform
Most real world networks are open. The number of vertices may increase
04/12/2023 15WECO Lab, CSIE dept., FJU http://www.weco.net
Scale-free network(2/3)
Two mechanisms Networks expand continuously by the
addition of new vertices New vertices attach preferentially to sites
that are already well connected The development of large networks is
governed by robust-organizing phenomena
04/12/2023 16WECO Lab, CSIE dept., FJU http://www.weco.net
Scale-free network(3/3)
Power law distribution Citation of scientific papers Rich-get-richer
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Reentrant mapping(1/3)
Directions Corticocortical Thalamocortical Corticothalamic
Mutual information
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Reentrant mapping(2/3)
Theory of Neuronal Group Selection
04/12/2023 19WECO Lab, CSIE dept., FJU http://www.weco.net
Reentrant mapping(3/3)
Reentrant mapping and consciousness
04/12/2023 20WECO Lab, CSIE dept., FJU http://www.weco.net
Undirected and Directed graph(I/O)? Hubs/weighted graph ? Does a vertex which connect to a hub
increase the probability of being attached?
The region between small-world and scale-free?
Links, issues, and opinions(1/4)
04/12/2023 21WECO Lab, CSIE dept., FJU http://www.weco.net
Links, issues, and opinions(2/4)
Three types of projections and structural, functional, and effective point of view
Micro/macro, local/global Structural-functional relation Reconfiguration, dynamics Is the hypothesis of reentry right?
04/12/2023 22WECO Lab, CSIE dept., FJU http://www.weco.net
Links, issues, and opinions(3/4)
What parameters can be mapped from brain to social networks?
Small-world
Degeneracy?
04/12/2023 23WECO Lab, CSIE dept., FJU http://www.weco.net
What’s the stimulus of social network? What stimulus force the structure of
social networks change? What characteristics should a brain
simulator has? Degeneracy, evolutionary, self-organize,
etc…
Links, issues, and opinions(4/4)
04/12/2023 WECO Lab, CSIE dept., FJU http://www.weco.net
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Reference [1] Ed Bullmore, Olaf Sporns, “Complex brain networks: graph
theoretical analysis of structural and functional systems”, Nature Reviews Neuroscience 10, 186-198 (March 2009)
[2] Duncan J. Watts, Steven H. Strogatz, “Collective dynamics of 'small-world' networks”, Nature 393, 440-442 (4 June 1998)
[3] Albert-László Barabási, Réka Albert, “Emergence of Scaling in Random Networks”, Science 15 October 1999: Vol. 286. no. 5439, pp. 509 – 512
[4] Gerald M. Edelman, “Wider than the Sky: The Phenomenal Gift of Consciousness”, Yale University Press (March 10, 2004)