bridge head system momenclature

7
Nomenclature of bridge head heterocycles Dr Taj Khan Dept. of Pharmaceutical Chemistry, OCP, Sanpada, New Mumbai.

Upload: taj-khan

Post on 19-Jan-2017

55 views

Category:

Education


0 download

TRANSCRIPT

Page 1: Bridge head system momenclature

Nomenclature of bridge head heterocycles

Dr Taj Khan Dept. of Pharmaceutical Chemistry, OCP, Sanpada, New Mumbai.

Page 2: Bridge head system momenclature
Page 3: Bridge head system momenclature

Two carbons forming each bridge will always be “cis” to each otherBoth hydrogens are on the same side

Page 4: Bridge head system momenclature
Page 5: Bridge head system momenclature
Page 6: Bridge head system momenclature
Page 7: Bridge head system momenclature

Both “bridgehead” positions are on the same C, so cant use “bicyclo” nomenclature as before-  but the process is very similar.  simply substitute “spiro” for “bicyclo” , insert the two bridge lengths, and place the suffix as before.