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Flexible Solutions for Dilution

CyBi®-InLine FamilyProducts for Dilution Series and Reaction Set-Up

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2 | CyBi®-InLine Family | Products for Dilution Series and Reaction Set-Up

General Features

Over the last few years, biological and chemical research applications have changed considerably. With the standardization of many assay- and molecular biology-based techniques, automation requirements now include both excellent reproducibility and high throughput.

With more than 20 years of experience, CyBio is a leading manufacturer of high quality liquid hand-ling technologies and automation solutions. In the pharmaceutical and life science industries, CyBio‘s products enjoy the highest reputation for precision, reliability and simplicity.

The CyBi®-InLine Family provides automated liquid handling devices with 8 or 16 pipetting channels for column by column tasks within the volume range from 0.5 µl up to 1000 µl: CyBi®-InLine 16/25 µl, CyBi®-InLine 8/1000 µl and CyBi®-InLine 8+1/250 µl.

The CyBi®-InLine 16/25 µl adresses applications in the 384-well format whereas the CyBi®-InLine 8/1000 µl was designed for working in 96-(deep) well plates.

In addition, there is also a single channel with the CyBi®-InLine 8+1/250 µl which can access single tubes as well as single wells of a microplate.

CyBi®-InLine 8+1/250 µl

CyBi®-InLine 16/25 µl

CyBi®-InLine 8/1000 µl

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CyBi®-InLine Family | Products for Dilution Series and Reaction Set-Up | 4

Like all other products developed by CyBio, the CyBi®-InLine pipettors are avail-able with several options and multiple configuration choices. Thus, CyBio offers you the perfect pipetting system for the automation of your assay or application.

You can set up your system with a main linear transport system with 3, 4 or 5 positions. For complex applications requiring more positions for microplates, reservoirs and tips, the system can be upgraded with additional positions on a second transport system. The modular concept of the CyBi®-InLine Family allows an easy upgrade with other CyBio devices, such as the CyBi®-Drop for dispensing of cells and liquids, a 96- or 384-multichannel pipettor for simultaneous pipetting, or stackers for storage of plates. Other accessories like barcode reader, tip wash station, automated reservoir refillable and adapters for reagent heating or cooling as well as the additional position carriage are also available. This allows future changes in throughput or lab requirements, without knowing what future requirements will be.

Make the Right Choice and Find Your Configuration

Choose the Right Accessory for Your CyBi®-InLine

Benefits

» Fully automated assays

» High storage capacity for plates and tip racks

Application

» Increasing throughput

» AutomationCyBi®-QuadStack

Benefits

» Gentle dispensing of cell suspension without mechanical stress

» Gentle dispensing of reagents on the top of adherent cell monolayers

» Fast and flexible contact-free filling of microplates with different liquids

Application

» Cell-based assays

» Contact-free reagent dispensing

CyBi®-Drop

Benefits

» Different multichannel pipetting heads for working with 96-, 384- and 1536-well plates

» Fast and reliable replication and reformatting

» Large volume range from 25 nl - 1000 µl

Application

» Increasing throughput

» More complex and flexible assays

CyBi®-Well vario

Contact-free dispenser

Storage with four stacks

96- and 384-channel simultaneous pipettor

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Make the Right Choice and Find Your CyBi®-InLine

Benefits

» Saves time with the combination of 1 and 8 channels on one pipetting head without head exchange

» Allows processing of whole micro-plates, columns and single wells as well as tubes

» Allows automation of more complex applications

Benefits

» More walk away time through transfer of large sample volumes

» Microplate database supersedes necessity of teaching

Benefits

» More walk away time through 16-channel pipetting for 384-well plates

» Improves reliability and precision for 384-well applications

Application

» Reaction set-up: PCR set-up, qPCR set-up, sequencing set-up

» Serial dilution: EC50, IC50 in a 96-well plate

» Tube to plate transfer

» Medium throughput hit picking

Application

» Using high volume deep well plates and reservoirs

» Serial dilution: EC50, IC50 in 96- (deep) well plates

Application

» Low throughput plate replication and reformatting

» Serial dilution: EC50, IC50 in a 384-well plate

» Reagent transfer from different reservoirs

CyBi®-InLine 8+1/250 µl

CyBi®-InLine 8/1000 µl

CyBi®-InLine 16/25 µl

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info@cybio-ag.com www.cybio-ag.com Tech

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CyBio AG

Goeschwitzer Strasse 40 07745 JenaGermanyTel +49.3641.351 0Fax +49.3641.351 409

CyBio US, Inc.

500 West Cummings ParkSuite 1800Woburn, MA 01801, USATel +1.781.3 76 98 99Fax +1.781.3 76 98 97

CyBio Northern Europe Ltd.

8 James Whatman Court, Turkey MillAshford Road, MaidstoneKent ME 14 5SS, UKTel +44.16 22 66 21 18 Fax +44.16 22 66 41 57

01.15.01.01.12.01.750 / Photos: © abcmedia - Fotolia.com © CyBio AG

6 | CyBi®-InLine Family | Products for Dilution Series and Reaction Set-Up

Customized Liquid Handling Workstation

Barcode Reader

Barcode reading on short or long side with implemented pro-cessing in the software

Stacker

Storage of different microplate types as well as reservoirs, tip racks and tip boxes

CyBi®-Drop

Gentle dispensing of cell suspensions or fast, contact-free addition of reagents with 8 or 16 channels

Multichannel Head

Replication or reformatting of microplates realized through exchangeable or fixed pi-petting heads with 96, 384 or 1536 channels covering a volume range from 0.5 µl - 1000 µl

Your Regional Contact:

CyBi®-InLine Family

Pipetting of dilution series, hit picking and tube to well tasks, depending on application and the appropriate product of CyBi®-InLine Family

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