bsd 2016 case 36 - virtual pathology 201… · •clear cell acanthoma of degos. diagnosis •clear...

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BSD 2016 CASE 36

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Page 1: BSD 2016 CASE 36 - Virtual Pathology 201… · •Clear Cell Acanthoma of Degos. Diagnosis •Clear Cell Acanthoma of Degos. Author: asok biswas Created Date: 8/14/2016 10:03:33 PM

BSD 2016 CASE 36

Page 2: BSD 2016 CASE 36 - Virtual Pathology 201… · •Clear Cell Acanthoma of Degos. Diagnosis •Clear Cell Acanthoma of Degos. Author: asok biswas Created Date: 8/14/2016 10:03:33 PM

Clinical History

• Male 67 years

• Lesion on left thigh

• Differential Diagnosis

• Traumatised seborrhoeic keratosis

• Bowen’s disease/SCC

• Insect bite

• Leshmaniasis

Page 3: BSD 2016 CASE 36 - Virtual Pathology 201… · •Clear Cell Acanthoma of Degos. Diagnosis •Clear Cell Acanthoma of Degos. Author: asok biswas Created Date: 8/14/2016 10:03:33 PM

Histology

• Orthokeratin and parakeratin

• Elongation of rete pegs

• No dysplasia of the squamous epithelium

• Abrupt clear cell differentiation

• Neutrophilic infiltrate into epidermis

Page 4: BSD 2016 CASE 36 - Virtual Pathology 201… · •Clear Cell Acanthoma of Degos. Diagnosis •Clear Cell Acanthoma of Degos. Author: asok biswas Created Date: 8/14/2016 10:03:33 PM
Page 5: BSD 2016 CASE 36 - Virtual Pathology 201… · •Clear Cell Acanthoma of Degos. Diagnosis •Clear Cell Acanthoma of Degos. Author: asok biswas Created Date: 8/14/2016 10:03:33 PM
Page 6: BSD 2016 CASE 36 - Virtual Pathology 201… · •Clear Cell Acanthoma of Degos. Diagnosis •Clear Cell Acanthoma of Degos. Author: asok biswas Created Date: 8/14/2016 10:03:33 PM
Page 7: BSD 2016 CASE 36 - Virtual Pathology 201… · •Clear Cell Acanthoma of Degos. Diagnosis •Clear Cell Acanthoma of Degos. Author: asok biswas Created Date: 8/14/2016 10:03:33 PM
Page 8: BSD 2016 CASE 36 - Virtual Pathology 201… · •Clear Cell Acanthoma of Degos. Diagnosis •Clear Cell Acanthoma of Degos. Author: asok biswas Created Date: 8/14/2016 10:03:33 PM
Page 9: BSD 2016 CASE 36 - Virtual Pathology 201… · •Clear Cell Acanthoma of Degos. Diagnosis •Clear Cell Acanthoma of Degos. Author: asok biswas Created Date: 8/14/2016 10:03:33 PM
Page 10: BSD 2016 CASE 36 - Virtual Pathology 201… · •Clear Cell Acanthoma of Degos. Diagnosis •Clear Cell Acanthoma of Degos. Author: asok biswas Created Date: 8/14/2016 10:03:33 PM
Page 11: BSD 2016 CASE 36 - Virtual Pathology 201… · •Clear Cell Acanthoma of Degos. Diagnosis •Clear Cell Acanthoma of Degos. Author: asok biswas Created Date: 8/14/2016 10:03:33 PM

Histological Differential Diagnosis

• Psoriasis

• Clear Cell Acanthoma of Degos

Page 12: BSD 2016 CASE 36 - Virtual Pathology 201… · •Clear Cell Acanthoma of Degos. Diagnosis •Clear Cell Acanthoma of Degos. Author: asok biswas Created Date: 8/14/2016 10:03:33 PM

Diagnosis

• Clear Cell Acanthoma of Degos