bupsr_rabbits_sot poster full image
DESCRIPTION
Scientific poster showing efficacy of a sustained release buprenorphine injection in rabbits for pain control.TRANSCRIPT
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DEVELOPMENT OF SUSTAINED RELEASE BUPRENORPHINE FOR USE AS AN IMPROVEDANALGESIC IN TOXICOLOGY STUDIES: ASSESSMENT OF FORMULATION PHARMACOKINETICS
Abstract 502Poster 320
Koetzner, Lee1; Stokes, William2; Lance, William3; Wnorowski, Gary1; South, Natalie4; Boulet, Jamie11. Product Safety Labs, Dayton, NJ, US; 2. Kelly Services on behalf of NIEHS, Research Triangle Park, NC, US; 3. Wildlife Pharmaceuticals, Fort Collins, CO, US; 4. Battelle, Columbus, OH, US
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Background and literature
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Conclusions
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Results 2: Observations
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Materials and methods
Product Safety Labs
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1.0
1.5
Baseline
Buprenorphine HCl (IR) 0.015 mg/kg
NMP-SR buprenorphine 0.1 mg/kg
Buprenorphine SRTM
-Lab 0.1 mg/kg
Time (vs. dose, hours)
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Results 1: Pharmacokinetics
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Results 3: Body weight and food consumption
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