by ifsha akhlaq
DESCRIPTION
new suggested treatment of rickets which can be effectiveTRANSCRIPT
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By Ifsha Akhlaq
New suggested treatment of
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Definition Symptoms Causes Risk factors Complications Mechanism of vitamine D production Mechanism of rickets Present treatment My suggestion
Contents
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Rickets is the softening and weakening of bones in children, usually because of an extreme and prolonged vitamin D deficiency.
Definition
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Delayed growth Pain in the spine, pelvis and legs Muscle weakness Bowed legs Thickened wrists and ankles Breastbone projection
Symptoms
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Deficiency in Vitamin D Calcium phosphorous
Caused by
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Age Dark skin Premature birth Anti-seizure medications Exclusive breast-feeding.
Risk factors
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If left untreated, rickets may lead to: Failure to grow Abnormally curved spine Skeletal deformities Dental defects Seizures
Complications
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Mechanism of vitamine D production
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In rickets condition
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vitamin D and calcium supplements Surgical and other procedures
Present treatment
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During breast feeding give oral vitamin D daily(400 IU drops)
Increase the activity of 1 α hydroxylase Decreased the activity of 24 hydroxylase
My suggested treatment
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Rocaltrol Which is commonly used in managment of
hyperparathyriodismAlso enhances calcium absorption
Use other drugs
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Calderol commonly used as hypoparathyroid agents in some areas also used as vitamin d in the
treatment of rickets
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PTH increases the activity of 1-α-hydroxylase enzyme, which converts 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol, the active form of vitamin D.
Role of parathyroid hormone in rickets
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We can increase the production of parathroid hormone
Suggested treatment
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http://www.mayoclinic.com http://www.betterhealth.com http://www.rxlist.com Journal of immunology Baltimore,Md:1950
Referances
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