Your UrologyThe Department of UrologyWelcomes New Chief ofPediatric UrologyChief of Pediatric Urology

UC Irvine Department of Urology andChildren’s Hospital of Orange County

Spring 2008

Tony E. Khoury, M.D.Professor of Urology

Dr. Tony E. Khoury is a world-renowned pediatric urologist, having most recently served asProfessor of Urology and DivisionHead of Pediatric Urology at theUniversity of Toronto, Departmentof Surgery, Hospital for SickChildren, in Toronto, Ontario,Canada.

In coming to Southern California, Dr. Khoury will assume the position of Chief of Pediatric Urology atboth UC Irvine Medical Center andChildren's Hospital of OrangeCounty.

Dr. Khoury is co-editor of the defin-itive pediatric urology textbook,The Kelalis-King-Belman Textbookof Clinical Pediatric Urology(January 2007). His surgical skillsare exemplary and broad in nature,covering all aspects of pediatricurologic surgery from transplanta-tion to the most complicated inter-sex reconstructive procedures. He will also be working closely withUC Irvine scientists to pursue hiskeen interest in tissue bioengineer-ing research.

For appointments and referrals,please call: Tony E. Khoury, M.D. Office: 714.456.3838

UNIVERSITY of CALIFORNIA, IRVINE HEALTHCARE

In its ongoing efforts to provide thehighest quality care for the children ofOrange County, the Department ofUrology at University of California,Irvine is proud to announce the successful recruitment of Dr. TonyKhoury. Dr. Khoury served as theChief of Pediatric Urology at theworld-renowned Hospital for SickChildren in Toronto, Canada for thepast 13 years. There he helped buildthe program into one ofthe world's largest pedi-atric urology facilities,based on the number ofpatients receiving care, thenumber of physician visi-tors, and the number offellows trained. Dr. Khoury's wealth of experience inpediatric urology is sure to propel theclinical and educational standards ofthe Southern California community toan advanced new level.

The long-term goal of the Departmentof Urology is to develop a pediatricurology center of excellence that isrecognized as a tertiary referral cen-ter for Southern California under Dr. Khoury’s guidance. It is hopedthat the center will become renownednationally and internationally for itsexpertise in the medical and surgicalmanagement of complex pediatricurology anomalies, reconstructivechallenges for incontinence, genitalanomalies, renal transplantation, andoncology.

Adolescents and Adults withPediatric Urological IssuesThe care for children with major uro-logical problems such as bladder andcloacal exstrophy, proximal hypospa-dias, prune belly syndrome, or pos-terior urethral valves does not endwhen they reach puberty. Many ofthe concerns are life long and requireongoing medical and psychosocialcare. Occasionally these young

adults may require reconstructive sur-gery to adjust or correct problemsthat evolve following the pubertalgrowth spurt and associated bodyhabitus changes. To that end a newmultidisciplinary service will be estab-lished under Dr. Khoury’s guidancefor patients graduating from the pedi-atric urology clinic to provide care andcounseling for this growing popula-tion. continued on page 2

Over the next few months severalmultidisciplinary teams will be formedto provide comprehensive care for themany children in Orange County with

genitourinary problems.

Esequiel Rodriguez Jr., M.D.Assistant Clinical Professor of Urology

UC Irvine Department of Urology

continued from page 1

Disorders of Sexual Differentiation(DSD) ClinicWhether it be a severe form ofhypospadias or a virilized female,these children and their families con-tend with difficult management deci-sions. In order to help the familiesand children understand the issuesrelated to DSD and help them makethe most appropriate informed choice,a multidisciplinary service includingUC Irvine specialists from genetics,endocrinology, psychology, psychiatry,gynecology, social work and urologyis sure to provide an expert opinion ina caring, reassur-ing environmentfor the optimummanagement.The ultimate goalis to achieve thebest medical andquality-of-life out-comes for thepatients and theirfamilies.

Bladder Exstrophy CareBladder and cloacal exstrophy areformidable congenital anomalies thatdemand a high level of technical skillcombined with years of experience incaring for these children. It was atthe Hospital for Sick Children inToronto that Dr. Robert Jeffs initiallydescribed his groundbreaking tech-niques for repairing bladder exstro-phy, before eventually moving toJohns Hopkins. In his 20-year tenureat the Hospital for Sick Children, Dr.Khoury looked after a large exstrophypopulation from infancy through adult-hood. With this unmatched experi-ence, UC Irvine Pediatric Urology ispositioned to make a significant differ-ence in the lives of children born withthis rare complex defect.

Perinatal UrologyGenitourinary anomalies are one ofthe more common problems discov-ered prenatally (in 1% of routinematernal-fetal ultrasounds). Under-standably, this creates considerableangst for the expectant parents.

Our UC Irvine Pediatric Urology teamwill provide pre- and postnatal diag-nosis as well as treatment and man-agement of infants with disorders ofthe genitourinary tract. Counselingregarding the diagnosis, prognosisand the role of interventional tech-niques in utero for the identificationand management of these challengeswill be provided in a comfortable,understanding setting for the entirefamily.

Minimally Invasive SurgeryUC Irvine Urology is internationallyrenowned for leading innovation inthe field of minimally invasive surgery.

Using laparoscopic, robotic-assistedand endoscopic surgical procedures,a variety of kidney disorders, vesi-coureteral reflux and urinary inconti-nence can be corrected with minimaldiscomfort to the child.

Pediatric Lower Urinary Tract (P-LUT) Dysfunction andNeurourologyThe pediatric voiding dysfunctionsymptom score developed in Torontois now the international standardobjective measure for the evaluationof children with incontinence. In achild-friendly environment, severalnoninvasive techniques are used toaid the family in managing toilet-train-ing issues. Children with complexneurological anomalies such asmyelodysplasia and related spinaldisorders will benefit from advanceddiagnostic and interventional tech-niques to correct or minimize theimpact of these disorders on thechild's quality of life.

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We are committed to providing family-centeredcare in a compassionate and respectful

environment. Children will benefit from a planof care that will be designed based on their

individual needs and family situation.

Dr. Esequiel Rodriguez has specif-ic interests in laparoscopy, roboticsurgery, and pediatric urology. Hewill serve an important role in ourprogram in educating our residentswhile providing outstanding urologiccare to the pediatric population ofOrange County. In addition, Dr.Rodriguez has an appointment inthe PRIME-LC program at UC Irvineand will provide much needed edu-cational opportunities in healthcareto the Hispanic community. Dr.Rodriguez is fluent in Spanish.

Dr. Rodriguez completed his under-graduate studies at the University ofCalifornia at Berkeley where hegraduated with honors in GeneralScholarship. He received his med-ical degree from Stanford UniversitySchool of Medicine. Dr. Rodriguezcompleted his urology residency atUC Irvine Medical Center under Dr.Ralph Clayman. He completed aone-year fellowship in robotic sur-gery under the tutelage of Dr.Thomas Ahlering. Dr. Rodriguezhas published manuscripts and bookchapters in robotic surgery in urolo-gy and has presented his work atnational and international confer-ences.

For appointments and referrals,please call: Esequiel Rodriguez Jr., M.D.Office: 714.456.7005 For the benefit of all of the

children of Orange County,a new day has arrived atUC Irvine Medical Center.

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Program in MedicalEducation for theLatino Community(PRIME-LC), a NationalModel

Dr. Esequiel Rodriguez was successful in securing ½ FTE forhis work in the PRIME-LC efforts.This is a crucial mission of theUniversity of California, IrvineSchool of Medicine designed toeducate highly qualified physiciansto serve the diverse populations ofCalifornia. PRIME-LC is one ofthe signature programs and anational model for meeting thehealthcare needs as Latinosbecome the largest populationgroup in California. In response toan increasing need for highly qualified, culturally sensitive andlinguistically competent physician-leaders, PRIME-LC graduates willimpact healthcare access and out-comes in the local communitiesthrough a variety of mechanismswith which to influence tomorrow'shealth systems. Along with theM.D. degree, a master’s degreeprepares clinician leaders tobecome advocates and activists inthe underserved Latino communi-ties with opportunities to developexpertise in academic medicine,telemedicine, public health, healthcare disparities, research,public policy and other relatedfields. PRIME-LC also providesstrong emphasis on graduate leveltraining in the culture, society, lan-guage, history and beliefs of theLatin American people and USLatinos.

The innovativePRIME-LC program will behoused in thenew medicaleducation build-ing located onthe UC Irvine campus.

Orange County HighSchool Students HaveCareer Day LearningOpportunity at theAstellas SurgicalEducation Center

Beginning in June 2008, over the next 2-3 years, Dr. Ralph Clayman andDr. Elspeth McDougall will provide approximately 53 career day sessions,one for each high school in Orange County. During each session, the stu-dents will be provided with lectures on the future of medicine and medicaltechnology, videotaped medical procedures, and hands-on demonstrationswith the surgical simulators and the da Vinci® RoboticSurgical System. The Astellas Surgical Education Center isan ideal facility for providing students with career explorationopportunities in medicine.

For more information, please contact Rosanne Santos.Office: 714.456.8176

1) Rated among the top 20 programs in the United States by U.S. News & World Report.

2) Among the top 50 urology programs rated by the U.S. News & World Report, we achieved the lowest mortalityrate.

3) We are among the leaders in laparoscopic surgery (minimally invasive surgery) in Orange County when it comes to less invasive surgery for cancer (prostate, kidney, bladder, and testis), kidney stones, or urinary tract obstruction.

4) Our robotic technology and robotic surgery place us among the top programs in the United States. This year,we performed the first surgery in California on the latest da Vinci® S HD™Robotic Surgical System, equipped withhigh definition display.

5) Our outstanding team consists of nine full-time faculty,four part-time faculty, and four PhDs.

Significant Facts about theDepartment of Urology

Your UrologySpring 2008, Issue 9The urology newsletter is published bian-nually. We welcome your comments andideas for stories. Please send them to Dr. Elspeth McDougall, editor, atcshell@uci.edu; make sure to let us knowif we have permission to reproduce yourcomment in full or in part in Your Urology.Copyright © 2008 The Regents of theUniversity of California. All rightsreserved.Department ChairmanRalph V. Clayman, M.D.Newsletter EditorElspeth M. McDougall, M.D., FRCSCNewsletter CoordinatorCynthia Shell

If you do not want to receive further com-munications from the Department ofUrology, please contact Cynthia Shell.

UC Irvine Medical CenterDepartment of Urology333 City Blvd. West, Suite 2100Orange, CA 92868Tel: 714.456.5371

Mission Through excellence and leadership inpatient care, education, and research, theDepartment of Urology will provide itspatients with the absolute best in innova-tive, less invasive urological care; itsresidents with a superb curriculum-basededucational and operative training experi-ence; and its faculty with every opportunityto excel clinically while teaching and pur-suing research of both a basic and clinicalnature.

Vision By virtue of clinical and research accom-plishments, the Department of Urologyseeks to become recognized as one of thetop 10 programs in Urology in the UnitedStates.

Harry W. Herr, M.D.Professor of UrologyMemorial Sloan-KetteringCancer CenterNew York, NY

The 2007 John W. Posey Visiting ProfessorDecember 20-22, 2007

The Department of Urology was pleased to host Dr. Harry Herr as the 2007John W. Posey Visiting Professor, December 20-22, 2007. Dr. Herr providedlectures over the three days on topics related to his area of expertise inreconstructive urologic cancer surgery for our department and surroundingcommunity urologists. In addition, Dr. Herr taught a dedicated, hands-on surgery laboratory session for our eight residents to instruct them in the techniques of urinary diversion surgery.

Ian M. Thompson Jr., M.D.Professor and ChairDepartment of Urologic SurgeryUniversity of TexasHealth Science CenterSan Antonio, TX

Urology Visiting ProfessorMarch 6-8, 2008

Dr. Ian M. Thompson accepted an invitation to be our visiting professor March 6-8, 2008. The Urology Departmentfaculty, fellows, residents, medical students and communityurologists enjoyed Dr. Thompson’s lectures over the threedays on the prevention, detection and treatment of prostatecancer. In addition, Dr. Thompson taught a hands-on cadav-eric laboratory session for the eight urology residents on thesurgical techniques of RPLND (retroperitoneal lymph nodedissection) for the treatment of testicular cancer.

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Department of UrologyVisiting Professors

Ralph V. Clayman, M.D.Professor and ChairmanDepartment of UrologyDr. Clayman is world renowned for his clinical and laboratorywork in minimally invasive surgery. He specializes in the treat-ment of kidney stones, kidney cancer, strictures of the ureter andall other aspects of renal and ureteral diseases.For appointments and referrals, please call:714.456.3418

Thomas E. Ahlering, M.D.Professor and Vice ChairmanDr. Ahlering is well known for laparoscopic radical prostatectomyusing the da Vinci® Robotic Surgical System. He specializes intreatments for cancer of the prostate, bladder, kidney, and testis.He did his postgraduate fellowship training in UrologicalOncology at University of Southern California, Los Angeles. For appointments and referrals, please call:714.456.6068

Tony E. Khoury, M.D.Professor and Chief of Pediatric UrologyDr. Khoury is world renowned for his expertise in the medical andsurgical management of complex pediatric urology anomalies,including reconstructive surgery for incontinence, genital anomalies,renal transplantation and oncology. He did his postgraduate fellow-ship training in Pediatric Urology at the Hospital for Sick Children inToronto, Ontario, Canada.For appointments and referrals, please call:714.456.3838

Regina M. Hovey, M.D.Associate Clinical ProfessorDirector, Urology Residency ProgramDr. Hovey specializes in female urology, urinary incontinence,neurourology, and lower urinary tract reconstruction. She did herpostgraduate fellowship training in Female Urology, Neurourologyand Reconstructive Urology at University of California, Davis.For appointments and referrals, please call:714.456.7128

Elspeth M. McDougall, M.D., FRCSCProfessor of Urology andAssociate Dean, Clinical Science EducationDr. McDougall specializes in minimally invasive surgery for thetreatment of kidney stones, kidney cancer and strictures of theureter. She did her postgraduate fellowship training in Endourologyand Extracorporeal Shock Wave Lithotripsy at WashingtonUniversity Medical School, Barnes Hospital, St. Louis, MO.For appointments and referrals, please call:714.456.7005

Jerry B. Miller, M.D.Clinical ProfessorDr. Miller specializes in general practice urology and supervisesresidents-in-training in the general urology clinic.For appointments and referrals, please call: 714.456.7005

Leland Ronningen, M.D.Associate Clinical ProfessorDr. Ronningen is particularly interested in benign diseases of theprostate and practices general urology.For appointments and referrals, please call:714.456.7127

Nader Sadoughi, M.D., FACSClinical ProfessorDr. Sadoughi’s interest and expertise are in urologic oncologicsurgery and neuromuscular dysfunction of the lower urinary tractfor urinary incontinence. He is actively involved in teaching urology residents at the VA Long Beach Healthcare System,where he sees patients. He did his postgraduate fellowshiptraining at Sloan Kettering Cancer Center in New York.For appointments and referrals, please call:562.826.5434

Anne R. Simoneau, M.D.Associate Clinical ProfessorAssistant Director, Urological OncologyDr. Simoneau has clinical trials in prostate cancer preventionand is working in the laboratory on bladder cancer prevention.She did her postgraduate fellowship training in Clinical UrologicalOncology at University of Southern California, Los Angeles. For prostate cancer prevention, please call:714.456.3330

.

David K. Ornstein, M.D.Assistant Professor and Director, Urological OncologyDr. Ornstein completed a fellowship in urologic oncology at theNational Cancer Institute. He now treats patients with all typesof urologic cancers. He has extensive experience with open,laparoscopic, and robotic surgery, and is particularly interested inpotency and continence-sparing radical prostatectomy using theda Vinci® Robotic Surgical System.For appointments and referrals, please call:714.456.5378

Aaron Spitz, M.D.Assistant Clinical ProfessorMale Reproductive Medicine and SurgeryDr. Spitz has expertise in the treatment of male infertility andsexual dysfunction. He did his fellowship training at BaylorCollege of Medicine, Houston, TX. For appointments and referrals, please call:714.456.7005

Atreya Dash, M.D.Assistant Clinical ProfessorDr. Dash completed a fellowship in urologic oncology at MemorialSloan-Kettering Cancer Center in New York. He has experiencein all areas of urologic oncology including the advanced surgicaltreatment of prostate, renal, testis and bladder cancers. Hispatient treatment modalities include minimally invasive surgicaltechnologies such as laparoscopy to improve the care and convalescence of patients with urologic cancers.For appointments and referrals, please call:714.456.7005

Esequiel Rodriguez, M.D.Assistant Clinical ProfessorDr. Rodriguez has specific interests in pediatric and robotic sur-gery. He has an appointment in the PRIME-LC program at UCIrvine and will provide much-needed educational opportunities inhealthcare to the Hispanic community. He completed a fellow-ship in robotic surgery at UC Irvine under the tutelage of Dr.Thomas Ahlering. For appointments and referrals, please call:714.456.7005

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UC Irvine Healthcare Department of Urology Clinical Faculty

Department of Urology333 City Blvd. West, Suite 2100

Orange, CA 92868-5395

Driving Directions to UC Irvine Medical Center -- From I-5 take the Chapman Avenue exit. Drive westbound on Chapman. Turn left (south) onto The City Drive South. Proceed to Dawn Way. Turnleft. The UC Irvine Medical Center visitor parking structure is on the left side. Upon exiting the parking structure after parking, continue down thebroad walkway until you see Miss Kelly's Coffee Cart on your right side. On your left side is the entry to the Pavilion III urology offices. If you are lost, please call 714.456.7005.

Visit the Department of Urology on the Web at -- www.ucihs.uci.edu/urologyUC Irvine Healthcare - Urology Newsletter Spring 2008

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