calma * capili * dagang * dayrit. fv fv 49/m 49/m married, roman catholic, from canlubang laguna...
TRANSCRIPT
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A Case of a man with relentless headache
Calma * Capili * Dagang * Dayrit
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General DataFV
49/M
Married, Roman Catholic, from Canlubang Laguna
Admitted to the PGH ER last April 2, 2010
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Chief ComplaintHeadache for 5 months
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History of Present Illness
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History of Present Illness
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(+) weight loss (25% in 5 months)
(-) anorexia
(-) fever
(-) cough, colds
(-) difficulty of breathing
(-) chest pain
Review of Systems
(-) abdominal pain
(+) 3 P’s
(-) bowel complaints
(-) seizures
(-) loss of consciousness
(-) edema
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Past Medical History(+) HPN – since 2000, UBP 160/100,
HBP 180/120, (-) maintenance medications
(+) DM – since 2003, (-) maintenance medications
(-) PTB, BA, allergies, history or trauma, previous surgeries
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Family Medical History(+) HPN – father
(-) DM, PTB, BA, CA
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Personal Social HistoryTruck driver, married with 6 children
Non-smoker, occasional alcoholic beverage drinker, (-) illicit drug use
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Physical ExaminationBP 130/90 HR 90 RR 20
PC, AS, (-) CLAD, (-) ANM
ECE, CBS, (-)crackles/wheezes
(-) heaves/thrills, DHS, NRRR, AB 5th ICS LAAL, (-) murmurs
Abdomen flat, NABS, soft, non-tender
FEP, PNB, (-) clubbing, (-) edema
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Neurologic ExaminationGCS 15, alert, awake, oriented to 3
spheres
Cranial NervesI Not assessed
II Pupils 3 mm EBRTL, VA: OD 20/40, OS 20-40-2, (-) visual field cuts
III, IV, VI
(+) LR palsy OS
V V1: R 100% L 10%; V2: R 100% L 10%; V3: B 100%
VII Shallow L NLF, (+) L central facial palsy
VIII Webber: Lateralized to the L, Rinne: AS: BC>AC
IX, X Good gag
XI Good shoulder shrug
XII Tongue midline
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Neurologic ExaminationMotor
Good muscle bulk, (-) spasticity, (-) flaccidity
5/5 5/5
5/5 5/5
Sensory
100% 100%
100% 100%
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Neurologic Examination DTRs
++ ++
++ ++
++ ++
Cerbellars: (-) dysmetria, (-) dystiadochokinesia
Meningeals: (-) nuchal rigidity, (-) Kernig’s, (-) Brudzinski
Autonomic
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Cranial CT Scan(+) contrast enhancing tumor, ill
defined involving sellar-supresellar, sphenoidal areas
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Cranial CT ScanInsert plates here
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Cranial MRI with GAD(+) sellar-supresellar mass occupying
the sphenoid sinus as well
(+) encasing B cavernous sinus with invasion of clivus
Impression: Chordoma vs. Invasive Pituitary Adenoma
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Cranial MRI with GADInsert plates here
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Other Laboratory ExamsCBC: 4/2: Hgb 103 Hct 0.309 WBC
7.1 N 0.652 L 0.276 Plt 331
PT/PTT: 4/2: 11.0/12.2/0.89/1.17; 32.6/37.3
4/5: FT4 8.4 (N 11-24 pmol/L), TSH 0.8 (N 0.3-3.8 mIU/L), Cortisol 25 (N 138-690 nmol/L), PRL 3,041.9 (80-430mIU/L)
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Other Laboratory Exams
4/2 4/3 4/6 4/10 4/12 4/16 4/19
Glucose 11.8 10.3
BUN 6.79 5.77 2.46
Crea 117 124 108
Na 127 127 126 126 119 115 132
K 4.1 4 4 4.1 4 3.4
Cl 88 90 90 85 72
Ca 2.23 1.97
Mg 0.68
Urine Na 238
Urine K 11.6
Urine Cl 213
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Course in the ERIn the ER, pt managed primarily by
NSS, co-managed by ORL, Ophtha, and Endo
Pt GCS 15 while in the ER, no motor or sensory deficits.
Pt on the following medications: Mannitol 75 cc IV Q8 Q6, Celecoxib 200 mg/cap Q12, Tramadol 50 mg/tab TID Tramadol 50 mg IV Q8, Ketorolac drip (30 mg in 250cc D5W x 24h), Dexamethasone 5 mg/IV Q6
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Course in the ERORL: A> hearing loss etiology to be
determined. Plan for PTA-ST and for transsphenoidal biopsy/GA once admitted
Ophtha: A> LR palsy probably secondary to malignancy. Refraction done. Plan for visual perimetry.
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Course in the EREndo: A> Consider secondary
hypogonadism, secondary hypothyroidism, secondary hypoadrenalism secondary to suprasellar mass with mass effect. Hyperglycemia probably secondary to DM vs. steroid induced vs. combination. Hyponatremia secondary to SIADH due to tumor, secondary hypothyroidism, secondary to AI, secondary to mannitol use, orsecondary to hyperglycemia. Pt started on Levothyroxine 100 mcg/tab 30 min before breakfast, HN 20-0-10 SQ pre-melas, HR 8-8-8 SQ pre-meals, defer for CBG < 70mg/dL.