capsion. protect, enhance, and save lives - 2 - the 1st criteria of differentiation the formulation...
TRANSCRIPT
![Page 1: CAPSION. Protect, Enhance, and Save Lives - 2 - The 1st criteria of differentiation The formulation ( part 1 ) The addition of ascorbic acid and sodium](https://reader036.vdocument.in/reader036/viewer/2022062516/56649d9c5503460f94a846eb/html5/thumbnails/1.jpg)
CAPSION CAPSION
![Page 2: CAPSION. Protect, Enhance, and Save Lives - 2 - The 1st criteria of differentiation The formulation ( part 1 ) The addition of ascorbic acid and sodium](https://reader036.vdocument.in/reader036/viewer/2022062516/56649d9c5503460f94a846eb/html5/thumbnails/2.jpg)
Protect, Enhance, and Save Lives - 2 -
The 1st criteria of differentiation The formulation ( part 1 )
The addition of ascorbic acid and sodium thiosulfate in the formulation improved the stability (under iodide form) of CAPSION
This original chemical formulation does prevent the oxidation of Iodine allowing to avoid the formation of gazeous Iodine (I2) & the leakage of gazeous Iodine from the capsule
The addition of anhydrous sodium pyrophosphate allows an optimum biodisponibility
![Page 3: CAPSION. Protect, Enhance, and Save Lives - 2 - The 1st criteria of differentiation The formulation ( part 1 ) The addition of ascorbic acid and sodium](https://reader036.vdocument.in/reader036/viewer/2022062516/56649d9c5503460f94a846eb/html5/thumbnails/3.jpg)
Protect, Enhance, and Save Lives - 3 -
The 1st criteria of differentiation The formulation ( part 2 )
A high stabilisation in the iodine [131I] capsule under iodide form (I-)
A high radiochemical purity ( 98%) at release
A rapid external delivery of iodide
in vitro disponibility : 99-100% of the activity is released within 4 minutes
![Page 4: CAPSION. Protect, Enhance, and Save Lives - 2 - The 1st criteria of differentiation The formulation ( part 1 ) The addition of ascorbic acid and sodium](https://reader036.vdocument.in/reader036/viewer/2022062516/56649d9c5503460f94a846eb/html5/thumbnails/4.jpg)
Protect, Enhance, and Save Lives - 4 -
The 2nd criteria of differentiation Primary & secondary packaging
For an easier administration to patient in suitable conditions of radioprotection for the environment and therefore especially safe for the medical staff
![Page 5: CAPSION. Protect, Enhance, and Save Lives - 2 - The 1st criteria of differentiation The formulation ( part 1 ) The addition of ascorbic acid and sodium](https://reader036.vdocument.in/reader036/viewer/2022062516/56649d9c5503460f94a846eb/html5/thumbnails/5.jpg)
Protect, Enhance, and Save Lives - 5 -
PRIMARY PACKAGING
HIGH QUALITY in terms of :
- Physical and behavioural specifications- Residual activity and external radioactivity
![Page 6: CAPSION. Protect, Enhance, and Save Lives - 2 - The 1st criteria of differentiation The formulation ( part 1 ) The addition of ascorbic acid and sodium](https://reader036.vdocument.in/reader036/viewer/2022062516/56649d9c5503460f94a846eb/html5/thumbnails/6.jpg)
Protect, Enhance, and Save Lives - 6 -
SECONDARY PACKAGING
The secondary packaging ensures an optimal radioprotection for the users, with a maximum
dose below the current norms
![Page 7: CAPSION. Protect, Enhance, and Save Lives - 2 - The 1st criteria of differentiation The formulation ( part 1 ) The addition of ascorbic acid and sodium](https://reader036.vdocument.in/reader036/viewer/2022062516/56649d9c5503460f94a846eb/html5/thumbnails/7.jpg)
7
CAPSION : Way of administration
![Page 8: CAPSION. Protect, Enhance, and Save Lives - 2 - The 1st criteria of differentiation The formulation ( part 1 ) The addition of ascorbic acid and sodium](https://reader036.vdocument.in/reader036/viewer/2022062516/56649d9c5503460f94a846eb/html5/thumbnails/8.jpg)
8
The tongs are used to measure the capsule activity
The lead perforator is used to open the vial
The vial is blocked in the lead during administration to patient
The 3rd criteria of differentiation Easy administration
![Page 9: CAPSION. Protect, Enhance, and Save Lives - 2 - The 1st criteria of differentiation The formulation ( part 1 ) The addition of ascorbic acid and sodium](https://reader036.vdocument.in/reader036/viewer/2022062516/56649d9c5503460f94a846eb/html5/thumbnails/9.jpg)
Thank youThank you
CAPSION
A Original chemical formulation+
The excellent radioprotection+
Easy administration