care of the treatment- experienced patient with hcv infection who failed prior therapy

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Care of the Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

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Care of the Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy. Case 53-year-old Black Man. Case (cont). Case (cont). Case (cont). Second Treatment Regimen. Case (cont). Why Is Achieving SVR So Important?. Why Is Achieving SVR So Important?. - PowerPoint PPT Presentation

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Page 1: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Care of the Treatment-experienced Patient With HCV

Infection Who Failed Prior Therapy

Page 2: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Case53-year-old Black Man

Page 3: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Case (cont)

Page 4: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Case (cont)

Page 5: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Case (cont)

Page 6: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Second Treatment Regimen

Page 7: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Case (cont)

Page 8: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Why Is Achieving SVR So Important?

Page 9: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Why Is Achieving SVR So Important?

Page 10: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Potential Treatment Options for the Case Patient

Page 11: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Simeprevir for Treatment-naive Patients

Page 12: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Simeprevir for Treatment-experienced Patients

Page 13: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Sofosbuvir

Page 14: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

COSMOSOff-Label Combination of Sofosbuvir and Simeprevir RBV

in Patients With G1 HCV Infection

Page 15: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

SAPPHIRE-I and SAPPHIRE-II ABT-450/r (protease inhibitor and ritonavir) + ABT-

267 (NS5A inhibitor) + ABT-333 (non-nucleoside polymerase inhibitor) × 12 weeks

Page 16: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

LONESTAR Trial Sofosbuvir and Ledipasvir Fixed-Dose

Combination RBV

Page 17: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

Abbreviations

Page 18: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

References

Page 19: Care  of the  Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

References (cont)