case pres eamc-surgery drug study
TRANSCRIPT
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Domperidone
Motilium film-coated tab Motilium susp
GIT Regulators, Antiflatulents &
Anti-inflammatories,
Antiemetics
Domperidone is a peripheral dopamine-
receptor blocker. It increases oesophageal
peristalsis, lower oesophageal sphincter
pressure, gastric motility and peristalsis, thus facilitating gastric
emptying and decreasing small bowel
transit time.
OralNausea and vomiting
OralNon ulcer dyspepsia
Migraine
Nausea and vomiting
Drowsiness, extrapyramidal
reactions, galactorrhoea, gynaecomastia; constipation or
diarrhoea, lassitude, decreased libido, skin
rash, itch.Potentially Fatal:
Convulsions, arrhythmias and cardiac arrest,
dysrrhythmias in patients with CV
disease or hypokalaemia,
patients on cancer chemotherapy.
Seizures; hypertensive crisis in patients with phaeochromocytoma.
Hypersensitivity. GI haemorrhage,
obstruction and perforation, patients
with prolactin releasing pituitary hormone, chronic admin or routine
prophylaxis of postoperative
nausea and vomiting.
Phaeochromocytoma; children<2 yr, elderly;
renal or hepatic impairment. Risk of cardiac arrhythmias and hypokalaemia if
administered IV. Pregnancy and
lactation.
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Ciprofloxacin
Baxolyn tab
Quinolones, Eye Anti-infectives & Antiseptics,
Ear Anti-infectives & Antiseptics
Baxolyn tab
Ciprofloxacin promotes breakage of double-
stranded DNA in susceptible organisms
and inhibits DNA gyrase, which is essential in
reproduction of bacterial DNA.
For the treatment of infections caused by susceptible gram-negative bacteria, including E. coli, P. mirabilis, K. pneumoniae, Enterobacter cloacae, P. vulgaris, P. rettgeri, M. morganii, P. aeruginosa, Citrobacter freundii, S. aureus, S. epidermidis, group D streptococci
Otic: Treatment of acute otitis externa
Treatment of chronic bacterial prostatitis
IV: Treatment of nosocomial pneumonia caused by Haemophilus influenzae, K. pneumoniae
GI disturbances; headache, tremor,
confusion, convulsions; rashes;
joint pain; phototoxicity.
Transient increases in serum creatinine. Haematological,
hepatic and renal disturbances.
Vasculitis, pseudomembranous
colitis and tachycardia.
Phototoxicity.Potentially Fatal:
Anaphylactoid reaction;
cardiopulmonary arrest
Hypersensitivity. Not to be used
concurrently with tizanidine. Avoid
exposure to strong sunlight or sun lamps during treatment.
Epilepsy, history of CNS disorders; severe renal or hepatic dysfunction;
G6PD deficiency; maintain adequate
hydration; myasthaenia gravis. Caution when used in patients with
QT prolongation or risk factors e.g.
bradycardia, pre-existing cardiac disease
or uncorrected electrolyte
disturbances. Discontinue treatment if patients experience
tendon pain, inflammation or
rupture. Avoid usage in methicillin-resistant
staphylococcus aureus (MRSA) infections due
to high level of resistance. May impair
ability to drive or operate machinery.
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
Oral: Typhoid feverOral: Sexually
transmitted diseases caused by N. gonorrheae
Prevention of anthrax following exposure to anthrax bacilla (prophylactic use in regions suspected of using germ warfare)
Unlabeled use: Effective in patients with cystic fibrosis who have pulmonary exacerbations
Safety and efficacy have not been
established in pregnant and lactating women.
Not to be used in children <18 yr; except where benefit clearly
exceeds risk.
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
Metoclopramide
Biclomet amp
Plasil tab
GIT Regulators, Antiflatulents &
Anti-inflammatories,
Antiemetics
Biclomet amp
Plasil tab
Metoclopramide enhances the motility of the upper GI tract and increases gastric
emptying without affecting gastric, biliary
or pancreatic secretions. It increases
duodenal peristalsis which decreases
intestinal transit time, and increases lower
oesophageal sphincter tone. It is also a potent
central dopamine-receptor antagonist and may also have
serotonin-receptor (5-HT3) antagonist
properties.
Diabetic gastric stasis
Nausea and vomiting associated with
cancer chemotherapy or
radiotherapy
Gastro-oesophageal reflux disease
Prevent delayed emesis following chemotherapy
Premedication in diagnostic
procedures
Nausea and vomiting associated with
cancer chemotherapy
Premedication for radiologic
examination of the upper
gastrointestinal tract
Intubation of the
Extrapyramidal symptoms, restlessness,
drowsiness, anxiety, diarrhoea, hypotension,
hypertension, headache, depression, blood disorders (e.g.
aganulocytosis, methaemoglobinaemia),
hypersensitivity reactions (e.g.
bronchospasm, rash), galactorrhoea or related
disorders, transient increase in plasma aldosterone levels.Potentially Fatal:
Neuroleptic malignant syndrome; cardiac
conduction disorders may occur with IV
dosage form.
GI haemorrhage, mechanical
obstruction and perforation;
phaeochromocytoma; history of seizures.
Children, elderly. Renal or hepatic
impairment, porphyria, epilepsy, Parkinson's disease,
history of depression. Ability to drive or
operate machineries may be impaired.
Pregnancy and lactation. Monitor
patients on prolonged therapy. Increased
risk of tardive dyskinesia in patients on prolonged or high-
dose treatment.
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
small intestine
Postoperative nausea and vomiting
Diabetic gastric stasis
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
Ensure With Fiber® [powd]
Enteral/Nutritional Products
Supplementary or sole source of complete & balanced nutrition in
conditions w/c preclude normal food
intake eg convalescence,
early/uncomplicated carcinoma, coma, pre-op prep, post-op care,
bowel prep, psychological
problems (anorexia nervosa, severe
depression), malnutrition;
chronically ill or elderly patients.
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Salbutamol + Ipatropine
Combivent® [Unit dose vial]
Antiasthmatic & COPD
Preparations
Ipratropium and albuterol combination reduces bronchospasm
through both anticholinergic and sympathomimetic
mechanisms. Simultaneous
administration of both drugs produces a
greater bronchodilator effect than when either
drug is used alone at recommended dosages.
Albuterol—Albuterol is a sympathomimetic agent that has a relatively high degree of selectivity for
beta 2-adrenergic receptors. Activation of
these receptors on airway smooth muscle leads to the activation of the enzyme adenylyl
cyclase and to an
Management of reversible
bronchospasm associated w/
obstructive airway diseases in patients who require more
than a single bronchodilator.
Angioedema (swelling of the face, lips, or
eyelids)
bronchospasm, paradoxical or
hypersensitivity-induced (shortness of
breath; wheezing)
chest discomfort or pain
irregular heartbeat
oropharyngeal edema (swelling of the mouth
or throat)
skin rash
tachycardia (fast heartbeat)
urticaria
Hypertrophic obstructive
cardiomyopathy or tachyarrhythmia.
History of hypersensitivity to
soya lecithin or related food
products (for MDI only).
Insufficiently controlled diabetes mellitus, recent MI, severe organic heart or
vascular disorders, hyperthyroidism,
pheochromocytoma, risk of narrow-angle glaucoma, prostatic
hypertrophy or bladder-neck
obstruction; cystic fibrosis. Pregnancy,
lactation.
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
increase in the intracellular
concentration of cyclic-3, 5-adenosine
monophosphate (cAMP). Increased cAMP
concentrations indirectly lower
intracellular ionic calcium, which results in airway smooth muscle
relaxation.
Ipratropium—Ipratropium is an
anticholinergic agent that produces a local,
site-specific effect rather than a systemic
effect. It appears to produce
bronchodilation by inhibition of cholinergic receptors on bronchial
smooth muscle.
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Ceftriaxone
Rocephin
IV Vial
Third-generation cephalosporins.
Ceftriaxone binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Indications:
Sepsis, meningitis; abdominal, biliary tract, GIT, bone,
joints, soft tissue, renal, resp tract, ENT,
genital & skin & wound infections.
Perioperative prophylaxis of
infections.
Shock, hypersensitivity, blood
abnormality. Liver & kidney failure, GI & resp disturbances, superinfection, vit
deficiency.
-History of shock, hypersensitivity to
cephalosporins, penicillins, anilide local anesthesia.
-Instruct patient to take medication as prescribed for the length of time ordered even if he feels better.
-Teach patient to report sore throat, bruising, bleeding and joint pain.
-Advise patient to watch out for perineal itching, fever, malaise, redness, pain, swelling,
rash, and diarrhea.
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Lactulose
Chronulac
Laxative
Produces an osmotic effect in the colon with
resultant distention promoting peristalsis
To treat constipation. May cause gas, belching or stomach
cramps, diarrhea, nausea, vomiting.
It is contraindicated in patients who
require a low galactose diet.
-Assess usual bowel patterns, use other methods to relieve constipation where possible.
-Do not give if client has abdominal pain, discourage chronic use.
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Omeprazole
Prilosec
Belongs to the class of proton
pump inhibitors.
Mechanism of Action:
Prevent the movement of hydrogen ions from the parietal cell into the stomach, which results to the blocking of all gastric acid secretion.
Short-term treatment of duodenal ulcer, gastric ulcer & erosive esophagitis. Long-term treatment of Zollinger-Ellison syndrome. Treatment of heartburn & other symptoms associated with GERD.
Headache, diarrhea & skin rashes. Pruritus, dizziness, fatigue, constipation, nausea & vomiting, flatulence, abdominal pain, arthralgia & myalgia, urticaria & dry mouth.
Contraindicated in patients with known hypersensitivity to any component of the formulation.
-Assess for allergies and history of liver disease.
-Instruct the patient taking omeprazole:
>It should be taken before meals.>The capsule should be swallowed whole, not crushed, opened, or chewed.>It may be given with antacids.>Emphasize that the treatment will be short term.
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Tramadol
Dolmal
Amp
Analgesics (Opioid)
Mechanism of Action:
Binds to -opiate receptors in the CNS causing inhibition of ascending pain pathways, altering the perception of and response to pain; also inhibits the reuptake of norepinephrine and serotonin, which also modifies the ascending pain pathway
Cap Acute & chronic pain. Amp Moderate to severe pain due to mild illness, pain after diagnosis or post-op pain.
Constipation; diarrhea; dizziness; drowsiness; dry mouth; headache; nausea; trouble sleeping; vomiting; weakness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; chest pain; difficult or painful urination; disorientation; fainting; hallucinations; irregular heartbeat; loss of coordination;
-Acute alcohol intoxication;
-Patients under intoxication w/ hypnotic analgesics or psychotropic drugs
-Severe respiratory depression
-Patients w/ a risk of stupor due to head injuries or lesions; concomitant administration w/ MAOIs.
Assess for level of pain relief and administer prn dose as needed but not to exceed the recommended total daily dose.
Monitor vital signs and assess for orthostatic hypotension or signs of CNS depression.
Discontinue drug and notify physician if S&S of hypersensitivity occur.
Assess bowel and bladder function; report urinary frequency or retention.
Use seizure precautions for patients who have a history of seizures or who are concurrently
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
mood or mental changes (eg, depression); red, blistered, swollen, or peeling skin; seizures; severe dizziness or lightheadedness.
using drugs that lower the seizure threshold.
Monitor ambulation and take appropriate safety precautions.
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
HNBB
Buscopan® [tab]
Antispasmodics
Relieve cramps or spasms of the
stomach,intestines, and bladder
Paroxysmal pain in diseases of the
stomach or intestine, spastic pain &
functional disorders in the biliary & urinary
tracts & female uterine organs (eg
dysmenorrhea).
Rubefaction, allergic reactions w/ exanthema,
thrombocytopenia, leucopenia;
agranulocytosis (in isolated case associated w/ paracetamol), pancytopenia.
Bronchospasm (in predisposed patient).
Myasthenia gravis, megacolon. Should
not be given to patients who have prior sensitivity to
HNBB or paracetamol or any
component of buscopan plus.
Hepatic & renal dysfunction, Gilbert's syndrome. Pregnancy
esp during 1st trimester.
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
DRUG
ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICATION
NURSING RESPONSIBILITY
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery
Galang, Patrick Albert C 3nu05 Drug Study EAMMC - Surgery