cefalo-rahi-liquid
DESCRIPTION
Anato, LCRTRANSCRIPT
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Cerebral Spinal Fluid&
The Meninges
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The Skull
Protection of the Brain
Cranial Meninges
Cerebrospinal Fluid
Blood-Brain Barrier
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1. Dura Mater - Composed of two layers:a) Periosteal – outer layer, attaches to bone.
b) Meningeal – inner layer, closer to brain.
Cranial Meninges - 3 layer protective membrane
Two layers fused, except to enclose the dural sinuses
3. Pia Mater - delicate, follows convolutions.
2. Arachnoid Layer - ‘spider’ web like.
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Subdural space
Potential space between dura and arachnoid mater.
Cranial Meningeal Spaces
Epidural space
Potential space superior to dura.
Subarachnoid space
Filled with CSF
Contains the blood vessels supplying brain.
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The Sinuses
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Roles of CSF:
Cerebrospinal Fluid (CSF)
* CSF formed in the choroid plexuses in ventricles of brain
1. Cushions and insulates delicate nervous tissue.
2. Gives Buoyancy to the brain (“floats” in CSF).
3. Exchange of gases (O2 and CO2), nutrients and wastes.
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Prevents most blood-borne toxins from entering the brain but not an absolute barrier.
Blood Brain Barrier (BBB)
Nutrients such as O2, and glucose can pass. Plus CO2, alcohol, nicotine, and anesthetics.
Dopamine? L-Dopa?
A restrictive barrier around blood vessels in the brain (created by astrocytes).