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Page 1: Cell Division

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Page 2: Cell Division

What is cell ?

Cells are the basic units of all living things.

Cells make up bones, muscles, skin, and blood.

Cells make up leaves, roots, stems, and flowers.

As the organism grows, the cells must reproduce.

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Page 3: Cell Division

Cells

Cells are the structural and functional units of all living organisms. They are of two types:

Unicellular.

Multicellular.

Functions of cell….

Nutrients to Energy..

Each cell having its own set of instruction.

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Eukaryotic cell division..

Eukaryotes must divide their nucleus (and other organelles such as mitochondria) in preparation for cell division (mitosis or meiosis)

Before the nucleus divides the genetic material replicates (duplicates).

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Page 5: Cell Division

Prokaryotic cell division.

Prokaryotes have no nucleus.

They have a single circular chromosome.

Prokaryotes simply divide their cells in two by binary fission.

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Some of important Definitions..

Spindle Fiber -One of a network of filaments that extend inward from the poles of a dividing cell, forming a spindle-shaped figure.

Centromere -The most condensed and constricted region of a chromosome, to which the spindle fiber is attached during mitosis.

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Definition.. Chromatin -A complex of nucleic acids and proteins,

primarily histones, in the cell nucleus that stains readily with basic dyes and condenses to form chromosomes during cell division.

Chromatid -Either of the two daughter strands of a replicated chromosome that are joined by a single centromere and separate during cell division to become individual chromosomes.

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Definition..

Chromosome -thread-like, gene-carrying bodies in the nucleus of a cell. Chromosomes are composed primarily of DNA and protein. They are visible only under magnification during certain stages of cell division. Humans have 46 chromosomes in each somatic cell and 23 in each sex cell.

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Definition..

Equatorial plane -The plane that contains all of the centromeres and their spindle attachments during metaphase of mitosis.

kinetochore fibers -specialized regions in the centromeres of chromosomes.

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Page 11: Cell Division

Cell Cycle.. The cell cycle is the event that makes new cells, by

cell division, through six processes. They are;

interphase,

mitosis(prophase),

mitosis(metaphase),

mitosis(anaphase),

mitosis(telophase), and

cytokinesis

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Page 12: Cell Division

Interphase.

During Interphase cell replicates its nuclear DNA, ensuring that when does it divide at the end of mitotic phase, each of the newly created daughter cells will contain a full set of gene.

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Mitosis..

Mitosis is the mechanism that allows the nuclei of

cells to split and provide each daughter cell with a

complete set of chromosomes during cellular

division. This, coupled with cytokinesis (division of

the cytoplasm), occurs in all multicellular plants

and animals to permit growth of the organism.

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Page 15: Cell Division

Interphase..

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Prophase..

During this first mitotic stage, the nucleolus fades and

chromatin (replicated DNA and associated proteins)

condenses into chromosomes.

Each replicated chromosome comprises two

chromatids, both with the same genetic information.

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Page 17: Cell Division

Prophase..

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Prophase: Animal and plant cell

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Metaphase..

NEXT, THE NUCLEAR ENVELOPE BREAKS DOWN, AND A

LARGE PROTEIN NETWORK, CALLED THE SPINDLE, ATTACHES TO EACH SISTER CHROMATID. THE

CHROMOSOMES ARE NOW ALIGNED PERPENDICULAR TO

THE SPINDLE IN A PROCESS CALLED METAPHASE

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Metaphase..

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Metaphase…

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Anaphase.. Anaphase begins as the centromeres of each pair of

chromatids split, effectively doubling the number of chromosomes.

Once separated, sister chromatids, each now an independent chromosome with its own centromere, begin moving apart toward opposite poles of the cell.

The movement is made possible via two mechanisms.

The kinetochore fibers attached to each centromere begin to shorten, pulling the chromosomes toward the poles.

At the same time, the polar microtubules from opposite ends of the cell form cross bridges in the equatorial plane, pushing the poles apart by becoming longer.

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Anaphase…

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Anaphase: Animal and plant cell

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Telophase.. In telophase, the daughter chromosomes arrive at thespindle poles.

After complete separation of the chromosomes thenuclear membrane begins to reform around each groupof chromosomes at the opposite ends of the cell.

When telophase is complete and the new cellmembrane is being formed.

The final steps in telophase involve the initiation ofplasma membrane cleavage between each of the newdaughter cells to ultimately yield two separate cellsduring cytokinesis, the next phase of cell division.

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Telophase and cytokinesis..

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Telophase: Animal and plant cell..

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Cytokinesis..

The final stage in the process of cell division is known as cytokinesis, which usually begins during late anaphase or early telophase (before mitosis ends).

As the nuclear envelope is reforming and the chromosomes are de-condensing.

During this stage the cytoplasm is divided.

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Page 29: Cell Division

Animal Mitosis review

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