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    CellsCells

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    Section 1: Introduction to the CellSection 1: Introduction to the Cell

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    Discovery of Cells

    Discovery of Cells

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    Discovery of Cells

    Discovery of Cells

    Anton van Leeuwenhoek (1675)

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    MicroscopesMicroscopes Magnification

    microscopes power to increase an

    objects apparent size

    Resolution

    microscopes power to show detailclearly

    2000X

    200X

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    LightM

    icroscopeLightM

    icroscope

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    LightM

    icroscopeLightM

    icroscope

    Elodea - Aquatic Plant

    40X 400X

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    Transmission Electron

    Microscope (

    TEM

    )T

    ransmission ElectronM

    icroscope (T

    EM

    )

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    Scanning ElectronM

    icroscope (SEM

    )Scanning ElectronM

    icroscope (SEM

    )

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    TEM

    vs. SEMT

    EM

    vs. SEM

    Virusesleaving a

    cell

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    The Cell

    Theory

    The Cell

    Theory

    Who developed the cell theory?

    Matthias Schleiden (1838)

    concluded that all plants are

    composed of cells

    Theodor Schwann (1839)

    concluded that all animals arecomposed of cells

    Rudolph Virchow (1855)

    determined that cells come only

    from other cells

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    The Cell

    Theory

    The Cell

    Theory

    So what is the cell theory?

    1. All living things are composed of one

    or more cells.

    2. Cells are organisms basic units of

    structure and function.

    3. Cells come only from existing cells.

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    Functions of LifeF

    unctions of Life

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    Functions of LifeF

    unctions of Life

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    CellD

    iversityCellD

    iversity Size

    Shape

    Internal Organization

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    Cell DiversityCell Diversity--SizeSize

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    Cells diversityCells diversity

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    Cell DiversityCell Diversity-- SizeSize

    6 inches long, 5 inches wide, 3 pounds

    Smallest Cells:

    Longest Cells:

    Ostrich Egg

    Biggest Cells:

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    Cells and SizesCells and Sizes Magnification =

    size of image

    divided by thesize of the

    specimen

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    CellD

    iversityCellD

    iversity-- ShapeShape Cells differ widely in shape.

    Most cells are roughly

    cuboidal or spherical.

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    CellsCells

    DifferentiateDifferentiate

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    So what do we already KNOW?So what do we already KNOW? Cell Theory

    Functions of Life

    Cell Diversity

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    Limiting Cell SizeLimiting Cell Size

    SA = 6 mm2

    SA = 24 mm2

    SA = 96 mm2

    V = 1 mm3

    V = 8 mm3

    V = 64 mm3

    SA/V = 6:1

    SA/V = 3:1

    SA/V = 1.5:1

    V increases faster than SA

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    Stem CellStem Cell

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    Where do you stand in the debateabout the nature of stem cell

    research? How do you feel about the

    source of pluripotent stem cells

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    2.2

    Prokaryotic Cells2

    .2

    Prokaryotic Cells

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    2.2.1

    2.2.2

    Prokaryotic Cell

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    Prokaryotic CellProkaryotic Cell

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    Prokaryotic Cells divide by binaryProkaryotic Cells divide by binary

    fissionfission2.2.4

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    2.3 Eukaryotic Cells2

    .3 Eukaryotic Cells

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    The Parts of the Cell

    The Parts of the Cell

    Each living cell carries out the tasks of taking

    food, transforming food into energy, getting rid of

    wastes, and reproducing. Most eukaryotic cells have three main

    components:

    Cell Membrane

    Cytoskeleton

    Nucleus

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    Animal CellAnimal Cell

    2.3.1

    2.3.2

    Now let

    Annotate this

    picture with allthe functions of

    each structure

    named

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    Plant CellPlant Cell

    Now let

    Annotate this

    picture with all

    the functions ofeach structure

    named

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    LiverLiver

    CellCell

    2.3.3

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    Structure andF

    unction of OrganellesStructure andF

    unction of Organelles The Structure and Function of the following

    organelles will be discussed:

    Cell Membrane Nucleus

    Cell Wall

    Cytoplasm

    Cytoskeleton

    Ribosomes

    Endoplasmic Reticulum

    Golgi Apparatus

    Mitochondria Lysosomes

    Peroxisomes

    Cilia and Flagella

    Basal Bodies

    Centrioles

    Vacuoles

    Plastids

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    CellM

    embraneCellM

    embrane Structure: phospholipid

    bilayer with proteins thatfunction as channels,markers, and receptors-also contains cholesterolwhich provides rigidity

    Function: selectively

    permeable boundarybetween the cell andthe externalenvironment

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    NucleusNucleus Structure: the nucleus is a

    sphere that contains

    another sphere called anucleolus

    Function: -storage center

    of cells DNA

    -manages cell functions

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    Cell WallCell Wall Structure: rigid wall made

    up of cellulose, proteins,

    and carbohydrates Function: boundary

    around the plant cell

    outside of the cell

    membrane that providesstructure and support

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    CytoplasmCytoplasm Structure: gelatin-like fluid that lies inside the cell

    membrane

    Function: -contains salts, minerals and organicmolecules

    -surrounds the organelles

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    CytoskeletonCytoskeleton Structure: a network of

    thin, fibrous elements

    made up of microtubules(hollow tubes) and

    microfilaments (threads

    made out of actin)

    Function: -acts as asupport system for

    organelles

    -maintains cell shape

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    R

    ibosomesR

    ibosomes Structure: consist of two

    subunits made of protein

    and RNA Function: location of

    protein synthesis

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    EndoplasmicR

    eticulumEndoplasmicR

    eticulum Structure: a system of membranous tubules and

    sacs

    Function: intercellular highway (a path alongwhich molecules move from one part of the cell to

    another)

    Two types:

    Rough Endoplasmic Reticulum

    Smooth Endoplasmic Reticulum

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    R

    ough EndoplasmicR

    eticulumR

    ough EndoplasmicR

    eticulum Rough Endoplasmic

    Reticulum (rER):

    prominent in cells thatmake large amounts of

    proteins to be exported

    from the cell or inserted

    into the cell membrane Covered with

    ribosomes

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    Smooth EndoplasmicR

    eticulumSmooth EndoplasmicR

    eticulum Smooth Endoplasmic

    Reticulum (sER): involved

    in the synthesis of lipidsand breakdown of toxic

    substances

    Not covered with

    ribosomes

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    G

    olgi ApparatusG

    olgi Apparatus Structure: stacked flat

    sacs

    Function: receivesproteins from the rER and

    distributes them to other

    organelles or out of the

    cell(receiving, processing,

    packaging, and shipping)

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    M

    itochondriaM

    itochondria Structure: folded

    membrane within an outer

    membrane The folds of the inner

    membrane are called

    cristae

    Function: -convertsenergy stored in food into

    usable energy for work

    cellular respiration

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    PeroxisomesPeroxisomes

    Structure: spherical

    organelles that contain

    enzymes within singlemembranes

    Function: Degrade

    hydrogen peroxide, a

    toxic compound that canbe produced during

    metabolism.

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    Cilia and FlagellaCilia and Flagella

    Structure: hair-like organelles that extend from the

    surface of cells

    When they are present in large numbers on acell they are called cilia

    When they are less numerous and longer they

    are called flagella

    Both organelles are composed of nine pairs ofmicrotubules arranged around a central pair.

    Function: cell motility

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    Cillia and FlagellaCillia and Flagella

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    Basal BodiesBasal Bodies

    The microtubule assembly of a cilium or flagellum

    is anchored in the cell by a basal body.

    Structurally identical to a centriole

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    CentriolesCentrioles

    Structure:

    composed of nine

    sets of tripletmicrotubules

    arranged in a ring

    Exist in pairs

    Function:centrioles play a

    major role in cell

    division (mitosis)

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    VacuolesVacuoles

    Structure: a sac of fluid

    surrounded by a

    membrane Very large in plants

    Function: used for

    temporary storage of

    wastes, nutrients, andwater

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    PlastidsPlastids

    There are three types of plastids in plant cells:

    Chloroplasts (discussed on next slide)

    Chromoplasts: synthesize and store pigments Leucoplasts: store food such as starches,

    proteins, and lipids

    Chromoplasts

    Red Pepper

    Flower

    Leucoplasts

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    ChloroplastsChloroplasts

    Structure: stackedsacs (thylakoids) thatcontain chlorophyll

    surrounded by adouble membrane

    Function:photosynthesis

    (conversion of lightenergy to chemicalenergy stored in thebonds of glucose)

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    Secretory PathwaySecretory Pathway

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    Secretory PathwaySecretory Pathway

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    The following is a list of tissues that have specialized functions

    and demonstrate corresponding specialization of subcellular

    structure. Match the tissue with the letter of the cell structures

    and organelles listed to the right that would be abundant inthese cells.

    Tissues Cell Structures

    and Organelles

    1. Enzyme (protein)-secreting A. plasma membranecells of the pancreas B. mitochondria

    2. Insect flight muscles C. Golgi

    apparatus D. chloroplast

    3. Cells lining the respiratory E. ER

    passages F. cillia & flagella4. White blood cells that engulf G. vacuole

    and destroy invading bacteria H. ribosome

    5. Leaf cells in cacti I. lysosome

    J. peroxisomes

    3

    3

    3

    3

    3

    3

    3

    3

    Str ct ral Organi ation of E kar oticStr ct ral Organi ation of E kar otic

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    Structural Organization of EukaryoticStructural Organization of Eukaryotic

    and Prokaryotic Cellsand Prokaryotic Cells

    2.3.4

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    Eukaryotes vs. ProkaryotesEukaryotes vs. Prokaryotes

    Eukaryotes (animals,

    plants, fungi, protists) and

    prokaryotes (bacteria)differ greatly in structure.

    2.3.4

    Pr r t E r t

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    Pr r t E r t

    nucl us? NO (nucl i ) Y S

    r ne- undr nelles? NO Y S ( ny)

    si e 1 - 10Qm 10 - 0Qm

    whenevolved? 3. illionyearsago 1. illionyearsago

    cytoplasm? Y S Y S

    cell membrane? Y S Y S

    cell wall? Some o Plants

    ribosomes? Y S Y S

    NA?Circular

    ree loatingChromosomes inNucleus

    examples BacteriaPlants,Animals, ungi,and

    Protists

    2.3.4

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    Plant Cells vs. Animal CellsPlant Cells vs. Animal Cells

    Animal cells are very similar to

    plant cells except for the

    following major differences: Animal cells do not contain

    chloroplasts

    Animal cells are not

    surrounded by cell walls

    The vacuoles in plants are

    much larger than those of

    animals

    2.3.5

    Microscope Pictures of aMicroscope Pictures of a

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    Microscope Pictures of aMicroscope Pictures of a

    Plant Cell and an Animal CellPlant Cell and an Animal Cell

    ElodeaElodea Human Cheek CellsHuman Cheek Cells

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    Extracellular componentsExtracellular components

    2.3.6

    Hierarchy of Biological OrderHierarchy of Biological Order

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    Hierarchy of Biological OrderHierarchy of Biological Order

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    THE EN

    D!THE EN

    D!