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5-Methoxy-diethyltryptamineThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Page 1 of 5SWGDRUG.org/monographs.htmLatest Revision: 1/8/2015
NH
NCH3
CH3OCH3
Form Chemical Formula Molecular Weight Melting Point (oC)
Base C15H22N2O 246 Not Determined
HCl C15H22N2O. HCl 282 Not Determined
1. GENERAL INFORMATION
IUPAC Name:
CAS#:
Synonyms:
Source:
Appearance:
UVmax(nm):
N,N-diethyl-2-(5-methoxy-1H-indol-3-yl)ethanamine
Not Available
5-Methoxy-DET, 5-MeO-DET
DEA Reference Material Collection
Brown powder
Not Determined
2. CHEMICAL AND PHYSICAL DATA
2.1 CHEMICAL DATA
5-Methoxy-diethyltryptamineThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Page 2 of 5SWGDRUG.org/monographs.htmLatest Revision: 1/8/2015
3. QUALITATIVE DATA
3.1 NUCLEAR MAGNETIC RESONANCE
Sample Preparation: Dilute analyte to ~25 mg/mL inD2O containing TSP for 0 ppm reference and maleicacid as quantitative internal standard.
Instrument: 400 MHz NMR spectrometerParameters: Spectral width: at least containing -3 ppm through 13 ppm
Pulse angle: 90o
Delay between pulses: 45 seconds1H NMR: 5-Methoxy-diethyltryptamine HCl Lot 2DAK-29-05; D2O; 400MHz
8 7 6 5 4 3 2 1 0
0
1
2
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4
5
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9
10
66231111
TMSMaleic Acid
HDO
7.25 7.00
0
0.25
0.50
1111
3.4 3.3 3.2 3.1
62
1.275
6
3.900
3
5-Methoxy-diethyltryptamineThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Page 3 of 5SWGDRUG.org/monographs.htmLatest Revision: 1/8/2015
3.2 GAS CHROMATOGRAPHY/MASS SPECTROMETRY
Sample Preparation: Dilute analyte ~4 mg/mL base extracted into chloroform.
Instrument:Column:Carrier Gas:Temperatures:
Agilent gas chromatograph operated in split mode with MS detector HP-5 MS (or equivalent); 30m x 0.25 mm x 0.25 µmHelium at 1 mL/minInjector: 280oCMSD transfer line: 280oCMS Source: 230oCMS Quad: 150oCOven program:
1) 100oC initial temperature for 1.0 min2) Ramp to 300oC at 12 oC/min3) Hold final temperature for 9.0 min
Injection Parameters: Split Ratio = 20:1, 1 µL injectedMS Parameters: Mass scan range: 30-550 amu
Threshold: 100Tune file: stune.uAcquisition mode: scan
Retention Time: 14.090 minEI Mass Spectrum: 5-Methoxy-diethyltryptamine HCl Lot # 2DAK-29-05
m/z240220200180160140120100806040
[x 1
06 ]In
tens
ity
1
2
3
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5
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303030 3030303030 3030303030 3030303030 30303030
424242 4242424242 4242424242 4242424242 42424242
585858 5858585858 5858585858 5858585858 58585858636363 6363636363 6363636363 6363636363 63636363 777777 7777777777 7777777777 7777777777 77777777
868686 8686868686 8686868686 8686868686 86868686
103
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103 11
711
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711
7
130
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145 160
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EI+
5-Methoxy-diethyltryptamineThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Page 4 of 5SWGDRUG.org/monographs.htmLatest Revision: 1/8/2015
3.3 INFRARED SPECTROSCOPY (FTIR)
Insrument: FTIR with diamond ATR attachment (1 bounce)Scan Parameters: Number of scans: 32
Number of background scans: 32Resolution: 4 cm-1
Sample gain: 8Aperture: 150
FTIR ATR (Diamond, 1 Bounce): 5-Methoxy-diethyltryptamine HCl Lot # 2DAK-29-05
Wavenumber (cm-1)3500 3000 2500 2000 1500
%Tr
ansm
ittan
ce
20
30
40
50
60
70
432432432432432432432432432432432432432432432432432432432432432432
642642642642642642642642642642642642642642642642642642642642642642
700700700700700700700700700700700700700700700700700700700700700700
810810810810810810810810810810810810810810810810810810810810810810
823823823823823823823823823823823823823823823823823823823823823823
92692692692692692692692692692692692692692692692692692692692692692610281028102810281028102810281028102810281028102810281028102810281028102810281028102810281099
109910991099109910991099109910991099109910991099109910991099109910991099109910991099
1178117811781178117811781178117811781178117811781178117811781178117811781178117811781178
1215121512151215121512151215121512151215121512151215121512151215121512151215121512151215
1225122512251225122512251225122512251225122512251225122512251225122512251225122512251225
12401240124012401240124012401240124012401240124012401240124012401240124012401240124012401460
1460146014601460146014601460146014601460146014601460146014601460146014601460146014601491
149114911491149114911491149114911491149114911491149114911491149114911491149114911491
1624162416241624162416241624162416241624162416241624162416241624162416241624162416241624
2596259625962596259625962596259625962596259625962596259625962596259625962596259625962596
2640264026402640264026402640264026402640264026402640264026402640264026402640264026402640
2939293929392939293929392939293929392939293929392939293929392939293929392939293929392939
3184318431843184318431843184318431843184318431843184318431843184318431843184318431843184
Wavenumber (cm-1)1700 1600 1500 1400 1300 1200 1100 1000 900 800 700
%Tr
ansm
ittan
ce
20
30
40
50
60
70
432432432432432432432432432432432432432432432432432432432432432432
642642642642642642642642642642642642642642642642642642642642642642
700700700700700700700700700700700700700700700700700700700700700700
710710710710710710710710710710710710710710710710710710710710710710
810810810810810810810810810810810810810810810810810810810810810810
823823823823823823823823823823823823823823823823823823823823823823
926926926926926926926926926926926926926926926926926926926926926926
1028102810281028102810281028102810281028102810281028102810281028102810281028102810281028
10661066106610661066106610661066106610661066106610661066106610661066106610661066106610661099
109910991099109910991099109910991099109910991099109910991099109910991099109910991099
1178117811781178117811781178117811781178117811781178117811781178117811781178117811781178
1215121512151215121512151215121512151215121512151215121512151215121512151215121512151215
1225122512251225122512251225122512251225122512251225122512251225122512251225122512251225
1240124012401240124012401240124012401240124012401240124012401240124012401240124012401240
1439143914391439143914391439143914391439143914391439143914391439143914391439143914391439
14461446144614461446144614461446144614461446144614461446144614461446144614461446144614461460
1460146014601460146014601460146014601460146014601460146014601460146014601460146014601491
149114911491149114911491149114911491149114911491149114911491149114911491149114911491
1624162416241624162416241624162416241624162416241624162416241624162416241624162416241624
5-Methoxy-diethyltryptamineThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Page 5 of 5SWGDRUG.org/monographs.htmLatest Revision: 1/8/2015
4. ADDITIONAL RESOURCES
No resources identified as of 1/8/15.