ch_16.5_transcription.ppt

8/17/2019 Ch_16.5_Transcription.ppt

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Warm-up….do you Warm-up….do you

remember?remember?1.1. Name the 2 steps of ProteinName the 2 steps of ProteinSynthesisSynthesis

2.2. Where do they take placeWhere do they take place3.3. If the DNA code is AGACCAAIf the DNA code is AGACCAA

!hat ist the m"NA code#!hat ist the m"NA code#


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From Gene toFrom Gene to

Protein IProtein I

TranscriptionTranscription


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$ ranscriptionranscription

$ realistic speedrealistic speed

http://www.youtube.com/watch?v=ztPkv7wc3yUhttp://www.youtube.com/watch?v=ztPkv7wc3yUhttps://www.youtube.com/watch?v=erOP76_qLWAhttps://www.youtube.com/watch?v=erOP76_qLWAhttps://www.youtube.com/watch?v=erOP76_qLWAhttp://www.youtube.com/watch?v=ztPkv7wc3yU


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GenesGenes

$ Se%ments on the DNA Se%ments on the DNA

Genes are separated &y lar%e non'Genes are separated &y lar%e non'

codin% se()ences *+,- of the DNAcodin% se()ences *+,- of the DNAis non codin%'remnants fromis non codin%'remnants from

eol)tion/eol)tion/

$ OneOne %ene codes for%ene codes for oneone proteinprotein


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Steps of ProteinSteps of Protein

SynthesisSynthesis11. Transcription. Transcri

ption0 copyin% the DNA0 copyin% the DNA

into m"NA into m"NA

2. Transation!2. Transation! translatin% m"NAtranslatin% m"NAinto an Amino Acid se()enceinto an Amino Acid se()ence

". Protein Fodin#". Protein Fodi

n#0 Chaperonesself0 Chaperonesself

catalysiscatalysis


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TranscriptionTranscription

$ nyme0nyme0 $%& poymerase$%& poymerase


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Steps of Transcription!Steps of Transcription!

$%& Poymerase$%& Poymerase1.1. separates DNA at the &e%innin% of aseparates DNA at the &e%innin% of aGeneGene

2.2. complementary &ase pairs only onecomplementary &ase pairs only one

strand *template strand/ !ithstrand *template strand/ !ith freefree$%& nuceotides$%& nuceotides

3.3. makes a transcript ofmakes a transcript of one %ene0one %ene0 m-m-

$%& $%& N40 "NA hasN40 "NA has nono Thymine 'T( ))))Thymine 'T( ))))

T isT is replaced &yreplaced &y *raci '*(*raci '*(


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Transcribe the foo+in#Transcribe the foo+in#

Gene into $%& Gene into $%& ,%&!,%&!

&&TG&T&GG &&TG&T&GG

m$%&!m$%&! **&*G&***&*G&*


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,ierences bet+een ,%&,ierences bet+een ,%&

andand $%& $%& 1.1. "NA is only"NA is only / strand/ strand *can*cando)&le strand to form catalyticdo)&le strand to form catalytic

molec)les t'"NA5 r"NA/molec)les t'"NA5 r"NA/2.2. Di6erent s)%ar0Di6erent s)%ar0 $ibose$ibose

instead of Deo7yri&oseinstead of Deo7yri&ose

3.3. "NA )ses"NA )ses *raci '*(*raci '*( in placein placeof hymine */of hymine */


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Preparation forPreparation for

TransationTransation$ m"NA detaches from DNA m"NA detaches from DNA $ m"NA leaes n)cle)s enters cytoplasmm"NA leaes n)cle)s enters cytoplasm

$7ons *non'codin% se%ments inside a7ons *non'codin% se%ments inside a%ene/ are c)t o)t0%ene/ are c)t o)t0 Spicin#Spicin# &y sn"NP&y sn"NP

*sn)rps 8small n)clear*sn)rps 8small n)clear

"i&oN)cleoProteins/"i&oN)cleoProteins/

$ 9eaes n)cle)s %oes to cytoplasm09eaes n)cle)s %oes to cytoplasm0"i&osomes"i&osomes for ranslationfor ranslation

ch_16.5_transcription.ppt

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