chair’s report - university of alberta · letter from the chair dear friends & colleagues!...

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Page 1 Letter from the Chair Dear Friends & Colleagues! This is the Chair’s report before the Summer break! Unbelievable that almost half a year already past, but after a tough winter we can look forward to some time off enjoying the summer. The Edmonton Lab Hub project has been paused and we are awaiting further direction from the government. The transition to Alberta Public Laboratories (APL) has been completed and our new Lab Services entity is now focusing on achieving its first strategic goals. The implementation of ‘Connect Care’ is now entering the training phase. The Super-Users and Physician-Builders have already completed their first training courses and all other staff have now been scheduled for training sessions for the late summer / early fall, i.e. right before Wave 1 of go live in the Edmonton Zone. I sincerely thank you and appreciate your ongoing commitment, time, energy, and tremendous effort to move these large-scale transformative projects forward suc- cessfully! Please join me in congratulating our faculty members who will be promoted for the coming academic year and I welcome our new appointees to the department – see full list of names on page 6. I also would like to acknowledge the re-appointments of three of our Divisional Directors: Dr. Judith Hugh, Dr. Greg Tyrrell, Ms. Lisa Purdy – see page 7. All are entering their second terms as Divisional Directors and other APL leadership roles and I’m grateful for their leadership in their Divisions and programs as the critical engines moving our department forward. Again, the last quarter has been very productive in terms of papers, presentations, new grants, and recognitions achieved by our faculty members – summarized on page 9-16. Please review our Spotlight on Education. In this issue we feature the Medical Laboratory Science (MLS) Program – see page 3-4. The MLS program is the flagship program for this discipline in Canada and has recently undergone external review confirming its exceptional standing in terms of educational innovation and leadership in Medical Laboratory Science. Under the leadership of Ms. Lisa Purdy, the program went through a strategic planning and repositioning process, which was recognized by a significant investment from the Provost special purpose fund allowing the program to now develop new curriculum content for a MSc degree laddering expansion – Way to go Team MLS! Chair’s Report Department Of Laboratory Medicine & Pathology Faculty of Medicine & Dentistry University of Alberta Inside this issue: Spotlight on Education 3-4 Awards & Honours 5 Grants 5 New appointments 6 Promotions 6 Appointment Renewals 7 Residency Programs 8-9 Grad Studies 9 Presentations 9-12 Publications 13-16 DRIvE / Banff Pathology Course 17-20 June 2019 Ms. Lisa Purdy & Ms. Roberta Martindale Department of Lab Medicine & Pathology Alberta Public Laboratories (APL)

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Page 1: Chair’s Report - University of Alberta · Letter from the Chair Dear Friends & Colleagues! This is the Chair’s report before the Summer break! Unbelievable that almost half a

uab.ca/LMP Page 1

Letter from the Chair

Dear Friends & Colleagues! This is the Chair’s report before the Summer break! Unbelievable that almost half a year already past, but after a tough winter we can look forward to some time off enjoying the summer. The Edmonton Lab Hub project has been paused and we are awaiting further direction from the government. The transition to Alberta Public Laboratories (APL) has been completed and our new Lab Services entity is now focusing on achieving its first strategic goals. The implementation of ‘Connect Care’ is now entering the training phase. The Super-Users and Physician-Builders have already completed their first training courses and all other staff have now been scheduled for training sessions for the late summer / early fall, i.e. right before Wave 1 of go live in the Edmonton Zone. I sincerely thank you and appreciate your ongoing commitment, time, energy, and tremendous effort to move these large-scale transformative projects forward suc-cessfully! Please join me in congratulating our faculty members who will be promoted for the coming academic year and I welcome our new appointees to the department – see full list of names on page 6. I also would like to acknowledge the re-appointments of three of our Divisional Directors: Dr. Judith Hugh, Dr. Greg Tyrrell, Ms. Lisa Purdy – see page 7. All are entering their second terms as Divisional Directors and other APL leadership roles and I’m grateful for their leadership in their Divisions and programs as the critical engines moving our department forward. Again, the last quarter has been very productive in terms of papers, presentations, new grants, and recognitions achieved by our faculty members – summarized on page 9-16. Please review our Spotlight on Education. In this issue we feature the Medical Laboratory Science (MLS) Program – see page 3-4. The MLS program is the flagship program for this discipline in Canada and has recently undergone external review confirming its exceptional standing in terms of educational innovation and leadership in Medical Laboratory Science. Under the leadership of Ms. Lisa Purdy, the program went through a strategic planning and repositioning process, which was recognized by a significant investment from the Provost special purpose fund allowing the program to now develop new curriculum content for a MSc degree laddering expansion – Way to go Team MLS!

Chair’s Report Department Of Laboratory Medicine & Pathology

Faculty of Medicine & Dentistry

University of Alberta

Inside this issue:

Spotlight on Education 3-4

Awards & Honours 5

Grants 5

New appointments 6

Promotions 6

Appointment Renewals 7

Residency Programs 8-9

Grad Studies 9

Presentations 9-12

Publications 13-16

DRIvE / Banff

Pathology Course

17-20

June 2019

Ms. Lisa Purdy & Ms. Roberta Martindale

Department of Lab Medicine & Pathology Alberta Public Laboratories (APL)

Page 2: Chair’s Report - University of Alberta · Letter from the Chair Dear Friends & Colleagues! This is the Chair’s report before the Summer break! Unbelievable that almost half a

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Registration is open for the 2019 Banff Pathology Course, which will be held on September 05. - 07. 2019 – the topic is Breast Pathology. The annual APL resi-dents’ retreat for all Edmonton and Calgary AP and GP residents will also be taking place in conjunction with the Banff course. I hope to see many of you in Banff!

Sincerely, Dr. Michael Mengel, MD Professor and Chair Department of Laboratory Medicine & Pathology, University of Alberta North Sector Medical Director, Alberta Public Laboratories

Letter from the Chair (cont’d)

The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

If you fail, never give up because F.A.I.L. means “First Attempt In Learning” End is not the end. In fact E.N.D. means “Effort Never Dies” If you get NO as an answer, remember N.O. means “Next Opportunity”

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

Spotlight on Education

Medical Laboratory Science

Ms. Lisa Purdy, Divisional Director and

Ms. Roberta Martindale, Program Coordinator

Medical Laboratory Science overhaul brings rich, experiential learning opportunities

Hands-on training crucial to master emerging technologies, says director With big data, artificial intelligence and precision health making strides in medical research and practice, the University of Alberta’s Medical Laboratory Science program is in the midst of major changes to ensure the professionals coming out of its program are ready to hit the ground running. The four-year undergraduate degree, which celebrated its 60th anniversary in 2018, sees an annual intake of 29 students seeking both certification as a medical laboratory technologist and the enhanced theoretical knowledge that comes with hav-ing earned a degree. It’s the only degree- granting program of its kind in Western Canada, and director Lisa Purdy wants to see it grow. Massive change is ahead in this field. “With the way technology is going, we need to be developing lab professionals who will be change agents, and who can help other health professionals manage the new technology,” she says. To get ahead of the demand, Purdy is creating a new master’s degree in Medical Laboratory Science. In the process of work-ing its way through university governance, the graduate program is so ahead of the curve, it will “create a professional that Alberta Health Services may not yet even have a job description for.” Launching a master’s program necessitated an overhaul of the undergraduate degree as well, a process Purdy welcomes as a chance to analyze and shift the desired program outcomes to better reflect current U of A focuses such as ethics and com-munity outreach. An example of this is the recent elimination of the upper quota on the number of Indigenous students admitted to the Medical Laboratory Science program. “We need to be socially accountable as health professionals; we need to train our students to be more culturally aware”, says Purdy. The technical program’s focus has always been on making sure students are prepared to meet national certification criteria. Purdy says that won’t change, but the best health professionals of the future will also be intent on serving, giving back and engaging in the community. A professionalism course will be offered throughout the program’s three years, with opportuni-ties to explore what being an ethical and engaged member of the community looks like. Purdy is also exploring a future op-tion for a rural rotation to address underserved community needs.

Continued ...

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

It’s in the final undergraduate year that the most sweeping curriculum changes appear, addressing the emerging technolo-gies learners need to master. A series of one-credit courses—offered over three weeks online and one weekend hands-on in the lab—focus on advanced training in processes such as mass spectrometry and flow cytometry, neither of which are new technologies but are continually being called into action in new and different ways. “We have been teaching mass spec for years,” clarifies Purdy, “but most of it has been didactic. Now we want our students to get their hands on those instru-ments and become really proficient at using them, to address the growing need in clinical service.” Because the modules are mostly online, they’ll be accessible not only to students in the undergraduate program, but also—in partnership with the Faculty of Extension—to professionals looking to advance their career development. This shift to online learning and making learning more accessible to non-degree students is brand new for the program and a necessity to ensure practising technologists keep up their professional development. The proposed MSc in Laboratory Medicine & Pathology with Specialization in Medical Laboratory Science—which Purdy hopes to see launch in the fall of 2022—goes even further to ensure students enter their profession ready to embrace its fast pace of change. Purdy has proposed for the MSc four areas of specialization that reflect current and future needs: Bio-informatics & Molecular Diagnostics; Laboratory Leadership; Research & Development and Laboratory Utilization & Ap-plied Statistics.

Medical Laboratory Science (cont’d …)

(Courtesy of Sasha Roeder Mah, from The Bridge)

Front row (L to R): Kimberlea Thompson, Valentin Villatoro, Chris Ward, Anthony Ralston Middle row (L to R): Roberta Martindale, Anna Nevesinjac, Kristi Lew, Lisa Purdy, Cheryl Titus Back row: (L to R): Zara Ahmed, Jelena Holovati, Monika Keelan, Karen Matejka Missing: Amanda VanSpronsen, Ben Bablitz

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

Awards & Honours Dr. Jason Acker received the “GSA Graduate Student Supervisory Award,” University of Alberta, Graduate Stu-dents’ Association, Mar 22, 2019. This award is present-ed by the Graduate Students’ Association for “excellence in mentoring and supervision, leadership amongst their peers in engaging graduate students; con-tribution to graduate student professional development; and overall commitment to the success of graduate stu-dents in their program”. Dr. Linda Chui was awarded the “MP 2019 Staff Recog-

nition Award for Excellence in Supporting Students”.

Dr. Janet Elliott has been elected as “Fellow of the Ameri-can Institute for Medical and Biological Engineering”, a distinc-tion reserved for the top two per cent of medical and biological engineers. (March 25, 2019, Washington, DC). Ms. Danielle Lee was awarded the CAP-ACP (Canadian Association of Pathologists) “President Award for 2019.” This award is presented by the President for long and sustained service of an exceptional order to the CAP-ACP in whatever capacity, by an individual, mem-ber or non-member, a physician or non-physician. She will be presented this award on June 25, 2019 in Niagara Falls at the annual CAP-ACP Conference. Dr. Harry Vinters was named to Google Scholars list of “Highly Cited” scientists of the past 120 years---h-index 100 + (Vinters cited as #1374 on the list). Dr. Lori West received “The Inaugural Janet Rossant Lec-tureship”, 2019 Massey Grand Rounds (MGR) Symposi-um on “Healthy Ageing”, University of Toronto, Ontar-io. March 2019

Grants

Dr. Ben Adam received a grant from the Canada Foun-dation for Innovation/Alberta Economic Development and Trade. Amount: $150,000. Term: 04/2019-03/2020. Role: Principal Investigator. Project title: “Molecular injury and repair assessment in ex vivo perfused solid organ transplants” Dr. Andrei Drabovich was nominated PI, Movember Rising Star in Prostate Cancer Research grant "Bridging genomics and proteomics to identify protein biomarkers for stratifica-tion of prostate cancer aggressiveness”, Prostate Cancer Canada, application # RS2015-01. Total amount: $117,782 CAD. November 1, 2018 – October 31, 2019. Dr. Josh Raizman received a Covenant Health Research Centre grant for 2018-2019 in the amount of $2348 for the research project entitled “Development of Laboratory Re-porting Guidelines for Hydroxycobalamin Interference in Patients Pulled from House Fires”. Dr. Lori West received the following grants: 1. Luminex bed-based ABO antibody assay: “Defining

normal and seeking clinical opportunities”. West LJ (PI), Cairo C (Co-PI), Canadian Glycomics Network, Al-berta Partnership Projects RFP. $100,000 Total Fund-ing: April 2019-March 2020.

2. “Preparing for combined stem cell and solid organ transplants: Learning from hematopoietic mixed Chimeras”. West LJ (PI), The Canadian Donation and Transplantation Research Program, National Child Health Transplant Team Grant Award, $6500 Total Funding; March 2019.

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

New Appointments

Dr. Banu Sis has served as a grant reviewer / panel member at 2019 Women and Children’s Health Re-search Institute (WCHRI) Innovation Grants Biomedical Advisory Committee. The Department has appointed our CBD (Competency Based by Design Medical Education) Leads:

Dr. Kerri Chung, Anatomical & General Pathology

Dr. Kathleen Wong, Hematological Pathology

Dr. Nathan Zelyas, Medical Microbiology The Department welcomes:

Dr. Kimberly Wood - Clinical Lecturer / Staff Pathologist, Misericordia Community Hospital & DynaLIFE

Dr. Hanan Armanious - Assistant Clinical Professor /Staff Pathologist, Red Deer Regional Hospi-

tal Centre Dr. Nathan Zelyas - Clinical Lecturer / Medical Microbiologist, University of Alberta Hospital

Mr. Wenjun Liu - Clinical Lecturer, Pathologists’ Assistant, Queen Elizabeth II Hospital, Grande

Prairie

Welcome to Dr. Nathan Zelyas Dr. Zelyas is the new Program Direc-tor, Medical Microbiology Residency Program. Dr. Zelyas was a resident in the program from 2011 – 2016 and began working as a Medical Virologist at Provincial Lab upon graduating in 2016.

Promotions

Please join us in congratulating the following on their promotions effective July 1st

Dr. Hongquan Zhang to Associate Professor

Dr. Melanie Bodnar to Associate Clinical Professor

Dr. Christopher Walker to Associate Clinical Professor

Dr. Wayne Ramsey to Associate Clinical Professor

Dr. Terence Agbor to Assistant Clinical Professor

Dr. Sumit Das to Assistant Clinical Professor

Ms. Danielle Lee to Assistant Clinical Professor

Dr. Heidi Paulin to Assistant Clinical Professor

Dr. Laura Schmitt to Assistant Clinical Professor

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

Appointment Renewals

Dr. Gregory Tyrrell, APL Section Chief Microbiology North Sector and Divisional Director Diagnostic and Applied Microbiology, De-partment of Laboratory Medicine & Pathology, Faculty of Medicine & Dentistry, University of Alberta.

Dr. Greg Tyrrell served for the last five years as Section Chief Micro-biology for the Edmonton Zone and as Divisional Director Diagnos-tic and Applied Microbiology, Department of Laboratory Medicine & Pathology, Faculty of Medicine & Dentistry, University of Alberta. In his dual role Dr. Tyrrell focused on integrating acute care Infectious disease diagnostics with the Provincial Laboratory for Public Health and our microbiology colleagues at DynaLIFE Diagnostics, while simultaneously facilitating the transition and integration of the Medical and Clinical microbiology training programs in our department. Dr. Tyrrell has agreed to renew his term for this dual role for the next three years.

Dr. Judith Hugh, APL Site Chief University of Alberta Hospital and Divisional Director Anatomical Pathology, Department of Laboratory Medicine & Pathology, Faculty of Medicine & Dentistry, University of Alberta.

Dr. Judith Hugh served the last five years as Site Chief at the Universi-ty of Alberta Hospital and as Divisional Director Anatomical Patholo-gy, Department of Laboratory Medicine & Pathology, Faculty of Med-icine & Dentistry, University of Alberta. In her dual role Dr. Hugh has made major contributions to recruitment, quality clinical service deliv-ery and facilitation of our training programs at the University of Alber-ta Hospital site. Dr. Hugh has agreed to renew her term for this dual role for the next three years.

Ms. Lisa Purdy, Director for the Medical Laboratory Science (MLS) Program. Ms. Purdy has served in this role for the last five years and has led the program together with the MLS faculty and staff through suc-cessful accreditation reviews, a strategic planning exercise, and to securing additional funding form the Provost Office for further developing the scope of the MLS program. Ms. Purdy’s commitment to the MLS program, our department and her exceptional leadership has advanced our Vision and Mis-sion for excellence in education. Ms. Purdy has agreed to renew her term for this role for the next five years.

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

Medical Microbiology Residency Program

L to R: Luiz Lisboa, Laura Burnes, Xiaofeng Ding, Hong Yuan Zhou, Sean Ling, Heather Glassman, Peet van der Walt, Ifueko Adeghe, Clayton MacDonald

The Medical Microbiology Residents said farewell to Dr. Hong Yuan Zhou in April. Dr. Zhou was the Program Director for the Medical Microbiology Residency program from March 2018 to April 2019. Dr. Zhou moved to Calgary to be closer to her family. She will continue on in her role as Medical Virologist at Provincial Lab Southern Alberta (PLSA) and as-sures everyone that she is just an email away.

*******************************************************************************************

The Medical Microbiology Residency Program hosted this years LMP Resident Retreat on April 23. Residents from AP, GP, Hematopathology and Med Micro participated in the event. Sessions included a Clinician’s Perspective on Alberta Public Labs by Dr. Dilini Vethanayagam, Transition to Practice Tips by Ryan Smith from MD Financial Management, and a presentation on the new PARA contract by Rob Key from the Professional Association of Resident Physicians of Alber-ta. The afternoon included a resident wellness event hosted by the microbiology residents at The Cat Café on Whyte.

Page 9: Chair’s Report - University of Alberta · Letter from the Chair Dear Friends & Colleagues! This is the Chair’s report before the Summer break! Unbelievable that almost half a

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

Graduate Studies

Congratulations to Nicholas Wawryk who has been awarded an Alexander Graham Bell Canada Graduate Scholarship – Master’s (NSERC CGS-M).

Hematopathology

Residency Program

Dr. Brian Wong has been nominated for the “Dr. T A Kasper Resident Excellence Scholarship”. The value of the award is $4,000 and is awarded to a Medicine resident with superior academic achievement special-izing in any of the three disciplines of Pathology (Anatomical, General Pathology or Hematopatholo-gy). Selection based on academic standing as demon-strated by excellence on the residency exam.

Summer Studentship

Stipend Recipients

Ruqaya Jasim (supervisor: Dr. Ben Adam)

Teresa Kumblathan (supervisor: Dr. Xing-Fang Li) Regina Mendoza (supervisor: Dr. Andrei Drabovich)

Presentations

Dr. Jason Acker: Presentations 1. Acker, J.P. “Cryobiology 101: How a knowledge of cryo-

preservation is critical to the development of cell therapeu-tics”. Canadian Donation and Transplant Research Program 2019 Training Webinar Series, March 11, 2019. Invited

2. Acker, J.P. “Taking good business ideas out of the lab…. the 4 P’s that will help you commercialize your research”. SMO 686: Entrepreneurial Strategizing, Alberta School of Business, University of Alberta, Feb 25, 2019.

3. Extreme Cryo 2019: Frozen Fertility!, Saskatoon, Saskatchewan, Feb 2, 2019.

Acker, J.P. and Hagedorn, M. “Enabling the Cryopreservation of embryos from aquatic species using ice recrystallization inhibitors”.

Sajja, A., Acker, J.P., Turner, T. and Ben, R. “Improving Long-Term Storage Conditions of Peripheral Blood Mononuclear Cells Using Small Molecule Ice Recrystallization Inhibitors to Mitigate Ice-Recrystallization Induced Cryoinjury”.

Lautner, L., Acker, J.P., Nagendran, J. “The Use of Ice Recrystallization Inhibitors in the Cryo-preservation of Lungs”.

William, N., Acker, J.P. and Ben, R. “Mitigating Post-Thaw Cellular and Structural Injury in Liver Tissue Sections Using Small Molecule Ice Recrystalli-zation Inhibitors”.

Dr. Ben Adam: 1. “Improved Risk Stratification with Gene Expression Testing

in Gastrointestinal Stromal Tumors” [platform presenta-tion]. March 19, 2019. USCAP Annual Meeting, Na-tional Harbor, MD.

2. “Gene Expression in Formalin-Fixed Paraffin-Embedded Lung Transplant Biopsies: Correlation Between Molecular and Histologic Phenotypes” [platform presentation]. April 4, 2019. ISHLT Annual Meeting, Orlando, FL.

3. “The Molecular Microscope - What Has It Told Us About Transplant Histology?” [invited lecture]. April 11, 2019. World Congress of Nephrology, Melbourne, Austral-ia.

Abstracts 1. USCAP Annual Meeting, National Harbor, MD,

March 16-21, 2019.

Adam BA, Boils CL, Bu L, Renaudin K, Mengel M. “The molecular pathology of immune checkpoint in-hibitor-induced acute kidney injury: Overlap between native and transplant phenotypes” [abstract]. Mod Pathol. 2019;32(S2):1581.

Du K, Rotich S, Mengel M, Adam BA. “Correlation between gene expression and histology in lung transplant biopsies: a retrospective single-center study” [abstract]. Mod Pathol. 2019;32(S2):1803.

Adam BA, Nowak K, Formenti K, Izevbaye I. “Improved risk stratification with gene expression testing in gastrointestinal stromal tumors” [abstract]. Mod Pathol. 2019;32(S2):578.

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

Dr. Ben Adam: (cont’d) 2. ISHLT Annual Meeting, Orlando, FL, April 3-6, 2019.

Adam BA, Du K, Rotich S, Mengel M. “Gene ex-pression in formalin-fixed paraffin-embedded lung trans-plant biopsies: Correlation between molecular and histologic phenotypes” [abstract]. J Heart Lung Transplant. 2019;38(4):S56.

Rotich S, Herbers N, Hatami S, Nagendran J, Mengel M, Freed DH, Adam BA. “Gene expression in ex vivo perfused porcine hearts: Identification of a molec-ular injury-repair response” [abstract]. J Heart Lung Transplant. 2019;38(4):S183-S184.

Buchko MT, Himmat S, Stewart CJ, Hatami S, Dromparis P, Adam BA, Freed DH, Nagendran J. “Continuous hemodialysis during ex vivo lung perfusion allows for improved maintenance of perfusate composition, without compromising functional performance”. J Heart Lung Transplant. 2019;38(4):S237-238.

Dr. Linda Chui Abstracts 1. AMMI-CACMID (April 3-6, 2019), Ottawa.

Byron Berenger, Linda Chui, Christina Ferrato, Tracie Lloyd, Dylan Pillai. “Evaluation of Five Com-mercial Nucleic Acid Tests for Bacterial Gastroenteritis in Alberta, Canada”.

Wilson W. Chan, Dylan Pillai, Linda Chui, Byron Berenger. “Comparison of Culture-Based Method for the Detection of Shiga toxin-producing E. coli”.

Michael Bording-Jorgensen, Brendon Parsons, Jonas Szelewicki, Colin Lloyd, Linda Chui. “Molecular Detection Of Non-O157 Shiga Toxin-Producing Escherichia coli (STEC) Directly From Stool Using Real-time Multiplex PCR Assays”.

Linda Chui, Christina Ferrato, Vincent Li. “Surveillance of Methicillin-Resistant Staphylococccus au-reus (MRSA) from Blood Culture Isolates in Alberta, 2013-2017”.

2. The Pediatric Academic Societies (PAS) Meeting (April 24-May1), Baltimore, MD. USA

Gillian A.M. Tarr, Xiao-Li Pang, Bonita Lee, Lin-da Chui, Samina Ali,, Shannon MacDonald, Ste-phen B. Freedman on behalf of the Alberta Pro-vincial Pediatric EnTeric Infection TEam (APPETITE). “Norovirus Emergency Department Vis-its and Inpatient Hospitalizations”.

Gillian A.M. Tarr, Chu Yang Lin, Ben Vander-meer, Diane Lorenzetti, Phillip I. Tarr, Linda Chui, Lisa Hartling, Stephen B. Freedman on behalf of the Alberta Provincial Pediatric EnTer-ic Infection TEam (APPETITE). “Diagnostic Test Accuracy of Commercial Tests for Detection of Shiga Toxin-Producing Escherichia coli (STEC): A Systematic Review and Meta-Analysis”.

Jianling Xie, Gillian A.M. Tarr, Samina Ali, Linda Chui, Xiao-Li Pang, Bonita Lee, Otto G. Vander-kooi, Phillip I. Tarr, Ran Zhuo, Brendon Par-sons, Byron Berenger, Kelly Kim, Stephen B. Freedman MDCM, MSc11 on behalf of the Al-berta Provincial Pediatric EnTeric Infection TEam (APPETITE) and Pediatric Emergency Research Canada (PERC). “Feces Visibility on Rec-tal Swabs Used to Detect Enteropathogens: A Prospective Cohort Study”.

Kellner T, Parsons B, Chui L, Berenger BM, Xie J, Burnham CA, Tarr PI, Lee BE, Nettel-Aguirre A, Szelewicki J, Vanderkooi OG, Pang XL, Zel-yas N, Freedman SB; Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE). “Comparative Evaluation of Enteric Bacterial Culture and a Molecular Multiplex Syndromic Panel in Children with Acute Gastroenteritis”.

Gillian A.M. Tarr, Ran Zhuo, Brendon Parsons, Xiao-Li Pang, Bonita Lee, Linda Chui, Samina Ali, Stephen B. Freedman. “Natural History of Astrovirus- and Sapovirus-associated Gastroenteritis in Children Visiting the Emergency Department”.

Dr. Matthew Croxen: Ranasinghe, R., Short, K., Croxen, M., Azana, R., Brod-kin, E., and Hoang, L. “Use of whole genome sequencing data to detect and investigate a community-based outbreak of carbapenemase-producing Escherichia coli”. CACMID 2019. April 3 – 6, 2019, Ottawa, Ontario. Poster

Dr. Tanis Dingle: Abstracts 1. DRIvE Days, Edmonton, AB, April 12-13, 2019.

Van der Walt, P. and Dingle, T.C. “A review of Pneumocystis jirovecii microscopy in Northern Alberta”.

Feng, L., Jansen, B. and Dingle, T.C. “Evaluation of MALDI-TOF MS for identification of dermatophytes and aerobic actinomycetes”

Presentations (cont’d)

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

Dr. Tanis Dingle (cont’d): 2. AMMI-CACMID 2019, Ottawa, ON, Apr 3-6,

2019.

Bharat, A., Alexander, D.C., Dingle, T.C., Du-fresne, P.J., Hoang, L.M., Kus, J.V., Gade, L., Litvintseva, A.P., McGeer, A., Mulvey, M.R. “Candida auris in Canada, 2012-Feb 2019”.

German, G.J., et al. “Antimicrobial resistance non-susceptibility rates for Escherichia coli isolates from Ca-nadian hospitals (2016 vs 2017) using a standardized antibiogram collection protocol”.

Garcia-Jeldes, F., et al. “Candida auris prevalence in Canadian acute care hospitals, 2018”.

Van der Walt, P. and Dingle, T.C. “A review of Pneumocystis jirovecii microscopy in Northern Alberta”.

Dr. Andrei Drabovich 1. Invited speaker: “Proteomic and Proteogenomic Approach-

es to the Identification of Prostate Cancer Biomarkers in Seminal Plasma” Alberta Prostate Cancer Research Initiative (APCaRI 2019) Meeting, Red Deer, AB. 2019-05-11.

2. Poster presentation: Junyan Zhang, Andrei Drabo-vich, Keith Jarvi, Andrée Fisher, Sergey Moskovtsev and Clifford Librach. “Evaluation of acrosome- and tail-specific proteins ACRV1 and AKAP4 as biomarkers for sperm selection: a potential novel methodology to select rare and best quality sperm”. American Society of Androlo-gy 44th Annual Conference, Chicago, IL, USA. 2019-04-08.

Dr. Steven Drews: Abstracts

1. O'Brien, S., Stramer, S., Proctor, M., Tonnetti, L., Bres, V., Linnen, J., Bernier, F., Delage, G., Gazi-ano, T., Gregoire, Y., Labrie, J., Bigham, M., Hawes, G., Scalia, V., Fearon, M., Drews, S. “Prevalence of Babesia microti in Canadian Blood Donors”. ISBT, Basel Switzerland, June 22-26.

2. Crowcroft, N.S., Schwartz, K.L., Savage, R.D., Chen, C., Johnson, C., Li, Y., Marchand-Austin, A., Bolotin, S., Deeks, S.L., Jamieson, F.B., Drews, S.J., Russell, M.L., Svenson,, L.W., Simmonds, K., Rig-holt, C., Bell, C.A., Mahmud, S.M., Kwong, J.C. “The challenges of assessing pertussis vaccine effectiveness in the field: A Canadian Immunization Research Network Study”. 12th International Symposium on Bordetella, April 9th-12th, 2019 – Brussels, Belgium Bordetella conference.

3. AMMI/CACMID, Ottawa, ON, Canada, April 5, 2019.

German, G., Keenan, R., Arseneau, V., Tsang, R., Petrich, A., Drews, S, “Bordetella pertussis Molec-ular Validation / Verification Using AmpliVue and the BDMax with Open System reagents to allow for timely and cost-effective testing for both routine and out-break demands”.

Susan Stramer, S., Proctor, M.C., Tonnetti, L., Brès, V., Linnen, J.M., Bernier, F., Delage, G., Grégoire, Y., Labrie, J., Bigham, M. Drews, S.J., Hawes, G., O’Brien, S., Scalia, V, Fearon, M, “Surveillance for Babesia in Canadian blood donors using the ultra-sensitive Procleix® Babesia Assay (PBA) and secondary laboratory testing methods: July-October 2018”.

Drs. Janet Elliott & Locksley McGann: Presentations 1. Oral presentations at “Extreme Cryo: Frozen Fertili-

ty”, University of Saskatchewan, February 2–3, 2019.

Nasim Eskandari, Leah A. Marquez-Curtis, Locksley E. McGann, Janet A. W. Elliott*. “Cryopreservation of Endothelial Monolayers”.

Reid Bokenfohr*, Kelly Anderson, Leah Marquez-Curtis, Locksley McGann, Janet A. W. Elliott. “Cryopreservation of Human Cerebral Micro-vascular Endothelial Cells”.

Leah Marquez-Curtis*, Kelly Anderson, Xiao-Qing Dai, Locksley E. McGann, Janet A. W. El-liott. “Validation Experiments in a Cryobiology Lab”.

Poster presentations 1. Leah A. Marquez-Curtis*, Kelly Anderson, Reid

Bokenfohr, Locksley E. McGann, Janet A. W. Elliott. “Validation Experiments in a Cryobiology Lab”. DRIvE Days, University of Alberta, April 12-13, 2019.

2. Kezhou Wu, Nadia Shardt, Leila Laouar, Janet A. W. Elliott, Nadr M. Jomha*. “Comparison of Three Multi-cryoprotectant Loading Protocols for Vitrification of Articular Cartilage”. Tom Williams Surgical Research Day, Uni-versity of Alberta, May 10, 2019.

Invited talks 1. Janet A. W. Elliott. “Equilibrium and solution thermody-

namics in cryobiology”. 15th International Conference on Properties and Phase Equilibria for Product and Pro-cess Design (PPEPPD2019), Vancouver, BC, Cana-da, May 12-16, 2019.

Presentations (cont’d)

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

Drs. Janet Elliott & Locksley McGann (cont’d): 2. Janet A. W. Elliott. “Thermodynamics, cryobiology, and

cryopreservation”, School of Biomedical Engineering Seminar, The University of British Columbia, May 17, 2019.

Ms. Anne Halpin: American Society of Transplantation Cutting Edge of Re-search (AST CEoT) meeting (Phoenix, AZ) February 22, 2019 “Next Gen’ ABO Antibody Assessment: Development of a Bead-Based ABO Antibody Detection Assay”. **Was awarded the “Young Innovator Abstract Award” for this ab-stract.**

Dr. Nausherwan Mahmood: “Merkel cell carcinoma: Introduction, new advances & current staging criteria.” Mahmood MN. DRIvE conference. Ven-ue: Glacier Room, Lister Centre, University of Alberta, Edmonton, AB, Canada. April 13th, 2019.

Dr. Michael Mengel: Invited lectures: 1. The Transplantation Society International consensus

conference (March 06. – 07.) 2019, Los Angeles, USA: Develop Consensus Guidelines for Diagnosis and Treatment of Anti-Body Mediated Rejection – “Update on the Banff Criteria for The Diagnosis of Kidney: unresolved issues and controversies”

2. 33rd Advanced HLA Technical Workshop (March 11.-14.) 2019, Rancho Mirage, USA: “STAR 2019 up-date – Antibody Attributes”.

Dr. Josh Raizman: Steven V Dang, Albert Tsui, and Joshua E Raizman. “Wine coloured samples? Development of laboratory reporting guidelines for hydroxycobalamin interference in patients pulled from House Fires”, DRIVE Days, Edmonton, Alberta, April 19-20, 2019. Dr. Farshid Siadat: “Making Sense of Pathology Report in Prostate Cancer, and how the pathologist can predict the outcome”. Prostate Edmonton Peer Support Society (Prostate Cancer Canada Network), Kaye Edmonton Clinic, 12 Feb 2019. Dr. Iveta Sosova: M Chard, S Jain, A Chan, K Siriwardena, I Sosova, K Sabo, F Sasarmanc, D Sinasac, W Al-Hertani, R Sparkes, A Khan. “Newborn screening for fatty acid oxidation disorders in Alberta: an impact assessment after 9 years.”. Garrod Symposi-um 2019. Toronto, Ontario, May 9-11, 2019

Dr. Artur Szkotak: Karina Black, Shirley Perry, Artur Szkotak, Brian Wong. “Supplanting Cytomorphology with Flow Cytometric Immunophe-notyping for Identifying Leukemia in Cerebrospinal Fluid of Pedi-atric Patients”. University of Alberta Pediatric Research Day, May 15, 2019, Edmonton, AB. Dr. Elona Turley Invited speaker: "Laboratory Investigation of Transfusion Reactions". Canadian Society for Transfusion Medicine 2019 Annual Confer-ence, Calgary Alberta. May 30, 2019. Poster Presentations: 1. International Society for Laboratory Hematology

Annual Symposium, Vancouver British Columbia. May 9-11, 2019.

Turley E, Goudreau B, Nahirniak S, Szkotak A, Bodnar M. “Whole Blood is Not Equivalent to Plasma Using the Triage D-Dimer Assay”.

Wong B, Turley E. “A Web-based Tool for Generat-ing Bone Marrow Synoptic Reports”.

2. Turley E, Noga T, Clarke G, Nahirniak S. “Naturally occurring anti-I with broad thermal amplitude in a neonate.” Canadian Society for Transfusion Medicine Annual Conference, Calgary Alberta. May 30-June 2, 2019.

Dr. Lori West: Presentations: 1. The Rotary Club of Edmonton, Invited Speaker, Ed-

monton, AB, May 27, 2019. “Transplant Canada: Har-nessing research toward finding cures”.

2. GlycoNet Annual General Meeting at the Canadian Glycomics Symposium, Invited Speaker, Banff, AB, May 14, 2019) -Team 2016; Theme - Chronic Diseas-es. “Immune responses to polysaccharides in transplantation (CD-29.”

3. The Inaugural Janet Rossant Lectureship, 2019 Mas-sey Grand Rounds (MGR) Symposium on “Healthy Ageing”, Invited Keynote Speaker, University of To-ronto, Toronto, Ontario, March 20, 2019. “Heart transplantation through the ages: A success story.”

4. British Transplantation Society and NHS Blood and Transplant Annual Joint Congress 2019, Invited Speaker, Harrogate, England, March 6-8, 2019.

British Transplantation Society organized ses-sion “Let’s talk about sex!”. “Fifty shades of cell therapy: the impact of sex on cells and cell therapy”.

NSBT organized session “A vision for UK transplantation and donation research”. “Communication for research”.

Presentations (cont’d)

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

Dr. Jason Acker: Publications 1. Rutt, T., Eskandari, N., Zhurova, M., Elliott, J.A.W.,

McGann, L.E., Acker, J.P. and Nychka, J.A. “Thermal expansion of substrate may affect adhesion of Chi-nese hamster fibroblast cells to the surface during freezing”. Cryobiology 86: 134-139 (2019).

2. Heddle, N.M., Cook, R.J., Liu, Y., Zeller, M., Barty, R., Acker, J.P., Eikelboom, J. and Arnold, D.M. “The association between donor sex and age and transfusion recipi-ent mortality: An exploratory analysis”. Transfusion 59 (2): 482-491 (2019).

3. Alshalani, A., Li, W., Juffermans, N., Seghatchian, J. and Acker, J.P. “Biological mechanisms implicated in ad-verse outcomes of sex mismatched transfusions. Transfusion and Apheresis Science” (2019). doi://10.1016/j.transci.2019.04.023

Dr. Ben Adam: Dromparis P, Aboelnazar NS, Wagner S, Himmat S, White CW, Hatami S, Luc JGY, Rotich S, Freed DH, Nagendran J, Mengel M, Adam BA. “Ex vivo perfusion induces a time and perfusate dependent molecular repair response in explanted porcine lungs”. Am J Transplant. 2019 Apr;19(4):1024-1036. PMID: 30230229. Dr. Linda Chui: 1. Gill A, Carrillo C, Hadley M, Kenwell R, Chui L.

“Bacteriological analysis of wheat flour associated with an outbreak of Shiga toxin-producing Escherichia coli O121”. Food Microbiol. 2019 Sep;82:474-481. doi: 10.1016/j.fm.2019.03.023. Epub 2019 Mar 22. PMID:31027808

2. Kellner T, Parsons B, Chui L, Berenger BM, Xie J, Burnham CA, Tarr PI, Lee BE, Nettel-Aguirre A, Szelewicki J, Vanderkooi OG, Pang XL, Zelyas N, Freedman SB; Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE). “Comparative Evalua-tion of Enteric Bacterial Culture and a Molecular Multiplex Syndromic Panel in Children with Acute Gastroenteritis”. J Clin Microbiol. 2019 Apr 10. pii: JCM.00205-19. doi: 10.1128/JCM.00205-19. [Epub ahead of print] PMID:30971465.

3. Xie J, Tarr GAM, Ali S, Chui L, Pang XL, Lee BE, Vanderkooi OG, Tarr PI, Zhuo R, Parsons B, Ber-enger B, Kim K, Freedman SB; Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE) and Pediatric Emergency Research Canada (PERC).

Recent Publications

“Pigment Visibility on Rectal Swabs Used to Detect Entero-pathogens: A Prospective Cohort Study”. J Clin Microbiol. 2019 Apr 3. pii: JCM.00213-19. doi: 10.1128/JCM.00213-19. [Epub ahead of print] PMID:30944189

4. Tarr GAM, Lin CY, Lorenzetti D, Chui L, Tarr PI, Hartling L, Vandermeer B, Freedman SB. “Performance of commercial tests for molecular detection of Shiga toxin-producing Escherichia coli (STEC): a systematic review and meta-analysis protocol”. BMJ Open. 2019 Mar 7;9(3):e025950. doi: 10.1136/bmjopen-2018-025950.PMID:30850413

5. Labbé G, Rankin MA, Robertson J, Moffat J, Giang E, Lee LK, Ziebell K, MacKinnon J, Laing CR, Parmley EJ, Agunos A, Daignault D, Bekal S, Chui L, MacDon-ald KA, Hoang L, Slavic D, Ramsay D, Pollari F, Nash JHE, Johnson RP. “Targeting discriminatory SNPs in Sal-monella enterica serovar Heidelberg genomes using RNase H2-dependent PCR.J Microbiol Methods”. 2019 Feb;157:81-87. doi: 10.1016/j.mimet.2018.12.021. Epub 2018 Dec 25.PMID:30592979

Dr. Matthew Croxen: 1. Skowronski DM, Leir S, Sabaiduc S, Murti M, Dickin-

son JA, Olsha R, Gubbay JB, Croxen MA, Charest H, Chan T, Bastien N, Li Y, Krajden M, De Serres G. “Interim estimates of 2018/19 vaccine effectiveness against in-fluenza A(H1N1)”. pdm09, Canada, January 2019. Euro Surveill. 2019 Jan;24(4).

2. Sander MA, Sander MS, Isaac-Renton JL, Croxen MA. “The Cutaneous Microbiome: Implications for Dermatology Practice”. J Cutan Med Surg. 2019 Apr 2:1203475419839939. doi: 10.1177 / 1203475419839939.

3. Skowronski DM, Leir S, De Serres G, Murti M, Dick-inson JA, Winter AL, Olsha R, Croxen MA, Drews SJ, Charest H, Martineau C, Sabaiduc S, Bastien N, Li Y, Petric M, Jassem A, Krajden M, Gubbay JB. “Children under 10 years of age were more affected by the 2018/19 influ-enza A(H1N1)pdm09 epidemic in Canada: possible cohort effect following the 2009 influenza pandemic”. Euro Surveill. 2019 Apr;24(15).

Dr. Tanis Dingle: Boyd, D.A., Lisboa, L.F., Rennie, R., Zhanel, G.G., Dingle, T.C., Mulvey, M.R. 2019. “Identification of a novel metallo-B-lactamase, CAM-1, in clinical Pseudomonas aeruginosa isolates from Canada”. Journal of Antimicrobial Chemotherapy, doi:10.1093/jac/dkz066.

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

Dr. Andrei Drabovich: Peer-reviewed publications Schiza, C.; Korbakis, D.; Jarvi, K.; Diamandis, E.P.; Drabovich, A.P.* “Identification of TEX101-associated pro-teins through proteomic measurement of human spermatozoa homo-zygous for the missense variant rs35033974”. Molecular & Cellular Proteomics, 2019, 18, 338-351. Published on February 1, 2019. *Corresponding author. Book Chapter Drabovich, A.P.*; Martínez-Morillo, E.; Diamandis, E.P. “Chapter 3 - Protein Biomarker Discovery: An Integrated Con-cept” in Proteomics for Biological Discovery, 2nd Edi-tion, edited by T.D. Veenstra and J.R. Yates, Wiley, 2019, 63-88. Published on May 11, 2019. *Corresponding author. Dr. Steven Drews: Peer reviewed 1. Skowronski, D.M., Leir, S., De Serres, G., Murti, M.,

Dickinson, J.A., Winter A.-L., Olsha, R., Croxen, M.A., Drews, SJ., Charest, H., Martineau, C., Sa-baiduc, S., Bastien, N., Li, Y., Petric, M., Jassem, A., Krajden, M., Gubbay, J.B. “Children under 10 years of age were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic in Canada: possible cohort effect following the 2009 influenza pandemic”. Eurosurveillance. 2019; 24 (15).

2. Crowcroft, N.S, Schwartz, K.L., Chen, C., Johnson, C., Li, Y., Marchand-Austin, A., Bolotin, S., Ja-mieson, F.B., Drews, S.J., Russell, M.L., Svenson, L.W., Simmonds, K., Mahmud, S.M., Kwong, J.C. “Pertussis vaccine effectiveness in a frequency matched popula-tion-based case-control Canadian Immunization Research Network study in Ontario, Canada 2009-2015”. Vaccine. 2019 Apr 6. pii: S0264-410X(19)30254-3. doi: 10.1016/j.vaccine.2019.02.047. [Epub ahead of print].

Drs. Janet Elliott & Locksley McGann: Taylor Rutt, Nasim Eskandari, Maria Zhurova, Janet A.W. Elliott, Locksley E. McGann, Jason P. Acker, John A. Nychka. “Thermal expansion of substrate may affect adhe-sion of Chinese hamster fibroblasts to surfaces during freezing”. Cryobiology (2019) 86: 134-139.

Dr. Michael Mengel: Peer-reviewed publications 1. Aubert O, Higgins S, Bouatou Y, Yoo D, Raynaud M,

Viglietti D, Rabant M, Hidalgo L, Glotz D, Legendre C, Delahousse M, Shah N, Sis B, Campbell P, Mengel M, Jouven X, Duong Van Huyen JP, Lefaucheur C, Loupy A. “Archetype Analysis Identifies Distinct Profiles in Renal Transplant Recipients with Transplant Glomerulopathy Associated with Allograft Survival”. J Am Soc Nephrol. 2019 Apr;30(4):625-639.

2. Groenendyk J, Robinson A, Wang Q, Hu M, Tang J, Chen XZ, Mengel M, Alexander RT, Agellon LB, Michalak M. “Tauroursodeoxycholic acid attenuates cyclospor-ine-induced renal fibrogenesis in the mouse model”. Biochim Biophys Acta Gen Subj. 2019, in press..

Book Chapter: Mengel M. “Transcript Analysis of Renal Transplant Biopsies”. Diagnostic Pathology: Kidney Diseases, 3rd Edition, 2019. Authors: Robert Colvin and Anthony Chang, Hardcover ISBN: 9780323661089, Imprint: Elsevier, Published Date 1st edition: 4th November 2015. Dr. Laura Schmitt: Chan ES, Lauzon J, Resch L, Argiropoulos B, Schmitt L, Chadha R. “Atypical Prenatal Ultrasound Presentation and Neuropathological Findings in a Neonate With Alpha Thalassemia Major: A Case Report.”. Pediatric and Developmental Pa-thology, 2019, Mar-Apr;22(2):166-170. Dr. Consolato Sergi: 1. Sergi C. “EPAS 1, Congenital Heart Disease, and High

Altitude: Disclosures by Genetics, Bioinformatics, and Experi-mental Embryology”. Biosci Rep. 2019 Apr 23. pii: BSR20182197. doi: 10.1042/BSR20182197. [Epub ahead of print] PubMed PMID:31015364.

2. Leung AKC, Lam JM, Leong KF, Sergi CM. “Melanonychia striata: clarifying behind the Black Curtain. A review on clinical evaluation and management of the 21st centu-ry”. Int J Dermatol. 2019 Apr 21. doi: 10.1111/ijd.14464. [Epub ahead ofprint] Review. PubMed PMID: 31006857.

3. Isaac DM, Alzaben AS, Mazurak VC, Yap J, Wizzard PR, Nation PN, Zhao YY,Curtis JM, Sergi C, Wales PW, Mager DR, Turner JM. “Mixed lipid, fish oil andsoy-bean oil parenteral lipids impact cholestasis, hepatic phytosterol and lipidcomposition”. J Pediatr Gastroenterol Nutr. 2019 Mar 5. doi: 10.1097 MPG. 0000000000002313. [Epub ahead of print] PubMed PMID: 30889135.

Recent Publications Cont’d ...

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

Dr. Consolato Sergi (cont’d): 4. Sergi C, Shen F, Liu SM. “Insulin/IGF-1R, SIRT1,

and FOXOs Pathways-An Intriguing Interaction Platform for Bone and Osteosarcoma”. Front Endocrinol(Lausanne). 2019 Mar 1;10:93. doi: 10.3389/fendo.2019.00093. eCollection 2019. PubMed PMID: 30881341; PubMed Central PMCID: PMC6405434.

5. Mojiri A, Alavi P, Lorenzana Carrillo MA, Nakhaei-Nejad M, Sergi CM, Thebaud B, Aird WC, Jahroudi N. “Endothelial cells of different organs exhibit heterogeneity in von Willebrand factor expression in response to hypoxia”. Atherosclerosis. 2019 Mar;282:1-10. doi: 10.1016/j.atherosclerosis.2019.01.002. Epub 2019 Jan 12. PubMed PMID: 30665023.

6. Sergi C, Serra N, Colomba C, Ayanlade A, Di Carlo P. “Tuberculosis evolution and climate change: How much work is ahead?” Acta Trop. 2019 Feb;190:157-158. doi: 10.1016/j.actatropica.2018.11.016. Epub 2018 Nov 16. PubMed PMID: 30452890.

7. Yang Y, Shen F, Huang W, Qin S, Huang JT, Sergi C, Yuan BF, Liu SM. “Glucose Is Involved in the Dy-namic Regulation of m6A in Patients With Type 2 Diabe-tes”. J Clin Endocrinol Metab. 2019 Mar 1;104(3):665-673. doi: 10.1210/jc.2018-00619. PubMed PMID: 30137347.

Dr. Iveta Sosova: Peer-reviewed papers Christpher Newell, Aneal Khan, David Sinasac, John Shoffner, Marisa W. Friederich, Johan L.K. Van Hove, Stacey Hume, JaneShearer, Iveta Sosova “Hybrid gel electrophoresis using skin fibroblasts to aid in diag-nosing mitochondrial disease”. Neurol Genet June 2019, 5 (3) e336; DOI: 10.1212/NXG. 0000000000000336 Dr. Albert Tsui: Tsui AK, Lyon ME, van Diepen S, Goudrea BL, Thomas D, Higgins T, Raizman JE, Fuezery AK, Rodriguez-Capote K, EStey M, Cembrowski G. “Analytical Concord-ance of Diverse Point-of-Care and Central Laboratory Troponin I Assays”. Journal of Applied Laboratory Medicine. 2019. Vol 3 (5) 764-774

Dr. Harry Vinters: 1. T. Bilousova, M. Melnik, E. Miyoshi, B.L. Gonzalez,

W.W. Poon, H.V. Vinters, C.A. Miller, M.M. Cor-rada, C. Kawas, A. Hatami, R. Albay 3d, C. Glabe, K.H. Gylys. “Apolipoprotein E/ABeta complex accumu-lates in AD cortical synapses via ApoE receptors and is en-hanced by APOE4”. American J. Pathology 2019 [Epub ahead of print] PMID: 31108099

2. S. Magaki, R. Parks, H.V. Vinters, N. Khanlou. “A 44-year-old female with familial Mediterranean fever, cardio-myopathy and end stage renal disease”. Brain Pathology 2019; 29(2): 312. PMID: 30821026

3. B.W. Kunkle, B. Grenier-Boley, R. Sims, H.V. Vinters, P. Amouyel, G.D. Schellenberg, J.C. Lam-bert, M.A. Pericak-Vance [dozens of authors; GWAS study]. “Genetic meta-analysis of diagnosed Alzheimer’s dis-ease identifies new risk loci and implicates ABeta, tau, im-munity and lipid processing”. Nature Genetics 2019; 51(3): 414-430. PMID: 30820047

4. R.S. Tashjian, H.V. Vinters, W.H. Yong. “Biobanking of cerebrospinal fluid”. Methods Mol. Biol-ogy 2019; 1897: 107-114. PMID: 30539439

5. R.S. Tashjian, R.R. Williams, H.V. Vinters, W.H. Yong. “Autopsy biobanking: Biospecimen procurement, integrity, storage, and utilization”. Methods Mol. Biology 2019; 1897: 77-87. PMID: 30539436

Dr. Lori West: Abstracts 1. Fersovich J, Motyka B, Adam I, Pearcey J, Tao K,

Cairo CW, Cowan J, West LJ: “ABO tolerance following treatment of infant mice with A-expressing MHC-identical erythrocytes”. 39th Annual Meeting and Scientific Ses-sions of the International Society of Heart and Lung Transplantation (ISHLT), April 3-6, 2019, Orlando, FL. Journal of Heart and Lung Transplantation, 2019: 38(4 Suppl. S): S254 (Abst. 622). SRI

2. Bascom RA, Tao K, West LJ: “Compartiive behavior of allogeneic spleen versus bone marrow cells in non-conditioned neonatal mice: Insights into robust heart transplant tolerance”. 39th Annual Meeting and Scientific Sessions of the International Society of Heart and Lung Transplanta-tion (ISHLT), April 3-6, 2019, Orlando, FL. Journal of Heart and Lung Transplantation, 2019: 38(4 Suppl. S): S74 (Abst. 158). SRI.

Recent Publications Cont’d ...

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

Dr. Lori West (cont’d) Peer-reviewed publications 1. Lopez-Abente J, Camino M, Gil N, Panadero E,

Clemente M, Martinez-Bonet M, Urschel S, West LJ, Pion M, Correa-Rocha R: “Basiliximab impairs regulatory T cell (Treg) function: A possible concern for long term graft acceptance in pediatric heart transplantation”. In Preparation, May 2019.

2. Daskhan G, Motyka B, Bascom R, West LJ, Cairo, CW: “Extending the in vivo persistence of synthetic glycoconju-gates using serum-protein binder”. Bioconjugate Chemistry, In Preparation, March 2019.

3. Laprise C, Cole K, Sridhar VS, Marenah T, Crimi C, West LJ, Foster B, Pilote L, Sapir-Pichhadze R: “Sex and gender considerations in transplant research: A scoping re-view”. Transplantation, Submitted (In Decision Pro-cess), May 2019.

4. Anthony SJ, Stinson H, Lazor T, Young K, Hundert A, Santana MJ, Stinson J, West LJ: “Patient-reported out-come measures within pediatric solid organ transplantation: A systematic review”. Pediatric Transplantation, Accepted, April 2019.

5. Halpin A, Nahirniak S, Campbell P, Urschel S, Kim D, West LJ, Pidorchynski T, Buchholz H, Conway J: “HLA allo-immunization following ventricular assist device support: impact of blood products and detection methods across the age spectrum”. Transplantation. Accepted, April 2019.

6. Park JA, Jang JY, Yan JJ, Jeon HJ, Ryu JH, Kim D, Kim H, Chung J, West LJ, Ahn C, Lee JG, Yang J: “Induction of accommodation by Anti-compliment 5 antibody-based immunosuppression in ABO-incompatible heart trans-plantation”. Transplantation, In Press, May 2019.

7. Cuveilier GDE, Nemecek ER, WAhlstrom JT, Kitko CL, Lewis VA, Schechter T, Jacobson DA, Harris AC, Pulsipher MA,Bittencourt H, Choi SW, Caywood EH, Kasow KA, Bhatia M,Oshrine BR, Kheradpour A , Flower A, Chaudhury S, Coulter D, Chewning JH, Joyce M, Savasan S, Pawlowska AB, Megason GC, Mitchell D, Cheerva AC, Lawitschka A, West LJ, Pan B, Al Hamarneh YN, Halevy A, Schultz KR: “Benefits and challenges with diagnosing chronic and late acute GvHD in children using the NIH consensus criteria”. Blood, 2019, Published [Epub Ahead of Print]. PMID 31043425.

8. Melk A, Babitsch B, Claas F, Dipchand A, Eifert S,

Eiz-Vesper B, Epping J, Falk C, Foster B, Geyer S, Gjertson D, Greer M, Haubitz M, Lau A, Maecker-Kolhoff B, Memaran N, Messner HA, Ostendorf K, Samuel U, Schmidt BMW, Tullius SG, West LJ, Wong G, Zimmermann T, Berenguer M: “Equally interchangeable?- How sex and gender affect transplantation”. Transplantation, 2019, Published [Epub Ahead of Print]. PMID 30747857.

9. Anthony SJ, Nicholas D, Regehr C, West LJ: “The heart as a transplanted organ: Unspoken struggles of personal identity among pediatric recipients.” Canadian Journal of Cardiology, 2019: 35(1): 96-99.

10. Zavalkoff S, Shemie SD, Grimshaw JM, Chasse M, Squires JE, Linklater S, Appleby A, Hartell D. Lalani J, Lotherington K, Knoll G, West LJ and the Poten-tial Organ Donation Identification and System Ac-countability (PODISA) Conference Participants: “Potential organ donor identification and system accountabil-ity: Expert guidance from a Canadian consensus conference”. Canadian Journal of Anesthesia, 2019: 66(4): 432-447. Special Article

Recent Publications Cont’d ...

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

DRIvE Discovery, Research, InnoVation and Education

Friday, April 12 & Saturday, April 13, 2018

Awards & Highlights

Post Doctoral Fellow - Dr. Hanyong Peng

MLS - Mr. Elijah Chan

PhD - Ms. Ashley Newbigging

MSc - Ms. Janet Zhou

Oral Presentation Awards (presented by Dr. Michael Mengel)

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

MLT - Ms. Linda Galbraith

Grad PhD - Ms. Ruqayyah Almizraq Grad MSc - Mr. Nicholas Wawryk

Poster Presentation Awards (presented by Dr. Michael Mengel)

MLS - Mr. Steven Dang & Ms. Denise Alano

DRIvE Day Judges

Oral Judges: Ms. Lisa Purdy Dr. Michael Mengel Dr. Mireille Kattar Dr. Hongquan Zhang

Poster Judges: Ms. Roberta Martindale Ms. Shelly Stevens Ms. Kristi Lew Dr. Michael Reid Dr. Andrea Macyk-Davey Ms. Xiufen Lu

Dr. Peter Dromparis Dr. Yanming Liu Dr. Nausherwan Mahmood Dr. Susan Nahirniak Dr. Monika Keelan Dr. Andrei Drabovich

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

Staff Recognition Award chosen by LMP Students' Group

Ms. Katerina Carastathis and Dr. Linda Chui (presented by Jagdeesh Uppal)

Bell McLeod Educational Fund Citizenship Award

Ms. Angela Ma & Ms. Ruqayyah Almizraq

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The Department of Laboratory Medicine and Pathology Faculty of Medicine and Dentistry, University of Alberta

June 2019

The Banff Pathology Course is a

collaborative effort of the Canadian

Association of Pathologists (CAP-

ACP), Department of Laboratory

Medicine and Pathology, University

of Alberta and the Department of

Pathology and Laboratory Medi-

cine, University of Calgary to

provide a continuing medical

education activity for practicing

pathologists, residents and

pathologists' assistants.

Next course:

Sept 5-7, 2019 - Breast

Future Courses:

Sept. 3-5, 2020

Sept. 9-11, 2021

Sept. 8-10, 2022

Banff Centre for Arts and Creativity

107 Tunnel Mountain Dr,

Banff, AB T1L 1H5

Banff Centre for Arts and Creativity,

formerly known as The Banff Centre,

located in Banff, Alberta, was estab-

lished in 1933 as the Banff School of

Drama.

Dr. Richard G. Hegele Professor & Vice-Dean, Research & Innovation

Faculty of Medicine University of Toronto

Dr. RE Bell Memorial Lecturer

Dr. Kim McGregor Director of Medical Affairs | Medical Oncologist

Foundation Medicine Inc. Cambridge, Massachusetts

Dr. John W. Macgregor Memorial Lecturer