chapter 15. elimination of waste products nitrogenous wastes toxins drugs

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Chapter 15

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Page 1: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Chapter 15

Page 2: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Elimination of waste productsNitrogenous wastesToxinsDrugs

Page 3: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Regulate aspects of homeostasisWater balanceElectrolytesAcid-base balance in the bloodBlood pressureRed blood cell productionActivation of vitamin D

Page 4: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Kidneys Ureters Urinary bladder Urethra

Figure 15.1a

Page 5: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Against the dorsal body wall At the level of T12 to L3

The right kidney is slightly lower than the left Attached to ureters Atop each kidney is an adrenal gland

Page 6: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Renal capsuleSurrounds each kidney

Adipose capsuleSurrounds the kidney

Provides protection to the kidney

Helps keep the kidney in its correct location

Page 7: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Renal cortex – outer region

Renal medulla – inside the cortex

Renal pelvis – inner collecting tube

Figure 15.2b

Page 8: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Medullary pyramids – triangular regions of tissue in the medulla

Renal columns – extensions of cortex-like material inward

Calyces – cup-shaped structures that funnel urine towards the renal pelvis

Page 9: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

The structural and functional units of the kidneys

Responsible for forming urine

Main structures of the nephronsGlomerulus

Renal tubule

Page 10: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

The peritubular capillaries reabsorb several materialsSome waterGlucoseAmino acidsIons

Some reabsorption is passive, most is active

Most reabsorption occurs in the proximal convoluted tubule

Page 11: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Nitrogenous waste products

Urea

Uric acid

Creatinine

Excess water

Page 12: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Colored somewhat yellow due to the pigment urochrome (from the destruction of hemoglobin) and solutes

Sterile

Slightly aromatic

Normal pH of around 6

Page 13: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Slender tubes attaching the kidney to the bladder

Continuous with the renal pelvis

Enter the posterior aspect of the bladder

Runs behind the peritoneum

Peristalsis aids gravity in urine transport

Page 14: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Smooth, collapsible, muscular sac Temporarily stores urine

Figure 15.6

Page 15: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Trigone – three openingsTwo from the uretersOne to the urethra

Figure 15.6

Page 16: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Thin-walled tube that carries urine from the bladder to the outside of the body by peristalsis

Release of urine is controlled by two sphincters

Internal urethral sphincter (involuntary)

External urethral sphincter (voluntary)

Page 17: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

LengthFemales – 3–4 cm (1 inch)

Males – 20 cm (8 inches) Location

Females – along wall of the vagina

Males – through the prostate and penis

Page 18: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Functional kidneys are developed by the third month

Urinary system of a newborn

Bladder is small

Urine cannot be concentrated

Page 19: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Control of the voluntary urethral sphincter does not start until age 18 months

Urinary infections are the only common problems before old age

Page 20: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

There is a progressive decline in urinary function

The bladder shrinks with aging

Urinary retention is common in males

Page 21: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Bacteria in the urinary tract Due to: - sexual intercourse - bowel movements - multiple partners - waiting to late to urinate Symptoms - urge to urinate frequently, soreness

in back or urethra, lots of pain or burning sensation

Page 22: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

Urine chemicals crystallize

Causes: high calcium diet Hot weather- dehydration making urine

concentrated heredity

Page 23: Chapter 15.  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs