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NONPROFIT ORG. U.S. POSTAGE PAID BELLMAWR, NJ PERMIT NO. 2134 Office of Continuing Medical Education Johns Hopkins School of Medicine Turner 20, 720 Rutland Avenue Baltimore, Maryland 21205-2195 CONTINUING MEDICAL EDUCATION Johns Hopkins Breast Cancer Conference A Multidisciplinary Perspective The 10 th Biennial March 20-21, 2020 The Hotel at Arundel Preserve Hanover, Maryland Presented by Johns Hopkins Breast Cancer Program Johns Hopkins Kimmel Cancer Center This activity has been approved for AMA PRA Category 1 Credits . Check out our mobile app CloudCME. Organization Code: HopkinsCME hopkinscme.cloud-cme.com/aph.aspx?P=5&EID=21062 March 20-21, 2020 The Hotel at Arundel Preserve Hanover, Maryland Johns Hopkins Breast Cancer Conference A Multidisciplinary Perspective The 10 th Biennial

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NONPROFIT ORG.U.S. POSTAGE

PAIDBELLMAWR, NJ

PERMIT NO. 2134

Office of Continuing Medical EducationJohns Hopkins School of MedicineTurner 20, 720 Rutland AvenueBaltimore, Maryland 21205-2195

CONTINUING MEDICAL EDUCATION

Johns HopkinsBreast Cancer ConferenceA Multidisciplinary Perspective

The 10th Biennial

March 20-21, 2020The Hotel at Arundel Preserve Hanover, Maryland

Presented by

Johns Hopkins Breast Cancer ProgramJohns Hopkins Kimmel Cancer Center

This activity has been approved for AMA PRA Category 1 Credits™

.

Check out our mobile app CloudCME.

Organization Code: HopkinsCMEhopkinscme.cloud-cme.com/aph.aspx?P=5&EID=21062

March 20-21, 2020The Hotel at Arundel Preserve Hanover, Maryland

Johns HopkinsBreast Cancer ConferenceA Multidisciplinary Perspective

The 10th Biennial

DescriptionSince our last conference, the diagnosis, treatment and overall care needs of breast cancer patients have become more complex. This is due to innovative improvements in therapies, better screening processes, and multidisciplinary care models developing across the U.S.. The indications for axillary node dissection continue to change. Immununotherapy with immune checkpoint blockade is achieving startling results in some patients. There are more options for molecular profiling of tumors, as well as more choices about systemic therapies and radiation therapy. There are more and more long term survivors who require intelligent management by primary care providers to maintain a high quality of life. Come listen, learn and actively participate in discussions regarding these topics and more.

Who Should AttendThis activity is intended for radiologists, pathologists, surgeons, medical and radiation oncologists, nurses, nurse practitioners, physician assistants and other professionals involved in prevention, screening, diagnosis and management of breast cancer.

ObjectivesAfter attending this activity, the participant will demonstrate the ability to:• Describe new data and discuss ongoing

controversies in the management of breast cancer. • Apply evolving data to individualizing breast cancer

management.• Identify areas of controversy in neoadjuvant

treatment of breast cancer.

ACCREDITATION STATEMENT The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENT The Johns Hopkins University School of Medicine designates this live activity for a maximum of 11.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

OTHER CREDITSAmerican Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credits™ from organizations accredited by the ACCME. American Academy of Nurse Practitioners National Certification Program accepts AMA PRA Category 1 Credits™ from organizations accredited by the ACCME.The Johns Hopkins University has approved this activity for 11.25 contact hours for non-physicians.

National Commission on Certification of Physician Assistants (NCCPA) PAs may claim a maximum of 11.25 Category 1 credits for completing this activity. NCCPA accepts AMA PRA Category 1 Credits™ from organizations accredited by ACCME or a recognized state medical society.POLICY ON PRESENTER AND PROVIDER DISCLOSUREIt is the policy of the Johns Hopkins School of Medicine that the presenter and provider globally disclose conflicts of interest. The Johns Hopkins School of Medicine OCME has established policies that will identify and resolve conflicts of interest prior to this educational activity. Detailed disclosure will be made prior to presentation of the education.

General InformationREGISTRATIONFriday, March 20, 2020 from 7:00 – 8:00 a.m.

FEESRegister Online: hopkinscme.cloud-cme.com/aph.aspx?P=5&EID=21062

Methods of Payment: We require full payment prior to the start of the activity. On-site payments by credit card only. The registration fee includes instructional materials, continental breakfasts, refreshment breaks and lunch.Physicians ......................................................................................$285Residents*/Fellows*/Nurses/NPs/PAs/ Allied Health Professionals ..................................................$160 *with verification of status

You will receive a confirmation by e-mail. If you have not received it by March 14, 2020, call (410) 502-9636 to confirm that you are registered. A transcript of attendance will be available upon attestation of your credit hours and submission of the post activity online evaluation. The Johns Hopkins University reserves the right to cancel or postpone any activity due to unforeseen circumstances. In this event, the University will refund the registration fee but is not responsible for travel expenses. Additionally, we reserve the right to change the venue to a comparable venue. Under such circumstances registrants will be notified as soon as possible.

LATE FEE AND REFUND POLICYA $50 late fee applies to registrations received after 5:00 p.m. ET on March 14, 2020. A handling fee of $50 will be deducted for cancellation. An additional fee may apply for cancellation of other events, including workshops and social activities. Refund requests must be received by fax or mail by March 14, 2020. No refunds will be made thereafter. Transfer of registration to another Johns Hopkins activity in lieu of cancellation is not possible.

SYLLABUSThe syllabus will be accessible online and via your mobile device in the CloudCME App prior to the activity.

LOCATION AND TRAVEL INFORMATION The Hotel at Arundel Preserve (410) 796-98307795 Arundel Mills Boulevard Hanover, Maryland 21076

HOTEL RESERVATION CUT-OFF DATE: FEBRUARY 18, 2020A limited block of sleeping rooms has been reserved for your convenience and will be available on a first come, first served basis.

The Hotel at Arundel Preserve is an independently owned, boutique hotel with luxury, eco-friendly, accommodations perfectly situated between Baltimore, Washington and Annapolis. The hotel is adjacent to the Arundel Mills Mall and MarylandLive! Casino. Please call the reservations line at (888) 624-4011 and ask to book under the Johns Hopkins Breast Cancer Conference room block, or mention the group code, 200319JHBC. You can also book online at www.hotelarundel.com by clicking the “Make Reservations” tab and entering the group code listed above. The special group rate is $159, single or double, plus tax. Complimentary parking is available onsite. Check-in time is 3:00 p.m. Check-out time is 11:00 a.m.

HOW TO OBTAIN CREDITPost activity, an online evaluation will be available to attendees to evaluate the activity and individual presentations and to identify future educational needs. Upon completion of the evaluation, the learner must attest to the number of hours in attendance. Credits earned will be added to the learner’s transcript and immediately available for print. The last day to access the evaluation and attest to your credits is May 5, 2020.

An outcome survey will be sent to all physician attendees within two months post activity to assist us in determining what impact this activity had on the learner’s practice.

AMERICANS WITH DISABILITIES ACTThe Johns Hopkins School of Medicine fully complies with the legal requirements of the ADA and the rules and regulations thereof. Please notify us if you have any special needs.

To Register or For Further Information

Register Online: hopkinscme.cloud-cme.com/aph.aspx?P=5&EID=21062 Register by Phone .......................................................................................................................................................................(410) 502-9636Register by Fax ..............................................................................................................................................................................(866) 510-7088Confirmation/Certificates/Transcripts ...........................................................................................................................(410) 502-9636General Information ..................................................................................................................................................................(410) 955-2959E-mail the Office of CME ............................................................................................................................................cmenet@jhmi.eduFollow us on Twitter: http://twitter.com/HopkinsCMEFacebook: http://www.facebook.com/HopkinsCMECheck out our mobile app CloudCME Organization Code: HopkinsCME Sponsoring Division Website: www.hopkins-gi.org

For general information, the direct link for this CME activity web page is: hopkinscme.cloud-cme.com/aph.aspx?P=5&EID=21062

ProgramFRIDAY, MARCH 20, 2020

7:00 – 8:00 Registration and Breakfast 8:00 – 8:10 Welcome and Conference Goals

Vered Stearns, MD and Karen Smith, MD, MPH

Session 1: Updates in Management of Metastatic Breast Cancer 8:10 – 8:30 Evolving Strategies for Triple Negative Metastatic

Breast Cancer Mary Wilkinson, MD

8:30 – 8:50 New Developments in Treatment of Metastatic HER2-Positive Breast Cancer Christie Hilton, DO, MS

8:50 – 9:10 Advances in Treatment for Hormone Receptor-Positive Metastatic Breast Cancer Raquel Nunes, MD

9:10 – 9:30 Precision Medicine: Incorporating Tumor Genomic Assays into Decision-Making for Patients with Metastatic Breast Cancer Jessica Tao, MD

9:30 – 10:10 Case Panel: Challenging Metastatic Breast Cancer Cases Panel Leader: Mary Wilkinson, MD Other Panelists: Fariba Asrari, MD; John Fetting, MD; Christie Hilton, DO, MS; Lisa Jacobs, MD; Raquel Nunes, MD; Jessica Tao, MD

10:10 – 10:25 Refreshment Break

Session 2: New Developments in Genetic Testing and Treatment of Hereditary Breast Cancer 10:25 – 10:45 Should Every Patient with Breast Cancer Undergo

Genetic Testing? David Euhus, MD

10:45 – 11:05 Choosing the “Right” Genetic Test and Integrating Results into Clinical Decision-Making Kala Visvanathan, MD, MHS

11:05 – 11:25 PARP Inhibitors and Beyond: Treatment of BRCA-Mutation-Associated Breast Cancer Deborah Armstrong, MD

11:25 – 12:00 Case Panel: Challenging Genetic Cases Panel Leader: David Euhus, MD Other Panelists: Deborah Armstrong, MD; Lisa Mullen, MD; Maureen O’Donnell Debritz, MD; Dana Petry ScM, CGC; Susan Stinson, MD; Jessica Tao, MD; Kala Visvanathan, MD, MHS

12:00 – 12:45 Lunch

Session 3: Managing Breast Cancer Risk 12:45 – 1:00 Changes in Guidelines for Lobular Neoplasia

Melissa Camp, MD, MPH 1:00 – 1:20 Ordering Wisely: Selecting an Imaging Approach According

to Age, Density, Risk Level and Symptom Kelly Myers, MD

Session 4: Challenging Issues in the Neoadjuvant Setting 1:20 – 1:40 Patient Selection: Indications for Neoadjuvant Therapy

Rima Couzi, MBBCh, MHS 1:40 – 2:00 Imaging Evaluation Before and After Neoadjuvant Therapy

Eniola Oluyemi, MD 2:00 – 2:20 Managing the Axilla After Neoadjuvant Therapy

Julie Lange, MD 2:20 – 2:35 Prognostic Impact of Residual Disease

Andrea Richardson, MD, PhD 2:35 – 2:55 Radiation Decisions After Neoadjuvant Therapy

Amanda Walker, MD 2:55 – 3:10 Refreshment Break

Session 5: Keynote Speaker and Neoadjuvant Case Panel 3:10 – 3:55 Tailoring Post-Neoadjuvant Therapy Based on Response to

Neoadjuvant Therapy Angela DeMichele, MD, MSCE

3:55 – 4:30 Neoadjuvant Case Panel With the Experts Panel Leader: Antonio Wolff, MD Other Panelists: Rima Couzi MBBCh, MHS; Angela DeMichele, MD, MSCE; Thomas Julian MD, FACS; Julie Lange, MD; Eniola Oluyemi, MD; Tatiana Prowell, MD; Andrea Richardson, MD, PhD; Amanda Walker, MD

4:30 – 4:40 Closing Remarks Vered Stearns, MD

SATURDAY, MARCH 21, 2020

7:00 – 8:00 Registration and Breakfast 8:00 – 8:05 Welcome and Conference Goals

Vered Stearns, MD and Karen Smith, MD, MPH

Session 6: Updates in Adjuvant Systemic Therapy 8:05 – 8:25 Use of Genomic Assays to Guide Adjuvant

Systemic Therapy Karen Smith, MD, MPH

8:25 – 8:45 Adjuvant Endocrine Therapy: Selecting Regimen and Duration Vered Stearns, MD

8:45 – 9:15 Case Panel: Challenging Adjuvant Therapy Cases Panel leader: Karen Smith, MD, MPH Other Panelists: Sara Dudley, MD; Cesar Santa-Maria, MD; Jenni Sheng, MD; Vered Stearns, MD

Session 7: Transitioning to a Healthy Survivorship 9:15 – 9:35 Lifestyle Modification

Jenni Sheng, MD 9:35 – 9:55 Imaging of the Post-Op and Reconstructed Breast

Emily Ambinder, MD, MS 9:55 – 10:15 Lymphedema: Facts on Management, Risk Reduction

and Lifestyle Jessica Engle, DO; Laurie Fitz, PT

10:15 – 10:30 Refreshment Break

Session 8: Innovations 10:30 – 10:45 New Imaging Innovations

Lisa Mullen, MD 10:45 – 11:00 Protons: State of the Data

Christina Tsien, MD 11:00 – 11:15 Emerging Biomarkers

Marissa White, MD 11:15 – 11:30 What’s New in Breast Reconstruction?

Michele Manahan, MD 11:30 – 11:45 Evolving Role of Checkpoint Inhibitors in Breast Cancer

Cesar Santa-Maria, MD 11:45 – 12:00 Closing Discussion 12:00 AdjournYou will receive an email notification to complete the evaluation form and to attest to the number of hours in attendance. The registration desk will remain open during conference hours.

ACKNOWLEDGEMENTApplications for commercial support from health care related industries are pending. A complete list of contributors will be provided in the syllabus. Please note that commercial support received is solely for the educational component of the activity and will not be used to provide food and beverage.Please note: The Physician Payments Sunshine Act was enacted by Congress to increase public awareness of financial relationships between drug and medical device manufacturers and physicians. In compliance with the requirements of this Act, the commercial supporter/s of this activity may require the Johns Hopkins School of Medicine to report certain professional information (such as name, address, National Provider Identifier (NPI), and State License number) of physician attendees who receive complimentary food and beverage in conjunction with a CME activity. The commercial supporter is required to submit the collected data to the Centers for Medicare and Medicaid Services which will then publish the data on its website.

The Johns Hopkins School of Medicine takes responsibility for the content, quality and scientific integrity of this CME activity. This schedule is subject to change.

SpeakersACTIVITY DIRECTORSVered Stearns, MDProfessor of OncologyDirector, Women’s Malignancies Disease GroupBreast Cancer Research in OncologyKaren Lisa Smith, MD, MPHAssistant Professor of Oncology

PLANNING COMMITTEESara Alcorn, MD, MPHAssistant Professor of Radiation Oncology and Radiation Molecular ScienceLisa Mullen, MDAssistant Professor of Radiology and Radiological Science Breast Imaging DivisionLisa Jacobs, MDChief of Breast SurgeryAssociate Professor of Surgery

JOHNS HOPKINS SPEAKERSEmily Ambinder, MD, MSInstructor of Radiology and Radiological ScienceDeborah Armstrong, MDDirector, Breast and Ovarian Surveillance ServiceProfessor of OncologyFariba Asrari, MDDirector, Johns Hopkins Breast CenterGreen Spring StationMelissa Camp, MD, MPHAssistant Professor of SurgeryAssociate Program Director, Halsted General Surgery Residency ProgramRima Couzi, MBBCh, MHSAssistant Professor of OncologySara Dudley, MDInstructor of Radiation Oncology and Molecular Radiation ScienceJessica Engle, DOAssistant Professor of Physical Medicine and Rehabilitation

David Euhus, MDProfessor of SurgeryJohn Fetting, MD Associate Professor of OncologyLaurie Fitz, PT Physical Therapist Physical Medicine and RehabilitationJulie Lange, MDAssociate Professor of SurgeryMichele Manahan, MDDepartment Director of Patient Safety Plastic and Reconstructive SurgeryAssociate Professor of Plastic and Reconstructive SurgeryKelly Myers, MDAssistant Professor of Radiology and Radiological ScienceRaquel Nunes, MDAssistant Professor of OncologyEniola Oluyemi, MD Assistant Professor of Radiology and Radiological ScienceMaureen O’Donnell Debritz, MDClinical Associate Department of Surgery, Breast DivisionDana Petry, ScM, CGCGenetic CounselorDepartment of OncologyTatiana Prowell, MDAssociate Professor of Oncology Breast Cancer Scientific Liaison FDA Oncology Center of ExcellenceAndrea Richardson, MD, PhDAssociate Professor of PathologyCesar Santa-Maria, MDAssistant Professor of OncologyJenni Sheng, MDAssistant Professor of OncologySusan Stinson, MD Clinical Associate Medical Director, Suburban Hospital Cancer ProgramJessica Tao, MDAssistant Professor of Oncology

Christina Tsien, MDProfessor of Radiation OncologyMedical Director, Proton Center Department of Radiation Oncology and Molecular Radiation Sciences Kala Visvanathan, MD, MHSProfessor of Epidemiology and Oncology Johns Hopkins Kimmel Cancer Center and Johns Hopkins Bloomberg School of Public HealthDirector, Clinical Cancer Genetics and Prevention ServiceAmanda Walker, MDAssistant Professor of Radiation Oncology and Molecular Radiation SciencesMarissa White, MDAssistant Professor of PathologyMary Wilkinson, MDInstructor of OncologyAntonio Wolff, MDProfessor of Oncology

GUEST SPEAKERSAngela DeMichele, MD, MSCE Professor of Medicine and EpidemiologyJill & Alan Miller Endowed Chair in Breast Cancer ExcellenceCo-Leader, Breast Cancer Research Program Abramson Cancer CenterSenior Scholar, Center for Clinical Epidemiology, Biostatistics and BioinformaticsUniversity of PennsylvaniaChristie Hilton, DO, MSMedical Oncology Lead Allegheny Health Network Breast Cancer ProgramAllegheny Health Network Cancer InstituteThomas Julian MD, FACSAssociate Medical Director Cancer Program Development Allegheny Health Network Cancer Institute Assistant Director Allegheny Health Network Cancer Institute Breast Surgical Fellowship Breast Surgical Oncology Allegheny Health NetworkProfessor of Surgery Drexel University College of Medicine

The 10th Biennial Johns Hopkins Breast Cancer Conference: A Multidisciplinary Perspective

March 20-21, 2020To Register:

Online: hopkinscme.cloud-cme.com/aph.aspx?P=5&EID=21062 Fax: (866) 510-7088 Phone: (410) 502-9636

Or mail this form to the Johns Hopkins University, Office of Continuing Medical Education, 720 Rutland Avenue, Turner Room 20, Baltimore, Maryland 21205-2195. Include e-check or credit card information below.

FULL PAYMENT IS REQUIRED PRIOR TO THE START OF ACTIVITY.

M I am a Johns Hopkins speaker for this activity.

Please type or print clearly:

last name first name m.i.

highest degree primary specialty Hopkins faculty/staff only JHED ID

For Physicians Only:

NPI – 10 digits State License # State of License

mailing address

city state ZIP country

daytime telephone fax number

e-mail

M Check here if you wish to receive e-mail notices about upcoming CME activities.What do you hope to learn by attending this activity?

Please notify us if you have any special needs. ___________________________________________Registration Fees:M Physicians ........................................................................................................................................................$285M Residents*/Fellows*/Nurses/NPs/PAs/

Allied Health Professionals ..................................................................................................................$160* with verification of status

M Patients/Patient Advocates .................................................................................................................$100The registration fee includes instructional materials and food and beverage. For registrations received after 5:00 p.m. ET on March 14, 2020, include a $50 late fee. On-site registrations are payable only by credit card. Total amount $

Payment Type:

M e-Check: Routing Number: Account Number: M Credit Card: M VISA M MASTERCARD M DISCOVER M AMEXCard # - - - _____ Exp. Date

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Name on Card Signature and Date

Registration Form Course Number 80049924/21062

JHU Faculty/Staff Only: If you are using your Tuition Remission Benefit or an ION budget, please upload your fully completed and approved form in the payment section of the online activity link aboveM TR Form: https://hr.jhu.edu/wp-content/uploads/2019/03/trffacandstaff.pdf

M ION Form: http://hopkinscme.edu/migration/IonRequest.pdf