8/23/2019 CHEM 2 Ch 23 Review Questions

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Chem2 Quizbank Ch23 Exam2

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1. T/F 1,25-dihydroxy vitamin D [1,25(OH)2 vitamin D] is the best blood test for determiningadequacy of vitamin D stores in the body

a. False2. Development of ___ ____ is the primary complication of hypercalciuria (increased urinary

excretion of calcium).

a. Kidney Stones3. Skin ____, and kidneys are involved in the production of the active metabolite of Vitamin D.

a. Liver4. ___________ is a type of bone most rapidly lost in response to hypogonadism and

glucocorticoid therapy.

a. Trabecular bone5. T/F Parathyroid hormone (PTH) and 1,25-dihydroxy vitamin D (vitamin D) are the principal

hormones involved in the normal physiologic regulation of calcium homeostasis.

a. True6. T/F 1,25(OH)2 vitamin D, due to i-hydroxylase activity in macrophages, may be produced to

excess in granulomatous diseases and lymphoid disorders, leading to hypercalcemia.

a. True7. T/F hormone Replacement does not inhibit bone resorption in osteoporotic patients

a. False8. _________ ___________ is the most common cause of hypoparathyroidism

a. Neck surgery9. T/F teriparatide is the only drug currently approved by the FDA for treatment of osteoporosis

that directly stimulated bone formation (i.e., it is not an antiresorptive drug).

a. True10.T/F Parathyroid hormone-related protein (PTHrP) is produced by some cancers and often leads

to cancer-associated hypercalcemia

a. True11. In primary hyperparathyroidism, the defect primarily lies in ____________. In secondary

hyperparathyroidism, the defect primarily lies with the threat of ________ to the body.

a. Parathyroids, hypocalcemia12._________ cells in bone are responsible fot bone resorption; and________ cells are responsible

for bone formation,

a. Osteoclasts; osteoblasts13.T/F Cod liver Oil is a source of Vitamin D

a. True14.__________ is the most prevalent metabolic bone disease in the United States

a. Osteoporosis15.The primary organs involved in the maintenance of calcium homeostasis are the intestine, _____

and kidney

a. bone