2001 indole derivatives, isoindole derivatives

indole derivatives, isoindole derivativesR 0140

35 - 1243-(4-Fluoropiperidin-3-yl)-2-phenylindoles as High Affinity, Selective,and Orally Bioavailable h5-HT2A Receptor Antagonists. — Struc-tural optimization among a series of piperidine-substituted indoles leads to (I)as a highly effective component. — (ROWLEY, MICHAEL; ET AL.; J. Med.Chem. 44 (2001) 10, 1603-1614; Merck Sharp Dohme Res. Lab., Neurosci. Res.Cent., Harlow, Essex CM20 2QR, UK; EN)

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