2001 alkaloids

alkaloidsU 0600

16 - 211Chemo-Enzymatic Total Synthesis of 3-Epiaustraline, Australine, and7-Epialexine. — The synthesis of the title compounds (VI), (VIII), and(IX) is achieved via improved epoxidation of the carbinol (I), enzymatic aldolreaction with the phosphate (IV), and bis-reductive amination of the pyranones(V) or (VII). — (ROMERO, ALEX; WONG, CHI-HUEY; J. Org. Chem. 65(2000) 24, 8264-8268; Dep. Chem., Scripps Res. Inst., San Diego, La Jolla, CA92037, USA; EN)

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