Upload File

cheminform abstract: copper-catalyzed tandem process: an efficient approach to...

  • Home
  • Documents
  • ChemInform Abstract: Copper-Catalyzed Tandem Process: An Efficient Approach to 2-Substituted-1,4-benzodioxanes
1
ChemInform 2010, 41, issue 44 © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim www.cheminform.wiley-vch.de Dioxane derivatives R 0470 DOI: 10.1002/chin.201044159 Copper-Catalyzed Tandem Process: An Efficient Approach to 2-Substituted- 1,4-benzodioxanes. — The synthesis of a variety of 2-substituted benzodioxanes (III), (V) is chemoselectively achieved by copper-catalyzed cyclization of iodophenoxy- methyloxiranes in the presence of phenol nucleophiles. In contrast to the previously de- scribed intermolecular reaction of o-iodophenols with oxiranes, tethering of the oxirane to the o-iodophenol allows for selective synthesis of the target benzodioxanes, while the formation of benzodioxepanes as side products is suppressed. — (LIU, Y.; BAO*, W.; Org. Biomol. Chem. 8 (2010) 12, 2700-2703, DOI:10.1039/c003691a ; Dep. Chem., Zhejiang Univ., Hangzhou 310028, Peop. Rep. China; Eng.) — Mischke 44- 159

Upload: yunyun-liu

Post on 11-Jun-2016

215 views

Category:

Documents


2 download

Report

TRANSCRIPT

Page 1: ChemInform Abstract: Copper-Catalyzed Tandem Process: An Efficient Approach to 2-Substituted-1,4-benzodioxanes

www.cheminform.wiley-vch.de

Dioxane derivativesR 0470 DOI: 10.1002/chin.201044159

Copper-Catalyzed Tandem Process: An Efficient Approach to 2-Substituted-1,4-benzodioxanes. — The synthesis of a variety of 2-substituted benzodioxanes (III), (V) is chemoselectively achieved by copper-catalyzed cyclization of iodophenoxy-methyloxiranes in the presence of phenol nucleophiles. In contrast to the previously de-scribed intermolecular reaction of o-iodophenols with oxiranes, tethering of the oxirane to the o-iodophenol allows for selective synthesis of the target benzodioxanes, while the formation of benzodioxepanes as side products is suppressed. — (LIU, Y.; BAO*, W.; Org. Biomol. Chem. 8 (2010) 12, 2700-2703, DOI:10.1039/c003691a ; Dep. Chem., Zhejiang Univ., Hangzhou 310028, Peop. Rep. China; Eng.) — Mischke

44- 159

ChemInform 2010, 41, issue 44 © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

A Protein Complex Network of Drosophila …...A Protein Complex Network of Drosophila melanogaster K.G. Guruharsha,1,4 Jean-Franc¸ois Rual,1,4 Bo Zhai,1,4 Julian Mintseris,1,4 Pujita

Cholesteric Liquid-Crystal Copolyester, Poly[oxycarbonyl- 1,4-phenylene- oxy - 1,4 terephthaloyl- oxy- 1,4-phenylenecarbonyloxy (1,2-dodecane)] [C34H36O8]n, Synthesized from Racemic

Open Access CSgator:kanjintegratedkwebkplatformk forjcompoundksetkanalysis · 2019. 3. 4. · Parkjet al. J Cheminform Pagek6kofk8 currentlackofenoughcompound-targetdataevenafter

Managed to find 2015 installed PostScript fontnames. · /AmericanTypewriter-Light (substituted MM font) /AmericanTypewriter-Medium (substituted MM font) /Amigo (substituted MM font)

Open Access C S :kextractionkandjre-use(ability)k ... · Nguyenjet al. J Cheminform Pagek2kofk9 forthegenerationofcalculatedinformationandidenti-ers.AlthoughtherearesomealternativestoChemDraw,

Review (1,4 MB)

Memory of Chirality in 1,4-Benzodiazepin-2-ones · Significance of 1,4-Benzodiazepin-2-ones……………… ... Biological implications of 1,4-benzodiazepin-2-one ... O-tritylated

Acetylenic Polymers, Substituted

RESEARCHARTICLE Assessingtheinformationcontent ......Rodríguez‑Pérezet al. J Cheminform Page6of14 whichyieldedmedianMCCvaluesof0.67(IFP_85) and0.63(EFCP_folded).us,inhibitorswithbinding

1,* 2,3 4,5 1,4

PSA 1,4 HDI 8V / 1,4 HDI 16V

 · Web view81 1,4-Dioxane 81 81 1,4-Dioxane 1,4-Dioxane 1,4-Dioxane ii i 1,4-Dioxane 1,4-Dioxane ii i ii i 1 0 Priorit y Existin g Chemica l Numbe r 7 1 0 1 0 Priorit y Existin g

NeurobiologyofDisease ... LRRK2InhibitionAttenuatesMicroglialInflammatory Responses MarkS.Moehle,1,4,5*PhilipJ.Webber,1,4,5*ToniaTse,1,4 NourSukar,1,4 DavidG.Standaert,1,4 TaraM.DeSilva

Synthesis of Novel 6-Substituted and 5-Substituted Pyrrolo

Ivan Kisel 1,2,3 , Igor Kulakov 1,4 , Maksym Zyzak 1,4

substituted Alkylthiophenes. A Review Synthesis and ... Gendron and Vamvo… · I. General Preparation of Halo-substituted Alkylthiophenes Halo-substituted alkylthiophenes can be

Interaction of antimutagenic 1,4-dihydropyridine AV-153-Na ... › preprints › 3317.pdfSynthetic derivatives of 1,4-dihydropyridine (1,4-DHPs) possess important biochemical and pharmacological

Latihan Formatif 1,4 Answer

Current Chemistry Letters Solvent-free synthesis and ... · aromatization of 1,4-dihydropyridines (1,4-DHP’s). The 1,4-DHP’s and their oxidized derivatives belong to such immensely

m i s r y: Curr Organic Chemistry El-Azm et al., Organic ... · Synthesis of 4-substituted chlorophthalazines. Scheme 13: Synthesis of 2-ethenyl-3-methyl-2,3-dihydrophthalazine-1,4-diones

ExpressionofPresenilin1and2(PS1andPS2)inHumanand …ExpressionofPresenilin1and2(PS1andPS2)inHumanand MurineTissues MichaelK.Lee,1,4 HildaH.Slunt,1,4 LeeJ.Martin,1,2,4 GopalThinakaran,1,4

NucleophilicT rifluoromethylationof !Substituted ...n Lilja.pdf · NucleophilicT rifluoromethylationof !Substituted Hexasilacyclohexane!andt heSynthesisofa TitanasiloxaneComplex !!!!!

N-327C Improved Coil Coating Performance with EASTMAN 1,4 … · 2013-01-09 · PIA AD 1T 0T 2T 3T 1,4-CHDA PIA AD 1T 3T 2T 4T 1,4-CHDA PIA AD 1H 2H F 1,4-CHDA PIA AD 2T 1T 1,4-CHDA

ChemInform RxnFinder

METHODOLOGY Ecientiterativevirtualscreening with … · 2018. 3. 1. · Ahmed et al. J Cheminform Page4of8 10contain‘high-scoring’ligands.eunassignedbin3is excludedfromtraining.Figure

SYNTHESIS OF HETEROCYCLIC AMINE SUBSTITUTED …etd.lib.metu.edu.tr/upload/12608317/index.pdf · synthesis of heterocyclic amine substituted novel 1,4-aminoalcohols and applications

RESEARCHARTICLE LargescalecomparisonofQSAR … · 2020. 3. 19. · Boscet al. J Cheminform Page3of16 Dta preparation Compoundstructureswereextractedfromthedatabase inSMILESformatandusingRDKit(version2017_09_01)

extent of the difference between the market rates of substituted item and the agreement item (to be substituted). In the case of contract items, substituted items, contract cum substituted

An expedient and facile route for the general synthesis of ......An expedient and facile route for the general synthesis of 3-aryl substituted 1,2,3-triazolo[1,5-a][1,4]benzodiazepin-6-ones

Supporting information 1 · 2013-04-30 · 1 Supporting Information 1 A new MCM-41 supported HPF 6 catalyst for the library synthesis of highly substituted 1,4-dihydropyridines and

1,4 Butanediol (i,4 Bd) - Who | World Health Organization · to make gamma-butyrolactone ... 1,4-Butanediol; ... information relating to the abuse of 1,4-butanediol itself (convertible

Poly(1,4-phenylene vinylene) Derivatives with Ether ...lee.chem.uh.edu/2019/Poly(1,4-phenylene vinylene...Poly(1,4-phenylene vinylene) Derivatives with Ether Substituents to Improve

ASYMMETRIC SYNTHESIS OF N-ARYL SUBSTITUTED ...etd.lib.metu.edu.tr/upload/12608489/index.pdfThe asymmetric synthesis of N-aryl substituted chiral 1,4-aminoalcohols and their applications

1,4-Dioxane Groundwater Contamination

R -I (5 equiv.) · procedures for either the removal or the modification of 1,4-substituted 1,2,3-triazoles. Our ... triazolium iodide is also reported to confirm the regioselectivity