cheminform abstract: facile preparation of cyclopropylamines from carboxamides
TRANSCRIPT
1997 cyclopropane derivatives
cyclopropane derivativesQ 0021
29 - 066Facile Preparation of Cyclopropylamines from Carboxamides. — Anew, general method for the synthesis of cyclopropylamines by Ti(II)- mediatedcoupling of terminal olefins and carboxamides is developed. The diastereoselec-tivity of the aminocyclopropane formation is moderate. This method can beapplied to intramolecular processes providing bicyclic cyclopropylamines. —(LEE, J.; CHA, J. K.; J. Org. Chem. 62 (1997) 6, 1584-1585; Dep. Chem.,Univ. Ala., Tuscaloosa, AL 35487, USA; EN)
1