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Choice Based Credit System (CBCS)

SCHEME OF STUDIES & EXAMINATIONS

M.Sc. in Chemistry (Four-Semester Course)(Effective from Session 2018-2019)

DEPARTMENT OF CHEMISTRY

DEENBANDHU CHHOTU RAM UNIVERSITY OF SCIENCE &TECHNOLOGY

MURTHAL (SONEPAT) HARYANA – 131039

1

Course Structure

S. no.

Course Theory Lab Total CreditNumber Credit Number Credit

1 Core Courses 6+3 6x4+ 3x3

6 6x4 57

2 Elective Coursesa) Open Elective 2 2x3 06b) Discipline Specific

Elective5 5x4 4 4x4 36

3 Ability Enhancement Courses

2 2x2 04

4 Skill Enhancement Course

1 1x3 3

Course Credit 106

Note: Credit requirement for completion of M.Sc. (Chemistry) program: 106 (Grade D or above)

Semester I: 27; Semester II: 27; Semester III: 27; Semester IV: 25

Approved in the 13th meeting of Academic Council held on 18.06.2018

DEENBANDHU CHHOTU RAM UNIVERSITY OF SCIENCE &TECHNOLOGYMURTHAL (SONEPAT) HARYANA – 131039


SCHEME OF STUDIES & EXAMINATIONSM.Sc. in Chemistry (Four-Semester Course)

(Effective from Session 2018-2019)

Semester – ICourse opted

Paper No.

Paper title TeachingScheme

Examination Scheme Duration of Exam(Hours)

Credit

L T P Sessional Marks

ExternalMarks

Total

Core Course CH501C Inorganic Chemistry-I(Essential Inorganic Chemistry-1)

4 0 0 25 75 100 03 4

CH503C Organic Chemistry-I(Structure & Mechanism in Organic Chemistry-1)

4 0 0 25 75 100 03 4

CH505C Physical Chemistry-I(Thermodynamics and Electrochemistry)

4 0 0 25 75 100 03 4

Skill Enhancement

CH507C Computer for Chemists 3 0 0 25 75 100 03 3

Core LabCH509C Inorganic Chemistry Lab-I 0 0 8 25 75 100 08 4CH511C Organic Chemistry Lab-I 0 0 8 25 75 100 08 4CH513C Physical Chemistry Lab-I 0 0 8 25 75 100 08 4

Total 15 0 24 175 525 700 27

Note: 1. Credit requirement for completion of this semester: 27. Credit requirement for completion of programme: 106

(Grade D or above)


DEENBANDHU CHHOTU RAM UNIVERSITY OF SCIENCE &TECHNOLOGYMURTHAL (SONEPAT) HARYANA – 131039


SCHEME OF STUDIES & EXAMINATIONSM.Sc. in Chemistry (Four-Semester Course)

(Effective from Session 2018-2019)

Semester – IICourse Opted

Paper No.

Paper title TeachingScheme

Examination Scheme Duration of Exam

(Hours)

Credit

L T P Sessional Marks

ExternalMarks

Total

Core Course

CH502C Inorganic Chemistry-II( Essential Inorganic Chemistry-2)

4 0 0 25 75 100 03 4

CH504C Organic Chemistry-II(Structure & Mechanism in Organic Chemistry-2)

4 0 0 25 75 100 03 4

CH506C Physical Chemistry-II( Kinetics, Quantum Mechanics and Photochemistry )

4 0 0 25 75 100 03 4

CH508C Spectroscopy- I (Molecular Spectroscopy)

3 0 0 25 75 100 03 3

Core Lab CH510C Inorganic Chemistry Lab-II 0 0 8 25 75 100 08 4

CH512C Organic Chemistry Lab-II 0 0 8 25 75 100 08 4

CH514C Physical Chemistry Lab-II 0 0 8 25 75 100 08 4

Total 15 0 24 175 525 700 27

Note: 1. Credit requirement for completion of this semester: 27. Credit requirement for completion of programme: 106

(Grade D or above)


M.Sc. Chemistry Semester-IInorganic Chemistry - I (Essential Inorganic Chemistry-I)

Paper No. CH501C Credits: 0404 Hrs /week External Marks: 75Duration of Exam: 03 Hrs Internal Marks: 25

Note: The question paper will comprise of eight questions, two from each unit. The candidates will be required to attempt five questions selecting at least one from each unit. All questions will carry equal marks.

UNIT-I

Theories of Bonding in Co-ordination Complexes: Valence bond theory and limitations, Crystal field theory, splitting of d-orbitals in different geometries (octahedral, tetragonal, tetrahedral and square planar), Structural consequences of splitting of d-orbitals, Jahn Teller distortion, trends in ionic radii, lattice energy and heat of ligation, Structure of spinels, Limitation of CF Theory, Molecular Orbital Theory with and bonding (octahedral, tetrahedral and square planar complexes).

UNIT-II

Reaction Mechanism of Transition Metal Complexes - I Energy profile of a reaction, reactivity of metal complexes, inert and labile complexes, kinetic application of valence bond and crystal field theories, kinetics of octahedral substitution, acid hydrolysis, factors affecting acid hydrolysis, base hydrolysis, conjugate base mechanism, direct and indirect evidences in favour of conjugate mechanism, anation reactions.

UNIT-III

Reaction Mechanism of Transition Metal Complexes - II Mechanism of the substitution reactions in square planar complexes, the trans effect, theories of trans-effect, Redox reactions, electron transfer reactions: mechanism of one electron transfer reactions, outer sphere type reactions, inner sphere type reactions, Illustrative examples

UNIT-IV

Metal-Ligand Equilibria in Solution: Stepwise and overall formation constants and their interaction, trends in stepwise constants, factors affecting the stability of metal complexes with reference to the nature of metal ion and ligand. chelate effect and its thermodynamic origin, determination of binary formation constants by pH-metry and spectrophotometry.Stereochemistry and Bonding in Main Group compounds: VSEPR theory, d-p bonds, Bent rule and energetic of hybridization.

Books Suggested:

1. Shriver & Atkins: Inorganic Chemistry, P.W. Atkins, T. Overton, J. Rourke, M. Weller and F. Armstrong, Oxford University Press.


2. Inorganic Chemistry: Principles of Structure and Reactivity, J.E. Huhey, E.A. Keiter and R.L. Keiter, Pearson Education.

3. Modern Aspects of Inorganic Chemistry, H.J. Emeleus and Sharpe.4. Chemical Bonding, O.P. Aggrawal, 5. General and Inorganic Chemistry Part-II, R.P. Sarkar, New Central Book Agency (P) Ltd 6. Advanced Inorganic Chemistry, F.A. Cotton and Wilkinson, John Wiley.7. Inorganic Chemistry, Weller, Overton, Rourke and Armstrong, Oxford, 6th ed.8. Selected Topics in Inorganic Chemistry, Tuli , Malik and Madan, S. Chand & Company.9. Inorganic Chemistry, J.E. Huheey, HarperCollins.10. Chemistry of the Elements, N.N. Greenwood and A. Earnshaw, Pergamon.11. Inorganic chemistry, G. Wulf’sburg.12. Introduction to ligand fields, B.N. Figgis, Wiley Eastern-IIed.13. Mechanism of Inorganic Reactions, F. Basolo and R.G. Pearson, John Wiley and Sons, New

York.14. Inorganic Reaction Mechanism, M.L. Tobe; Nelson, Wlaton and Thames


M. Sc. Chemistry Semester-I Organic Chemistry - I (Structure & Mechanism in Organic Chemistry-I)



UNIT-I

Nature of Bonding in Organic Molecules: Delocalized chemical bonding- conjugation, cross conjugation, resonance, hyperconjugation, bonding in fullerenes, tautomerism, Aromaticity - Benzenoid and non-benzenoid compounds, alternant and non-alternant hydrocarbons, Hückel’s rule, annulenes, anti-aromaticity, homo-aromaticity. Bonds weaker than covalent bond, crown ether complexes, cryptands, inclusion compounds, cyclodextrins, catenanes and rotaxanes.

UNIT-II

Stereochemistry: Nomenclature systems D&L, R&S and E&Z, CIP rules. Conformational analysis of cycloalkanes, decalins, effect of conformation on reactivity, conformation of sugars. Elements of symmetry, chirality, molecules with more than one chiral centre, asymmetric synthesis (basic principle), cram`s rule, Prelog rule. Methods of resolution, optical purity, enantiotopic and diastereotopic atoms, groups and faces, stereospecific and stereoselective synthesis. Optical activity in the absence of chiral carbon (biphenyls, allenes and spiranes); Stereochemistry of the compounds containing nitrogen, sulphur and phosphorus.

UNIT-III

Reaction Mechanism: Structure and Reactivity: Types of reactions, kinetics and thermodynamics of the reaction, kinetic and thermodynamic control, Hammond’s postulate, Curtin-Hammett principle. Potential energy diagrams, transition states and intermediates, methods of determining mechanisms, isotope effects. Generation, structure, stability and reactivity of carbocations, carbanions, free radicals, carbenes and nitrenes,effect of structure on reactivity – resonance and field effects, steric effect. Hammett equation and linear free energy relationship.

UNIT-IV

Chromatographic Techniques: Types of chromatography, Principle, Instrumentation and applications of Thin layer Chromatography, Column Chromatography, High Performance Liquid Chromatography (including concept of theoretical plates & reverse HPLC), Gas Chromatography, GPC(Gel permeation chromatography).

Books Suggested

1. Advanced Organic Chemistry, F.A. Carey and R.J. Sundburg, Springer.2. Organic Chemistry, R.T. Morrison and R.N. Boyd, Pearson.


3. Organic chemistry, J. Clayden , N. Greeves and S. Warren, Oxford University Press.4. Stereochemistry of Organic Compounds, D. Nasipuri, New Age International.5. Stereochemistry of Organic Compounds, P.S. Kalsi, New Age International.6. Structure and Mechanism in Organic Chemistry, C.K. Ingold, CBC Publisher & Distributors,

1995.7. Advanced Organic Chemistry-Reactions, Mechanism and Structure, Jerry March, John Wiley. 8. Stereochemistry of Organic Compounds, E. L. Eliel and S. H. Wilen, Wiley Interscience.9. Reaction Mechanism in Organic Chemistry, S M Mukherji and S P Singh revised by S P Singh and

Om Prakash, Trinity.10. Organic reaction Mechanism, V K Ahluwalia and R K Prasher, Narosa Publishing House.11. Instrumental methods of analysis by B. K. Sharma, Krishna Prakashan Media.12. Instrumental methods of analysis by Willard Merritt, Deen.


M.Sc. Chemistry Semester-I Physical Chemistry-I (Thermodynamics and Electrochemistry)

Paper No. CH505C Credits: 04 04 Hrs/week External Marks: 75Duration of Exam: 03 Hrs Internal Marks: 25


UNIT-I

Thermodynamics: Brief resume of First and Second law of thermodynamics. Classius-Clayperon equation; law of mass action and its thermodynamic derivation. Third law of thermodynamics (Nernest heat theorem, determination of absolute entropy, unattainability of absolute zero) and its limitation. Phase diagram for two completely miscible components systems. Eutectic systems, Calculation of eutectic point, systems forming solid compounds AxBy with congruent and incongruent melting points, phase diagram and thermodynamic treatment of solid solutions.

UNIT-II

Partial molar properties: Recapitulation of thermodynamic laws, Partial molar quantities, chemical potential and Gibbs-Duhem equation, variation of chemical potential with temperature and pressure, chemical potential for an ideal gas, chemical potential of ideal gas mixture (s), determination of partial molar volume, thermodynamic functions of mixing (free energy, entropy, volume and enthalpy), concept of escaping tendency and chemical potential.

UNIT-III

Electrochemistry I: Ion-Ion Interactions -The Debye -Huckel theory of ion-ion interactions: potential and excess charge density as a function of distance from the central ion, Debye Huckel reciprocal length, ionic cloud and its contribution to the total potential, Debye-Huckel limiting law of activity coefficients and its limitations, ion-size effect on potential, ion-size parameter and the theoretical mean - activity coefficient in the case of ionic clouds with finite-sized ions. Debye-Huckel-Onsager treatment for aqueous solutions and its limitations Debye-HuckelOnsager theory for non-aqueous solutions, the solvent effect on the mobality at infinite dilution, equivalent conductivity vs. concentration c1/2 as a function of the solvent, effect of ion association upon conductivity (Qualitative treatment only).

UNIT-IVElectrochemistry II: Ion Transport in solutions – Ionic movement under the influence of an electric field , mobility of ions, ionic drift velocity and its relation with current density, Einstein relation between the absolute mobility and diffusion coefficient, the Stokes- Einstein relation , the Nernst -Einstein equation, Waldens rule, the Rate-Process approach to ionic migration , the Rate process equation for equivalent conductivity, total driving force for ionic transport, Nernst - Planck Flux equation, ionic drift and diffusion potential , the Onsager phenomenological equations. The basic equation for the diffusion, Planck-Henderson equation for the diffusion potential.


Books Suggested

1. Physical Chemistry, P.W. Atkins, Oxford University Press.

2. Physical Chemistry, G.W. Castellan, Narosa. Publishers, New Delhi

3. Thermodynamics for Chemists, S. Glasstone, Affiliated East-West Press.

4. Chemical Thermodynamics, I.M. Klotz and R.M. Rosenberg, Benzamin.

5. An Introduction to Chemical Thermodynamics, R.P. Rastogi and R.R. Misra, Vikas Pub.

6. Electrochemistry, S. Glasstone

7. Modern Electrochemistry vol.1 and vol II J.O.M.Bockris and A.K.N.Reddy, PlenumPress.

8. Principles of Physical Chemistry, Puri, Sharma and Pathania, Vishal Pub.

9. Advanced Physical Chemistry, Gurtu &Gurtu, Pragati Prakashan .


M.Sc. Chemistry Semester-I

Computer for Chemists


Note: The question paper will comprise of nine questions, two from each unit. The candidates will be required to attempt five questions selecting at least one from each unit. All questions will carry equal marks.

UNIT-I

Computer Fundamentals: Functional components of a digital computer, concepts of hardware and software, binary, octal & hexadecimal number systems. Binary arithmetic, input/output and storage devices, overview of functions of operating system, types of operating systems, features of windows operating system.MS Office: Word, Excel, Power Point, Equation, Math type.Chem Office: Structure of molecules like proteins, DNA, RNA, Sugar, amino acids, heterocyclic compounds, chemical reactions (single step, two step & multistep) using Chem Draw/Chem Office (Free alternatives: Open Office (www.openoffice.org, ISIS Draw (http://www.mdli.com; registration required).Programming Fundamentals: Algorithms, flowcharts, linear and binary search algorithms, bubble sort algorithms. Matrix transpose, matrix addition and matrix multiplication algorithms and their applications.

UNIT-II

Programming in C: Character set, constants and variables, reserved words, data types, expressions, scanf and print statements, operators and their hierarchy, conditional, unconditional and loop control structures. One-dimensional and two-dimensional arrays,Functions.

UNIT-III

Computer Application in Chemistry: Developing programs in C involving simple formulae in chemistry such as van der Waals equation, pH titration, kinetics, radioactive decay, evaluation of lattice energy and ionic radii from experimental data. Linear simultaneous equation to solve secular equations within the Huckel theory, Elementary structural features such as bond lengths, bond angles, dihedral angles etc. of molecules extracted from a database such as Cambridge database.

Books Suggested1. Introduction to Computer Science, P.K. Sinha2. Let Us C, Yashwant Kanetker3. Computational Chemistry, A.C. Norris.


http://www.openoffice.org/

M.Sc. Chemistry Semester-IInorganic Chemistry Lab. - I


1. Inorganic synthesis (any four) (20 Marks)

i. Prussian Blue/Turnbull’s Blueii. VO(acac)2

iii. Mn(acac)3

iv. Hg[Co(NCS)4]v. Na[Cr(NH3)2(SCN)4]

2. Volumetric Analysis (25 Marks)

(a) Potassium iodide titrations Determination of iodide, hydrazine and Antimony (III) (b) Potassium bromate titrations (i) Determination of Antimony (III) ( by Direct Method) (ii) Determination of Aluminium, Magnesium and Zinc (by Oxine method) (c) EDTA titrations (i) Determination of Calcium, Copper, Barium. (ii) Back titration (iii) Titration of mixtures using masking

Distribution of marks for the final practical exam

1. Experimental performance (45 Marks)

2. Viva-Voce (15 Marks)3. Record file (15 Marks)Note: 1. New experiment(s) related to the theory paper syllabus can also be performed in addition to the above list of experiments. 2. Depending on the availability of chemicals/instruments etc., any similar experiment can also be performed as substitute from the above list.

Books Suggested:1. Vogel’s Textbook of Quantitative Analysis, revised, J. Bassett, R. C. Denney, G.H. Jeffery and

J. Mendham, ELBS.2. Vogel’s Textbook of Macro and Semimicro Qualitative Inorganic Analysis, revised, G.

Svehla, Longman.3. Practical Inorganic Chemistry, Marr and Rocket.4.


M.Sc. Chemistry Semester-IOrganic Chemistry Lab. - I


1. Qualitative Analysis (20 marks)

Separation and identification of compounds of binary mixture using water/NaHCO3 and preparation of their suitable derivatives.

2. Organic Synthesis (25 marks)

Two step preparations1. p-Nitroacetanilide from aniline

2. p-Bromo acetanilide from aniline

3. Anthranilic acid from phthalic anhydride

4. Eosin from phthalic anhydride

Purification after first step should preferably be done by using recrystallization or column chromatography.

Note- Department can opt any other similar two step preparation depending upon the material

available.

3. Viva-Voce (15 marks)

4. Note book/Practical file (15 marks)

Books Suggested

1. Experiments and Techniques in Organic Chemistry, D. Pasto, C. Johnson and M. Miller, Prentice Hall.

2. Macroscale and Microscale Organic Experiments, K.L. Williamson, D.C. Heath.3. Systematic Qualitative Organic Analysis, H. Middleton, Adward Arnold.4. Handbook of Organic Analysis-Qualitative and Quantitative, H. Clark, Adward Arnold.5. Vogel’s Textbook of Practical Organic Chemistry, A.R. Tatchell, John Wiley.6. Advanced practical chemistry, Jagdamba, Yadav and shrivastava, Pragati Prakasan.7. Advanced organic practical chemistry, J.N.Gurtu and R. Kappor, S. Chand.8. Advanced practical organic chemistry, N.K. Vishnoi, Vikas Publishing House.9. Organic Analytical Chemistry by Jag Mohan, Narosa Publishing House.


M.Sc. Chemistry Semester-IPhysical Lab-I


1. Viscosity MeasurementsStudy the variation of viscosity with concentration for a given solution using Ostwald viscometer and thereafter determine the concentration of unknown solution.

2. ConductometryDetermine the strength of strong acid by conductometric titration with strong base.Determine the strength of weak acid by conductometric titration with strong base.Determine the strength of strong acid and weak acid in a mixture by conductometric titration with strong base.Study precipitation titration between KCl and AgNO3 conductometrically. Determine the strength of given solution of AgNO3.Determine solubility and solubility product of sparingly soluble salts like PbSO4, BaSO4.Determine the relative strength of chloroacetic acid and acetic acid by conductivity measurements.

3.PotentiometryDetermine the standard electrode potential of Cu and Zn.Determine the strength of a given solution of ferrous ammonium sulphate by potentiometric titration with K2Cr2O7 solution.Study the precipitation titration between KCl and AgNO3 potentiometrically.

4.Chemical KineticsStudy the hydrolysis of methyl acetate in presence of hydrochloric acid.Study saponification of ethyl acetate by sodium hydroxide solution using same initial concentration of both the reactants.Study saponification of ethyl acetate by sodium hydroxide solution taking the initial concentration of ester and base to be different.

5.AdsorptionVerify the Freundlich and Langmuir adsorption isotherms for adsorption of acetic acid/oxalic acid on activated charcoal.

Note: Any experiment can be introduced or deleted in the practical class on the basis of availability of instruments/chemicals.

Experiment Marks: 45Lab record and Viva-voce Marks: 15+15

Books Suggested:1. Yadav J.B., Advanced Practical Physical Chemistry, 29th Edition,Krishna Prakashan

Media(P)Ltd. U.P., Noida.2. Khosla, B.D., Garg, V.C., Gulati, A., Senior Practical Physical Chemistry, 11th edition, Pubs:

R.Chand & Co., New Delhi (2002). 3. Practical Physical Chemistry, A.M. James and F.E. Prichard, Longman.4. Findley’s Practical Physical Chemistry, B.P. Lavitt, Longman.


5. Practical Physical Chemistry, S.R. Palit and S.K. De, Science.6. Experimental Physical Chemistry, R.C. Das and B. Behera, Tata McGraw Hill.7. Systematic experimental physical chemistry, S. W. Rajbhoj and T. K. Chondhekar.


M.Sc. Chemistry Semester-IIInorganic Chemistry –II (Essential Inorganic Chemistry-II)



UNIT-I

Electronic Spectra of Transition Metal Complexes Spectroscopic terms and term symbols, calculation of microstates and ground state terms, spin-orbit coupling in free ions for 1st series of transition metals, Orgel and Tanabe-Sugano diagrams for transition metal complexes (d1–d9 states) calculation of Dq, B and β parameters, Naphelauxetic effect and series, spectrochemical series, charge transfer spectra (metal to ligand, ligand to metal and metal to metal), illustrative examples.

UNIT-II

Magnetic Properties of transition metal complexes Elementary theory of magneto - chemistry, Guoy’s method for determination of magnetic susceptibility, calculation of magnetic moments, various types of magnetism, Curie and Curie-Weiss law for the temperature dependence of magnetic susceptibility, orbital contribution, TIP, effect of ligand-field, application of magneto-chemistry in structure determination, spin state cross over.

UNIT-III

Isopoly and Heteropoly Acids and Salts: Isopoly and Heteropoly acids and salts of Mo and W: Structures of isopoly and heteropoly anions. Chemistry of non-transition elements: Synthesis, properties and structure of boranes, carboranes, borazines, silicates, phosphazenes,Interhalogens, pseudohalides and compounds of noble gas.

UNIT-IV

Non-aqueous Solvents: Protic and aprotic solvents, Solvent system definition, Reactions in non-aqueous media with respect to liquid H2SO4, NH3, SO2, BrF3, N2O4, HF, thionyl chloride and phosphoryl chloride. Reaction in molten salts, Mechanism of coordination reactions in non-aqueous media.


Books Suggested:

1. General and Inorganic Chemistry Part-I & II, R.P. Sarkar, New Central Book Agency (P) Ltd 2. Advanced Inorganic Chemistry, F.A. Cotton and Wilkinson, John Wiley.3. Inorganic Chemistry, Weller, Overton, Rourke and Armstrong, Oxford, 6th ed.4. Selected Topics in Inorganic Chemistry, Tuli , Malik and Madan, S. Chand & Company.5. Inorganic Chemistry, J.E. Huheey, HarperCollins.6. Inorganic Chemistry, Miessler & Tarr, Pearson Prentice Hall, 3rd Ed.7. Chemistry of the Elements, N.N. Greenwood and A. Earnshaw, Pergamon.8. Magnetochemistry, R.L. Carlin, Springer Verlog.9. Magnetochemistry, A. Earnshaw.10. Inorganic chemistry, G. Wulf’sburg.11. Introduction to ligand fields, B.N. Figgis, Wiley Eastern-IIed.


M.Sc. Chemistry Semester-II Organic Chemistry–II (Structure & Mechanism in Organic Chemistry-II)



UNIT-I

Aliphatic Electrophilic SubstitutionBimolecular mechanisms – SE

2 and SEi. The SE

1 mechanism, Effect of substrates, leaving group and the solvent polarity on the reactivity.Aromatic Electrophilic Substitution

The Arenium ion mechanism, orientation and reactivity. The ortho/para ratio, ipso attack, orientation in other ring systems. Diazonium coupling, Vilsmeir reaction, Gattermann-Koch reaction.

UNIT-II

Aliphatic Nucleophilic SubstitutionThe SN

2, SN1, SN

i, mixed SN1 and SN

2 and SET Mechanisms; neighbouring group participation by and bonds; Classical and nonclassical carbocations, phenonium ions, norbornyl system, Nucleophilic substitution at an allylic, aliphatic trigonal and a vinylic carbon. Reactivity effects of substrate structure, attacking nucleophile, leaving group and reaction medium, ambient nucleophile, regioselectivity.Aromatic Nucleophilic Substitution

The SNAr, SN

1, benzyne and SRN1 mechanisms. Reactivity – effect of substrate structure, leaving

group and attacking nucleophile. The von Richter, Sommelet-Hauser, and Smiles rearrangements.

UNIT-III

Free Radical ReactionsTypes of free radical reactions, free radical substitution mechanism, mechanism at an aromatic

substrate, Reactivity in the attacking radicals. The effect of solvents on reactivity. Allylic halogenation (NBS), oxidation of aldehydes to carboxylic acids, auto-oxidation, coupling of alkynes and arylation of aromatic compounds by diazonium salts. Sandmeyer reaction. Elimination Reactions: Type of elimination reactions, E1, E2 and Ecb Mechanisms.Hydrolysis Reactions: Mechanism of Hydrolysis of esters and amides under acidic and basic conditions.


UNIT-IV

Addition to Carbon-Carbon Multiple Bonds Mechanistic and stereochemical aspects of addition reactions involving electrophiles, nucleophiles and free radicals. Hydrogenation of double and triple bonds, hydrogenation of aromatic rings. Hydroboration. Michael reaction. Sharpless asymmetric epoxidation.Addition to Carbon-Hetero Multiple Bonds

Mechanism of metal hydride reduction of carbonyl compounds, acids and esters. Addition of Grignard reagents, organozinc and organolithium reagents to carbonyl compounds. Mechanism of condensation reactions involving enolates – Aldol, Knoevenagel, Claisen, Mannich, Benzoin, Perkin, Stobbe and Wittig Reaction.

Books Suggested:1. Advanced Organic Chemistry-Reactions, Mechanism and Structure, Jerry March, John Wiley. 2. Advanced Organic Chemistry, F.A. Carey and R.J. Sundberg, Plenum.3. A Guide Book to Mechanism in Organic Chemistry, Peter Sykes, Longman.4. Advanced Organic Chemistry: Reaction Mechanism, Reinhard Bruckner, Harcourt (India) Pvt.

Ltd.5. Organic Reaction Mechanism, V K Ahluwalia and R K Prasher, Narosa Publishing House.6. Organic reactions and their mechanisms by P S Kalsi New Age International Publishers.7. Strategic Applications of Named Reactions in Organic Synthesis by Laszlo Kurti(Author),

Barbara Czako from Elsevier. 8. Name Reactions: A Collection of Detailed Mechanisms and Synthetic Applications by Jie

JackLi from Springer.9. The Art of Writing Reasonable Organic Reaction Mechanisms by Robert B. Grossman from

Springer.


M.Sc. Chemistry Semester-II Physical Chemistry –II (Kinetics, Quantum Mechanics and Photochemistry)

Paper No. CH506C Credits: 04 04 Hrs/weekDuration of Exam: 03 Hrs

External Marks: 75Internal Marks: 25


UNIT-I

Quantum Mechanics: Postulates of Quantum Mechanics; formulation of Schrodinger wave equation; Max-Born interpretation of Ψ and the Heisenberg’s uncertainty principle; Quantum mechanical operators and their commutation relation, Hermitian operators, (elementary ideas, quantum mechanical operator for linear momentum and angular momentum as Hermitian operator). The average value of the square of Hermitian operators; commuting operators and uncertainty principle(x andp; E &t); Schrodinger wave equation for a particle in one and three dimensional box; evaluation of average position, average momentum and determination of uncertainty in position and momentum and hence Heisenberg’s uncertainty principle, pictorial representation of the wave equation of a particle in one dimensional box and its influence on the kinetic energy of the particle in each successive quantum level, lowest energy of the particle.

UNIT-II

Chemical Dynamics I: Effect of temperature on reaction rates, Rate law for opposing reactions of Ist order and IInd order, Rate law for consecutive Ist order reactions, Collision theory of reaction rates and its limitations, steric factor, Ionic reactions: single and double sphere models, influence of solvent and ionic strength, Chain reactions: hydrogen - bromine reaction, pyrolysis of acetaldehyde, decomposition of ethane. Photochemical reactions (hydrogen-bromine andhydrogen-chlorine reactions

UNIT-III

Chemical Dynamics II:. General treatment of chain reactions (ortho -para hydrogen conversion and hydrogen - bromine reactions), apparent activation energy of chain reactions, chain length, Rice-Herzfeld mechanism of organic molecules, decomposition(acetaldehyde) Branching chain reactions and explosions ( H2 - O2 reaction). Kinetics of (one intermediate) enzymatic reaction : Michaelis - Menton treatment, evaluation of Michaelis's constant for enzyme-substrate binding by Lineweaver - Burk plot, by Dixon and by Eadie-Hofstae methods. Competitive and non-competitive inhibition.

Unit IV

Photochemistry: Molecular photochemistry: An overview: Transitions between states (Chemical, classical and quantum dynamics, vibronic states). Consequences of light absorption: The Jablonski diagram, Potential energy surfaces; transitions between potential energy surfaces, The Franck-Condon Principle and radiative transitions. A classical model of radiative transitions. The absorption and


emission of light - state mixing, spin-orbit coupling and spin forbidden radiative transitions, absorption complexes, delayed fluorescence and phosphorescence.

Books Suggested



3. Principles of Physical Chemistry, Puri, Sharma andPathania, Vishal Pub.

4. Introductory Quantum Chemistry, A.K. Chandra, Tata McGraw Hill.

5. Quantum Chemistry, I.M. Levine, Prentice Hall.

6. Quantum Mechanics, M.L. Strause, Prentice – Hall

7. Quantum Chemistry, J. P. Lowe andK. Peterson, Academic Press (2005).

8. Theoretical Chemistry, Samual Glasstone Affiliated East-West Press.

9. Molecular Quantum Mechanics, P.W. Atkins andR.S. Friedman, 3rd Ed. Oxford University Press

(1997).

10. Chemical Kinetics Methods, C. Kalidas, New Age International

11. Chemical Kinetics, K.J. Laidler, McGraw Hill.

12. Modern Spectroscopy, J.M. Hollas, John Wiley.

13. Chemical Applications of Group Theory, F.A. Cotton.

14. Introduction to Molecular Spectroscopy, G.M. Barrow, McGraw Hill.

15. Basic Principles of Spectroscopy, G.M. Barrow, McGraw Hill.

16. Fundamentals of molecular spectroscopy, C. N. Banwell, Tata Macgraw Hill.

17. Physical Methods in Chemistry, R.S. Drago, Saunders College.


M.Sc. Chemistry Semester-II Spectroscopy-1(Molecular Spectroscopy)

Paper No. CH508C Credits: 03 03 Hrs/weekDuration of Exam: 03 Hrs

External Marks: 75 Internal Marks: 25


Unit I

Basics Introduction. Electromagnetic radiation, interaction of electromagnetic radiation with matter, regions of the Spectrum, the width and intensity of spectral transitions. Resolving power.Microwave Spectroscopy: The rotation of molecules, rotational spectra of rigid diatomic molecules, intensities of rotational spectral lines, isotopic effect, non-rigid rotator, spectra of polyatomic linear molecules and symmetric top molecules.

Unit II

Infrared Spectroscopy: The vibrating diatomic molecule, force constant, zero point energy, simple harmonic vibrator, anharmonicity, Morse potential, overtones, hot bands, diatomic vibrating rotators, P,Q,R branches, vibration of polyatomic molecules, normal mode of vibrations. Raman Spectroscopy: Classical and quantum theories, pure rotational Raman spectra of linear molecules, vibrational Raman spectra, mutual exclusion principle, polarization of the light and Raman effect, depolarization of Raman lines.

UNIT III

Electronic Spectra Electronics Spectra: Electronic spectra of diatomic molecules, vibrational course structure, and rotational fine structure of electronic band, the Frank-Condon principle, intensity of vibrational electronic band, dissociation energy, organic charge transfer complexes, the Fortrat diagram.

Unit IV

Nuclear Magnetic Resonance Spectroscopy: Basic principles of NMR, theory of nuclear magnetic resonance, spin lattice relaxation, spin-spin relaxation, experimental techniques chemical shift, the d-scale of chemical shift, the origin of shielding constant, pattern of coupling, origin of spin-spin coupling, the nuclear overhauser effect.

Books Suggested:



3. Principles of Physical Chemistry, Puri, Sharma andPathania, Vishal Pub.


4. Introductory Quantum Chemistry, A.K. Chandra, Tata McGraw Hill.

5. Quantum Chemistry, I.M. Levine, Prentice Hall.

6. Quantum Mechanics, M.L. Strause, Prentice – Hall

7. Quantum Chemistry, J. P. Lowe andK. Peterson, Academic Press (2005).

8. Theoretical Chemistry, Samual Glasstone Affiliated East-West Press.

9. Molecular Quantum Mechanics, P.W. Atkins andR.S. Friedman, 3rd Ed. Oxford University Press

(1997).

10. Chemical Kinetics Methods, C. Kalidas, New Age International

11. Chemical Kinetics, K.J. Laidler, McGraw Hill.

12. Modern Spectroscopy, J.M. Hollas, John Wiley.

13. Chemical Applications of Group Theory, F.A. Cotton.

14. Introduction to Molecular Spectroscopy, G.M. Barrow, McGraw Hill.

15. Basic Principles of Spectroscopy, G.M. Barrow, McGraw Hill.

16. Fundamentals of molecular spectroscopy, C. N. Banwell, Tata Macgraw Hill.

17. Physical Methods in Chemistry, R.S. Drago, Saunders College.


M.Sc. Chemistry Semester-II Inorganic Chemistry Lab–II

Paper No. CH510C Credits: 0408 Hrs /week External Marks: 75Total: 120 Hrs Internal Marks: 25

Duration of Exam: 08 Hrs

1. Quantitative Inorganic Analysis

a) Separation and determination of two metal ions such as (25 Marks)

i) Silver- Copper,

ii) Copper-Nickel,

iii) Copper-Zinc,

iv) Nickel-Zinc,

v) Copper-Iron Involving volumetric and gravimetric methods.

b) Determination by Cerimetry (20 Marks)

i) Ferrous,

ii) Oxalate,

iii) Nitrite

2. Viva-Voce (15 Marks)

3. Note Book (15 Marks)

Note: 1. New experiment(s) related to the theory paper syllabus can also be performed in addition to

the above list of experiments.

2. Depending on the availability of chemicals/instruments etc., any similar experiment can also be performed as substitute from the above list.

Books Suggested

1. Applied Analytical Chemistry: O.P. Vermani.

2. A Text Book of Macro and Semi-micro Quantitative Analysis, A.I.Vogel, Orient Longman.

3. A Vogel's Text Book of Quantitative Inorganic Analysis, J. Bassett, R.C. Denney, G.B. Jaffery and J. Menaham, Longman, London.

4. Advanced Inorganic Analysis, Aggrawal, Keemti Lal, Pragati Prakashan, Meerut


M.Sc. Chemistry Semester-IIOrganic Chemistry Lab. - II


1. Qualitative Analysis (20 marks)

Analysis of an organic mixture containing two solid components using HCl/NaOH and checking purity of individual component using TLC. IR spectra to be used for functional group identification.

2. Organic synthesis (25marks)

Two Step Preparations:

1. Sym-tribromobenzene from aniline2. 2,4-dinitrophenylhydrazine from chlorobenzene

3. 2,5-dihydroxy acetophenone from hydroquinone

4. Benzanilide from Benzophenone

Purification after first step should preferably be done by using recrystallization or column

chromatography.

Note- Department can opt any other similar two step preparation depending upon the material

available.

3. Viva-voce (15 marks)

4. Note book/Practical file (15 marks)

Books Suggested

1. Experiments and Techniques in Organic Chemistry, D. Pasto, C. Johnson and M. Miller, Prentice Hall.

2. Macroscale and Microscale Organic Experiments, K.L. Williamson, D.C. Heath.3. Systematic Qualitative Organic Analysis, H. Middleton, Adward Arnold.4. Handbook of Organic Analysis-Qualitative and Quantitative, H. Clark, Adward Arnold.5. Vogel’s Textbook of Practical Organic Chemistry, A.R. Tatchell, John Wiley.6. Advanced practical chemistry, Jagdamba, Yadav and shrivastava, Pragati Prakasan.7. Advanced organic practical chemistry, J.N.Gurtu and R. Kappor, S. Chand.8. Advanced practical organic chemistry, N.K. Vishnoi, Vikas Publishing House.9. Organic Analytical Chemistry by Jag Mohan, Narosa Publishing House.10.


M.Sc. Chemistry Semester-II Physical Chemistry Lab-II


1.Surface TensionDetermine the surface tension of given organic solvents.Study the effect of soap concentration on the lowering of surface tension of water.Compare the cleansing powers of two detergents provided to you.

2.pH-metryDetermine the strength of strong acid by pH-metric titration with strong base.Determine the strength of weak acid by pH-metric titration with strong base.Determine the dissociation constant of acetic acid using pH-meter.

3.Distribution LawDetermine the partition coefficient of iodine for distribution between chloroform and water.Determine distribution coefficient of ammonia between chloroform and water. Determine the formula of the complex formed between copper (II) ion and ammonia using distribution method.

4.PolarimetryStudy the variation of angle of optical rotation with the concentration of any optically active substance (sucrose or glucose) and thereafter determine the unknown concentration of the same substance in given solution. Determine the specific and molecular rotation of sucrose or glucose at a number of concentrations.Study the kinetics of inversion of cane-sugar (sucrose) in presence of an acid.

5.RefractometryDetermine the refractive index of simple organic liquids. Determine the refractivity and molar refractivity of some organic liquids.Determine the molar refractivities for CH2, C, H and Cl.Study the variation of refractive index with concentration for KCl solution and thereafter determine the unknown concentration of given KCl solution.

Note: Any experiment can be introduced in the practical class on the basis of availability of instruments/chemicals.Experiment Marks: 45Lab record and Viva-voce Marks: 15+15Books Suggested: 1. Yadav J.B., Advanced Practical Physical Chemistry, 29th Edition,Krishna Prakashan Media(P)Ltd. U.P., Noida.2. Khosla, B.D., Garg, V.C., Gulati, A., Senior Practical Physical Chemistry, 11th edition, Pubs: R.Chand & Co., New Delhi (2002). 3. Practical Physical Chemistry, A.M. James and F.E. Prichard, Longman.4. Findley’s Practical Physical Chemistry, B.P. Lavitt, Longman.5. Practical Physical Chemistry, S.R. Palit and S.K. De, Science.6. Experimental Physical Chemistry, R.C. Das and B. Behera, Tata McGraw Hill.


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