chromatography data system: expand to the enterprise
DESCRIPTION
Discusses the tools for expanding Chromeleon Chromatography Data System from a standalone workstation to a networked installation in your entire enterprise Learn more: http://www.thermoscientific.com/en/about-us/general-landing-page/chromeleon-resource-center.html?ca=chromeleonTRANSCRIPT
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The world leader in serving science
Streamline Your Laboratory
Thermo Scientific Dionex Chromeleon CDS Seminar
[Enter location and date here]
Expand to the Enterprise
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Contents
• Introduction• Network Architecture• Centralized Management• Operational Security• Enterprise Tools
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Introduction
• In laboratory often each instrument is controlled by its own software, especially for more sophisticated instruments like a mass spectrometer (MS)
• This has some disadvantages:• Analysts have to learn multiple software packages
• All actions need to be done on the computer next to the instruments
• Maintenance of multiple software packages
• No central data storage
• Solution: One Chromatography Data System (CDS) for the entire laboratory
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Thermo Scientific Chromeleon 7 CDS Streamlines Chromatography
For your entire enterprise
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Network Architecture
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Key Features for an Enterprise Environment
• Networking capabilities• Central data storage
• Choice of database
• Acquiring data to a central Data Vault
• Network failure protection
• Multiple Instrument Control• Instruments from different vendors
• Centralized Administration• License management, license server
• User management
• Security• User management, access control
• Electronic signatures
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Key Features for an Enterprise Environment
• Archiving• Transfer of data to a long term archive
• Backup• Securing installation and configuration data
for emergency restore
• Qualification• Installation, Operational and Performance
Qualification
• Both Software and Instruments
• Integration• LIMS, ELN
• Custom tools
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Chromeleon CDS Domain
Network Capabilities - Client/Server Architecture
LC
LaboratoryWorkstation
IC
Stand-AloneWorkstation
Remote Clientor TS Client
File/Database Server
Citrix / WTS Server
Firewall
InternetMobile Client
LaboratoryWorkstation LC/MS
InstrumentController
Chromeleon Domain Controller (CDC)
VPN
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Centralized Management
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Centralized Management – Administration Console
• Centralized management of entire CDS from one location• Easy administration of
• Licenses
• Scheduler
• User accounts
• Discovery
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Administration Console – License Manager
• Immediate overview of all licenses• Easily reassign licenses, for example when relocating
modules or instruments
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Administration Console - Scheduler
• Automatically move data by combining powerful injection queries with the Scheduler
• Easily organize your system
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Administration Console – User Management
• Comprehensive user management tools to define what users can change and/or access
• Ensures integrity and security of your data
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Administration Console - Discovery
• Easy installation and configuration of enterprise installation: Simply enter Discovery Service location on each PC in Chromeleon Domain
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Administration Console - Discovery
• All computers in the Chromeleon Domain are automatically connected and configured
• Automatically connects: • Data Vaults
• Data Vault services
• User database
• Instruments
• Instrument Controllers
• Distributes settings for:• User management
• Instrument & Client licensing
• Scheduler (archiving tool)
• Custom ePanels
• User profiles
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Operational Security
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Operational Security
• Ensure no data loss due to server crash or network failure• After major server crash, any data stored there can be
restored from backup tapes / images (IT responsibility)• Ensure operation even if the network is down
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Operational Security – Ensuring Operation
• Ensure software license is available• License information cached on all computers and available for 7 days
• Ensure users can logon• Encrypted user database is cached locally
• Ensure users can continue working• Secure XVault™ infrastructure
• Keep instruments running
• Create and run new sequences
• Keep data generated during network failure accessible for processing
• Ensure no loss of data being generated at point of network failure• Network Failure Protection
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Typical Chromeleon Enterprise CDS Installation
• Chromatography Instruments are controlled by an Instrument Controller computer.
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Remote Client
Instrument Controller with XVault
Central Server
XVault
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Typical Chromeleon Enterprise CDS Installation
• Chromatography data is stored in a Data Vault on a central server.
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Remote Client
Instrument Controller with XVault
Central Server
XVault
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Typical Chromeleon Enterprise CDS Installation
• Remote Clients can control the Instruments in the network.• Remote Clients can access the data in the network.
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Remote Client
Instrument Controller with XVault
Central Server
XVault
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Chromeleon CDS - Creating a Sequence
• Sequences are created directly in the network Data Vault.• Sequences are visible and editable from everywhere in the
network.
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Remote Client
Instrument Controller with XVault
Central Server
XVault
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Chromeleon CDS - Preparing to Start Sequence
• When the sequence is put into the Queue, it is transferred to the secure XVault on the Instrument Controller.
• The sequence is visible and editable from everywhere in the network.
Remote Client
Central Server
Instrument Controller with XVault
XVault
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Chromeleon CDS - Running Sequence
• When started the sequence runs locally on the Instrument Controller, and data is synchronized with central server.
• The sequence including data is visible and editable from everywhere.
XVault
Remote Client
Instrument Controller with XVault
Central Server
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Chromeleon CDS - Network Failure
• When the network fails acquisition continues on the secure XVault.
• The sequence including data is visible and editable from the Instrument Controller.
Remote Client
Instrument Controller with XVault
Central Server
XVault
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Chromeleon CDS - Application Availability
• During network failure it is possible to create and start new sequences from the XVault.
Remote Client
Instrument Controller with XVault
Central Server
XVault
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Chromeleon CDS - Network Recovery
• When the network is back, data will be transferred back to the central Data Vault.
• The sequence is again visible and editable from everywhere in the network.
Remote Client
Instrument Controller with XVault
Central Server
XVault
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Enterprise Tools
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Integration to 3rd Party Software
• Interface with any:• LIMS
• SDMS
• ELN
• or any other 3rd party software package!
• A Software Development Kit (SDK) provides a set of development tools that allows users to create special applications which require direct access to the data.• An example is creating an interface to a LIMS platform to automatically
process worklists in the CDS and for the final result to be posted back into the LIMS
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Support Documentation
• Complete set of documentation available:• General
• Project Specific
• Database Installation & Configuration
• Software Installation & Configuration
• Installation Checklists
• These documents are designed to cover all compliance & regulatory requirements
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Summary
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Summary
• Streamline your laboratory - use one CDS to control all chromatography instruments and process and report all data:• Reduced training effort for the laboratory staff – one single software
package instead of several
• Operate all your chromatographic instruments, including MS, using one software
• Highest laboratory uptime and prevention of data loss through Operational Security and secure XVault infrastructure
• Lower operating cost with centralized management of one single software
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Summary – Bringing It All Together
Discovery
Security
AdminConsole
All the tools you need to expand your CDSto the enterprise level!
Network
XVault
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Thank You!
Any Questions?