Classification of sclerodermas

• Localized sclerodermas

• Morhpea• Linear scleroderma

Morphea

Linear scleroderma

Classification of sclerodermas

• Localized sclerodermas• Morhpea

• Linear scleroderma

• Overlap syndromes (with SLE, myositis)

Classification of sclerodermas

• Localized sclerodermas• Morhpea

• Linear scleroderma

• Overlap syndromes (with SLE, myositis)

• Scleroderma-like syndromes• Eosinophilic fasciitis

• Scleromyxedema

• Chronic graft versus host

• Drug-induced (bleomycin, toxic oil, tryptophan)

Eosinophilic fasciitis(early)

Eosinophilic fasciitis(late)

Scleromyxedema

Classification of sclerodermas

• Localized sclerodermas• Morhpea

• Linear scleroderma

• Overlap syndromes (with SLE, myositis)

• Scleroderma-like syndromes

• Systemic sclerosis• Diffuse cutaneous scleroderma• Limited cutaneous scleroderma• CREST syndrome

Diffuse vs Limited Scleroderma-- Definitions

• Diffuse cutaneous scleroderma:– Thick skin distal AND proximal to elbows and knees,

with or without the face (widespread, or diffuse, skin thickening).

• Limited cutaneous scleroderma:– Thick skin distal, but NOT proximal, to elbows and

knees, with or without the face (limited skin thickening)

Thick skin of torso

(diffuse scleroderma)

Thick skin of fingers and hands(limited scleroderma)