clinical and radiographic analysis of an optimized rhbmp- 2 formulation as an autograft replacement...

5
Clinical and Radiographic Analysis of an Optimized rhBMP-2 Formulation as an Autograft Replacement in Posterolateral Lumbar Spine Arthrodesis by John R. Dimar, Steven D. Glassman, J. Kenneth Burkus, Philip W. Pryor, James W. Hardacker, and Leah Y. Carreon J Bone Joint Surg Am Volume 91(6):1377-1386 June 1, 2009 ©2009 by The Journal of Bone and Joint Surgery, Inc.

Upload: gwenda-flynn

Post on 21-Jan-2016

215 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Clinical and Radiographic Analysis of an Optimized rhBMP- 2 Formulation as an Autograft Replacement in Posterolateral Lumbar Spine Arthrodesis by John

Clinical and Radiographic Analysis of an Optimized rhBMP-2 Formulation as an Autograft Replacement in

Posterolateral Lumbar Spine Arthrodesis

by John R. Dimar, Steven D. Glassman, J. Kenneth Burkus, Philip W. Pryor, James W. Hardacker, and Leah Y. Carreon

J Bone Joint Surg AmVolume 91(6):1377-1386

June 1, 2009

©2009 by The Journal of Bone and Joint Surgery, Inc.

Page 2: Clinical and Radiographic Analysis of an Optimized rhBMP- 2 Formulation as an Autograft Replacement in Posterolateral Lumbar Spine Arthrodesis by John

Comparison of the improvement in mean Oswestry Disability Index (ODI) scores in the iliac crest bone-graft (ICBG) and recombinant human bone morphogenetic protein-2 (rhBMP-2) matrix

groups at each follow-up interval.

John R. Dimar II et al. J Bone Joint Surg Am 2009;91:1377-1386

©2009 by The Journal of Bone and Joint Surgery, Inc.

Page 3: Clinical and Radiographic Analysis of an Optimized rhBMP- 2 Formulation as an Autograft Replacement in Posterolateral Lumbar Spine Arthrodesis by John

Comparison of the mean SF-36 physical component summary (PCS) scores in the iliac crest bone-graft (ICBG) and recombinant human bone morphogenetic protein-2 (rhBMP-2) matrix

groups.

John R. Dimar II et al. J Bone Joint Surg Am 2009;91:1377-1386

©2009 by The Journal of Bone and Joint Surgery, Inc.

Page 4: Clinical and Radiographic Analysis of an Optimized rhBMP- 2 Formulation as an Autograft Replacement in Posterolateral Lumbar Spine Arthrodesis by John

Comparison of the mean back pain scores in the iliac crest bone-graft (ICBG) and recombinant human bone morphogenetic protein-2 (rhBMP-2) matrix groups.

John R. Dimar II et al. J Bone Joint Surg Am 2009;91:1377-1386

©2009 by The Journal of Bone and Joint Surgery, Inc.

Page 5: Clinical and Radiographic Analysis of an Optimized rhBMP- 2 Formulation as an Autograft Replacement in Posterolateral Lumbar Spine Arthrodesis by John

Comparison of the mean leg pain scores in the iliac crest bone-graft (ICBG) and recombinant human bone morphogenetic protein-2 (rhBMP-2) matrix groups.

John R. Dimar II et al. J Bone Joint Surg Am 2009;91:1377-1386

©2009 by The Journal of Bone and Joint Surgery, Inc.