Clinical Challenges in the Patient With Relapsed Multiple Myeloma

Multiple MyelomaHow to decide what to do at first relapse?

Early Relapsed Multiple MyelomaCarfilzomib and Pomalidomide

Relapsed Multiple Myeloma Try to use therapies for as long as they

work.

Early Relapsed Multiple MyelomaDuration of Therapy

Duration of Therapy Try to treat for at least 8 cycles or to best

response and not until progression.

Duration of Therapy Patients with short second remission or

high-risk disease should be treated continuously until progression.

Early Relapsed Multiple MyelomaRole and Timing of 2nd HDT/ASCT

2nd HDT/ASCT at RelapseUse for patients who had at least 3-year

remission after first HDT/ASCT, and follow by alternative maintenance therapy to

what they had previously.

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