“clinical study on snake bite syndrome, species correlation and asv dose requirement” dr. ann...

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“Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra P.O, Karimganj Dist., Assam – 788727 GPS coordinates: 24*25'55.78"N 92*19'51.33"E

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Page 1: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

“Clinical study on snake bite syndrome, species correlation and ASV dose requirement”

Dr. Ann MiriamMakunda Christian Leprosy and general Hospital

Bazaricherra P.O,Karimganj Dist.,Assam – 788727

GPS coordinates:24*25'55.78"N92*19'51.33"E

Page 2: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

Location

GPS coordinates:24*25'55.78"N92*19'51.33"E

Page 3: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

Brief Hospital Statistics 2011-12

Total OP: 91,242Total IP: 9471

Brief statistics of Karimganj DistrictPopulation: 12 Lakhs

Deaths due to snake bites : 0*Oujha : 2

*According to NRHM data

Page 4: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

LOWAIRPOA BLOCKPopulation : 1 Lakh

Bazaricherra Gram panchayatPopulation : 12 thousand

A survey was done and it was noticed that there were only 2 deaths by snake bites in the last 15

years.

Page 5: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

Common Poisonous snakes in Makunda

Red-necked keelbackRhabdophis subminiatus

Banded kraitBungarus fasciatus

Page 6: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

Other venomous snakes identified by the local people

• White lipped pit-viper• Greater black Krait• Monocled Cobra

Page 7: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

Oujha

Page 8: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

Probable cause of CellulitisTreatment by Oujha – Cutting of snake bitten area by using a blade and applying local herbal medicine

Page 9: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

Snake bites last year = 10Venomous bites = 1

Non – venomous bites = 9Mainly Hemotoxic = 1

Dead snakes brought – Nil

Page 10: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

OUTCOMES

Patients requiring mechanical ventilation – NilPatients requiring hemodialysis – Nil

Deaths - Nil

Page 11: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

FACILITIES AVAILABLE

Bleeding timeClotting time

Whole blood transfusionHemodialysis facilities – Machine available (Not in use)

Mechanical ventilators – yesHigh Dependency area

Page 12: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

Blood investigations doneHemogram

Serum CreatinineBlood Sugar

BT / CTPlatelet count

ECG

Page 13: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

INDICATION FOR ASV ADMINISTRATION

Prolonged BT/ CTAdrenaline given when there is sign of anaphylaxis

Initial dose of ASV 8 – 10 vialsDuration of administration 4 – 6 hoursTest used for monitoring response -

Whole Blood Clotting TimeTime of measurement of coagulation parameters –

3 times in a day

Page 14: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

ADMINISTRATION OF REPEAT DOSE OF ASV

Not given so far

ADMINISTRATION OF CONTINUOUS LOW DOSE OF ASV

Not given so far

Page 15: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

CEILING DOSE

No experience

USE OF NEOSTIGMINE

No experience

Page 16: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

INDICATION FOR ANTIBIOTIC THERAPY

Cellulitis

COMMON ANTIBIOTICS USED

Ampicillin and Ampicloxacillin

Page 17: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

PATIENTS ADMITTED IN

High Dependency area

PATIENTS REFERRED FOR

No referrals so far

Page 18: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

COMPANY OF ASV PURCHASE

Haffkine

STOCK OF ASV

10 Vials

Page 19: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

Why are snake bites so un-common in Makunda?• Thickly populated location• Venomous snakes present• Dense forests• Frequent floods

Page 20: “Clinical study on snake bite syndrome, species correlation and ASV dose requirement” Dr. Ann Miriam Makunda Christian Leprosy and general Hospital Bazaricherra

THANK YOU