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CMIC CO., LTD.CMIC CO., LTD. CorporateCorporate PresentationPresentation
February, 20February, 201010
Kazuo NAKAMURAKazuo NAKAMURA
Chairman and CEOChairman and CEO
This presentation contains future financial projections. While such projections were prepared in good faith by our management, no assurance can be made regarding future events. Therefore, such projections cannot be considered a reliable predictor of future operating results, and this information should not be relied on as such. In the view of our management, the information was prepared on a reasonable basis, reflects the best currently available estimates and judgments, and presents, to the best of our management‘s knowledge and belief, the expected course of action and our expected future financial performance. However, this information is not fact and should not be relied upon as being necessarily indicative of future results, and you are cautioned not to place undue reliance on this information.The estimates and assumptions underlying the projections involve judgments with respect to, among other things, future economic, competitive, regulatory and financial market conditions and future business decisions that may not be realized and are inherently subject tosignificant business, economic, competitive and regulatory uncertainties, all of which are difficult to predict and many of which are beyond our control. Accordingly, there can be no assurance that the projected results would be realized or that actual results would not differ materiallyfrom those presented in the financial information.We do not intend to update or otherwise revise the prospective financial information to reflect circumstances existing since its preparation or to reflect the occurrence of unanticipated events, even in the event that any or all of the
underlying assumptions are shown to be in error. Furthermore, we do not intend to update or revise the prospective financial information to
reflect changes in general economic or industry conditions.
2
Contents
Business EnvironmentOur Business
Performance
CRO (Contract Research Organization) SMO (Site Management Organization)
CMO (Contract Manufacturing Organization) CSO (Contract Sales Organization)
IPD (Intellectual Property Development)
3
Business Environment
4
人口
1万
人あ
たり
の発
症率
0
5
10
15
20
25
30
35
40
1950 55 60 65 70 75 80 85 90 95 2000 05 10 15 20 25 30 35 40 45 2050
65歳以上人口の割合
日本
イギリス
イタリア
フランス
ドイツ
カナダ
アメリカ
韓国
中国
(高齢化率、総人口に占める65歳以上人口の割合、%)
(出所)人口統計資料集2008(国立社会保障・人口問題研究所)、World population prospects, 2008Revision(UN)
(暦年)
(推計)
日本
アメリカ
カナダ
フランス イタリア
ドイツ
05年
アメリカ 12.4%
イギリス 16.1%
ドイツ 18.9%
フランス 16.5%
イタリア 19.6%
韓国 9.3%
中国 7.6%
日本 20.2%韓国
イギリス
中国
65歳以上人口の割合65歳以上人口の割合
JapanJapan
GermanyGermany
ItalyItalyFranceFrance
UKUK
USAUSA
CanadaCanada
KoreaKorea ChinaChina
Accelerating Aging Society
Proportion of the global population of 65 and over
% of
population
65 and over
Source: Latest demographic statistics 2008/ Institute of Population Problems, Ministry of Health and Welfare, World population prospects,2008 Revision(UN)
CY
Estimate
5
Global Pharma Market
59.764.7
67.763.7
65.7
47.5
55.9
73.6
88.5
66.2
0.0
100.0
200.0
300.0
400.0
500.0
600.0
700.0
800.0
2003 2004 2005 2006 2007
South America
AAA
Japan
Europe
US
(billion $)
Source: JPMA DATA BOOK 2009AAA: Asia, Africa and Oceania excluding Japan
499.0559.9 604.5
648.9714.8
• Market has grown and is expected to grow in the near future• Asian market, including Japan, is the most promising area
6
Sales and R&D Expenditures Japanese Pharma(billion yen)
Source:Japan Pharmaceutical Manufacturers Association (JPMA) DATA BOOK 2009
0
100
200
300
400
500
600
2003 2004 2005 2006 2007
40
60
80
100
120
Average Sales per company (Major 10 Japanese pharma)
Average R&D expenditures per company (Major 10 Japanese pharma)
Both Sales and R&D Investment of Japanese Top 10 Pharma have been increasing
(billion yen)
7
Our Business
8
CMIC Group
• Established in 1985, Tokyo– Net Sales: 28.7billion yen (Sep 2009) or US$320 million – No. of Employees: 2759 (Sep 2009)– No. of Domestic Offices: 18– No. of Overseas Offices: Korea, China, Taiwan, Singapore, US, Brazil
• Services– CRO (Contract Research Organization)– SMO (Site Management Organization)– CMO (Contract Manufacturing Organization)– CSO (Contract Sales Organization)– IPD (Intellectual Property Development)
New Business Model :
Pharmaceutical Value CreatorNew Business Model :
Pharmaceutical Value Creator
9
History Highlights I
• 1992 Kazuo Nakamura, CEO, started the operation of CMIC as the 1st Japanese CRO
• 1994 Monitoring Business started• 1996 CMIC established a joint venture as the 1st Korean CRO• 1996 SMO business started• 1997 CMIC North America (Toronto) branch established• 1998 CMIC Europe (Manchester) branch established• 1998 CMIC Korea Co., Ltd. established• 2000 CSO business started• 2001 CMIC China established• 2002 Listed on the JASDAQ market • 2003 Healthcare Information Service business started
(CMIC and NTT DATA established a joint venture)
10
History Highlights Ⅱ
• 2004 IPD business started (L-FABP diagnostic for predicting the progression of renal diseases)
• 2005 CMO business started• 2005 Listed on the Tokyo Stock Exchange 1st section• 2005 CMIC and Fuji Film established Fujifilm CMIC Healthcare • 2006 CMIC BRASIL PESQUISAS CLÍNICAS LTDA. established • 2006 CMIC Asia-Pacific, Pte. Ltd. established• 2007 CMIC-VPS Corporation acquired (NJ U.S.A)• 2008 Obtain Orphan Drug Development and Marketing Rights
in Japan (Human hemin)• 2009 Sign License Agreement on L-FABP diagnostic with ROCHE • 2010 April
Ownership transfer of Shizuoka Plant from DAIICHI SANKYOPROPHARMA Co., Ltd.
11
Domestic Offices
Kagoshima
Kumamoto
Fukuoka
Osaka
Okayama
Nagoya
Shizuoka
Toyama
Hokkaido
Tokyo
Takamatsu
Hiroshima
Kanazawa
Sendai
Kobe
MatsuyamaOita
Nagasaki
Number of branches/offices: 18
12
CMICCMIC--VPSVPS
ShanghaiShanghaiTaiwanTaiwan
CMIC AsiaCMIC Asia--PacificPacific
CMIC (Beijing)
CMIC KoreaCMIC Korea
CMIC CMO KoreaCMIC CMO Korea
CMIC Brazil
Beijing and Shanghai, ChinaBeijing and Shanghai, ChinaSeoul, KoreaSeoul, Korea
New Jersey, USNew Jersey, USPorto Porto AlegreAlegre, Brazil, Brazil
SingaporeSingaporeTaipei, TaiwanTaipei, Taiwan
8 offices in 6 CountriesOverseas Offices
13
CMIC’s Unique Business Model - Pharmaceutical Value Creator -
Basic Basic researchresearch
Preclinical Preclinical trialtrial
Clinical trialClinical trialPhasePhase II
Clinical trialClinical trialPhasePhase IIII
Clinical trialClinical trialPhasePhase IIIIII
Application Application for approvalfor approval
ManufacManufac--turingturing MarketingMarketing
Pharmaceutical CompanyPharmaceutical Company
CROPreclinical trial
CSOCSOContract Sales Organization
CROCRO Contract Research OrganizationContract Research Organization・
IND data monitoring・
Data management, statistics analysis・
Application documents preparation SMOSMO Site Management OrganizationSite Management Organization・
Site Management Office and IRB administration・
SOP preparation・
Clinical Research Coordinator
CMOCMO Contract Manufacturing Organization, Manufacturing of Investigational Drug
IPDIPDIntellectual Property
Development
14
CMIC Group Business ModelCMIC Group
HVCHVC Healthcare Value CreatorHealthcare Value Creator
for Patients, Hospitalsfor Patients, Hospitals
PVCPVC Pharmaceutical Value CreatorPharmaceutical Value Creator
for for PharmaPharma CompaniesCompanies
CROCROContract Research Contract Research
OrganizationOrganization
CMOCMOContract Manufacturing Contract Manufacturing
OrganizationOrganization
CSOCSOContract Sales Contract Sales OrganizationOrganization
HealthcareHealthcareInformation ServiceInformation Service
SMOSMOSite Management Site Management
OrganizationOrganization
IPDIPDIntellectualIntellectual
Property Property DevelopmentDevelopment
15
程度
700
390
199
2660
?
700
1400
0
200
400
600
800
1000
1200
1400
1600
Japanese Market
Global Market
Source preclinical: Mitsubishi Research CRO・SMO:JCROA, JSMOACMO:Yano Research Institute CSO: MIC Research , Mitsubishi Research
Basic research
Basic Basic researchresearch Preclinical trialPreclinical trialPreclinical trial Clinical trialClinical trialClinical trial ManufacturingManufacturingManufacturing MarketingMarketingMarketingApplication
for approval Application Application for approvalfor approval
Preclinical CRO (including drug discovery)
CRO、SMO CMO CSO
Market size of service industries for pharmaceutical industry
(billion yen)
16
Pharmaceutical Value Creator -
CMIC’s unique business model -
PVC is our unique business model providing comprehensive services for pharmaceutical value chain PVC includes CRO, SMO, CMO and CSO
The largest CRO and SMO in Japan
Track Record in Multinational Clinical TrialsCMIC provides services for one of the largest global pharma as its preferred vendor
Intellectual Property Development CMIC accumulates IP and knowhow of applying it to healthcare and other pharmaceutical businesses for future use
Promoting eClinical Trials ( Data digitization)
CMIC’s Competitive Edge
17
CRO (Contract Research Organization)
18
156 241389
501614 710
831955 1025 1130
514500
403
286221
85
8
31
482
0
200
400
600
800
1,000
1,200
1,400
1,600
1,800
Dec.2000 Dec.2001 Dec.2002 Dec.2003 Dec.2004 Dec.2005 Dec.2006 Dec.2007 Dec.2008 Dec.2009
Affiliated companiesJCROA members
156249
420586
835
1,437
996
1,234
69%
40%
Growth rate 60%
42%
19%
24%
16%
(¥ 100 mil)
Source:Japan CRO Association excluding pre-clinical (2000-2003)
Growth Rate: JCROA members + affiliated companies
CRO Market in Japan Total sales of CROs and their affiliated companies
1,5397%
1,6306%
19
Clinical patientClinical patient
Clinical siteClinical sitePharmaceuticalPharmaceuticalcompanycompany
Application of clinical trial
Site monitoring /Auditing
Case report /Adverse event report
Contract
・Clinical Research CoordinatorObtain Informed ConsentTake care of clinical patients etc.
Inform To give consent
Structure of Clinical Trial(CRO&SMO)
IRBIRB・Investigator
CROCRO SMOSMO
20
Largest No. of CRAs in Japan
• CRAs : over 700 • Protocols: 195
(Oct 1997 - Sep 2009)
Sensory Organs1%
Cardiovascular6%
Non TherapeuticPurpose
3%Diagnostic agents
1%
Medical Devices2% CNS
19%Other11%
Oncology3%
Infectious Disease7%
Metabolism16%
Hematology8%
Skin2%
Respiratory Organs2%
Gastro Intestinal3%
Endocrinology3%Urology
4%
Biologics5%
Antiallergic Agents3%
Therapeutic Areas
21
SMO (Site Management Organization)
22
Site Support Institute Co., Ltd. (SSI)
• Number of employees: 695CRC: 440 SMA: 98
• Protocol performances: 1,505Ongoing: 383
• Number of sites: 1,538University Hospitals: 47Hospitals: 593Clinics: 898
• Number of branches/offices: 18Kagoshima
Kumamoto
Fukuoka
Osaka
Okayama
Nagoya
Shizuoka
Toyama
Hokkaido
Tokyo
Takamatsu
Hiroshima
Kanazawa
Sendai
Kobe
Matsuyama
Oita
Nagasaki
The largest SMO in Japan
(As of Oct. 2009)
(As of Dec. 2009)
(As of Dec. 2009)
23
Strategic Synergy – CMIC and SSI –
Strategic synergy between CMIC and SSI contributes to enhancing
the speed and quality of clinical trials
CMIC serves as a platform of clinical trial businesswith enhanced strategic advantages
24
Strategic Synergy – CMIC and SSI – Advantages Over Competitors
0
50
100
150
200
250
300
2008/6 2008/7 2008/8 2008/9 2008/10 2008/11 2008/12
Total number of cases Planned number of cases
(Number of cases)
Achieved all the target patients two months earlier than planned
Early Achievement of All the Patient Enrolment- Perennial Allergic Rhinitis -
25
0
5,000
10,000
15,000
20,000
25,000
2007/9 2008/9 2009/9
CMIC CRO・SMO Sales and Backlog
0
5,000
10,000
15,000
20,000
25,000
2007/9 2008/9 2009/9
BacklogSales
Steady growth in sales and backlog
↑↑55% % increaseincrease
↑↑4% 4% increaseincrease ↑↑19% 19%
increaseincrease
↑↑11% 11% increaseincrease
SMOCRO
(million yen) (million yen)
26
Multinational Study
27
0
5
10
15
20
25
30
35
1999 2000 2001 2002 2003 2004 2005 2006 2007
Multinational studies Asian studies
Multinational & Asian Studies - Rapid Increase in Number-
Data presented by Hidetoshi Syuto, Astellas Pharma Inc.
(Number of Global Studies)
28
Pioneering CRO in the Asian market
Abundant experience in multinational studies
Speed of recruiting clinical patients for multinational studies
Selected as a preferred vendor by a global pharma
CMIC’s Advantages Multinational &Asian Studies
CMIC maintains the leading position in Multinational and Asian studies
29
Offices in Asia for Multinational & Asian Studies
CMIC Co., Ltd. Japan
No. of members : 60
CMIC Korea Co., Ltd.No. of members : 60
CMIC (Beijing) Co., Ltd. Beijing, ShanghaiR.O.C.No. of members : 20
CMIC Asia-Pacific Pte. Ltd. SingaporeTaipei TaiwanNo. of members : 10
30
CMO (Contract Manufacturing Organization)
31
April 1994 Revised Pharmaceutical Affairs Law (PAL) allowed pharmaceutical companies to outsource drug manufacturing process partlyJuly 2005 Revised PAL allowed pharmaceutical companies without manufacturing facilities to outsource the whole process of drug manufacturingManufacturing Approval → Marketing Approval
CMO - Regulatory History
Revised regulations have accelerated drug manufacturing outsourcing services
32
Cost reduction effort ・With an imminent expiry of patents on major pharmaceutical products
(Year 2010 problem)
Increase in business efficiencyTrend to enter into a manufacturing business without production facilities
(fabless company)・Reduction in facility investment・Fixed cost → variable cost・Stable supply of quality products
High-mix low-volume production・Easy to increase / decrease production volume
New formulation development・Enhance the development capacity of new drug formulation
Reasons for Pharmaceutical Companies to Rely on CMO
33
Why CMO in CMIC?
Market expansion expected Regulatory movement to accelerate outsourcing services in drug manufacturing process
Manufacturing Div. ⇒ Subsidiary Outsourcing ⇒ CMO
Establishment of PVC business model CMIC has advantages against competitive companies in that it has established a unique business model of PVC which provides comprehensive services for value chain of pharmaceutical companies
Manufacturing as a key businessManufacturing is a key business for Japanese companies to win a place in the global market
High quality / new formulation technologyCost?
34
CSOCSOmarketing / marketing /
salessales
Strategic Synergy
Physical and Physical and chemical testchemical test
CROCROdrug developmentdrug development
Investigational drug Investigational drug managementmanagement
Documents for Documents for applicationapplication
Provide comprehensive services for Provide comprehensive services for Japanese pharmaceutical companiesJapanese pharmaceutical companiesto enter into global marketsto enter into global markets
Provide comprehensive services forProvide comprehensive services foroverseas pharmaceutical companies overseas pharmaceutical companies to enter into the Japanese marketto enter into the Japanese market
Safety InformationSafety Information
CMOCMOFormulation study Formulation study ~~ manufacturingmanufacturing
Investigational drug Investigational drug managementmanagement
PromotionPromotion
35
One of the largest CMOs in Japan(Will have sales of about 13 billion yen)
Manufacturing high quality products
Capable of handling small lots of a large variety of products(Efficient production)
Upgrading formulation manufacturing technology(Technology transfer from drug manufacturers)
Enhancement of formulation development capabilities(Supporting new drug formulation design)
Synergies will be explored between CRO and CMO:(Make the most of every opportunity)
manufacturing of investigational drugs ~ clinical trials ~ manufacturing of commercial drugs
Medium Term Vision for the CMO Company
36
CMO Business
Manufacturing services include : Ointment, Cream, Gel, Lotion, Suppository, Liquid, Tooth paste etc. Manufacturing services (packaging) include : Blister package (PTP) and Strip package (SP) for Tablets, Capsules etc.
Operation since:
Sep 2006 Number of
items:
71
CMIC SS CMO Co., Ltd.
CMIC CMO Korea Co., Ltd.Manufacturing services include : Liquid for internal use, Ointment, Cream, Gel
Operation since: Aug 2005 Number of items:
30 (including items for sales)
CMIC-VPS Corporation (USA)Manufacturing services include :Tablets(uncoated and film-coated tablets), Capsules, seamless-mini CapsulesOperation since:
Dec 2007
Number of items: 22(commercial production: 2,
drug development:
17, development of other products:
3)
37
CMIC SS CMO has been showing Underlying upward trend in the number of items
0
2
4
6
8
10
12
14
16
2007/3 2008/3 2008/9 2009/9 2010/9(E)
50
55
60
65
70
75
80
85
Clients
items
CMIC SS CMO Growing Number of Items and Clients
38
132
222
298
374
0
50
100
150
200
250
300
350
400
2008/3 2008/9 2009/3 2009/9
CMIC-VPS Corporation(NJ, US)
Investigational Drug and Drug Manufacturing Sales
CMIC VPS has been showing steady growth
(million yen)
39
Manufacturing capacity:
Tablet formulations: 1.5 billion/year, Capsule formulations: 500 million capsules/year, Granule/powder formulations: 200 tons/year
Location :
1-588, Kanaya-azuma, Shimada, ShizuokaArea:
210,000㎡Commencement of operations:
1965
Overview of the Daiichi Sankyo Propharma Shizuoka Plant
40
CMIC CMO - Drug Formulations -
Source :Japan Pharmaceutical Manufacturers Association Data Book 2009
(¥100 million)
Oral solution
Ointment / Cream Suppository
External Solution
Powders / Granule
Tablet
Pill
Capsule
Injection
Injectable
powder
Aerosols
Plaster
/ Cataplasm
Others
41
CSO (Contract Sales Organization)
42
MDS Co., Ltd.MDS Co., Ltd.Medical Communication with Academic Support
Academic ServiceAdvertising & Promotion
Promotion StrategyPromotion Materials
CMIC MPSS Co., Ltd.CMIC MPSS Co., Ltd.Contract MR (Medical Representative)MR TrainingMarket Assessment
Contract Sales Organization
43
455816
1,447
1,146
0
500
1,000
1,500
2,000
2,500
2008/9 2009/9
MDSCMIC MPSS
1,901 1,962Internal
elimination
(1) MDS Good performance
MPSS High growth
Contract Sales OrganizationSales(million yen)
44
IPD (Intellectual Property Development)
45
Exclusive license in Japan Exclusive license in Japan including the right to sublicenseincluding the right to sublicense
Our Business Model - L-FABP – KIDNEY DISEASE DIAGNOSTIC AGENT
SublicenseHigh value-added service
Application for Application for clinical clinical
developmentdevelopment
PatentPatentPharmaceutical Pharmaceutical companycompany
Pharmaceutical CompanyOverseas Diagnostic Company
Clinical Laboratory Company
46
L-FABP Patent for ROCHE
CMIC and ROCHE have entered into an agreementon L-FABP diagnostic test
47
Our Business Model -Human Hemin‐
Pharmaceutical CompanyPharmaceutical CompanyCMIC CSOCMIC CSO
Exclusive license in Japan Exclusive license in Japan including the right to sublicenseincluding the right to sublicense
Orphan EuropeOrphan Europe((pharmaceutical companypharmaceutical company))
Application Application for clinical for clinical
developmentdevelopment
PatentPatent
4848
Orphan Drug Development and Marketing Rights in Japan
Press release on December 17, 2008
Human Hemin (Orphan drug)Signed a license agreement with Orphan Europe of France for drug development in Japan
Indicated for acute porphyria
49
Performance
50
0
5,000
10,000
15,000
20,000
25,000
30,000
35,000
40,000
1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010E
0
1,000
2,000
3,000
4,000
5,000
6,000
7,000
8,000
02468101214161820(%)
CMIC Performance (Consolidated basis)Sales
Operating Income
Operating Income
Ratio
SalesOperating IncomeOperating Income Ratio
New GCP in 1997
Revised Japanese PharmaceuticalAffairs Law in 2005
(million yen) (million yen)
51
50%
20%
7%
20%
3%
64%9%
7%
16%
4%
58%
10%
7%
22%
3%
Sep.2008 Sep.2009 Sep.2010
25,777 28,784 34,000
12% increase
18% increase
Sales by Operating Segments
OTHER
(million yen)
52
From PVC to HVC
Annual Sales Target in 2015 Annual Sales Target in 2015 --¥¥1100 billion00 billion--
CROConventional CRO Group of
skilled individualsWorking on
pharmaceuticaldevelopment
CROCROConventional Conventional CRO Group ofCRO Group of
skilled individualsskilled individualsWorking on Working on
pharmaceuticalpharmaceuticaldevelopmentdevelopment
Pharmaceutical
Value Creator
Contribution to growing pharma industry
PPharmaceuticalharmaceutical
VValuealue CCreatorreator
Contribution to growingContribution to growing pharmapharma industryindustry
HHealthcareealthcare
VValuealue CCreatorreator・・Patient orientedPatient oriented
healthcare serviceshealthcare services
・・Disease managementDisease management
Corporate Value= Sustainable Profit
53
Company Data
Trade Name CMIC Co., Ltd.
Established/Business initiated 1985(started as CRO in 1992)
Chairman and CEO Kazuo Nakamura
Fiscal year-end September
Business fields Parmaceutical and HealthcareCRO(Contract R&D)CMO(Contract Manufacturing)CSO(Contract Sales)SMO、Healthcare、IPD
Headquarters 7-10-4, Nishi-Gotanda, Shinagawa- ku, Tokyo
Contact Us E-mail:[email protected]:+81-3-5745-7070Fax:+81-3-5745-7077
Employees 2,759
Stock Listings First Section of the Tokyo Stock ExchangeCode Number:2309
Number of Stockholders 6,399
Issued Shares/Authorized Shares 894,957 / 2,300,000
The First and Largest Full Service CRO in Japan
Fiscal Year FY 2007 FY 2008 FY 2009 FY Sep2010 Est.
Net Sales 21,616 25,777 28,784 34,000
Operating Income 2,159 2,275 2,514 3,000
Ordinary Income 2,153 2,187 2,400 2,600
Net Income 1,198 829 1,059 1,200
Dividend※ 216 266 334 380
Dividend rate 13.7% 26.5% 27.7% 27.8%
※ CMIC’s Annual Dividend Payout Ratio target continues to set at 30%
Our position of Japanese association
【Frost & Sullivan】
2007 Best Practices Award for Competitive Strategy Leadership Award in the Japanese CRO Market.
【Japan Investor Relations Association】
JIRA IR Special Award
million yen (※yen)
Kazuo Nakamura
【Japan CRO Association】Chairman Kazuo Nakamura(CMIC)
【Japanese Association of SMO】Chairman Toshimasa Yasuda (CMIC Group)
Award
54
(yen) (yen)
1,328.23
1,579.33
1,003.94
1,205.63
1,365.27
0
200
400
600
800
1,000
1,200
1,400
1,600
1,800
2006/9 2007/9 2008/9 2009/9 2010/9E
216216
266334
38016.3% 13.7%
26.5%27.8%27.7%
0
50
100
150
200
250
300
350
400
450
500
2006/9 2007/9 2008/9 2009/9 2010/9E0%
5%
10%
15%
20%
25%
30%
35%Cash DividendsDividends Payout Ratio
【Earnings Per Share】 【
Cash dividends 】
CMICCMIC’’ss Annual Dividend Payout Ratio Annual Dividend Payout Ratio Continues to target 30% Continues to target 30%
FY2010 Forecasts –EPS/Cash Dividends –
55
Stock Chart(CMIC:TSE2309) Weekly chart of stock price range and trading volume
0
5000
10000
15000
20000
25000
30000
2008
/10/
6
2008
/10/
27
2008
/11/
1720
08/1
2/8
2008
/12/
2920
09/1
/19
2009
/2/9
2009
/3/2
2009
/3/2
320
09/4
/13
2009
/5/7
2009
/5/2
520
09/6
/15
2009
/7/6
2009
/7/2
720
09/8
/17
2009
/9/7
2009
/9/2
8
2009
/10/
1920
09/1
1/9
2009
/11/
30
2009
/12/
2120
10/1
/12
2010
/2/1
0
2000
4000
6000
8000
10000
12000
14000
16000
Trading Volume
Stock Price
Stock Prices:yen Trading Volume