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    COMPLICATIONS OFHIV/AIDS

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    HIVHuman Immunodefciency Virus

    Implies the entire course o HIVinection, rom asymptomatic inecand early symptoms to AIDS.

    A chronic condition, controllable wmedications and strict adherence ttreatment recommendations

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    AIDS

    Acquired immunodefciency syndro

    ost se!ere rom o a continuum oillnesses associated with HIV.

    I untreated, it causes slow

    de"eneration o the immune systewith the de!elopment o opportuninections and mali"nancies.

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    Causative AgentA retro!irus that inects and deple

    the #D$% &'helper lymphocytes (oo the protector o the immunesystem.

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    Body fuids knon tot!ans"it HIV

    )loodVa"inal secretions

    Semen

    )reast mil*

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    HIV is t!ans"itted #y$

    In+ection o blood or bloodcomponents.

    Seual contact (!a"inal or analintercourse, oral se-

    erinatally (rom an inected moththe child-

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    COMPLICATIONS

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    Candidiasis

    #ommon un"al inection that can be treateantiun"al medications ollowin" a simple eamination. #andidiasis is a common opportinection in people with HIV. It is an inection cby a common type o yeast (or un"us-

    candida. &his yeast is ound in most pebodies. A healthy immune system *eeps it control. #andida usually inects the mouth, tor !a"ina.

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    #er!ical #ancer

    #er!ical cancer is an abnormal "ro cells in the cer!i that can bethreatenin". It de!elops ollo

    cer!ical dysplasia. #er!ical cancconsidered an AIDS'defnin" illneopportunistic inection.

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    Co%%idioido"y%osis

    #ommon un"al inection that can to pneumonia i let untreated.

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    C!y&to%o%%osis

    0un"al inection that oten ethrou"h the lun"s, quic*ly spreadithe patient/s brain, oten leadincryptococcal menin"itis.

    untreated, this un"al inection is oatal.

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    C!y&tos&o!idiosis

    &his diarrheal disease oten becochronic2 it is characteri3ed by sediarrhea and abdominal crampin".

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    Cyto"ega'ovi!us&his common "lobal !irus a4ects most adults

    their lietime. In HIV5AIDS patients, it oten prwith eye or "astrointestinal inections. 6ormhides out in the body. &his is not a problem opeople because a healthy immune system cancontrol it. Howe!er, it can cause se!ere disepeople with HIV (human immunodefciency !iru

    able to ta*e ad!anta"e o a wea*ened imsystem, which is why it7s called an opportinection. &he most common illness #V cauretinitis, an eye inection that can lead to blindn

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    HIV(!e'ated en%e&)a'o&at8ten reerred to as HIV5AIDs're

    dementia, it can be defned ade"enerati!e brain condition a4epatients with #D$ counts o less 9::. #urrent estimates su""es

    impacts rou"hly ;< percent o patients.

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    He!&es si"&'e* +%)!oni%, a)e!&es -oste!

    Herpes simple can be characteri3ered, painul sores that appear onmouth or "enital area. Herpes 3osteshin"les, presents with painul bli

    on s*in suraces. =hile there is no or either, medications are a!ailaballe!iate some symptoms.

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    Herpes simple

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    He!&es .oste!

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    Histo&'as"osisInection by a un"us ound in

    droppin"s o birds and bats in hareas. It is not serious i confnethe lun"s but can be atal i spthrou"hout the body.

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    Isos&o!iasis

    &his parasitic un"us de!elops

    patients drin* or come into contactcontaminated ood and water sourcis currently treated with antipardru"s. Isosporiasis is a human inte

    disease caused by the parasite Isosbelli. It is ound worldwide, especiatropical and subtropical areas.

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    a&osi0s sa!%o"a

    &his orm o cancer oten presents

    either oral lesions or lesions co!ethe s*in suraces. #urrent treatminclude radiation and5or chemotheto shrin* the tumors and antiretro

    therapy to boost the body/s #D$count.

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    1ymphoma

    A !ariety o cancers requently pre

    in HIV5AIDS patients. &reatment!ary based upon the cancer typecondition o the patient.

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    ycobacterium a!ium comp

    &hese en!ironmental bacteria opresent in patients with se!compromised immune systems, cell counts o less than

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    Pneu"o%ystis %a!inii&neu"onianeumocystis pneumonia (#- is a se

    inection that causes in>ammation>uid buildup in the lun"s. It is causedun"us called neumocystis +iro!eci. &is currently the leadin" cause o dea

    HIV5AIDS patients. #areul monitorin"antibiotic therapies are currently usetreat the patient ollowin" dia"nosis.

    Pneu"oniathat has become chronic.

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    P!og!essive "u'ti1o%a''eukoen%e&)a'o&at)y

    &his neurolo"ical condition oa4ects patients with #D$ cell cobelow ;::. =hile there is no cu

    treatment or this disease, sresponse has been shown antiretro!iral therapies.

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    To*o&'as"osis&his parasitic inection comm

    stri*es HIV5AIDS patients with #D$counts that ha!e allen below rophylais treatments are used pre!enti!e measure or pat

    postin" low #D$ cell counts.

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    &uberculosis.

    ost common in low'income areas o

    "lobe, tuberculosis can be succestreated in most cases i cau"ht earlis a disease caused by a bactecalled ycobacterium tuberculosis.

    bacteria usually attac* the lun"s, bbacteria can attac* any part o the such as the *idney, spine, and brain

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    =astin" syndrome (HIV'relatDefned as unwanted body loss a

    total wei"ht loss o more thanpercent o the patient/s normal wei"ht. &reatment in!ol!es diemana"ement and conti

    antiretro!iral therapy.

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    &he HIV !irus puts people at ris* or a wide ra

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    &he HIV !irus puts people at ris* or a wide rainections. &his can include a number o conditiocan lead to rashes, sores, and lesions. S*in conare amon" the earliest si"ns o the presence o

    the body. &hey/re oten !iewed as mar*ers disease/s pro"ression. Accordin" to Indian @ouSeually &ransmitted Diseases and AIDS, appro: percent o all people with HIV will ha!e rasymptoms durin" the course o their diseaserelated rashes "enerally all into one o three cate

    9.Cenerali3ed dermatitis

    ;.)acterial, un"al, !iral, and parasitic inections

    .S*in tumors

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    2ene!a'i-ed De!"atitisDermatitis, or "enerali3ed s*in rashe

    the most commonly eperienced symo HIV. Some typical types o dermareB

    9. Eerosis

    Eerosis is dryness o the s*in, which appears as dry, itchy, and scaly s*in paon the arms and le"s.

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    34 Ato&i% De!"atitis&his is a chronic in>amma

    condition. It oten causes red, sand itchy rashes.

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    54 P!u!igo Nodu'a!is

    ruri"o nodularis is a condition in which lum

    the s*in cause scab'li*e appearancesitchiness. &his type o dermatitis is typicallyamon" people with etremely comproimmune systems.

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    64 7osino&)i''i% Fo''i%u'it&his s*in disease is characteri3e

    itchy, red bumps centered on ollicles in the upper body. &his ordermatitis is ound most requentpeople in later sta"es o the disea

    pro"ression.

    In1e%tions

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    A number o bacterial, !iral, un"al, and painections impact people inected with HIV dthe course o their disease. &he most comreported inections includeB

    9. Herpes Foster

    Herpes 3oster is caused by the same unde!irus as household chic*enpo. It can

    shin"les, a condition in which painul s*in rand bumps appear in people with HIV. &reaoten in!ol!es anti!iral dru" re"imens.

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    3 M '' C i

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    34 Mo''us%u" Contagiosuolluscum conta"iosum

    characteri3ed by pin* or >esh'cobumps on the s*in. &his hconta"ious s*in !irus oten imppeople with HIV. Gepetiti!e treatm

    may be needed to completely ridbody o these unwanted bu#urrent treatment options, accoto @ohns Hop*ins, include ree3in"

    bumps with liquid nitro"en to

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    5 O ' H i L k ' ki

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    54 O!a' Hai!y Leuko&'akia

    &his oral !iral inection can

    characteri3ed as thic*, white lesionthe ton"ue. 8n"oin" antiretrotreatments will impro!e the boimmune system and ability to rid

    o this !irus.

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    6 T) )

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    64 T)!us)&his un"al inection causes a

    white layer on the ton"ue. recurrent inection can be challento treat. #urrent options incantiun"al medications, oral ri

    and oral lo3en"es.

    Ski L i

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    Skin Lesions

    9. aposi sarcoma, a orm o cancer

    impacts the linin" o lymph nodes or !essels, appears as dar* lesions on thethat are brown, purple, or reddish in

    &his orm o cancer can impact the ldi"esti!e tract, and li!er. It can cshortness o breath, diculty breathin"swellin" o the s*in.

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