conclusion in conclusion, preliminary data from this nutrition intervention study suggest that a...

Conclusion Conclusion In conclusion, preliminary data from this nutrition intervention study suggest that a well balanced Mediterranean-type diet is able to reduce several metabolic risk factors in Greek patients with CM diseases. Purpose Purpose A prospective, randomized, controlled nutrition intervention study in order to evaluate the impact of a 6-month balanced Mediterranean-type diet on cardiovascular risk factors in Greek adults with known cardiometabolic (CM) diseases. Subjects Subjects - Methods Methods We present here preliminary results for 384 patients from a total of 8000 estimated to finally participate in the study, recruited from 50 randomly selected municipalities in Greece. From these 384, 79.9% had obesity, 19% type 2 DM, 55.1% hyperlipidemia, 50.6% hypertension and 14.6% cardiovascular disease (CVD), e.g. coronary disease or stroke. All subjects were randomized into 2 groups and followed for 6 months. The intervention group (I) received a Mediterranean healthy diet personalized in calories and nutrients according to the patient’s diseases, and was followed monthly by a dietitian, whereas the control group (C) did not receive any dietary counseling. Measurements: BMI, %Body Fat (%BF) by BIA, waist circumference(W), serum lipids (TC,TG,LDL-C,HDL-C), Fasting plasma glucose (FPG), HBA1c (only in diabetic patients), Systolic (SBP) and Diastolic (DBP) blood pressure. Table 1: Anthropometric and metabolic parameters before and after intervention (duration of 6 months) A Mediterranean-type Nutrition A Mediterranean-type Nutrition Intervention Program in Greek Intervention Program in Greek Municipalities for Patients with Municipalities for Patients with Cardiometabolic Diseases Cardiometabolic Diseases MARIA CHASAPIDOU, THEMISTOKLIS TZOTZAS, IOANNIS PAGKALOS, KONSTANTINOS MARIA CHASAPIDOU, THEMISTOKLIS TZOTZAS, IOANNIS PAGKALOS, KONSTANTINOS TZIOMALOS, KONSTANTINA PAPADIMITRIOU TZIOMALOS, KONSTANTINA PAPADIMITRIOU Department of Nutrition and Dietetics, TEI Thessaloniki, Greece Department of Nutrition and Dietetics, TEI Thessaloniki, Greece Percentage of Percentage of mean mean difference difference p p ΒΜΙ ΒΜΙ - 4.0% - 4.0% < 0.001 < 0.001 % % Body Fat Body Fat - 2.8% - 2.8% < 0.05 < 0.05 W (cm) W (cm) - 4.1 % - 4.1 % < 0.001 < 0.001 LDL-C LDL-C (mg/dl) (mg/dl) - 7.9% - 7.9% = 0.05 = 0.05 FPG(mg/dl) FPG(mg/dl) - 7.1% - 7.1% < 0.001 < 0.001 SBP (mmHg) SBP (mmHg) - 5.1% - 5.1% < 0.05 < 0.05 Intervention Group Intervention Group (Ι) (Ι) Before Before After After p p ΒΜΙ ΒΜΙ 33 33 . . 7 ±5 7 ±5 . . 6 6 32 32 . . 5±5 5±5 . . 4 4 < 0.001 < 0.001 % % Body Fat Body Fat 39 39 . . 4±8 4±8 . . 4 4 38 38 . . 2±9 2±9 . . 0 0 0.002 0.002 W W (cm) (cm) 106 106 . . 7±14 7±14 . . 1 1 102 102 . . 5±12 5±12 . . 7 7 P < P < 0.001 0.001 LDL-C (mg/dl) LDL-C (mg/dl) 137 137 . . 0 ± 0 ± 32.5 32.5 121 121 . . 7 ± 7 ± 28.4 28.4 0.004 0.004 FPG(mg/dl) FPG(mg/dl) 107 107 . . 6 6 ± ± 21.3 21.3 100 100 . . 8 ± 8 ± 19.1 19.1 0.001 0.001 SBP (mmHg) SBP (mmHg) 83 83 . . 5 ± 5 ± 9.8 9.8 81 81 . . 1 ± 1 ± 10.1 10.1 0.035 0.035 REFERENCES REFERENCES 1.Ezzati M and Riboli Ε. Behavioral and Dietary Risk Factors for Noncommunicable Diseases. N Engl J Med 2013;369:10. 2.Lim SS, Vos T, Flaxman AD, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2224-60 2014 – SAN FRANCISCO, CA ADAs 74 th Scientific Sessions Results Results A total of 316 patients [181 group (I) and 135 group(C)], aged 58±4, 0 y, 77,5% women, age and sex-matched, finally completed the study. Anthropometric and metabolic parameters before and after intervention in group (I) and percentage of significant mean difference (in parenthesis) between groups (I) and (C) were as follow: Table 2: Percentage of significant mean difference between groups (I) and (C)

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Page 1: Conclusion In conclusion, preliminary data from this nutrition intervention study suggest that a well balanced Mediterranean-type diet is able to reduce

PurposePurposeA prospective, randomized, controlled nutrition intervention study in order to evaluate the impact of a 6-month balanced Mediterranean-type diet on cardiovascular risk factors in Greek adults with known cardiometabolic (CM) diseases.

SubjectsSubjects - MethodsMethodsWe present here preliminary results for 384 patients from a total of 8000 estimated to finally participate in the study, recruited from 50 randomly selected municipalities in Greece. From these 384, 79.9% had obesity, 19% type 2 DM, 55.1% hyperlipidemia, 50.6% hypertension and 14.6% cardiovascular disease (CVD), e.g. coronary disease or stroke. All subjects were randomized into 2 groups and followed for 6 months. The intervention group (I) received a Mediterranean healthy diet personalized in calories and nutrients according to the patient’s diseases, and was followed monthly by a dietitian, whereas the control group (C) did not receive any dietary counseling. Measurements: BMI, %Body Fat (%BF) by BIA, waist circumference(W), serum lipids (TC,TG,LDL-C,HDL-C), Fasting plasma glucose (FPG), HBA1c (only in diabetic patients), Systolic (SBP) and Diastolic (DBP) blood pressure.

Table 1: Anthropometric and metabolic parameters before and after intervention (duration of 6 months)

A Mediterranean-type Nutrition Intervention Program A Mediterranean-type Nutrition Intervention Program in Greek Municipalities for Patients with in Greek Municipalities for Patients with

Cardiometabolic Diseases Cardiometabolic Diseases

MARIA CHASAPIDOU, THEMISTOKLIS TZOTZAS, IOANNIS PAGKALOS, KONSTANTINOS MARIA CHASAPIDOU, THEMISTOKLIS TZOTZAS, IOANNIS PAGKALOS, KONSTANTINOS

TZIOMALOS, KONSTANTINA PAPADIMITRIOUTZIOMALOS, KONSTANTINA PAPADIMITRIOU Department of Nutrition and Dietetics, TEI Thessaloniki, GreeceDepartment of Nutrition and Dietetics, TEI Thessaloniki, Greece

Percentage of Percentage of mean mean differencedifference

ΒΜΙΒΜΙ - 4.0%- 4.0% < 0.001< 0.001%% Body Fat Body Fat - 2.8%- 2.8% < 0.05< 0.05W (cm)W (cm) - 4.1 %- 4.1 % < 0.001< 0.001LDL-C (mg/dl)LDL-C (mg/dl) - 7.9%- 7.9% = 0.05= 0.05FPG(mg/dl)FPG(mg/dl) - 7.1%- 7.1% < 0.001< 0.001SBP (mmHg)SBP (mmHg) - 5.1%- 5.1% < 0.05< 0.05

Intervention GroupIntervention Group (Ι)(Ι)BeforeBefore AfterAfter pp

ΒΜΙΒΜΙ 3333..7 ±57 ±5..66 3232..5±55±5..44 < 0.001< 0.001%% Body Fat Body Fat 3939..4±84±8..44 3838..2±92±9..00 0.0020.002WW (cm)(cm) 106106..7±147±14..11 102102..5±125±12..77 P < P <

0.0010.001LDL-C (mg/dl)LDL-C (mg/dl) 137137..0 ±0 ±

32.532.5121121..7 ±7 ± 28.4 28.4 0.0040.004

FPG(mg/dl)FPG(mg/dl) 107107..6 ±6 ±21.321.3 100100..8 ±8 ±19.119.1 0.0010.001SBP (mmHg)SBP (mmHg) 8383..5 ±5 ±9.89.8 8181..1 ±1 ±10.110.1 0.0350.035

REFERENCESREFERENCES1. Ezzati M and Riboli Ε. Behavioral and Dietary Risk Factors for Noncommunicable Diseases. N Engl J Med 2013;369:10.2. Lim SS, Vos T, Flaxman AD, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in

21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2224-60.

2014 – SAN FRANCISCO, CA ADAs 74th Scientific Sessions

ResultsResults A total of 316 patients [181 group (I) and 135 group(C)], aged 58±4, 0 y, 77,5% women, age and sex-matched, finally completed the study. Anthropometric and metabolic parameters before and after intervention in group (I) and percentage of significant mean difference (in parenthesis) between groups (I) and (C) were as follow:

Table 2: Percentage of significant mean difference between groups (I) and (C)