conference synthesis: summary & recommenda6ons ... - pmac€¦ · rao mdr:ds 5.7 6.3 23.1 4.7...
TRANSCRIPT
![Page 1: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/1.jpg)
ConferenceSynthesis:Summary&Recommenda6ons
Saturday3February2018
Saturday, February 3, 18
![Page 2: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/2.jpg)
2
• Pre-conference:29–31January2018• 40sidemee;ngs• 6fieldtrips
• Mainconference1–3February2018• 4Keynoteaddresses• 4plenarysessions• 20parallelsessions• 5Booklaunches• 60E-posterpresenta;ons• WorldArtContest:468entriesfrom14countriespar;cipated
• Totalregisteredpar;cipants• 1,263par;cipantsfrom85countries(F48%,M52%)
Conferenceprogrammestructure
Saturday, February 3, 18
![Page 3: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/3.jpg)
3
24Plenaryandparallelsessions142Moderators/speakers/panelists
Gender
Exper6se
WHORegions
Saturday, February 3, 18
![Page 4: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/4.jpg)
Problemstreams
4Source:SlidefromPS2.4,KohlK.
Saturday, February 3, 18
![Page 5: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/5.jpg)
ExamplesYellowFever,Angola2016• 2016(January–July):3,552YellowFevercasesfromallprovincesofAngola,355deaths
• Interna;onalspread:fromAngolatotheDRC(59confirmedcases),Kenya(2confirmedcases)andChina(11confirmedcases)
MDRTB• MDR-TBisapublichealthcrisisandahumansecuritythreat.WHOes;mates600,000newcasesgloballywithresistancetorifampicin–themosteffec;vefirst-linedrug-ofwhich490,000areMDR-TB.
• Costoftreatment(USDperpa;ent)
5
HIC UMIC LMIC LICDrugSensi;veTB 14,659 840 273 258MDRTB 83,365 5,284 6,313 1,218Ra;oMDR:DS 5.7 6.3 23.1 4.7
Source:PharmacoEconomics(2015)33:939–955hcps://goo.gl/H8QxxQ
Saturday, February 3, 18
![Page 6: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/6.jpg)
ExamplesArtemisininresistantMalaria• SoutheastAsiaistheepi-centreofan;-malarialdrugresistanceandoneofthemostpopulartraveldes;na;ons,with104millioninterna;onaltravellersin2015,facilita;nginterna;onalspread
• 38and90%oftheartemisininmedicinesonthemarketweresubstandardorfalsified
FigureMapofprevalenceofK13muta;onsfromK13MolecularSurvey,accessed16November2016.
6Source:LancetInfectDis2017;17:491–97hcps://goo.gl/3uYa9w
Saturday, February 3, 18
![Page 7: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/7.jpg)
ExamplesARTdrugresistance• Prevalenceofvirologicfailurewas10.4%ageroneyearofan;viraltreatmentinChina[BioMedResearchInterna;onal,2016]
• OverallprevalenceofprimaryHIVdrugresistancewas7.9%inThailand[PLOSOne].
AMRchallenges
• InOECDin2014,15%ofoveralladmissionshadanAMRinfec;on,andforthetopthreecountriesthiswas25%,11;meshigherthanthelowestthreecountries[OECD2016];
• mostcommonpathogens• 3rdgenera;oncephalosporin-resistantE.Coli• Carbapenem-resistantK.pneumoniae
7
Saturday, February 3, 18
![Page 8: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/8.jpg)
Objec;vesofPMAC2018ACTIONFOCUSEDaddressingEIDandAMR1. Problemstream
• UnderstandthedriversofEIDandAMR2. Solu;onstream
• Accelerateprogressonmul;-sectoralac;ons• Advocateevidence-basedpriorityselngandpolicies• PMACaslearningandsharingplamorm
3. Evidenceforpolicydecisions• Underscorethesecurity,socio-economicanddevelopmentbenefitsfromOneHealthac;on
Structureofthesynthesis• Drivers,consequences,costofinac;onforEIDandAMR• Solu;ons• Crossculngrecommenda;ons
8
Saturday, February 3, 18
![Page 9: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/9.jpg)
I.EmergingInfec;ousDiseases
Maindrivers
9Source:SlidefromPL0,FinebergH. Source:TerrolioZ.etal.2015.fromPS4.5
Saturday, February 3, 18
![Page 10: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/10.jpg)
Maindriverscon;nued• Increasedcontactsbetweenhumansandanimals• Moreoutbreaksofemergingorre-emerginginfec;ousdiseasesaffectmorepeople.Urbaniza;onhasledtomoreurbanoutbreaks(e.g.yellowfeverinAngola)whichposesignificantchallengesintermsofscaleofresponseandpoten;alinterna;onalamplifica;on
• Poorandmarginalizedpopula;onspar;cularlyaffected,e.g.peopleonthemove—internal,interna;onaldisplacedpersons,pastoralists
• UNICEF’sresponsetopoten;alCholeraoutbreakhcps://youtu.be/FvCexK18hiU
10
Saturday, February 3, 18
![Page 11: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/11.jpg)
Saturday, February 3, 18
![Page 12: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/12.jpg)
Costofinadequatesurveillanceandresponse
• Thecostofpreparednessisatleast10;mesless• “Preparednesscostsmillions,responsecostshundredsofmillionsandrecoverycostsbillions”.
• Theimpactisnotonlyfinancialoreconomicitisalsosocialandpoli;cal
Examples• MERS-CoVoutbreakintheRepublicofKorea,2015
• atotalof186personshavebeeninfected,38ofwhomhavedied
• Foreigntouristsdecreasedby41%comparedwithMay2014.TotaleconomiclossofUS$10billion;0.1%reduc;oninGDPgrowthin2015.[EuroSurveill.2015;20(25)]
12
Saturday, February 3, 18
![Page 13: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/13.jpg)
Ebolaaffectedcountries:Guinea,LiberiaandSierraLeone(2014-16)
Source:SlidefromYamamotoN.(PS1.4)
13
• 11thousanddeathsfromEbolaepidemic,althoughEbolawasdiagnosedin1976
• Inadequatecapacitytorespond
• Fragilehealthsystems• Lackofinvestmentinhealthandhealthsystems
• Poorhealthdeliveryinfrastructure
• Novaccinehadbeendeveloped
Saturday, February 3, 18
![Page 14: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/14.jpg)
Thailand’sresponsestoMERS-CoV• AnOmanipa;ent(2015)
• Day1:withheartcondi;onwasdiagnosedwithpneumoniaonhospitaladmission
• Day2and3:twofalsenega;vetestsonupperrespiratorytractsamples• Day3:subsequentsputumexamconfirmedMERS-CoV• Pa;entwasmovedbackintothenega;vepressureunitandtransferredtoInfec;ousDiseaseIns;tute,MOPH
• Over170contactsweretraced;48werequaran;nedand122self-monitoredsymptoms.High-riskclosecontactsexhibi;ngnosymptoms,andthosewhoselabteston12thdayagerexposurewasnega;ve,werereleasedonthe14thday
• TheOmaniMinistryofHealth(MOH)wasno;fiedusingIHR2005mechanisms.Outbreakinves;ga;onwasconductedinOmanandfindingswerepublishedonWHOintranetandsharedwithThailand’sIHRfocalpoint
• Keytosuccessfulinfec;oncontrol,withnosecondarytransmission,wascollabora;veeffortsamonghospitals,laboratoriesandMOHsofbothcountries
14
Saturday, February 3, 18
![Page 15: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/15.jpg)
Solu;onstoEID• ImproveandsustaintheIHRcorecapaci6es• Strengtheninterven;onsatthehumananimalinterface• Peoplecenteredresponsesincludingcommunityandcivilsocietyengagement,leavingnoonebehind,focusonthemostvulnerablepopula;ons
• Renewedgovernance• Transparencyandaccountabilityofna;onalgovernmentforpreparednessandresponse
• Trustandcollec;vecommitment• Coordina;on:mul;-partner,mul;-disciplinaryandmul;culturalresponseteams
• Op6mizepartnerships:incen;vizecollabora;on;jointobjec;vesbasedonlocalneeds
• Buildcapaci6esdealingwithexis;ngthreatsandepidemicstoensureadequatesystems
• Approaches• Investinsystemsnotprojects• 2facesofthesamecoin:healthsecurityandprimarycare• Engagepoli;ciansandfinancialstakeholders,increasetheirawarenessbefore
15
Saturday, February 3, 18
![Page 16: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/16.jpg)
Lessonsofexperienceandgoodprac;ces• Engagethemediaproac;velyandatanearlystageoftheresponse,shapethenarra;ve,remainflexibleinmessagedevelopment(e.g.BrazilYellowfever)
• Preparethehealthsystemtorespond,trainhealthworkerstocopewithunexpectedoutbreaks,improveinfec;onpreven;onandcontrol
• Improvegeneralpublicliteracyabouttherisksandpreven;onmeasures• Learnfromothercountries’experience• Integratesurveillancedatasources(human,animal,communitysurveillance)• Usebigdataforsurveillancebutfocusonqualityanalysis(“reducenoise”)• Produceeconomicmetricsonhealthsystemspreparednesstoraiseandsustainawarenessofpoli;ciansanddecisionmakers
• Includeprivatesectorinpreparednessandresponse• Includepastoralistsandnomadicpopula;onsinsurveillance,biosecurityandpolicydialoguetofindinnova;veandcostefficientsolu;ons
16
Saturday, February 3, 18
![Page 17: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/17.jpg)
II.AMR
17
Saturday, February 3, 18
![Page 18: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/18.jpg)
ThekeydriversofAMR
• An;microbialmisuseandoveruse• Environmentalcontamina;on• Health-caretransmission• Subop;malrapiddiagnos;cs• Subop;malvaccina;on• Subop;maldosing• Interna;onaltravelfacilita;ngspreadofAMRpathogens• Substandardandfalsifiedan;microbials
18
Saturday, February 3, 18
![Page 19: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/19.jpg)
Consump6onofan6microbialsinfoodanimals
19
Source:SlidefromPL0;FinebergH.
Globalconsump;onofan;microbialsinfoodanimalproduc;on
• 2010:Es;matedat63,151(±1,560)tonnes• 2030:Projectedtoriseby67%,to105,596(±3,605)tonnes• Increasedconsump;onisdrivenbythegrowthinconsumerdemandforlivestockproductsinmiddle-incomecountries,andshigtolarge-scalefarmswherean;microbialsareusedrou;nely.
• HotspotssuchasIndiawhereareasofhighconsump;on(30kgperkm2)forindustrialpoultryproduc;onareexpectedtogrowby312%by2030
Saturday, February 3, 18
![Page 20: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/20.jpg)
20
Source:Van Boeckel et al., 2015, PNAS (slide from PS4.5, LaxminarayanR.)
An6bio6cconsump6oninlivestock,toptencountries2010–2030(projectedfor2030)
Source:SlidefromPS4.5,LaxminarayanR.
Saturday, February 3, 18
![Page 21: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/21.jpg)
Useofan;microbialagentsforGrowthPromo;on
In2015,atotalof96outof130(74%)OIEMemberCountriesdidnotauthorizean;microbialagentsforgrowthpromo;oninanimals;increasedfrom77outof151(51%)in2012
21
Authorisa6onofAn6microbialGrowthPromotersin130OIEMemberCountries,2015
Source:OIEAnnualReportontheuseofan;microbialagentsinanimals.2016
Saturday, February 3, 18
![Page 22: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/22.jpg)
Substandardandfalsifiedan;bio;cs:notadequatelyaddressedbyGAP-AMR
Costofinac6on• Ofthe48,000samplesofmedicinestestedforquality(66%An;microbials)
• 10.6%failurerate,equivalenttoannualspendof$30.5billiononSFproducts
Impactsofsubstandardandfalsifiedan6bio6csandan6microbials• Es;mated72,430-169,271deathsofchildhoodpneumoniaduetoSFan;bio;cs
• Addi;onal116,000deathsfrommalariainSubSaharanAfricaduetoSFan;-malarialdrugs,and$38.5m.addi;onaltreatmentcostduetofailureofini;altreatment.
Rootcauses• Poorgovernance:corrup;on,unethicalprac;ces,poorprocurement• WeakNa;onalRegulatoryAuthoritycapacity
22
Saturday, February 3, 18
![Page 23: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/23.jpg)
23
Source:SlidefromPS1.3,BondK.
Saturday, February 3, 18
![Page 24: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/24.jpg)
Solu;onsforAMR
1. Ac;veimplementa;onofna;onalac;onplanonAMR,strengthenins;tu;onalcapaci;esontwomajorfronts
2. Monitoringstrand:surveillanceforpolicy:• An;microbialconsump;oninhumanandanimalsectors• AMRinhumanandanimals• Integratedsurveillanceinfoodchain• ABresiduesandAMRinenvironment• Pointprevalencesurveystocaptureprevalenceofhealthcareassociatedinfec;onsandAMR,AMUinhealthfacili;es,AMRacributedmortalityandeconomiclossas%GDP
• Post-marke;ngqualityofmedicines,recallofSFproductsandlegalac;on
• Disposalofexpiredan;bio;cs
24
Saturday, February 3, 18
![Page 25: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/25.jpg)
Ac;onStrand1.Redesignlivestockproduc;onsystemse.g.breedsandvaccines;husbandry–stockingdensi;es;qualityofwaterandfeed
2.Improvean;bio;cstewardship• Developandenforceclinicalprac;ceguidelines,dispensingandprescrip;onaudits,peer
support,counsellingandcon;nuedprofessionaleduca;on• Improvean;bio;cliteracyandAMRawareness• Strengthenan;bio;cliteracyinprofessionals• Regula;on:reclassifica;onofan;bio;csintothreegroups:access,watchandreserve;and
limiteduseofreservegroup• Regulatebycappingan;microbialsper‘popula;oncorrec;onunit’
3.Strengtheninfec;onpreven;onandcontrolinhealthcarefacili;es
4.ResearchandDevelopment• HealthpolicyandsystemsresearchonAMR• PublicinvestmentinR&Dinnovelmoleculesanddiagnos;cs• Researchforalterna;ves,e.g.autogenousvaccines
Needtoaddresshugeimplementa6oncapaci6esgap
25
Saturday, February 3, 18
![Page 26: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/26.jpg)
III.CrossCulngRecommenda;ons
26
Saturday, February 3, 18
![Page 27: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/27.jpg)
1. RaiseEIDandAMRtothena;onalhumansecurityagenda2. Goodgovernance,accountabilityandtransparencyto
addresscorrup;on• Mul;sectoralac;onforhealth• Public-private-community-civilsocietyengagement
27
Saturday, February 3, 18
![Page 28: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/28.jpg)
3.RoleofLeadership
28
Saturday, February 3, 18
![Page 29: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/29.jpg)
4.Trustamongpartners• trustbuildingbeforediseaseoutbreak• sharedvision,sharedunderstanding• commonvalues• ac;ngwisely
29
Saturday, February 3, 18
![Page 30: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/30.jpg)
5.OneHealthSystemStrengthening:human,animalandenvironment
30
Source:SlidefromPS4.4,PolicarpioS.L.
Saturday, February 3, 18
![Page 31: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/31.jpg)
6.Riskcommunica;onsduringepidemics/pandemics
31
Saturday, February 3, 18
![Page 32: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/32.jpg)
7.R&Dandevidencebasedpolicy
32
Saturday, February 3, 18
![Page 33: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/33.jpg)
8.Healthsecurityfinancing:size,sources,flowoffund• Donorsneedtoinvestmoreinna;onalpreparedness• Innova;veapproachestomaximizeefficiencyofspending–digital,newtechnology,buildingonhumangenomeproject
• Poli;calcommitmenttosecuredomes;cresources• Integra;onofhealthsecurityfinancingprocessintocountrybudge;ngprocess
33Source:SlidefromPS4.5,YameyG.
Saturday, February 3, 18
![Page 34: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/34.jpg)
Summary
• Economicinvestmentforpreven6ngEIDandAMR• Strengtheneconomicevidencebase,e.g.costofinac;on(“hiddenlosses”),calculateReturnonInvestment
• Scaleeconomicallyinformedinnova6ons,e.g.land-useplanningthataccountsforeconomicimpactofdiseaseemergencefromdisruptedlandscape
• Incen6vizeriskmi6ga6on,e.g.incorporateepidemicriskprofilesintomacro-economicanalysesandbondra;ngs
• Mobilizefunds:domes;candODA• KeeppandemicsandAMRattopoftheagenda:G7,G20,GlobalHealthSecurityAgenda
34
Saturday, February 3, 18
![Page 35: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/35.jpg)
Specialthanks
Mr.SamBradd,fromDrawingChangeforthewonderfulgraphicrecording.
35
Saturday, February 3, 18
![Page 36: Conference Synthesis: Summary & Recommenda6ons ... - PMAC€¦ · Rao MDR:DS 5.7 6.3 23.1 4.7 Source: PharmacoEconomics (2015) 33:939–955 hcps://goo.gl/H8QxxQ Saturday, February](https://reader034.vdocument.in/reader034/viewer/2022042217/5ec02e06d0a8900abe22e09c/html5/thumbnails/36.jpg)
Rapporteurcoordinator:WalaipornPatcharanarumol,WarisaPanichkriangkrai,AngkanaSommanustaweechai
LeadRapporteur1.Prof.DameAnneMills2.Dr.SylvieBriand3.Dr.JulieRSinclair 4.Dr.JuanLubroth5.Dr.VirojTangcharoensathien1 Aimee Lee 23 Kanokwaroon Watananirun 45 Noppawan Piaseu 67 Suladda Ponguca
2 Anond Kulthanmanusorn 24 Kanthika Imsaengjan 46 Orana Chandrasiri 68 Sunicha Chanva;k
3 Arisa Hisamatsu3rd 25 Karnsinee Yotsakulsate 47 Orarat Wangpradit 69 Supanan Inphlang
4 Benjaporn Niyomnaitham 26 Kasama Thongbaeb 48 Palita Rodanant 70 Suphanna Krongthaeo
5 Bowwarn Juengwacanasirikul 27 Keiko Tsukamoto 49 Pan;la Taweewigyakarn 71 Surangrat Jiranantanagorn
6 Cameron Tabrizi 28 Konvika Chantarat 50 Pa;nya Srisai 72 Suriwan Thaiprayoon
7 Carol DayoObure 29 Kritchavat Ploddi 51 Payao Phonsuk 73 Taketo Tanaka
8 Chainarong Sukputanan 30 Li Niu 52 Piyawan Kanan 74 Tanapat Laowahutanon
9 Charay Vicahthai 31 Maho URABE 53 Pranpriya Chaypho 75 Thanachol Wonghirundecha
10 Chayanis Kositamongkol 32 Maki Sakuma 54 Raththar Benchapalanont 76 Theerut Densathaporn
11 Chayut Pinichka 33 Manushi Sharma 55 Rei Haruyama 77 Thuyen Nguyen
12 Chu;ma Akaleephan 34 Mariam Parwaiz 56 Rick Brown 78 Ti;porn Tuangratananon
13 EiEi Aung 35 Myelone Tharmasselan 57 Sakditat Ilphisit 79 Uravadee Chanchamsang
14 Hathairat Kosiyaporn 36 Nareerut Pudpong 58 Saowaluk Srikajornlarp 80 Vasinee Singsa
15 Huijuan Liang 37 Nicolas Rosemberg 59 Sarayuth Khuntha 81 Voleak Van
16 Inthira Yamabhai 38 Nisachol Cechakrikul 60 Saudamini Dabak 82 WeiPin Hung
17 Jaruayporn Srisasalux 39 Nissara Spence 61 Shaheda Viriyathorn 83 Wilailak Saengsri
18 Jeannece Wong 40 Nitchakorn Tangsathapornpanich 62 Sirinard Nipaphorn 84 Woranan Wichayapipopsakul
19 Jing WANG 41 Nongnapas Assawamasbunlue 63 Smith Kuprasertvong 85 Xian Sun
20 Jintana Jankhotkaew 42 Nongnuch Jaichuen 64 Sophavanh Thitsy 86 Yasmeen Vaheng
21 Joseph Harris 43 Nongyao Kasatpibal 65 Suchunya Aungkulanon 87 Yumiko Miyashita
22 Jurairat Phromjai 44 Noppakun Thammatacharee 66 Sukanya Numsawat
Saturday, February 3, 18