Conference & User Meeting

Unique in Life Science research

Company Overview

Product Strategy

Industry Analysis

Business Model Business Model

Management Team

Research & Discovery for Life Science

• ChemBioOffice

• ChemBioDraw

• Chemical & BiologicalResearch Informatics

• Laboratory, Development &Manufacturing Informatics

• Knowledge Management• Knowledge Management

• Chem & Bio E-Notebook

• Process Chemistry &Compliance Execution

ChemOfficeBioOffice

Desktop Software to Enterprise Solutions

DESKTOP

ChemDraw

E-Notebook

SOFTWARE

ENTERPRISE SOLUTIONS

Bio Informatics

Chem Informatics

Cloud

1985 1990 2000 20051995

TECHNOLOGY TRANSISTIONS

DesktopSoftware

2010

Enterprise Solutions

CloudComputing

Desktop Research Standard for ScientistsChem & Bio Office

The Researcher’s complete Desktop suite

Communication Standard for ScientistsChem & Bio Draw

Structures for Chemists

Pathways for Biologists

Comprehensive Integrated Knowledge ManagementE-Notebook

Configured to Individual Function Workflow

Databases provide Knowledge to ScientistsChemBioFinder Gateway

OF CHEMISTRY

100,000CHEMICAL LINKS

36,000,000ANNUAL PAGE VIEWS

Early Adoption by Broad Customer base PHARMACEUTICALS

• Merck • GlaxoSmithKline

O / S h i

E-Notebook Adoption

BIOTECHS• Amgen• Array BioPharma

A• Organon/ Schering-Plough

• AstraZeneca• Novartis• Abbott Laboratories• Bristol-Myers Squibb• Shionogi• Wyeth

• Arena• Pierre Fabre

CHEMICALS• Lubrizol• Eastman• Rohm & Haas• InfineumWyeth

• Roche• Takeda• Nat Institute of Health• Sanofi Aventis• Eisai

• Dow

FOOD & FRAGRANCE• Philip Morris• Firmenich• Intl Flavors & Fragrance

Integrated Desktop to Enterprise Informatics & Knowledge

Desktop

Enterprise

Consulting Development, Deployment & TrainingGlobal Services

SaaS 24X7 Cloud Computing

US Pacific (-8)US Mountain (-7)

US East (-5)US Central (-6)

AMERICA

-5 GMT

GMTJapan (+9)China (+8)

Europe (+1)E. Europe (+2)

+9 GMT

USA

UKJapan

PACIFICEUROPE

CORPORATE

UK (+0)Singapore (+7)India (+5:30)

EUROPE

SUPPORT

Customers

PHARMACEUTICAL

BIOTECHNOLOGY

CHEMICALS

Business Partners INFORMATION PUBLISHERS

CHEMICAL SUPPLIERS

TEXTBOOK PUBLISHERS

Strategic Vision

COMPREHENSIVE SOLUTION- Decision Support Platform- Content & Applications- Data Visualization

SINGLE TRUSTED VENDER- Worldwide Presence - Technical Expertise & Support- Global Sales & Professional Service

GLOBAL CUSTOMER BASE- Chemistry & Biology Domain Expertise - Global Collaboration Experience- Worldwide Deployment Expertise

Business Strategy

Requirement for Search, Visualization, Reporting & Decision

Global Search

Data Visualization

Reference Content

Application Content

Experiment Management Registration Management

Biology Management Materials Management

Query and Reporting

Decision Support

Scientific Decision Applications

E-NotebookExperiment Synthesis, IP-Protection,E-Signature, Collaboration

ChemBioViz GatewayData Visualization/Predictive Modeling/Decision Support

D MChemical Document Management

BioAssay Screening, Data captureAssay analysis. Graphs

Inventory Materials Life Cycle Management and Tracking

RegistrationRegistration, Duplication Check, Mixture Support, Structure captureIndexing, Search & Find

Core Platform

Architecture

Scientific Intelligence

CartridgeChemBioDraw

Workflow LIMS Experimental Workflow Automation

DocManager Search & Find

ChemACXMSDS, EH&SMerck Index

Procurement, PropertiesReactions. Reference Content

Integrated Application WorkflowDatabases

ChemACXMerck IndexMSDS, EH&SGateway

ChemBioVizData VisalizationPredictive ToolsStructural AnalysisDecision Support

E–Notebook

Reaction DatabaseUsers Workspace

Substance Inventory

Biological Experiment

Literature/Commercial

SearchVisualization

Decision SupportPredictive/Structural Analysis

Assay Analysis

Chemical Synthesis

Compound Registration

InventoryMaterials Management

E–Notebook

Users Workspacefor Biology

BioAssay/ BioSAR

Biology Analysisand ReportingIn Vitro & In Vivo

Registration

Compound Database

Enterprise Application Integration

Corporate PortalsCambridgeSoft and Third Party Visualization Technologies

ChemBioViz Gateway

LIMS, SAS

Data Repositories

SAP

ERP

Data Visualization/Predictive Modeling/Decision Support

Workflow LIMS

E-Notebook

Inventory

BioAssay

Registration

DocManager

Core Platform

Architecture

Scientific Intelligence

pChemACXMSDS, EH&SMerck Index

KNIME Partnership

Benefits:

Give access to KNIME workflows to larger number of Scientists,

KNIME users benefit from the global support coverage of CambridgeSoft,

Further integration options with CambridgeSoft products:ChemDraw E-NotebookChemDraw, E-Notebook

Close collaboration to continue to improve open source KNIME: Execution order, Data pipelining

Unique in Pharmaceutical Research & Development IT

Research &Development

Manufacturing& Finance

Marketing & Sales

ERP Siebel CRMChemBioOffice Enterprise

Award Recognition

WWW250 MILLIONPAGE VIEWS

Communication to ScientistsChem & Bio News

PRINT250,000COPIES

EMAIL50 MILLION

EMAILS

PAGE VIEWS

DVD50,000COPIES

COPIES EMAILS

ENGLISH GERMAN FRENCH JAPANESE

Offices & Locations AMERICA

- Cambridge, Massachusetts, USA7 S l L ti- 7 Sales Locations

- 5 Service Locations

EUROPE- Cambridge, United Kingdom- 5 Sales Locations- 5 Service Locations

PACIFIC- Tokyo, Japan- 3 Sales Locations - 3 Service Locations

Employee & Outsource Workers

90 Advanced Degrees, 35 Ph.D.s90 d a ced eg ees, 35 s

Employees

40

45

55

Professional Service

Research & Development

Marketing & Sales

Outsource

100

115

40

10

150

g

General & Administration

Total

25

280

Global Outsource Workforce

USA (2) NetherlandsB l D li Chi

Germany

Over 20 Outsource Cost competitive Sites

Belarus

New Delhi, IndiaMumbai, India

Kochi, India Bangalore, India

Osaka, Japan

Tokyo, Japan

Costa Rica

Dalian, China

LebanonMalta

Hyderabad, India

Donghai, China

Argentina Uruguay

Unique in Life Science research

Company Overview

Product Strategy

Industry Analysis

Business Model Business Model

Management Team

MICHAEL G. TOMASIC– PRESIDENT & CHIEF EXECUTIVE OFFICER– Former MassComp President, Digital Equipment Experience– MBA, Harvard; BS EE, University of Illinois

Management Team

MICHAEL C. RUBENSTEIN– VICE PRESIDENT, DEVELOPMENT & CHIEF TECHNOLOGY OFFICER– Co-Founder of CambridgeSoft– AB Oberlin College

James T. Reilly– VICE PRESIDENT, FINANCE & CHIEF FINANCIAL OFFICER– Former Pegasystems and Digital Equipment Experience

MBA D t th BS IE P d U i it– MBA, Dartmouth; BS IE, Purdue University

MICHAEL R. STAPLETON, Ph.D.– VICE PRESIDENT, CORPORATE DEVELOPMENT– Former Invitrogen and Accelyrs Experience– PhD, MPhil, Chemical Physics, BSc Southampton, Univ, UK

RUSTY W. IRVING– VICE PRESIDENT, GLOBAL SALES– Former Accelrys, Varian and General Electric Experience– MS Chemistry, Tufts University; BA Math, Boston College

Management Team

y, y; , g

FRANCIS J. BATES– VICE PRESIDENT, GLOBAL SERVICES– Former Keane and Digital Equipment Experience– MBA, University of Chicago; BA Chemistry, Holy Cross

JOHN P. McALISTER, Ph.D.– VICE PRESIDENT, CORPORATE STRATEGY– Former Tripos and Evans & Sutherland Experience– PhD Biochemistry Univ of Wisconsin; BS Tarleton State Univ– PhD Biochemistry Univ of Wisconsin; BS Tarleton State Univ

EDWIN P. TIFFANY– VICE PRESIDENT, ADMINISTRATION & TREASURER– Former Emergency Equipment and Turner Fisheries Experience– MBA, Northeastern; BA, University of New Hampshire