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Conferencia “Predicción de características complejas a partir de ADN y genealogías” Dr. Daniel Gianola Master of Science y Ph.D. Animal Breeding, minor in Statistics de University of Wisconsin- Madison Facultad de Ingeniería Universidad ORT Uruguay 14 de diciembre de 2011

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Page 1: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3

Conferencia “Predicción de características complejas a partir de ADN y genealogías”

Dr. Daniel Gianola Master of Science y Ph.D. Animal Breeding, minor in Statistics de University of Wisconsin- Madison

Facultad de Ingeniería

Universidad ORT Uruguay 14 de diciembre de 2011

Page 2: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 3: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 4: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 5: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 6: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 7: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 8: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 9: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 10: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 11: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 12: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 13: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 14: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 15: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 16: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 17: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 18: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 19: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 20: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 21: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 22: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 23: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 24: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 25: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 26: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 27: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 28: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 29: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 30: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 31: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
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Page 33: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 34: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 35: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 36: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 37: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 38: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 39: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 40: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 41: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 42: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 43: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 44: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 45: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 46: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 47: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 48: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 49: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 50: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 51: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 52: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 53: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 54: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 55: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 56: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 57: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 58: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3
Page 59: Conferencia “Predicción de características … PTK ZAP70 Extracellular Plasma membrane Cytoplasm IKB IRS TRAF MYD88-- MAPK7 AP2K4 B MAP2K1 DUSPY 11+ TRAF3 TRPC4 HSPAIA 4 RIPK3

Nck Recruitment to the TCR Required for ZAP70 Activation during … · The Journal of Immunology Nck Recruitment to the TCR Required for ZAP70 Activation during Thymic Development

Molecular testing in NSCLC....PM->EN EGFR HIST3H3 KRT8 PLD2 KRT18 MAP2K1 MAPKU p NIJ MAP3K3 DNM PRKCI PRKCG PRKCBI MAP2K7 MAPKI SMAD3 APPL2 RALBPI REPS? AP2A1 …

Research Article Increased ZAP70 Is Involved in Dry Skin Pruritus …downloads.hindawi.com/journals/bmri/2016/6029538.pdf · 2019. 7. 30. · involvedin dry skin pruritus[,]. is paper

CG Follow IT US VERSION 0826 - contextualgenomics.com · position therapeutic options akt1 alk ar braf ctnnb1 ddr2 egfr erbb2 esr1 gna11 gnaq gnas hras idh1 idh2 kit kras map2k1(mek1)

Expected to say NO · Deletion 13q14, IGVH 3-53 Unmutated CD38 18% (PB; 35% BM), ZAP70 30% May 2006 82.000 WBC, lymphadenopathy slightly increased, palpable tip of spleen Weakness

Comparison of Chronic Lymphocytic Leukemia patients expressing high or low level of ZAP70 mRNA: new prognostic factors, differences in microRNA expression

Regulated unbinding of ZAP70 at the T cell receptor by ... · 2/12/2020  · and Syk kinases and in both families, SH2 domains are implicated in localisation and allosteric activation

Personaldlized Medicine in Cancer · lamp1 lck lifr lphn3 lpp lrp1b ltf ltk maf mafb magea1 magi1 malt1 maml2 map2k1 map2k2 map2k4 map3k7 mapk1 mapk8 mark1 mark4 mbd1 mcl1 mdm2 mdm4

MAP2K1 - GenPath Diagnosticsgenpathdiagnostics.com/wp-content/uploads/2012/01/OnkoMatch.pdfin Solid Tumors AKT1 BRAF KIT MAP2K1 TP53 NRAS. Growth ... Biological discoveries utilizing

TruSight Tumor 170 - Illumina · alk ccnd1 ddr2 fgf1 flt1 kmt2a(mll) mutyh pik3ca ret xrcc2 apc ccnd2 dnmt3a fgf2 flt3 kras myc pik3cb rictor ar ccne1 egfr fgf3 foxl2 map2k1 mycl1

CHAPTER 1 1. INTRODUCTION 1.1 ZAP70 Kinase - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/2437/9/09... · 2015. 12. 4. · 1 CHAPTER 1 1. INTRODUCTION 1.1 ZAP70 Kinase ZAP70,

(which was not certified by peer review) is the author ...Jun 30, 2020  · 266 Calmodulin (CaM) has been shown to bind and regulate the TRPC4 channel (Zhu, 2005; Tang 267 et al.,

Deletion of TRPC4 and TRPC6 in Mice Impairs Smooth Muscle ... · Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo Volodymyr V

Englerin A as a novel potent activator of TRPC4 and TRPC5 ... · PDF filediet Sukumar et al 2012 ... The Max Plank Institute, Dortmund, Germany Herbert Waldmann ... (–)-Englerin

SUPPLEMENTARY INFORMATION - Program for Evolutionary ... · FBXW7 1.53E-02 10 10 0 Late MAP2K1 2.39E-02 8 9 0 Late NRAS 2.39E-02 8 9 0 Late KRAS 3.49E-02 14 11 1 Late BAZ2A 3.58E-02

RASopathies...The RASopathies Noonan 1:1000 to 2500 BRAF CBL KRAS LZTR1 MAP2K1 (MEK1) NRAS PTPN11 RAF1 RASA2 RIT1 SOS1 SOS2 NSML/ LEOPARD BRAF PTPN11 RAF1 Legius SPRED1 NF1 1:3000

CXCR4 signaling and function require the expression of the ... · interacts with the TCR and employs Zap70, the T-cell homolog of Syk, to transduce signals (21–23). A D E B C FG

Research Article Increased ZAP70 Is Involved in Dry Skin

JCI Suppl Figs 171121 RM · 2018. 2. 22. · Supplemental Figure 4. Requirement of Zap70 in γδT cell development (A and B) Flow cytometry analysis of CD5 expression in thymic Vγ6+

QuickScout TM - CarnaBio · lck hck frk ctk csk tec ... ltk ros insr igf1r i r fer fes ret fg r2 fgfr3 fg r4 fgfr1 flt1 kdr flt4 kit fms ... zap70 syk fak pyk2 blk fgr src yes trkb

OPEN Structure of the mouse TRPC4 ion channelsbms.ncu.edu.cn/docs/2019-06/f3c609e662774b96b116f22fe4bac650.pdf · M ammalian transient receptor potential (TRP) channels are activated