In-Depth ReSeARCh eXpeRtISe At youR SeRVICe

Fraunhofer Institution

for Marine Biotechnology (EMB)

Local Manager: Prof. Dr. Charli Kruse

Paul-Ehrlich-Straße 1–3

D- 23562 Lübeck

Phone: +49 (0)451 3844 48-11

Fax: +49 (0)451 3844 48-12

Group Cell Differentiation

Dr. Sandra Danner

Phone: +49 (0)451 3844 48-14

Email: sandra.danner@emb.fraunhofer.de

Group Cell Technology

Dr. Daniel H. Rapoport

Phone: +49 (0)451 3844 48-13

Email: daniel.rapoport@emb.fraunhofer.de

Group Aquatic Cell Technology

Dr. Marina Gebert

Phone: +49 (0)451 3844 48-15

Email: marina.gebert@emb.fraunhofer.de

ContACt

F R A U N H O F E R R E s E A R C H I N s T I T U T I O N

F O R M A R I N E B I O T E C H N O L O G Y ( E M B )

The Fraunhofer Institution for Marine Biotechnology

(EMB) provides products and services in various areas of

applied life sciences research. Starting from developing

new technologies, processes and instruments in the fields

of cell isolation and utilization, cellular test systems as well

as online analysis of living cells are established plus cell-

based medical and laboratory techniques are set up. EMB

scientists work also on biological water quality monitoring,

aquaculture technology, cellular technologies, homoiother-

mic and poikilothermic animal cell cultures.

Thus, the most compelling feature of the EMB is the bund-

ling of competencies from various research fields – plus the

support from an in-house tool shop. A central services lab

supports the creative, solution-orientated and enthusiastic

junior and senior researchers.

Fraunhofer EMB scientists have together with Fraunhofer

Institute for Biomedical Engineering established a cell bank

for wild and rare animals – the German Cell Bank for wildlife

‚Alfred Brehm‘ (CRYO-BREHM for short).

WeLCoMe

EMB

• Design and construction of instrument prototypes and

preproduction models, e.g. using sinter technology

• Small-batch production of models

• Design, production and repair of electronic devices

• Scanning of stereoscopic objects

• Optimizing cell transport and cell logistics

• Testing the biocompatibility of novel materials

• Software-based cell analysis and monitoring

• Online monitoring of cell growth and metabolism

• Functionalized surfaces and scaffolds

• Coating of transplants and other objects with cells

• Time lapse microscopy

CeLL teChnoLogy

• Stem cell differentiation protocols

• Organotypical cell culture systems, e.g. skin, heart, brain

• Cellular model systems for clinical and applied research

• Cellular test systems, e.g. cytomodulation, cytotoxicity

• Evaluation of cell therapies in animal models, e.g.

wound healing

• Testing of nanomaterials and cell behaviour

• Non-invasive electrophysiological characterization

of cells

• Electroporation and generation of transgenic cell lines

• Protein analysis by high resolution immunofluorescence

microscopy, timelapse microscopy

• Automated nucleic acid isolation

• Quantitative gene expression analysis

• Enzyme-linked immunoadsorption analysis

• Microscopical analysis of native and fixed tissue sections

CeLL DIffeRentIAtIon AquAtIC CeLL teChnoLogy

• Primary cell isolates from aquatic organisms

• Isolation, propagation and differentiation of stem cells

from aquatic organisms for use in biotechnology, forage

industry and medical research

• Cell biological and molecular biological characterization

of long-term cell cultures from aquatic organisms

• Testing of monoclonal and polyclonal antibodies for

aquatic species

• Cellular test systems, e.g. cytomodulation, cytotoxicity

• Monitoring and influence of water quality on aquatic

organisms

• Online monitoring models for aquacultures

• Algae products

• Biomass production using fish cells

• Investigating the regenerative capacity of fish tissues

• In vitro manipulation of fish cells and eggs

• Spontaneously contracting cell aggregates from fish

larvae

CentRAL SeRVICeS LAb

• Isolation and expansion of cells from different tissues and

species, including cells from various domestic and game

animals

• Testing of cross-reactivity of antibodies on cells from vari-

ous organisms

• Vitality and cytotoxicity testing

• Tissue sections using microtome, cryotome and vibratome

• Generation of three-dimensional cell aggregates

CeLL bAnk foR WILDLIfe AnD Zoo AnIMALS ‚ALfReD bRehM‘

Proliferative cell cultures from various animals for research

and development

• Cell culture from currently about 100 species in stock*

• Long-term cryogenic storage of cells

*Please inquire for updates

pRoDuCtS AnD SeRVICeS offeReD by the gRoupS of

pRototype AnD tooL buILDIng