Control of Breathing and Apnea of PrematurityBradley Thach, MD

Outline1) Control of Respiration Basics a) Brain stem respiration centers b) Periferal and central chemoreceptors c) Pulmonary mechano receptors

2) Apnea in Neonates a) Obstructive Apnea micrognathia and other anatomical abnormalities b) Apnea of Prematurity terminology two primary mechanisms: breath holding, reflex apnea c) Laryngeal chemoreflex apnea d) Role of sleep in apnea and mechanisms of recovery from sleep apnea

Outline

1) Control of Respiration Basics a) Brain stem respiration centers b) Periferal and central chemoreceptors c) Pulmonary mechano receptors

2) Apnea in Neonates a) Obstructive Apnea micrognathia and other anatomical abnormalities b) Apnea of Prematurity terminology two primary mechanisms: breath holding, reflex apnea c) Laryngeal chemoreflex apnea d) Role of sleep in apnea and mechanisms of recovery from sleep apnea

Outline

1) Control of Respiration Basics a) Brain stem respiration centers b) Periferal and central chemoreceptors c) Pulmonary mechano receptors

2) Apnea in Neonates a) Obstructive Apnea micrognathia and other anatomical abnormalities b) Apnea of Prematurity terminology two primary mechanisms: breath holding, reflex apnea c) Laryngeal chemoreflex apnea d) Role of sleep in apnea and mechanisms of recovery from sleep apnea

Outline

1) Control of Respiration Basics a) Brain stem respiration centers b) Periferal and central chemoreceptors c) Pulmonary mechano receptors

2) Apnea in Neonates a) Obstructive Apnea micrognathia and other anatomical abnormalities b) Apnea of Prematurity terminology two primary mechanisms: breath holding, reflex apnea c) Laryngeal chemoreflex apnea d) Role of sleep in apnea and mechanisms of recovery from sleep apnea

Outline

1) Control of Respiration Basics a) Brain stem respiration centers b) Periferal and central chemoreceptors c) Pulmonary mechano receptors

2) Apnea in Neonates a) Obstructive Apnea micrognathia and other anatomical abnormalities b) Apnea of Prematurity terminology two primary mechanisms: breath holding, reflex apnea c) Laryngeal chemoreflex apnea d) Role of sleep in apnea and mechanisms of recovery from sleep apnea

Outline

1) Control of Respiration Basics a) Brain stem respiration centers b) Periferal and central chemoreceptors c) Pulmonary mechano receptors

2) Apnea in Neonates a) Obstructive Apnea micrognathia and other anatomical abnormalities b) Apnea of Prematurity terminology two primary mechanisms: breath holding, reflex apnea c) Laryngeal chemoreflex apnea d) Role of sleep in apnea and mechanisms of recovery from sleep apnea