coopersmith cv april 2012 - pwr new · pdf fileawards & honors: 1987 phi beta kappa 1996...

CURRICULUM VITAE

Name: Craig Michael Coopersmith, MD

Work Address: 101 Woodruff Circle

Suite WMB 5105

Atlanta, GA 30322

Phone (404) 727-4273

Fax (404) 727-3660

[email protected]

Home Address: 2247 Dogwood Lane

Atlanta, GA 30345

(314) 863-0350

Date of Birth: August 19, 1965

Place of Birth: New York, New York

Family: Wife, Lois Spritzer

Children, Zachary Alex Coopersmith (Born 12/99)

Talia Naomi Coopersmith (Born 12/01)

Education:

1987 B.A., Magna Cum Laude, University of Pennsylvania

1991 M.D., University of Pennsylvania School of Medicine

Post-Graduate Training:

1991-1992 Intern, Department of Surgery, Barnes Hospital

1992-1993 Junior Assistant Resident, Department of Surgery, Barnes Hospital

1993-1996 Research Fellow, Washington University School of Medicine

1997 (1/1-7/1) Second Year Assistant Resident, Department of Surgery, Barnes-Jewish Hospital

1997-1998 Third Year Assistant Resident, Department of Surgery, Barnes-Jewish Hospital

1998- 1999 Chief Resident, Department of Surgery, Barnes-Jewish Hospital

1999-2000 Fellow, Surgical Critical Care, Washington University School of Medicine

2012 Woodruff Leadership Academy, Woodruff Health Sciences Center, Atlanta, GA

Medical Boards & Licensure:

1992 Diplomate, National Board of Medical Examiners

1995 Missouri State Medical License, #MD106960

2009 Georgia State Medical License #063310

Professional Certification:

2000 Diplomate, American Board of Surgery

2001 Added qualifications in Surgical Critical Care, American Board of Surgery

2002 Fellow, The American College of Surgeons (FACS)

2003 Fellow, The American College of Critical Care Medicine (FCCM)

2009 Recertified, American Board of Surgery (General Surgery)

2010 Recertified, American Board of Surgery (Surgical Critical Care)

Academic Appointments:

2000-2004 Assistant Professor of Surgery; Burn, Trauma, Surgical Critical Care Section,

Division of General Surgery, Washington University School of Medicine

2000-2009 Attending Physician, Barnes-Jewish Hospital

2001-2004 Assistant Professor of Anesthesiology, Washington University School of

Medicine

2001-2003 Associate Director, Surgical Critical Care Fellowship, Washington University

School of Medicine

2001-2009 Associate Director, Anesthesiology Critical Care Medicine Fellowship,

Washington University School of Medicine

2003-2009 Director, Surgical Critical Care Fellowship, Washington University School of

Medicine

2003-2009 Director of General Surgery Resident Research, Washington University School of

Medicine

2004-2009 Associate Professor of Surgery; Burn, Trauma, Surgical Critical Care Section,

Division of General Surgery, Washington University School of Medicine

2004-2009 Associate Professor of Anesthesiology, Washington University School of

Medicine

2009 (7/1-10/31) Professor of Surgery, Washington University School of Medicine

2006-2009 Co-Director, Surgical Intensive Care Unit, Barnes-Jewish Hospital

2007-2009 Division of Biology and Biomedical Sciences (Molecular Cell Biology Program),

Washington University School of Medicine

2009-2010 Professor of Surgery (Visiting), Emory University School of Medicine

2010-present Professor of Surgery, Emory University School of Medicine

2009-present Director, Surgical Intensive Care Unit, Emory University Hospital

2009-present Associate Director, Emory Center for Critical Care

Awards & Honors:

1987 Phi Beta Kappa

1996 Trainee Investigator Award for Excellence in Scientific Research, American Society for

Clinical Investigation Biomedicine ‘96 Medical Research from Bench to Bedside.

1997 Samuel A. Wells, Jr. Resident Research Award, Washington University School of

Medicine

1998 Alpha Omega Alpha

2000 Founder’s Grant for Training in Critical Care Research, Society of Critical Care Medicine

2000 Barnes-Jewish Hospital Team Quality Improvement Award (Blodstream Infection Team)

2002 Caring Spirit Award, Barnes-Jewish Hospital

2002 BJC HealthCare System Team Quality Improvement Award (Clinical Effectiveness of

Phosphorus Repletion Guideline in the SICU)

2002-2007 Presidential Citation, Society of Critical Care Medicine

2003 Research Citation Award (given to top 5 posters) Society of Critical Care Medicine

2005 BJC HealthCare System Team Quality Improvement Award (Ventilator Associated

Pneumonia Prevention Team)

2001, 2004, 2006, 2008 Teacher of the Year, Surgical and Burn/Trauma Intensive Care Unit, Barnes-

Jewish Hospital

2008, 2009 St. Louis “Best Doctors”, St. Louis Magazine

2009 Outstanding Faculty Mentor Award, Washington University Postdoctoral Society

2009-2011 Best Doctors in America

Professional Organizations:

American Surgical Association

American Medical Association

American College of Surgeons

Association for Academic Surgery

Shock Society

Society of Critical Care Medicine

Society of University Surgeons

Surgical Biology Club II

Surgical Infection Society

Peer Review:

Editoral Boards/Consultants/Guest Editor Positions:

Editor, Critical Connections (2012-present)

Editorial Board, Journal of the American College of Surgeons (2011-present)

Editorial Board, Journal of Surgical Research (2007-present)

Editorial Board, Critical Care Medicine (2006-present)

Editorial Board, Shock (2005-present)

Editorial Consultant Physicians' Information and Education Resource American College of Physicians

(2007-2011)

Guest editor, Current Opinions in Critical Care, The Gastrointestinal System (2009)

Peer review governmental/certifying boards

United States:

NIH, Center for Scientific Review, Surgery, Anesthesiology and Trauma Study Section (2011-present)

NIH, Center for Scientific Review, Special Study Section ZRG 1 SBIB-E, chair (2010), ad hoc reviewer

(2010, 2009, 2008, 2006x2, 2005)

NIH, Center for Scientific Review, Special Study Section ZGM, PPBC-0, ad hoc reviewer (2010)

American Institute of Biological Sciences on behalf of US Army Medical Research and Materiel Command

(2009)

American Board of Surgery, Associate Examiner for Certifying Examination (2006)

International:

Grant Review, Austrian Science Fund (2011)

Grant Review, Medical Research Council (UK), (2010)

College of Reviewers, Canada Research Chairs Program (2008)

Grant review, National Health Laboratory Service Research Trust Grants (South Africa) (2007)

Grant review, Netherlands Organisation for Health Research and Development (2006)

Journal review

Reviewer, American Journal of Infection Control

Reviewer, American Journal of Pathology

Reviewer, American Journal of Physiology Gastrointestinal and Liver Physiology

Reviewer, American Journal of Physiology Regulatory, Integrative and Comparative Physiology

Reviewer, American Journal of Respiratory and Critical Care Medicine

Reviewer, Anesthesiology

Reviewer, Annals of Surgery

Reviewer, Archives of Surgery

Reviewer, BMC Infectious Diseases

Reviewer, BMC Microbiology

Reviewer, Brain, Behavior and Immunity

Reviewer, Chest

Reviewer, Critical Care

Reviewer, Critical Care Medicine

Reviewer, Critical Care Research and Practice

Reviewer, Digestive Diseases and Sciences

Reviewer, Expert Opinion On Investigational Drugs

Reviewer, Free Radical Biology and Medicine

Reviewer, Journal of the American College of Surgeons

Reviewer, Journal of the American Medical Association

Reviewer, Journal of Gerontology: Biological Sciences

Reviewer, Journal of Immunology

Reviewer, Journal of Infectious Diseases

Reviewer, Journal of Intensive Care Medicine

Reviewer, Journal of Leukocyte Biology

Reviewer, Journal of Pharmacology and Experimental Therapeutics

Reviewer, Journal of Surgical Research

Reviewer, Infection and Immunity

Reviewer, Intensive Care Medicine

Reviewer, International Journal of Radiation Biology

Reviewer, Medicine

Reviewer, Neurogastroenterology and Motility

Reviewer, Shock

Reviewer, Surgical Infections

Reviewer, World Journal of Surgery

Medical Center Committees:

Washington University/Barnes-Jewish Hospital

2000-2009 Transfusion Committee

2001-2009 Graduate Medical Education Committee

2002-2009 SICU Outcomes Committee

2003-2009 Antibiotic Utilization Review Committee

2000-2002 SICU Bloodstream Infection Committee

2002-2005 SICU Insulin/Blood Glucose Control Committee

2003-2009 Director of General Surgery Resident Research, Washington University School of

Medicine

2004-2005 SICU Ventilator Associated Pneumonia Prevention Committee

2005 Medication Reconciliation Committee (ad hoc member)

2006-2009 Institutional Review Board

2006-2009 Barnes-Jewish Hospital Critical Care Committee

2006-2008 Chair-elect Critical Care Committee

2008-2009 Chair, Critical Care Committee

2006 Data Safety Monitoring Board Siteman Cancer Center (for study HSC#02-0788)

2007 Dept. of Anesthesiology Ad Hoc Committee on Appointments and Promotions

2007-2009 KL2 (formerly K12) Clinical Scholars Selection Committee

2007 Institute of Clinical and Translational Sciences Novel Methodologies and Pilot

Studies Program Review Committee

2008-2009 Disclosure Review Committee

2008 Clinical Research Training Center Post-doctoral Program Selection Committee

Emory University and Emory Healthcare

2009-present Chair, Emory University Hospital Critical Care Committee

2011-present CLABSI team, Emory University Hospital

2011-present Medical Student Research Committee

2011-present Scientific Advisory Committee, Atlanta Clinical and Translational Science Institute

2012-present Interview committee for VP of Operations Emory University Hospital

Professional Society Committee Memberships:

Society of Critical Care Medicine

2002-2006 Program Committee

2004-2005 Co-Chair Program Committee for 2005 Annual Congress (> 5000 attendees)

2002-2007 Research Committee

2004-2005 Chair Research Committee

2004-2011 Chair Task Force on Future of Research in SCCM

2002 Task force to respond to proposed Joint Commission on Hospital Accreditation

ICU measures

2002 Reviewer for Norma J. Shoemaker Grant for Critical Care Nursing Research

2002-2004 Infectious Disease/Critical Care Medicine Ad Hoc Committee

2002-2005 Surgical Section Education Committee

2003-2005 A.S. Leardal Memorial Lecture Award Committee

2004-2005 Co-Chair Laerdal Award Committee

2005-2008 Publications Advisory Committee

2008 Chair, Publications Advisory Committee

2006-present Surgical Section Nominations Committee

2006-2009 American College of Critical Care Medicine Credentials Committee

2008-2009 Surgical Section Secretary/Treasurer

2009-2010 Surgical Section, Chair-Elect

2010-2011 Surgical Section, Chair

2010-present Strategic Planning Committee

2011 Vice chair, strategic planning committee

2011-present Strategic Education Committee

2008-present Council

2012-present Secretary

Shock Society

2002-2005 Rules Committee

2004-2005 Chair, Rules Committee

2005-2010, 2011-presentCouncil

2005-2008 Publications Committee

2005-2008 Chair, Publications Committee

2007-2010 Scientific Program Committee

2009 Co-chair, Program Committee for 2009 Annual Congress

2009-2010 Chair, Program Committee for 2010 Annual Congress

2011-present Clinical Science Representative to Council

Surgical Infection Society

2005-2007 Program Committee

2008-2011 Chair, Fellowship Committee

Society of University Surgeons

2008-2011 Membership Committee

American College of Surgeons

2006-2009 Trauma Committee (Missouri chapter)

Grant Support:

CURRENT (Peer Reviewed)

Funding Agency: National Institutes of Health

Period: 9/6/05-8/31/14

Grant Title: Mechanisms of Intestinal Apoptosis in Sepsis and Shock (R01 GM072808)

Principal Investigator: Craig Coopersmith

Total Direct Costs: $693,000 first funding cycle, $960,000 second funding cycle


Period: 7/1/11-6/30/16

Grant Title: Critical Care Training Grant (T32GM095442)


Total Direct Costs: $1,078,128

Funding Agency: Emory Alcohol and Lung Biology Center (which is funded by the NIH)

Period: 1/1/12-12/31/12

Grant Title: Chronic Alcohol Ingestion and Sepsis (Pilot Project 1, P50AA013757)

Total Direct Costs: $38,000

Funding Agency: James S. McDonnell Foundation

Period: 12/1/07-11/30/12

Grant Title: Cognitive Complexity and Error in Critical Care (JSMF 220020152Collaborative

Award)

Principal Investigator: Timothy Buchman

Co-investigator: Craig Coopersmith


Trainees who applied and receive external funding for projects in Dr. Coopersmith’s lab are listed at

bottom of CV.

PAST (Peer reviewed)


Period: 7/1/02 – 2/28/11

Grant Title: Gut Epithelial Apoptosis in Shock and Sepsis (R01 GM66202)


Total Direct Costs: $651,000 first funding cycle, $840,000 second funding cycle


Period: 9/15/09-2/28/11

Grant Title: Collaborative Science Supplement (supplement to Gut Epithelial Apoptosis in

Shock and Sepsis, R01 GM66202 to fund collaboration with Nicholas Davidson,

MD)




Period: 9/1/07-10/31/09

Grant Title: The Function of TREM-1 in Sepsis (R01 GM077279)

Principal Investigator: Marco Colonna



Funding Agency: Centers for Disease Control and Prevention

Period: 1/29/01-10/31/09

Study: Washington University & BJC Epi-Center for Prevention of Healthcare-

Associated Infection (1U01CI000333-01)

Principal Investigator: Victoria Fraser


Total funding: $631,330/year


Period: 5/28/09-8/31/09

Grant Title: Research Supplement to Promote Diversity in Health-Related Research

(supplement to Gut Epithelial Apoptosis in Shock and Sepsis R01 GM66202 to

fund fellowship of Alexandr Samocha)


Total Direct Costs: $5186


Period: 6/1/08-8/31/08


(supplement to Mechanisms of Intestinal Apoptosis in Sepsis and Shock, R01

GM072808-01 to fund fellowship of Alexandr Samocha)


Total Direct Costs: $3723


Period: 7/1/06-5/27/08


(supplement to Mechanisms of Intestinal Apoptosis in Sepsis and Shock, R01

GM072808-01 to fund post-doctoral fellowship of Jessica Clark, PhD)




Period: 9/1/00 – 8/31/05

Grant Title: Intestinal Apoptosis in Shock and Injury (K08 GM00709-01)



Funding Agency: Society of Critical Care Medicine

Period: 7/1/00 – 6/30/01

Grant Title: Intestinal Apoptosis in Shock and Injury


Total funding: $30,000

Funding Agency: Washington University Digestive Diseases Research Cores Center

Period: 1/1/01 – 11/30/01

Grant Title: Intestinal Apoptosis in Ischemia/Reperfusion and Sepsis



Funding Agency: Centers for Disease Control and Prevention

Period: 9/1/04-8/31/06 (R01CI000206-01)

Study: Applied Research on Antimicrobial Resistance: Estimates of Economic Cost for

Antimicrobial Resistant Human Pathogens of Public Health Importance




Funding Agency: Agency for Healthcare Research and Quality

Period: 9/30/01 - 9/29/04

Study: Surveillance, analysis, and interventions to improve patient safety

(1/U18/HS11898-01)



Total funding: $1,935,551

Publications:

1. Kim SH, Roth KA, Coopersmith CM, Gordon JI. Expression of wild-type and mutant

simian virus 40 large tumor antigens in villus-associated enterocytes of transgenic mice. Proceedings of

the National Academy of Sciences of the United States of America 91:6914-6918, 1994.

2. Chandrasekaran C, Coopersmith CM, Gordon JI. Use of normal and transgenic mice

to examine the relationship between terminal differentiation of intestinal epithelial cells and accumulation

of their cell cycle regulators. Journal of Biological Chemistry 271:28414-28421, 1996.

3. Coopersmith CM, Gordon JI. Gamma-ray induced apoptosis in transgenic mice with

proliferative abnormalities in their intestinal epithelium: re-entry of villus enterocytes into the cell cycle

does not affect their radioresistance but enhance the radiosensitivity of the crypt by inducing p53.

Oncogene 15:131-141, 1997.

4. Coopersmith CM, Chandrasekaran C, McNevin MS, Gordon JI. Bi-transgenic mice reveal that K-

rasVal12 augments a p53-independent apoptosis when small intestinal villus enterocytes re-enter the cell

cycle. Journal of Cell Biology 138:167-179, 1997.

5. Coopersmith CM, Lowell JA. Surgery of the small intestine. Current Opinions in

Gastroenterology 15:146-150, 1999.

6. Lowell JA, Coopersmith CM, Shenoy S, Howard TK. Unusual presentations of non-

mycotic hepatic artery pseudoaneurysms after liver transplantation. Liver Transplantation & Surgery

5:200-203, 1999.

7. Coopersmith CM, O’Donnell D, Gordon JI. Forced expression of Bcl-2 inhibits

ischemia-reperfusion induced apoptosis in the intestinal epithelium of transgenic mice. American Journal

of Physiology Gastrointestinal and Liver Physiology 276:G677-686, 1999.

8. Coopersmith CM, Brennan DC, Miller B, Wang C, Hmiel P, Shenoy S, Ramachandran V,

Jendrisak MD, Ceriotti CS, Mohanakumar T, Lowell JA. Renal transplantation following

previous solid organ transplantation: an 8-year single-center experience. Surgery 130:457-462, 2001.

9. Coopersmith CM, Chang KC, Swanson PE, Tinsley KW, Stromberg PE, Buchman TG, Karl IE,

Hotchkiss RS. Overexpression of Bcl-2 in the intestinal epithelium increases survival in septic mice.

Critical Care Medicine 30:195-201, 2002.

10. Coopersmith CM, Rebmann TL, Zack JE, Ward MR, Corcoran RM, Schallom ME, Sona CS,

Buchman TG, Boyle WA, Polish LB, Fraser VJ. Effect of an education program on decreasing catheter-

related bloodstream infections in the surgical intensive care unit. Critical Care Medicine 30: 59-64, 2002.

11. Hotchkiss RS, Tinsley RW, Swanson PE, Grayson MH, Osborne DF, Wagner TH, Cobb JP,

Coopersmith C, Karl IE. Depletion of dendritic cells but not macrophages in patients with sepsis. Journal

of Immunology 168: 2493-2500, 2002.

12. Coopersmith CM, Stromberg PE, Dunne WM, Davis CG, Amiot DM, Buchman TG, Karl IE,

Hotchkiss RS. Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-

induced sepsis. Journal of the American Medical Association 287:1716-1721, 2002.

13.Copersmith CM, Lowell JA, Hasam A, Howard TK. Hepatocellular carcinoma in a patient

with focal nodular hyperplasia. HPB, 4: 135-138, 2002.

14. Zack JE, Garrison T, Trovillion E, Clinkscale D, Coopersmith CM, Fraser VJ, Kollef MH. Effect of an

education program aimed at reducing the occurrence of ventilator-associated pneumonia. Critical Care

Medicine, 30: 2407-2412, 2002.

15. Turnbull IR, Wizorek JJ, Osborne D, Hotchkiss RS, Coopersmith CM, Buchman TG. Effects of age

on mortality and efficacy in cecal ligation and puncture. Shock, 19:310-313, 2003 -- lead (cover)

manuscript.

16. Coopersmith CM, Amiot DM, Stromberg PE, Dunne WM, Davis CG, Osborne DF, Karl IE, Hotchkiss

RS, Buchman TG. Antibiotics improve survival and alter the inflammatory profile in a murine model of

sepsis from Pseudomonas aeruginosa pneumonia. Shock, 19:408-414, 2003.

17. Husain KD, Coopersmith CM. Role of intestinal epithelial apoptosis on survival. Current Opinions in

Critical Care, 9:159-163, 2003.

18. Coopersmith CM, Stromberg PE, Davis CG, Dunne WM, Amiot DM, Karl IE, Hotchkiss RS,

Buchman TG. Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and

induces gut epithelial cell cycle arrest. Critical Care Medicine, 31:1630-1637, 2003 -- leading clinical

investigation (cover).

19. Husain KD, Coopersmith CM. Intestinal apoptosis in shock and sepsis. Advances in Sepsis, 3: 2-7,

2003.

20. Husain KD, Stromberg PE, Javadi, P, Buchman TG, Karl IE, Hotchkiss RS, Coopersmith CM. Bcl-2

inhibits gut epithelial apoptosis induced by acute lung injury in mice but has no effect on survival. Shock,

20:437-443, 2003.

21. Ali S, Freeman BD, Coopersmith CM. Abdominal compartment syndrome in a patient resulting from

pneumothorax. Intensive Care Medicine, 29:1614, 2003.

22. Taylor BE, Huey WY, Buchman TG, Boyle WA, Coopersmith CM. Treatment of hypophosphatemia

using a protocol based on patient weight and serum phosphorus level in a surgical intensive care uint.

Journal of the American College of Surgeons, 198:198-204, 2004.

23. Coopersmith CM, Zack JE, Ward MR, Schallom ME, Sona CS, Everett S, Huey W, Garrison T,

McDonald J, Buchman TG, Boyle WA, Fraser VJ, Polish LB. The impact of bedside behavior on catheter-

related bacteremia in the intensive care unit.Archives of Surgery, 139:131-136, 2004 (cover).

24. Turnbull IR, Javadi P, Buchman TG, Hotchkiss RS, Karl IE, Coopersmith CM. Antibiotics improve

survival in sepsis independent of injury severity but do not change mortality in mice with markedly

elevated IL-6 levels Shock, 21:121-125, 2004 -- lead (cover). 25. Coopersmith, CM. Mitochondrial membrane dysfunction in endotoxemia: The difference between

what's in and what's out, Critical Care Medicine, 32:607-609, 2004.

26. Javadi P, Buchman TG, Stromberg PE, Husain KD, Dunne WM, Woolsey CA, Turnbull IR, Hotchkiss

RS, Karl IE, Coopersmith CM. Exogenous iron following cecal ligation and puncture increases mortality

in mice and is associated with an increase in gut epithelial and splenic apoptosis, Critical Care Medicine,

32:1178-1185, 2004 (cover).

27. Wizorek J, Coopersmith CM, Laramie JM, Tong A, Stromberg PE, Hotchkiss RS, Buchman TG,

Cobb JP. Sequence makes a difference: Paradoxical effects of heat shock in vivo, Shock, 22:229-233,

2004.

28. Turnbull IR, Buchman TG, Javadi P, Woolsey CA, Hotchkiss RS, Karl IE, Coopersmith CM. Age

disproprotionately increases sepsis-induced apoptosis in the spleen and gut epithelium. Shock, 22:364-

368, 2004 – lead (cover) manuscript. 29. Coopersmith CM. Levosimendan and gut mucosal blood flow – not all inotropes are created equal.

Critical Care Medicine, 33:246, 2005.

30. Hotchkiss RS, Osmon SB, Chang KC, Wagner TH, Roy S, Coopersmith CM, Karl IE. Accelerated

lymphocyte death in sepsis occur by both the death receptor and mitochondrial mediated pathways.

Journal of Immunology, 174: 5110-5118, 2005.

31. Carroll P, Saenz Robles MT, Markovics JM, Pope H, Coopersmith CM, Pipas J. Loss of p53 function

is not essential for progression from intestinal hyperplasia to dysplasia. Journal of Virology, 79:7492-

7502, 2005.

32. Javadi P, Buchman TG, Stromberg PE, Turnbull IR, Hotchkiss RS, Karl IE, Coopersmith CM.

Iron dysregulation combined with aging prevent sepsis-induced apoptosis, Journal of Surgical Research,

128:37-44, 2005.

33. Hotchkiss RS, Coopersmith CM, Karl IE. Prevention of lymphocyte apoptosis – a potential therapy of

sepsis? Clinical Infectious Diseases, 417:S465-469, 2005.

34. Husain KD, Stromberg PE, Woolsey CA, Turnbull IR, Dunne WM, Javadi P, Buchman TG, Karl IE,

Hotchkiss RS, Coopersmith CM. Mechanisms of decreased intestinal epithelial proliferation and

increased apoptosis in murine acute lung injury. Critical Care Medicine, 33:2350-2357, 2005.

35. Vyas D, Javadi P, DiPasco P, Buchman TG, Hotchkiss RS, Coopersmith CM. Early antibiotic

administration but not antibody therapy directed against IL-6 improves survival in septic mice predicted to

die based upon high IL-6 levels American Journal of Physiology Regulatory, Integrative and Comparative

Physiology , 289:R1048-1053, 2005.

36. Freeman BD, Borecki IB, Coopersmith CM, Buchman, TG. Relationship between tracheostomy

timing and duration of mechanical ventilation in critically ill patients, Critical Care Medicine, 33:2513-2520,

2005.

37. McConnell, KW, Coopersmith CM. Epithelial cells. Critical Care Medicine, 33:S520-522, 2005.

38. Taylor BE, Schallom ME, Sona CS, Buchman TG, Boyle WA, Mazuski JE, Schuerer DJ, Thomas JM,

Kaiser C, Huey WY, Ward MR, Zack JE, Coopersmith CM. Efficacy and safety of an insulin infusion

protocol in a surgical ICU. Journal of the American College of Surgeons, 202:1-9, 2006.

39. Woolsey CA, Coopersmith CM. Vasoactive drugs and the gut - is there anything new? Current

Opinions in Critical Care, 12: 155-159, 2006.

40. Freeman BD, Kennedy CR, Coopersmith CM, Zehnbauer BA, Buchman TG. Attitudes regarding

genetic research and testing held by individuals providing substituted judgment for critically ill patients.

Critical Care Medicine 34: 986-994, 2006.

41. Hotchkiss RS, McConnell KW, Kelley K, Davis CG, Chang KC, Schwulst S, Dunne JC, Dietz GPH,

Bahr M, McDunn JE, Karl IE, Coopersmith CM, Piwnica-Worms, D. Protection against sepsis-induced

lymphocyte apoptosis via in vivo delivery of Tat fusion compounds. Journal of Immunology, 176: 5471-

5479, 2006.

42. Schuerer DJ, Nast PA, Harris CB, Krauss MJ, Dunagan WC, Coopersmith CM, Ward M, Fraser V.

Reporting of patient safety events in a surgical intensive care unit. Journal of the American College of

Surgeons, 202: 881-887, 2006.

43. Robertson CM, Coopersmith CM. Systemic Inflammatory Response Syndrome. Microbes and

Infection, 8: 1382-1389, 2006.

44. Warren DK, Jones RM, Coopersmith CM, Merz LR, Zack JE, Fraser VJ. The Epidemiology of

Methicillin-resistant Staphylococcus aureus in a Surgical Intensive Care Unit. Infection Control and

Hospital Epidemiology, 27: 1032-1040, 2006.

45. Freeman BD, Kennedy CR, Coopersmith CM, Zehnbauer BA, Buchman TG. Patients' and

surrogates' perspective on research and testing in critical care. Critical Care Medicine 35: 328-329, 2007.

46. Schwulst SJ, Davis CG, Coopersmith CM, Hotchkiss RS. Adoptive transfer of dying cells causes

bystander-induced apoptosis. Biochemical and Biophysical Research Communication, 353:780-785,

2007.

47. Warren DK, Guth RM, Coopersmith CM, Merz LR, Zack JE, Fraser VJ. The impact of an MRSA

active surveillance program on contact precaution utilization in a surgical intensive care unit. Critical Care

Medicine, 35:430-434, 2007.

48. McMullen KM, Zack J, Coopersmith CM, Kollef M, Dubberke E, Warren DK. The Use of Hypochlorite

Solution to Lower Rates of Clostridium difficile – Associated Diarrhea. Infection Control and Hospital

Epidemiology, 28:205-207, 2007.

49. McConnell KW, Muenzer JT, Chang KC, Davis CG, McDunn JE, Coopersmith CM, Hilliard CA,

Hotchkiss RS, Grigsby PW, Hunt CR. Anti-apoptotic peptides protect against radiation induced cell death.

Biochemical and Biophysical Research Communication, 355:501-507, 2007.

50. Harris CB, Krauss MJ, Nast PA, Kollef MH, Jacobsohn E, Avidan M, Coopersmith CM, Hill P,

Dunagan WC, Fraser, VJ. Patient safety event reporting in critical care – an observational study of three

intensive care units. Critical Care Medicine, 35:1068-1076, 2007.

51. Vyas D, Robertson CM, Stromberg PE, Martin J, Dunne WM, Houchen CW, Barrett TA, Ayala A, Perl

M, Buchman TG, Coopersmith CM. Epithelial apoptosis in mechanistically distinct methods of injury in

the murine small intestine. Histology and Histopathology, 22:623-630, 2007.

52. Robertson CM, Klingensmith ME, Coopersmith CM. Long-term outcomes of performing a post-

doctoral research fellowship during general surgery residency, Annals of Surgery, 245:516-523, 2007.

53. Clark JA, Coopersmith CM. Just the right amount of JNK – how NFkB and downstream mediators

prevent burn-induced intestinal injury, Critical Care Medicine, 35:1433-1434, 2007.

54. Byrnes MC, Coopersmith CM. Prevention of catheter-related bloodstream infection. Current Opinions

in Critical Care, 13:411-415, 2007.

55. Jones JC, Rogers TJ, Brookmeyer P, Dunne WM, Storch GA, Coopersmith CM, Fraser VJ, Warren

DJ. Mupirocin resistance in methicillin-resistant Staphylococcus aureus from a surgical intensive care

unit, Clinical Infectious Diseases, 45:541-547, 2007.

56. Piel DA, Grubner PJ, Weinheimer C, Courtois MR, Robertson CM, Coopersmith CM, Deutschman

CS, Levy RJ. Mitochondrial resusciation with exogenous cytochrome c in the septic heart, Critical Care

Medicine, 35:2120-2127, 2007.

57. Schuerer DJE, Zack JE, Thomas J, Borecki IB,Sona CS, Schallom ME, Venker M, Nemeth JL, Ward

M, Verjan L, Warren DK, Fraser VJ, Mazuski J, Boyle WA, Buchman TG, Coopersmith CM. The effect of

chlorhexidine/silver sulfadiazine-impregnated central venous catheters in an ICU with low bloodstream

infection rates following implementation of a successful education program: a before-after trial. Surgical

Infections, 8:445-454, 2007.

58. Clark JA, Coopersmith CM. Intestinal crosstalk – a new paradigm for understanding the gut as the

“motor” in critical illness. Shock, 28:384-393, 2007.

59. Graham DB, Robertson CM, Bautista J, Diacovo MJ, Montgrain V, Lam SK, Cremasco V, Faccio R,

Dunne WM, Coopersmith CM, Swat W. Neutrophil-mediated oxidative burst and host defense against

Staphylococcal pneumonia and Pseudomonas aeruginosa are controlled by a vav-PLCγ2 signaling axis.

Journal of Clinical Investigation, 117:3445-3452, 2007.

60. Rajan S, Vyas D, Clark A, Woolsey CA, Clark JA, Hotchkiss RS, Buchman TG, Coopersmith CM.

Intestine-specific overexpression of IL-10 improves survival in polymicrobial sepsis. Shock, 29:483-489,

2008.

61. Clark JA, Clark AT, Hotchkiss RS, Buchman TG, Coopersmith CM. Epidermal growth factor

treatment decreases mortality and is associated with improved gut integrity in sepsis. Shock, 30:36-42,

2008.

62. Schwulst SJ, Muenzer JT, Chang KC, Brahmbatt TS, Coopersmith CM, Hotchkiss RS. Lymphocyte

phenotyping to distinguish septic from nonseptic critical illness. J Am Coll Surg. 206:335-342, 2008.

63. McDunn JE, Husain KD, Polpitiya AD, Burykin A, Rua J, Zhang W, Coopersmith CM, Dunne WM,

Colonna M, Ghosh B, Stormo GD, Cobb JP. Plasticity of the systemic inflammatory response to critical

illness, PloS One, 13:3,e1564, 2008.

64. Robertson TR, Sona C, Schallom ME, Buckles M, Cracchiolo L, Schuerer DJE, Coopersmith CM,

Song F, Buchman TG. Increase in extubation rates with implementation of a daily spontaneous breathing

trial protocol. Journal of the American College of Surgeons, 206:489-495, 2008.

65. Schuerer DJE, Kolovos NS, Boyd KV, Coopersmith CM. Extracorporeal memberane oxygenation:

current clinical practice, coding and reimbursement. Chest, 134:179-184, 2008.

66. Freeman BD, Kennedy C, Robertson E, Coopersmith CM, Schuerer DJE, Buchman TG.

Tracheostomy protocol: experience with development and potential utility Critical Care Medicine,

36:1742-1748, 2008.

67. Robertson CM, McConnell KW, Dunne WM, Boody B, Brahmbhatt T, Diacovo MJ, Van Rooijen N,

Hogue LA, Cannon CL, Buchman TG, Hotchkiss RS, Coopersmith CM. Neutrophil Depletion Causes a

Fatal Defect in Murine Pulmonary Staphylococcus aureus Clearance. Journal of Surgical Research,

150:278-85, 2008.

68. Checchia PA, Schierding W, Polpitiya A, Dixon D, MacMillan S, Muenzer J, Coopersmith CM,

Buchman TG, Cobb TG. Myocardial transcriptional profiles in a murine model of sepsis: evidence for the

importance of age. Pediatric Critical Care Medicine, 9:530-5, 2008.

69. Freeman BD, Dixon DJ, Coopersmith CM, Zehnbauer BA, Buchman TG. Pharmacoepidemiology of

QT-prolonging drug administration in critically ill patients, Pharmacoepidemiology and Drug Safety,

17:971-81, 2008.

70. Sona CS, Zack JE, Schallom ME, McSweeney M, McMullen K, Thomas J, Coopersmith CM, Boyle

WA, Buchman TG, Mazuski JE, Schuerer DJE. The impact of a simple, low-cost oral care protocol on

ventilator-associated pneumonia rates in a surgical intensivce care unit, Journal of Intensive Care

Medicine, 24:54-62, 2009.

71. Robertson CM, Klingensmith ME, Coopersmith CM. Prevalence and cost of full-time research

fellowships during general surgery residency – a national survey, Annals of Surgery, 249:155-161, 2009.

Reply to letter to the editor regarding this manuscript in press, Annals of Surgery.

72. Fox AC, Coopersmith CM. Erythropoietin in sepsis: a new use for a familiar drug? Critical Care

Medicine, 37:1138-1139, 2009.

73. Goede MR, Coopersmith CM. Catheter-related bloodstream infection. Surgical Clinics of North

America, 89:463-474, 2009

74. Turnbull IR, Clark AT, Stromberg PE, Dixon DJ, Woolsey CA, Davis CG, Hotchkiss RS, Buchman TG,

Coopersmith CM. Effects of aging on the immunopathological response to sepsis, Critical Care

Medicine, 37:1018-1023, 2009.

75. Stromberg PE, Woolsey CA, Clark AT, Clark JA, Turnbull IR, McConnell KW, Chang KC, Chung C,

Ayala A, Buchman TG, Hotchkiss RS, Coopersmith CM. CD4+ lymphocytes control gut epithelial

apoptosis and mediate survival in sepsis, FASEB Journal, 23: 1817-1825, 2009.

76. Hotchkiss RS, Coopersmith CM, McDunn JE, Ferguson TA, Immunosuppression in critical illness

mechanistic insights, Nature Medicine, 15: 496-497, 2009.

77. Brahmamdam P, Watanabe E, Unsinger J, Dixon D, Hoekzema A, Zhou T, Chang KC, McDonough J,

Holemon H, Heidel JD, Coopersmith CM, McDunn JE, Hotchkiss RS Targeted delivery of siRNA to cell

death proteins in sepsis. Shock, 32:131-9, 2009.

78. Byrnes MC, Schuerer DJE, Schallom ME, Sona CS, Mazuski JE, Taylor BE, McKenzie W, Thomas

JT, Emerson JS, Nemeth JL, Bailey RA, Boyle WA, Buchman TG, Coopersmith CM. Implementation of a

mandatory checklist of protocols and objectives improves compliance with a wide range of evidence-

based ICU practices, Critical Care Medicine, 37: 2775-2785, 2009.

79. Freeman BD, Kennedy C, Coopersmith CM, Buchman TG. Examination of patient-independent

factors affecting tracheostomy practice in an academic surgical intensive care unit, Critical Care

Medicine, 37: 3070-3078, 2009.

80. Clark JA, Gan H, Samocha AJ, Fox AC, Buchman TG, Coopersmith CM. Enterocyte-specific

epidermal growth factor prevents barrier dysfunction and improves mortality in murine peritonitis,

American Journal of Physiology Gastrointestinal and Liver Physiology, 297:G471-9, 2009.

81. McConnell KW, McDunn JE, Clark AT, Dunne WM, Dixon DJ, Turnbull IR, DiPasco PJ, Osberghau

WF, Sherman B, Martin JR, Walter MJ, Cobb JP, Buchman TG, Hotchkiss RS, Coopersmith CM.

Streptococcus pneumoniae and Pseudomonas aeruginosa pneumonia induce distinct local and systemic

inflammatory host responses, Critical Care Medicine, 38: 233-241, 2010.

82. Fox AC, Robertson CM, Belt B, Clark AT, Chang KC, Leahtersich AM, Dominguez JA, Perrone EE,

Dunne WM, Hotchkiss RS, Buchman TG, Linehan DC, Coopersmith CM. Cancer causes increased

mortality and is associated with altered apoptosis in murine sepsis, Critical Care Medicine, e pub ahead

of print.

83. Inoue S, Unsinger J, Davis CG, Muenzer JT, Ferguson TA, Clark AT, Coopersmith CM, McDunn JE,

Hotchkiss RS. IL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves

survival in sepsis, Journal of Immunology, 184:1401-1409, 2010.

84. Muenzer JT, Davis CG, Chang K, Schmidt RE, Dunne WM, Coopersmith CM, Hotchkiss RS.

Characterization and modulation of the immunosuppressive phase of sepsis. Infection and Immunity,

78:1582-1592, 2010.

85. Honda H, Krauss MJ, Coopersmith CM, Kollef MH, Richmond AM, Fraser VJ, Warren DK,

Staphylococcus aureus Colonization and Subsequent Infection in Intensive Care Unit Patients: Does

Methicillin Resistance Matter, Infection Control and Hospital Epidemiology, 31:584-591, 2010.

86. Dominguez, JA, Coopersmith CM, Can We Protect the Gut in Critical Illness: The Role of Growth

Factors and Other Novel Approaches, Critical Care Clinics, 26:549-565, 2010.

87. McConnell KW, Fox AC, Clark AT, Chang NN, Dominguez JA, Farris AB, Buchman TG, Hunt CR,

Coopermsith CM. The role of HSP70 in mediating age-dependent mortality in sepsis, Journal of

Immunology, 186:3718-3725, 2011

88. Pastores SM, O’Connor MF, Kleinpell RM, Napolitano L, Ward N, Bailey H, Mollenkopf FP,

Coopersmith CM. The ACGME Resident Duty-Hour New Standards: History, Changes, and Impact on

Staffing of Intensive Care Units, Critical Care Medicine, 39:2540-2549, 2011.

89. Dominguez JA, Vithayathil, PJ, Khailova L, Lawrance CP, Samocha AJ, Jung E, Leathersich AM,

Dunne WM, Coopersmith CM. EGF enhances intestinal epithelial integrity and improves survival in

Pseudomonas aeruginosa pneumonia, Shock, 36:381-389, 2011.

90. Fox AC, Breed ER, Liang Z, Clark AT, Zee-Cheng BR, Chang KC, Dominguez JA, Jung E, Dunne

WM, Burd EM, Farris AB, Linehan DC, Coopersmith CM. Prevention of lymphocyte apoptosis in septic

mice with cancer increases mortality, Journal of Immunology, 187:1950-1956,2011.

91. Carpenter CR, Griffey RT, Stark S, Coopersmith CM, Gage BF, Physician and Nurse Acceptance of

Geriatric Technicians to Screen for Geriatric Syndromes in the Emergency Department, Western Journal

of Emergency Medicine, 12:489-495, 2011.

92. Jung E, Perrone EE, Liang Z, Breed ER, Dominguez JA, Clark AT, Fox AC, Dunne WM, Burd EM,

Farris AB, Hotchkiss RS, Coopersmith CM. Cecal ligation and puncture followed by MRSA pneumonia

increases mortality in mice and blunts production of local and systemic cytokines, Shock, 37: 85-94,2012.

92. Coopersmith CM, Wunsch, H,. Fink MP, Linde-Zwirble WT, Olsen KM, Sommers,MS, Anand KJS,

Kingsmore SF, Tchorz KM, Angus, DC, Deutschman CS, A comparison of critical care research funding

and the financial burden of critical illness in the United States, Critical Care Medicine, 40:1072-1079,

2012.

93. McConnell KW, Coopersmith CM. Organ failure avoidance and mitigation strategies, Surgical Clinics

of North America, 92:307-319, 2012.

94. Carpenter DL, Gregg SR, Owens DS, Buchman TG, Coopersmith CM. Documentation of patient

care time by nurse practitioners and physician assistants in the intensive care unit, Critical Care, 16:R27,

2012.

95. Perrone EE, Jung E, Dominguez JA, Clark AT, Dunne WM, Burd E, Hotchkiss RS, Buchman TG,

Coopersmith CM. Mechanisms of methicillin-resistant Staphylococcus aureus pneumonia-induced

intestinal epithelial apoptosis, submitted.

96. Ingram TC, Kamat P, Coopersmith CM, Vats A. Intensivist’s perceptions of family centered rounds

and its impact on physician comfort, staff involvement, teaching and efficiency, submitted.

97. Dominguez JA, Samocha AJ, Coopersmith CM. Inhibition of NF-κB in enterocytes exacerbates

sepsis-induced intestinal injury and worsens mortality, submitted.

98. Dominguez JA, Xie Y, Dunne WM, Coopersmith CM, Davidson NO. Intestine-specific Mttp deletion

decreases mortality and prevents sepsis-induced intestinal injury in a model of Pseudomonas aeruginosa

pneumonia, submitted.

99. Benton SM, Liang Z, Hao L, Hebba G, Jones DP, Coopersmith CM, Ziegler TR. Differential

regulation of tissue thiol-disulfide redox status in a murine model of peritonitis, submitted.

100. Tisherman SA, Kaplan L, Gracias V, Coopersmith CM, Beilman G, Toevs C, Byrnes MC. Providing

care for critically ill surgical patients: challenges and recommendations, submitted.

Book Chapters

1. Coopersmith CM, Moley JF. (1996) The Spleen. In: The Washington Manual of Surgery (D.

Baumann, L. Creswell, G. Doherty, J. Goss, T. Lairmore, editors), Little, Brown and

Company, pp. 280-286..

2. Coopersmith CM, Kodner IJ. (1999) Colon, rectum, and anus. In: The Washington Manual of

Surgery (G. Doherty, J. Meko, J. Olson, G. Peplinski, N. Worrall, editors), Little, Brown and

Company, pp. 236-258..

3. Stromberg PE, Coopersmith CM. (2003) Proliferation of the gastrointestinal epithelium. In

Encyclopedia of Gastroenterology (L. Johnson, editor), Elsevier, pp. 725-730..

4. Coopersmith CM, Buchman TG. (2004) Perioperative care and monitoring of the surgical patient. In

Current Surgical Therapy (J. Cameron, editor), Mosby pp. 1105-1111..

5. Coopersmith CM, Kollef MH. (2004) Post-operative and ventilator-associated pneumonia. In ACS

Surgery Online (WW Souba, MP Fink, GJ Jurkovich et al editors). Chapter 18. WebMed Inc, New York.

http://www.acssurgery/.September 2004.

6. Husain KD, Coopersmith CM. (2005) Acute renal failure. In Complications in General Surgery (G.

Doherty, M. Mulholland, editors). Lippincott Wilkins and Williams, pp. 150-156.

7. Chung P, Coopersmith CM. (2005) Critical Care. In: The Washington Manual of Surgery (K. Amos,

D. Green, S. Hunt, V. Halpin, M. Klingensmith, editors), Little, Brown and Company. pp. 177-196

8. Coopersmith CM, Babcock HM, Zack JE, Cobb JP. Infection control in the intensive care unit. In:

Surgical Infections (D. Fry, editor). Little, Brown and Company, Boston, In press.

9. Coopersmith CM, Kollef MH. (2005) 18 Post-operative and ventilator-associated pneumonia. 7 Critical

Care. In ACS Surgery Online (WW Souba, MP Fink, GJ Jurkovich et al editors). WebMed Inc, New York.

http://www.acssurgery/.August 2005 (update of chapter #5)

10. Coopersmith CM. (2006) Molecular foundations of cellular injury: Apoptosis and necrosis. In

Pediatric Critical Care (B. Fuhrman and J. Zimmerman, editors). Mosby, pp. 1444-1452.

11. Coopersmith CM, Buchman TG. (2007) Perioperative management of the emergency surgery

patient: the ICU and the intensivist. In Acute Care Surgery Principles and Practice (L. Britt, D. Trunkey, D.

Feliciano, editors). Springer, pp. 67-83.

12. McConnell KW, Kirby J, Coopersmith CM. (2007) Cellulitis/Fasciitis/Myositis. In The Washington

Manual of Critical Care (M. Kollef, editor), Lippincott, Williams and Wilkins, pp. 266-270.

13. Fox A, Coopersmith CM. (2008) Hemostasis and transfusion. In: The Washington Manual of

Surgery (L Chen, S Glasgow, T Goers, S Melby and M. Klingensmith, editors), Lippincott, Williams and

Wilkins, pp. 92-107.

14. Rivet E, Coopersmith CM. (2008) Surgical critical care. In: The Washington Manual of Surgery (L

Chen, S Glasgow, T Goers, S Melby and M. Klingensmith, editors), Lippincott, Williams and Wilkins,

(update of chapter #7) , pp. 134-152, Philadelphia, PA.

15. Efron PA, Coopersmith CM. (2009) Sepsis. In: Trauma, Surgical Critical Care, and Surgical

Emergencies (R. Rabinovici, H. Frankel, O. Kirton, editors), Informa, in press.

16. Nix SA , Coopersmith CM (2009) Selective Decontamination of the Digestive Tract. In Evidence-

Based Practice of Critical Care (C. Deutschman, P. Nelligan, editors), in press.

17. Southard RE, Coopersmith CM. (2010) Acute renal failure. In Complications in General Surgery (G.

Doherty, M. Mulholland, editors). Lippincott Wilkins and Williams, in press.

18. Muenzer JT, Coopersmith CM. (2010) Molecular foundations of cellular injury: Apoptosis, necrosis,

and autophagy. In Pediatric Critical Care (B. Fuhrman and J. Zimmerman, editors). Mosby, pp. 1444-

1452.

19. Dominguez JA, Coopersmith CM (2010) Gut dysfunction. In Encyclopedia of Intensive Care

Medicine (JL Vincent and J Hall, editors), Spinger, in press.

20. Coopersmith CM, Kollef MH. (2012) Post-operative and ventilator-associated pneumonia. Critical

Care. In ACS Surgery Online (WW Souba, MP Fink, GJ Jurkovich et al editors). WebMed Inc, New York.

http://www.acssurgery/.August 2011 (update of chapter #9)

21. Lamm RL, Coopersmith CM (2012) Hypovolemic and Hemorrhagic Shock. In Comprehensive Critical

Care Review Book (Roberts, Todd, et al. editors) Society of Critical Care Medicine, pp. 183-198..

22. McConnell KW, Coopersmith CM (2012) Common cardiac arrythmias. In SCORE, General Surgery

Resident Curriculum https://portal.surgicalcore.org/, in press. Invited Presentations: 1. Apoptotic Mechanisms in Shock and Sepsis? Twenty fourth Annual Conference on Shock, Shock

Society. Marco Island, FL. June 10, 2001.

2. Intestinal apoptosis in shock and sepsis. IBD Research: Junior Faculty Symposium, Northwestern

University, January 12, 2002

3. Prevention of nosocomial gram-positive infections: Daybreak session "New strategies for the

prevention and treatment of gram-positive infections in the ICU," 31st Critical Care Congress, Society of

Critical Care Medicine, Jan 29, 2002

4. Effect of education programs in preventing nosocomial infections. Department of Medicine Grand

Rounds, University of Nebraska, May 24, 2002.

5. Intestinal epithelial apoptosis. 33rd Critical Care Congress, Society of Critical Care Medicine, Orlando,

FL, Feb. 22, 2004.

6. Gut epithelial apoptosis and injury. 6th World Congress on Trauma, Shock, Inflammation and Sepsis -

Pathophysiology, Immune Consequences and Therapy, Munich, Germany March 2-6, 2004.

7. Sepsis induced apoptosis in the gastrointestinal tract. 6th World Congress on Trauma, Shock,

Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy, Munich, Germany

March 2-6, 2004.

8. Epithelial response to critical illness and stress. 6th World Congress on Trauma, Shock, Inflammation

and Sepsis - Pathophysiology, Immune Consequences and Therapy, Munich, Germany March 2-6, 2004.

9. Role of education in preventing bacteremia. 24th International Symposium on Intensive Care and

Emergency Medicine, Brussels, Belgium, March 30-April 2, 2004.

10. Hypophosphatemia. 24th International Symposium on Intensive Care and Emergency Medicine,

Brussels, Belgium, March 30-April 2, 2004.

11. Manipulating apoptosis. 24th International Symposium on Intensive Care and Emergency Medicine,

Brussels, Belgium, March 30-April 2, 2004.

12. Preventing infections in the critically ill surgical patient. Illinois Surgical Society, Rend Lake, IL, Sept

11, 2004.

13. Good and bad cell death (apoptosis in sepsis). 34th Critical Care Congress, Society of Critical Care

Medicine, Phoenix, AZ, Jan 15, 2005

14. Gut epithelial apoptosis in critical illness. 34th Critical Care Congress, Society of Critical Care

Medicine, Phoenix, AZ, January 16, 2005

15. The role of education in preventing primary bacteremia. 34th Critical Care Congress, Society of

Critical Care Medicine, Phoenix, AZ, January 17, 2005

16. Barrier failure in sepsis: when normal cell death processes go awry. Twenth eighth annual

conference on Shock, Shock Society, Marco Island, FL, June 4-7, 2005.

17. Gut epithelial apoptosis and sepsis. Surgical Biology Club II, San Francisco, CA October 15, 2005.

18. Prevention of Catheter-releated bacteremia in the surgical intensive care unit. 162nd meeting, Society

of Clinical Surgery, St. Louis, MO, November 4, 2005.

19. Evidenced medicine and protocol usage in the surgical intensive care unit. Department of Surgery

grand rounds. Loma Linda University, November 30, 2005.

20. Antimicrobial impregnated catheters in low infection rates. 35th Critical Care Congress, Society of

Critical Care Medicine, San Francisco, CA, January 23, 2006.

21. Gut epithelium/bacteria – it is the cause of all inflammation? 35th Critical Care Congress, Society of

Critical Care Medicine, San Francisco, CA, January 23, 2006.

22 .The gut as the motor of the systemic inflammatory response syndrome. 35th Critical Care Congress,

Society of Critical Care Medicine, San Francisco, CA, January 25, 2006.

23. The gut in sepsis – a tale of apoptosis, crosstalk and aging. Basic Science Seminar. Department of

Surgery and The Burn and Shock Trauma Institute at Loyola University Medical Center, March 22, 2006.

24. All patients with refractory septic shock should get low dose steroid therapy (pro in pro/con debate).

25th annual meeting of the Surgical Infection Society, San Diego, CA April 29, 2006.

25. Gut apoptosis in sepsis. Ohio State University Critical Care Center. June 23, 2006.

26. Cost of infections and cost-effectiveness of infection control. The 46th Interscience Conference on

Antimicrobial Agents and Chemotherapy (ICAAC) San Francisco, CA September 27-30, 2006.

27. Prevention of catheter-related bloodstream infections. 92nd annual clinical congress of the American

College of Surgeons. Chicago, IL, October 10, 2006.

28. Experience with tight glucose control in the Surgical Intensive Care Unit. 92nd annual clinical

congress of the American College of Surgeons. Chicago, IL, October 11, 2006.

29. The use of anti-apoptotic agents following injury. American Heart Association Resuscitative Science

Symposium. Chicago, IL November 10, 2006.

30. Interactions between the gut epithelium and the adaptive immune system in sepsis. 36th Critical Care

Congress, Society of Critical Care Medicine, Orlando, FL, February 19, 2007.

31. The promise of apoptosis inhibition and barriers to therapeutic implementation. 7th World Congress

on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy,

Munich, Germany March 14. 2007.

32. Is it possible to preserve and protect the mucosa in critical illness? 7th World Congress on Trauma,

Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy, Munich,

Germany March 14. 2007.

33. Prevention of catheter-related bloodstream infections. American Association of Surgical Physician

Assistants, New Orleans, LA Oct. 6, 2007.

34 Intestinal apoptosis and the pathophysiology/treatment of sepsis. Department of Surgery grand

rounds. Medical College of Georgia, November 26, 2007. Also evening conference Infection Control in

the ICU.

35. NIH – Basic Science Research Funding. 21st Annual Congress Eastern Association for the Surgery of

Trauma, Amelia Island Plantation, FL January 15, 2008.

36. Pseudomonas aeruginosa and Streptococcus pneumoniae and the host inflammatory response. 37th

Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008.

37. Aging and the host response to sepsis. 37th Critical Care Congress, Society of Critical Care

Medicine, Honolulu, HI February 1-6, 2008.

38. Funding At Mid-career: Getting Past The K Award. 37th Critical Care Congress, Society of Critical

Care Medicine, Honolulu, HI February 1-6, 2008.

39. Catheter-related bloodstream infection. Association of Perioperative Registered Nurses – Puerto Rico

Chapter, San Juan, PR, Feb 22, 2008.

40. Cathter-related bloodstream infection. Integrating pulmonary and critical care medicine into clinical

practice. Creighton University, Omaha, NE April 4, 2008.

41. Trauma patients. Integrating pulmonary and critical care medicine into clinical practice. Creighton

University, Omaha, NE April 4, 2008.

42. EGF in Sepsis: Finally a Molecule to Protect the Injured Gut? 38th Critical Care Congress, Society of

Critical Care Medicine, Nashville, TN January 30-February 4, 2009.

43. Gut Epithelial Apoptosis and Sepsis Chiba University Medical School, Chiba University, Chiba Japan,

November 2, 2009.

44. EGF in Sepsis: A Molecule to Protect the Injured Gut? And Infection Control and Patient Safety in the

ICU. Juntendo University and Tokyo Medical School, Tokyo, Japan, November 4, 2009.

45. EGF in Sepsis: A Molecule to Protect the Injured Gut? And Infection Control and Patient Safety in the

ICU. Osaka University Medical School, Osaka, Japan, November 7, 2009.

46. Motivating 80 Hour Residents to be 100 Hour Attendings. 39th Critical Care Congress, Society of

Critical Care Medicine, Miami, FL February, 2010.

47. The roles of lymphocytes and apoptosis in the modulation of intestinal inflammation. 8th World

Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and

Therapy, Munich, Germany March 9-13, 2010.

48. Death of gastrointestinal epithelial cells in sepsis and trauma. 8th World Congress on Trauma, Shock,

Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy, Munich, Germany

March 9-13, 2010.

49. Gut Epithelial Apoptosis and Sepsis. Also second talk: The Gut in Sepsis: Concepts, Opportunities,

Challenges, University of Chicago, August 4-5, 2010.

50. Aging and the host response to sepsis. Also second talk: Gut epithelial integrity in sepsis, University

of Pennsylvania, December 1-2, 2010

51. Role of Cell Death, 40th Critical Care Congress, Society of Critical Care Medicine, San Diego, CA

January 16, 2011.

52. The gut: can we protect the gut in critical illness. 41st Critical Care Congress, Society of Critical Care

Medicine, Houston, TX , Feb 4-8, 2012.

53. A comparison of critical care research funding and the financial burden of critical illness in the United

States. 41st Critical Care Congress, Society of Critical Care Medicine, Houston, TX , Feb 4-8, 2012.

54. Infection control. Surgical Critical Care Board Review at the 98th Annual Clinical Congress of the

American College of Surgeons, Chicago, IL September 30, 2012.

Scientific Presentations

1. Coopersmith CM, Chandrasekaran C, Gordon JI. Studies in transgenic mice reveal that

p53 is required for SV40 T Antigen and human K-rasVal12 to cooperate to produce dysplasia in villus-

associated intestinal enterocytes. Presented to the American College of Surgeons 81st Annual

Clinical Congress, New Orleans, LA, October 24, 1995.

2. Coopersmith CM, Chandrasekaran C, Gordon JI. K-rasVal12 causes a p53-independent increase in

apoptosis in proliferating villus-associated enterocytes in transgenic mice. Presented to the American

Association for Cancer Research Special Conference on Cancer Susceptibility Genes and Molecular

Carcinogenesis. Keystone, CO, February 23, 1996.

3. Coopersmith CM, Chandrasekaran C, Gordon JI. Radiation-induced apoptosis in the small

intestine of transgenic mice: additional evidence for cell nonautonomous regulation. Presented to the

American Society for Clinical Investigation in conjunction with Science Magazine Biomedicine ‘96 Medical

Research from Bench to Bedside. Washington, D.C., May 6, 1996.

4. Coopersmith CM, Brennan DC, Miller B, Shenoy S, Ramachandran V, Mohanakumar T, Ceriotti CS,

Howard TK, Lowell JA. Renal transplantation following previous solid organ transplantation: an 8-year

single-center experience. Presented to Transplant 2000, Joint meeting of American Society of

Transplantation and American Society of Transplant Surgeons. Chicago, IL, May 16, 2000. Also

presented at St. Louis Surgical Society. St. Louis, MO, January 17, 2000.

5. Wizorek JJ, Cobb JP, Qui Y, Laramie J, Coopersmith CM, Hotchkiss RS, Karl I.E, Buchman TG. Heat

shock paradox: subsequent heat shock increases lethality of polymicrobial sepsis in vivo. Presented to

21st International Symposium on Intensive Care and Emergency Medicine, Brussels, March 20-23, 2001.

6. Tinsley K, Swanson P, Coopersmith C, Wagner T, Schmieg R, Chang K, Osborne D, Freeman B,

Cobb J, Buchman T, Karl I, Hotchkiss R. Sepsis causes loss of CD3 T cells, B cells, and lymphoid

follicles. Presented to the Twenty fourth Annual Conference on Shock, Shock Society. Marco Island, FL.

June 9-12, 2001.

7. Coopersmith CM, Stromberg PE, Dunne WM, Davis CG, Buchman TG, Hotchkiss RS.

Overexpression of Bcl-2 in the intestinal epithelium improves survival in a model of pseudomonas

pneumonia-induced sepsis. Presented to the 31st Critical Care Congress, Society of Critical Care

Medicine, San Diego CA, Jan 26-30, 2002.

8. Taylor B, Huey W, Coopersmith C, Buchman T. Clinical effectiveness of a phosphorus repletion

protocol in a surgical intensive care unit. Presented to the 31st Critical Care Congress, Society of Critical

Care Medicine, San Diego CA, Jan 26-30, 2002.

9. Coopersmith CM, Stromberg PE, Davis CG, Dunne WM, Amiot DM, Karl IE, Hotchkiss RS, Buchman

TG. Sepsis from Pseudomonas aeruginosa pneumonia induces gut epithelial cell cycle arrest. Presented

to the 25th Annual Conference on Shock, Shock Society, Big Sky, Montana June 9, 2002.

10. Husain KD, Stromberg PE, Dunne WM, Turnbull IR, Hotchkiss RS, Karl IE, Buchman TG, Coopersmith CM, Acute lung injury causes increased gut epithelial apoptosis and decreased

proliferation in mice. Presented to the 32nd Critical Care Congress, Society of Critical Care Medicine,San

Antonio, TX, Jan 28 - Feb 2, 2003.

11. Javadi P, Turnbull IR, Coopersmith CM, Hotchkiss RS, Buchman TG. Aging is associated with

increased IL-6 and splenic apoptosis following cecal ligation and puncture. Presented to the 32nd Critical

Care Congress, Society of Critical Care Medicine,San Antonio, TX, Jan 28 - Feb 2, 2003.

12. Taylor BE, Huey W, Buchman TG, Boyle WA, Coopersmith CM. Clinical Effectiveness of a nurse

driven insulin infusion protocol in the surgical ICU. Presented to the 32nd Critical Care Congress, Society

of Critical Care Medicine,San Antonio, TX, Jan 28 - Feb 2, 2003. (Research citation award winner).

13. Husain KD, Amiot DM, Stromberg PE, Davis CG, Dunne WM, Buchman TG, Karl IE, Hotchkiss RS,

Coopersmith CM. Streptococcus Pneumoniae infection in mice: apoptosis and survival. Presented to the

23rd Annual Meeting, Surgical Infection Society, San Antonio. TX, April 10-12, 2003.

14. Coopersmith CM, Zack JE, Ward MR, Schallom ME, Sona CS, Huey WY, Buchman TG, Boyle WA,

Fraser VJ, Polish LB. Education alters behavior and impacts catheter-related bloodstream infection rates

in the surgical ICU. Presented to the 23rd Annual Meeting, Surgical Infection Society, San Antonio. TX,

April 10-12, 2003 (finalist for best abstract competition).

15. Turnbull IR, Javadi P, Coopersmith CM, Hotchkiss RS, Buchman TG. IL-6 predicts septic mortality in

ND4 mice and antibiotics fail to rescue septic mice with high IL-6. Presented to the 23rd Annual Meeting,

Surgical Infection Society, San Antonio. TX, April 10-12, 2003.

16. Schallom ME, Coopersmith CM, Sona CS, Huey WY, Taylor BT. Keepting rotating residents in the

loop. Presented to the National Teaching Institute for the American Association of Critical Care Nurses,

San Antonio, TX, May 17-22, 2003.

17. Husain KD, Stromberg PE, Javadi P, Amio DM, Buchman TG, Karl IS, Hotchkiss, Coopersmith CM.

Bcl-2 inhibits gut epithelial apoptosis but does not improve survival in acute lung injury. Presented to the

26th Annual Conference on Shock, Shock Society, Phoenix, AZ June 7-10, 2003 (young investigator

award finalist).

18. Stromberg PE, Turnbull IR, Chang KC, Husain KD, Hotchkiss, RS, Buchman TG, Coopersmith CM.

Lymphocytes alter gut epithelial proliferation but not apoptosis in sepsis. Presented to the 26th Annual

Conference on Shock, Shock Society, Phoenix, AZ June 7-10, 2003.

19. Husain KD, Stromberg PE, Woolsey CA, Hotchkiss WR, Buchman TG, Hotchkiss RS, Karl IE,

Coopersmith CM. Altered gut epithelial apoptosis and proliferation in acute lung injury: the roles of Bcl-2,

TLR4, and TNF-alpha. Presented to the 33rd Critical Care Congress, Society of Critical Care Medicine,

Orlando, FL , Feb 22-25, 2004.

20. Husain KD, Stromberg PE, Woolsey CA, Turnbull IR, Buchman TG, Karl IE, Hotchkiss RS,

Coopersmith CM. Lung injury uncouples gut apoptosis and proliferation. Presented to the 6th World

Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and

Therapy, Munich, Germany March 2-6, 2004.

21. Javadi P, Stromberg PE, Husain KD, Woolsey CA, Buchman TG, Karl IE, Hotchkiss RS,

Coopersmith CM. Exogenous iron after sepsis increases mortality and alters apoptosis. Presented to the

6th World Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune

Consequences and Therapy, Munich, Germany March 2-6, 2004. 22. Stromberg PE, Chang KC, Woolsey CA, Hotchkiss WR, Buchman TG, Karl IE, Hotchkiss RS,

Coopersmith CM. Gut overexpression of Bcl-2 requires lymphocytes to improve survival. Presented to

the 6th World Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune

Consequences and Therapy, Munich, Germany March 2-6, 2004.

23. Warren DK, Jones RM, Coopersmith CM, Seiler SM, Merz LR, Zack JE, Ward MR, Fraser VJ. The

Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Surgical Intensive Care Unit.

Presented to the 14th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America,

Philadelphia, PA, April 17-20, 2004.

24. Woolsey CA, Stromberg PE, Javad P, Husain KD, Chang KC, Hotchkiss RS, Karl IE, Buchman TG,

Coopersmith CM. The adaptive immune system mediates gut epithelial apoptosis following cecal

ligationa and puncture. Presented to the 27th Annual Conference on Shock, Shock Society, Halifax,

Canada June 5-8, 2004 (travel awardee).

25. Stromberg PE, Woolsey CA, Husain KD, Dunne WM, Buchman TG, Karl IE, Hotchkiss RS,

Coopersmith CM, Mice expressing caspase-3 resistant retinoblastoma protein have decreased gut

epithelial but not splenic apoptosis in Pseudomonas aeruginosa pneumonia. Presented to the 27th

Annual Conference on Shock, Shock Society, Halifax, Canada June 5-8, 2004 (travel awardee).

26. Husain KD, Stromberg PE, Woolsey CA, Dunne WM, Buchman TG, Karl IE, Hotchkiss RS,

Coopersmith CM, Gut epithelial apoptosis occurs via the mitochondrial and receptor-mediated pathways

in Streptococcus pneumoniae pneumonia. Presented to the 27th Annual Conference on Shock, Shock

Society, Halifax, Canada June 5-8, 2004 (travel awardee).

27. Javadi P, Buchman TG, Turnbull IR, Stromberg PE, Coopersmith CM. Gut epithelial and splenic

apoptosis in septic Hfe-/- mice are age dependent. Presented to the 27th Annual Conference on Shock,

Shock Society, Halifax, Canada June 5-8, 2004.

28. Warren DK, Jones RM. Coopersmith CM, Seiler SM, Merz LR, Zack JE, Ward MR, Fraser VJ.

The Impact of an Active Surveillance Program on MRSA Detection and Contact Precaution Utilization in a

Surgical Intensive Care Unit. Presented to the 42nd Annual Meeting of the Infectious Diseases Society of

America, Boston, MA, September 30 - October 3, 2004

29. McDunn JE, Husain KD, Coopersmith CM, Townsend RR, Cobb JP. Comparison of the plasma

proteome during Gram-positive and Gram-negative pneumonia in mice. Presented to the American

College of Surgeons 81st Annual Clinical Congress, New Orleans, LA, October 10-14, 2004.

30. Buchman TG, Taylor BE, Coopersmith CM. The journey from literature evidence to clinical protocol.

Presented to the World Shock Forum, Tokyo, Japan, October 30, 2004. 31. Freeman BD, Kennedy CM, Coopersmith CM, Zehnbauer BA, Buchman TG. Perceptions and

attitudes of genetic research held by surrogate decision makers for critically ill patients. Presented to 2004

Office of Research Integrity Research Conference on Research Integrity, San Diego, CA, November 12-

14, 2004.

32. McConnell KW, DiPasco PJ, Turnbull IR, Dunne WM, Buchman TG, Hotchkiss RS, Karl IE,

Coopersmith CM. Pathobiological comparison of gram positive and gram negative murine pneumonia.

Presented to the 34th Critical Care Congress, Society of Critical Care Medicine, Phoenix, AZ, January 16-

19, 2005.

33. Woolsey CA, Dunne WM, Hotchkiss RS, Buchman TG, Karl IE, Coopersmith CM. The relationship

between gut epithelial apoptosis and proliferation in sepsis is dependent on mortality but independent on

type of infection. Presented to the 34th Critical Care Congress, Society of Critical Care Medicine,

Phoenix, AZ, January 16-19, 2005.

34. Taylor B, Huey W, Buchman T, Boyle W, Ward M, Schallom L, Sona C, Zack J, Thomas J, Mazuski J,

Kaiser K, Coopersmith C. Clinical effectiveness of a nurse driven insulin infusion protocol with a target

range of 80-100 mg/dl. Presented to the 34th Critical Care Congress, Society of Critical Care Medicine,

Phoenix, AZ, January 16-19, 2005.

35. Husain KD, Polpitya A, McDunn J, Tong A, MacMillan S, Coopersmith CM, Cobb JP. Untangling

pneumonia from inflammation: leukocyte microarray gene expression profiles can diagnose pneumonia

and distinguish between causative bacteria. Presented to the 34th Critical Care Congress, Society of

Critical Care Medicine, Phoenix, AZ, January 16-19, 2005 (Educational award winner).

36. DiPasco PJ, Chang KC, Davis CG, Unsinger J, Ferguson TA, Karl IE, Coopersmith CM, Hotchkiss

RS. CD40 Ligand protects against sepsis induced B-cell apoptosis. Presented to the 34th Critical Care

Congress, Society of Critical Care Medicine, Phoenix, AZ, January 16-19, 2005.

37. Vyas D, Javadi P, DiPasco PJ, Buchman TG, Hotchkiss RS, Karl IE, Coopersmith CM. Early

antibiotic therapy, but not anti-IL-6 antibody, rescue mice predicted to die by high IL- 6 levels in sepsis.

Presented to the 66th annual meeting of the Society of University Surgeons, Nashville, TN, February 10,

2005.

38. Adams SR, Warren DK, Jones RM, Coopersmith CM, Seiler SM, Merz LR, Zack JE, Ward MR,

Fraser VJ. The epidemiology of methicillin-sensitive and methicillin-resistant Staphylococcus aureus in a

surgical intensive care unit. Presented to the 15th annual meeting of the Society for Healthcare

Epidemiology of America, Los Angeles, CA, April 10, 2005.

39. Warren DK, Jones RM, Coopersmih CM, Merz LR, Zack JE, Fraser VJ. Contact Precaution

Utilization in a Surgical Intensive Care Unit. Presented to the 15th annual meeting of the Society for

Healthcare Epidemiology of America, Los Angeles, CA, April 10, 2005.

40. McConnell KW, DiPasco PJ, Turnbull IR, Dunne WM, Buchman TG, Hotchkiss RS, Karl IE,

Coopersmith CM. Pathobiological comparison of high and intermediate mortality Pseudomonas murine

pneumonia. Presented to the 25th annual meeting of the Surgical Infection Society, Miami, FL, May 5,

2005.

41. McConnell, KW, DiPasco P, Chang K, Schreiber T, Vyas D, Dunne WM, Buchman TG, Hotchkiss RS,

Coopersmith CM. Gram positive and gram negative murine pneumonia induce unique changes in

lymphocyte apoptosis and neutrophil migration. Presented to the 28th annual conference on Shock, Shock

Society, Marco Island, FL, June 4-7, 2005.

42. Brookmeyer PR, Jones R, Coopersmith CM, Fraser VJ, Schuerer DJE, Zack J, Warren DK.

Risk Factors associated with Catheter-associated Bloodstream Infections in a Surgical Intensive Care

Unit. Presented to the 43rd Annual Meeting of the Infectious Diseases Society of America, San Francisco,

CA, October 6-9, 2005.

43. Checchia PA, Polpitiya A, MacMillan S, Stromberg P, Coopersmith CM, Buchman TG, Cobb JP.

The Effect of Age on Myocardial Gene Expression Profiles in a Murine Model of Sepsis. Presented to the

35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, January 8-11, 2006.

44. Rajan S, Vyas D, Hotchkiss RS, Buchman TG, Coopersmith CM. Intestine Specific Overexpression

of IL-10 Improves Survival in a Polymicrobial Model of Sepsis. Presented to the 35th Critical Care

Congress, Society of Critical Care Medicine, San Francisco, January 8-11, 2006.

45. Woolsey CA, McConnell KW, Martin J, Boody B, Hotchkiss RS, Karl IE, Coopersmith CM. TLR4

Signaling Changes White Blood Cell Distribution in Pseudomona pneumonia. Presented to the 35th

Critical Care Congress, Society of Critical Care Medicine, San Francisco, January 8-11, 2006.

46. McConnell KW, Chang K, Wagner T, Coopersmith CM, Hotchkiss RS. Peptide transduction domain

delivery of anti-apoptotic proteins decreases E. coli induced apoptosis in human lymphocytes. Presented

to the 35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, January 8-11, 2006.

47. Robertson CM, Stromberg PE, Vyas D, Martin J, Sherman B, Hotchkiss RS Buchman TG,

Coopersmith CM. Identifying the optimal method to quantify gut apoptosis in critical illness. Presented to

the 35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, January 8-11, 2006.

48. Sona C, Zack J, Schallom L, Schwartkopf L, Huey W, McSweeney M, McMullen K, Mazuski J,

Schuerer D, Coopersmith C, Boyle W, Buchman T. A simple, low-cost oral care protocol reduces

ventilator-associated pneumonia rates. Presented to the 35th Critical Care Congress, Society of Critical

Care Medicine, San Francisco, January 8-11, 2006.

49. Wagner TH, McConnel KW, Chang KC, Dunne JC, Yuan KZ, Cobb JP, Karl IE, Coopersmith CM,

Hotchkiss RS. Gene expression analysis of E. coli induced apoptosis of human lymphocytes and the

protective effect of Tat-BH4. Presented to the 35th Critical Care Congress, Society of Critical Care

Medicine, San Francisco, January 8-11, 2006.

50. Schwulst SJ, Davis C, Chang K, Dunne WM, Serber D, Zhou TT, Coopersmith C, Karl I, Hotchkiss

R. Bim-/- mice have nearly complete protection against lymphocyte apoptosis and improved survival in

septic peritonitis. Presented to the 35th Critical Care Congress, Society of Critical Care Medicine, San

Francisco, January 8-11, 2006.

51. Merz LR, Guth RM, Woeltje KF, Camins BC, Kollef MH, Coopersmith CM, Fraser VJ. The cost of

vancomycin-resistant entorococci bloodstream infections in intensive care unit populations. Presented to

the 16th annual meeting of the Society of Healthcare Epidemiology of America, Chicago, IL, March 18-21,

2006.

52. Woeltje KF, Merz LR, Guth RM, Camins BC, Kollef MH, Coopersmith CM, Fraser VJ. Attributable

cost of antimicrobial resistance in gram-negative bacteremia. . Presented to the 16th annual meeting of

the Society of Healthcare Epidemiology of America, Chicago, IL, March 18-21, 2006.

53. Guth RM, Merz LR, Woeltje KF, Camins BC, Olsen MA, Georgantopoulos P, Coopersmith CM, Kollef

MH, Fraser VJ. The attributable cost of methicillin-resistant Staphylococcus aureus bloodstream

infections. Presented to the 16th annual meeting of the Society of Healthcare Epidemiology of America,

Chicago, IL, March 18-21, 2006.

54. McConnell KW, Chang KC, Coopersmith CM, Piwnica-Worms D, Hotchkiss RS. Peptide transduction

domain delivery of anti-apoptotic compounds decreases radiation-induced apoptosis in human

lymphocytes. Presented to the 26th annual meeting of the Surgical Infection Society, LaJolla CA, April 27-

29, 2006.

55. Clark AT, McConnell, KW, Hunt CR, Buchman TG, Hotchkiss RS, Coopersmith CM. HSP 70.1 and

HSP70.3 mediate survival following cecal ligation and puncture in aged male mice. Presented to the

29th annual conference on Shock, Shock Society, Broomfield, CO, June 3-6, 2006 (travel awardee).

56. Rajan S, Woolsey CA, Hotchkiss RS, Buchman TG, Coopersmith CM. An examination of

mechanisms underlying the survival benefit conferred by intestine-specfic overexpression of interleukin-

10. Presented to the 29th annual conference on Shock, Shock Society, Broomfield, CO, June 3-6, 2006.

57. Woolsey CA, Stromberg PE, Hotchkiss RS, Buchman TG, Coopersmith CM. Aged mice have altered

cytokine profiles and intestinal permeability following cecal ligation and puncture. Presented to the 29th

annual conference on Shock, Shock Society, Broomfield, CO, June 3-6, 2006.

58. McConnell K, Dunne WM, Buchman TG, Hotchkiss RS, Coopersmith CM. Gram positive and gram

negative murine pneumonia induce unique local cytokine profiles. Presented to the 29th annual

conference on Shock, Shock Society, Broomfield, CO, June 3-6, 2006.

59. Turnbull I, Buchman T, Coopersmith CM. Modeling aging and sepsis. Presented to the 29th annual

conference on Shock, Shock Society, Broomfield, CO, June 3-6, 2006.

60. Piel DA, Gruber PJ, Weinheimer CJ, Courtois MR, Robertson CM, Coopersmith CM, Deutschman,

Levy RJ. Mitochondrial resusciation with exogenous cytochrome C in the septic heart. Presented to the

29th annual conference on Shock, Shock Society, Broomfield, CO, June 3-6, 2006.

61. Robertson CM, Klingensmith ME, Coopersmith CM. Long-term outcomes of performing laboratory

research during surgical residency. Presented to the 92nd annual clinical congress of the American

College of Surgeons. Chicago, IL, October 11, 2006.

62. Robertson TE, Cracchilo L, Buckles M, Schallom L, Sona C, Fine S, Schuerer D, Coopersmith CM,

Buchman TG. Increase in extubation rate with implementation of daily spontaneous breathing trials.

Presented to the 36th Critical Care Congress, Society of Critical Care Medicine, Orlando, FL, February

17-21, 2007.

63. Robertson CM, Martin J, Boody B, Dunne WM, Hotchkiss R, BuchmanT, Coopersmith CM.

Neutrophil depletion allows creation of a virulent model of staphylococcus aureus pneumonia. Presented

to the 36th Critical Care Congress, Society of Critical Care Medicine, Orlando, FL, February 17-21, 2007.

64. McConnell KW, Muenzer JT, Chang KC, Coopersmith CM, Grigsby PW, Hotchkiss RS, Hunt CR.

Peptide transduction domain delivery of anti-apoptotic proteins decreases splenocyte apoptosis in pre-

and post-treatment models of murine radiation injury. Presented to the 36th Critical Care Congress,

Society of Critical Care Medicine, Orlando, FL, February 17-21, 2007 (Research Citation Finalist).

65. Clark JA, Hotchkiss RS, Buchman TG, Coopersmith CM. The role of epidermal growth factor in

sepsis. Presented to the 3rd annual Washington University School of Medicine Postdoct Scientific

Symposium. St. Louism MO March 1, 2007 (Best poster winner).

66. Clark AT, Woolsey CA, Dunne WM, Buchman TG, Hotchkiss RS, Coopersmith CM. Sepsis from

Pseudomonas aeruginosa pneumonia decreases intestinal epithelial proliferation and slows migration.

Presented to the 7th World Congress on Trauma, Shock, Inflammation and Sepsis - Interdisciplinary

Summit on Inflammation Munich, Germany March 13-17, 2007 (A.E. Baue Research Award as one of

top 5 abstracts).

67. Clark JA, Stromberg PE, Hotchkiss RS, Buchman TG, Coopersmith CM. Exogenous epidermal

growth factor improves intestinal integrity in sepsis. Presented to the 7th World Congress on Trauma,

Shock, Inflammation and Sepsis - Interdisciplinary Summit on Inflammation Munich, Germany March 13-

17, 2007.

68. Robertson CM, McConnell KW, Chang K, Houchen C, Hotchkiss RS, Coopersmith CM. Tat-BH4

Decreases Intestinal Epithelial Cell Death after Septic Insult in Vitro. Presented to the 7th World Congress

on Trauma, Shock, Inflammation and Sepsis - Interdisciplinary Summit on Inflammation Munich, Germany

March 13-17, 2007.

69. McConnell KW, McDunn JE, Turnbull IR, Dunne WM, Hotchkiss RS, Coopersmith CM. Gram

positive and gram negative bacteria initiate the host inflammatory response via different mechanisms.

Presented to the 7th World Congress on Trauma, Shock, Inflammation and Sepsis - Interdisciplinary

Summit on Inflammation Munich, Germany March 13-17, 2007.

70. Rogers TJ, Dunne WM, Guth RM, Merz LR, Coopersmith CM, Scheurer DJE, Fraser VJ, Warren DK.

Implications of a Chlorhexidine-based Washing Protocol on Methicillin-Resistant Staphylococcus aureus

Tolerance to Chlorhexidine Digluconate. Presented to the 17th Annual Scientific Meeting of the Society

for Healthcare Epidemiology of America, Baltimore, MD, April 14-17, 2007.

71. Clark JA, Hotchkiss RS, Buchman TG, Coopersmith CM. Decreased mortality following epidermal

growth factor treatment is associated with improved gut inegrity in sepsis. Presented to the 30th annual

conference on Shock, Shock Society, Baltimore, MD, June 9-12, 2007. (Young investigator award

finalist)

72. Clark AT, Turnbull IR, Stromberg PE, Woolsey CA, Buchman TG, Hotchkiss RS, Coopersmith CM.

Aging modulates local but not systemic inflammation following cecal ligation and puncture in mice.

Presented to the 30th annual conference on Shock, Shock Society, Baltimore, MD, June 9-12, 2007.

73. McConnell KW, Stromberg PE, Woolsey CA, Clark AT, Clark JA, Hotchkiss RS, Buchman TG,

Coopersmith CM. The survival advantage conferred by prevention of gut epithelial apoptosis in sepsis

occurs through the mitochondrial pathway and is dependent upon the presence of the adaptive immune

system. Presented to the 30th annual conference on Shock, Shock Society, Baltimore, MD, June 9-12,

2007.

74. Peck-Palmer OM, McConnell K, Unsinger J, Chang K, McDunn JE, Coopersmith CM, Hotchkiss RS.

Monocyte/macrophage apoptosis occurs with radiation and serum-deprivation but not E. coli. Presented

to the 30th annual conference on Shock, Shock Society, Baltimore, MD, June 9-12, 2007.

75. Robertson CM, McConnell KW, Martin J, Boody B, Diavolo J, Dunne WM, Coopersmith CM.

Neutrophil depletion inhibits pulmonary clearance of Staphylococcus aureus in mice. Presented to the

30th annual conference on Shock, Shock Society, Baltimore, MD, June 9-12, 2007.

76. Clark JA, Samocha A, Hotchkiss RS, Buchman TG, Coopersmith CM. NF-kB activation in

enterocytes reduces sepsis-induced gut inury. Presented to 37th Critical Care Congress, Society of

Critical Care Medicine, Honolulu, HI February 1-6, 2008.

77. Perrone EE, Clark JA, Hotchkiss RS, Buchman TG, Coopersmith CM. Loss of EGF receptor activity

leads to increased intestinal apoptosis and decreased villus height in sepsis. Presented to 37th Critical

Care Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008.

78. Robertson CM, Belt BA, Linehan DC, Buchman TG, Hotchkiss RS, Coopersmith CM. Novel models

of murine sepsis with comorbid pancreatic cancer. Presented to 37th Critical Care Congress, Society of

Critical Care Medicine, Honolulu, HI February 1-6, 2008.

79. Clark AT, Turnbull IR, Stromberg PE, Woolsey CA, Buchman TG, Hotchkiss RS, Coopersmith CM.

Age increases local but not systemic inflammation in murine sepsis. Presented to 37th Critical Care

Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008.

80. Fox AC, Clark AT, Zee-Cheng B, Dunne WM, Buchman TG, Hotchkiss RS, Coopersmith CM. Sepsis

from Pseudomonas aeruginosa pnemonia decreases epithelial proliferation and migration with partial

recovery of regenerative capacity 48 hours post-inury. Presented to 37th Critical Care Congress, Society

of Critical Care Medicine, Honolulu, HI February 1-6, 2008.

81. Taylor BE, Byrnes M, Schallom M, Sona C, Quist M, Boyle WA, Buchman TG, Coopersmith CM,

Tobin G. Implementation of a transition insulin protocol to maintain glycemic control after intensive insulin

therapy. Presented to 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI

February 1-6, 2008.

82. Gnerlich J, Coopersmith CM, Fraser V, Schuerer DJE. Increasing patient safety in a SICU: staff

concerns survey. Presented to 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu,

HI February 1-6, 2008.

83. Byrnes ME, Sona CS, Schuerer DJE, Mazuski JE, McKenzie W, Taylor BE, Boyle WA, Coopersmith

CM. Daily review of a checklist of ICU guidelines improves adherence to established ICU protocols and

objectives. Presented to 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI

February 1-6, 2008.

84. Robertson CM, Klingensmith ME, Coopersmith CM. National prevalence of full-time research

experience among general surgery residents. Presented to Third Annual Academic Surgery Congress,

Society of University Surgeons, Hungtington Beach, CA Feb 12-15, 2008.

85. Clark JA, Lawrance CP, Dunne WM, Coopersmith CM. Epidermal growth factor preserves intestinal

integrity and decreases mortality in a murine model of Pseudomonas aeruginosa pneumonia. Presented

to Experimenal Biology, San Diego, CA, April 5-9, 2008.

86. Perrone EE, Brahmamdan P, Davis CG, McDonough JS, Buchman TG, Hotchkiss RS, Coopersmith

CM. Radiation injury increases systemic infection and mortality in murine MRSA pneumonia. Presented to

to the 31st annual conference on Shock, Shock Society, Cologne, GE, June 28-July 2, 2008.

87. Clark AT, McConnell KW, Dunne WM, Dixon DJ, Cobb JP, Buchman TG, Hotchkiss RS,

Coopersmith CM. Anti-TNF modulates mortality from S. pneumoniae and P. aeruginosa pneumonia in

mice. Presented to to the 31st annual conference on Shock, Shock Society, Cologne, GE, June 28-July 2,

2008.

88. Fox A, Robertson C, Belt B, Dunne WM, Linehan D, Buchman T, Hotchkiss R, Coopersmith CM.

Sepsis from Pseudomonas aeruginosa pnemonia superimposed on pancreatic cancer increases gut

epithelial apoptosis, bacteremia, and mortality. Presented to to the 31st annual conference on Shock,

Shock Society, Cologne, GE, June 28-July 2, 2008. (Travel awardee).

89. Clark JA, Hotchkiss Rs, Buchman TG, Coopersmith CM. Intestinal overexpression of epidermal

growth factor inhibits gut epithelial apoptosis and improves mortality in sepsis. Presented to the 31st

annual conference on Shock, Shock Society, Cologne, GE, June 28-July 2, 2008.

90. Perrone EE, Clark JA, Clark AT, Dunne WM, Warner BW, Coopersmith CM. Staphylococcus aureus

induces intestinal injury in a murine model of pneumonia. Presented to the 2008 AAP National

Conference and Exhibition, Section on Surgery, Boston, MA, October 10-14, 2008.

91. Brahmamdam P, Chang KC, Zeida RK, Rele SM, Liang Y, Liu JY, Heidel JD, McDunn JE,

Coopersmith CM, Hotchkiss RS. siRNA targeted at pro-apoptotic proteins, PUMA and BIM, inhibits

sepsis-induced lymphocyte apoptosis. Presented to the 94th annual clinical congress of the American

College of Surgeons. San Francisco, CA October 12-16, 2008.

92. Clark J, Samocha A, Gan H, Coopersmith CM. Enterocyte-specific overexpression of epidermal

growth factor preserves intestinal barrier function in sepsis. Presented to the 38th Critical Care Congress,

Society of Critical Care Medicine, Nashville, TN January 31-February 4, 2009.

93. Jung E, Perrone EE, Brahmandan P, Davis CG, McDonough JS, Clark JA, Clark AT, Fox AC, Dunne

WM, Buchman TG, Hotchkiss RS, Coopersmith CM. Intestional overexpression of Bcl-2 decrease gut

epithelial apoptosis and improves survival in mice subjected to whole body irradiation followed by MRSA

pneumonia. Presented to the 38th Critical Care Congress, Society of Critical Care Medicine, Nashville,

TN January 31-February 4, 2009.

94. Clark AT, Hotckiss WR, Zee-Cheng BR, Clark JA, Fox AC, McConnell KW, Dunne WM, Buchman TG,

Coopersmith CM. Site and source of infection mediate local and systemic host response in septic mice.

Presented to the 38th Critical Care Congress, Society of Critical Care Medicine, Nashville, TN January

31-February 4, 2009.

95. Fox AC, Clark AT, Chang K, Dunne WM, Linehan D, Coopersmith CM. Preventing apoptosis in

septic mice with cancer unexpectedly increases mortality. Presented to the 38th Critical Care Congress,

Society of Critical Care Medicine, Nashville, TN January 31-February 4, 2009.

96. Schuerer DJE, Buchman TG, Coopersmith CM. Catheter-related bloodstream infection rates in

minocycline/rifampin vs. chlorhexidine/silver sulfadiazine-impregnated central venous catheters -- results

of a 46 month study Presented to the 38th Critical Care Congress, Society of Critical Care Medicine,

Nashville, TN January 31-February 4, 2009.

97. Brahmamdam, Coopersmith CM, Chang KC, Osborne DF, McDunn JE, Hotchkiss RS. Blocking PD-

1 inhibits lymphocyte apoptosis during sepsis. Presented to the 38th Critical Care Congress, Society of

Critical Care Medicine, Nashville, TN January 31-February 4, 2009.

97. Fox AC, McConnell KW, Clark AT, Dunne WM, Buchman TG, Hotchkiss RS, Coopersmith CM.

Endogenous bacteria decreae mortality in sepsis but do not change intestinal epithelial apoptosis or

proliferation. Presented to the 4th Annual Academic Surgical Congress, Fort Myers FL, February 3-6,

2009.

98. Clark JA, Xie Y, Coopersmith CM, Davidson NO. Impaired intestinal lipid metabolism decreases

mortality and improves intestinal integrity in Pseudomonas aeruginosa pneumonia-induced sepsis.

Presented to Digestive Disease Weeks, Chicago, IL, June 3, 2009.

99. Clark A, Zee-Cheng B, Dunne WM, Buchman TG, Hotchkiss RS, Coopersmith CM. Sepsis

uncouples gut epithelial proliferation and death from migration and cell density in mice. Accepted for

presentation to the 32nd annual conference on Shock, Shock Society, San Antonio, TX, June 6-9, 2009.

100. Clark J, Samocha A, Coopersmith CM. Anti-TNF prevents gut barrier dysfunction in septic mice.

Accepted for presentation to the 32nd annual conference on Shock, Shock Society, San Antonio, TX, June

6-9, 2009.

101. Jung E, Perron E, Clark J, Clark A, Dunne W, Buchman T, Hotchkiss R, Coopersmith CM.

Mechanisms of MRSA pneumonia-induced gut epithelial apoptosis. Accepted for presentation to the 32nd

annual conference on Shock, Shock Society, San Antonio, TX, June 6-9, 2009 (Travel awardee).

102. Fox A, McConnell K, Clark A, Dunne W, Coopersmith CM. The endogenous bacteria mediate

sepsis-induced increases in gut epithelial apoptosis. Accepted for presentation to the 32nd annual

conference on Shock, Shock Society, San Antonio, TX, June 6-9, 2009 (Travel awardee).

103. Inoue S, Davis CG, Muenzer JT, Coopersmith CM, Hotchkiss RS. The development of a clinically

relevant two-hit model of sepsis: Streptoccocus pneumoniae followed by Pseudomonas pneumonia.

Presented to the 39th Critical Care Congress, Society of Critical Care Medicine, Miami, FL January

January 10-13, 2010.

104. Dominguez J, Vithayathil P, Lawrance C, Coopersmith CM. Epidermal growth factor attenuates gut

injury and decreases mortality in Pseudomonas aeruginosa pneumonia-induced sepsis. Presented to the

33rd annual conference on Shock, Shock Society, Portland, OR, June 11-15, 2010 (Plenary abstract,

travel awardee).

105. Jung E, Perrone E, Brahmamdan, McDonough J, Davis C, Dominguez J, Hotchkiss R, Coopersmith

CM. Mechanisms through which gut Bcl-2 overexpression improves survival in mice given irradiation

followed by MRSA pneumonia. Presented to the 33rd annual conference on Shock, Shock Society,

Portland, OR, June 11-15, 2010 (Travel awardee).

106. Ingram T, Kamat P, Coopersmith C, Vats A. Impact of family presence during rounds on physician

comfort and perception of teaching and efficiency. Presented to the 40th Critical Care Congress, Society

of Critical Care Medicine, San Diego, CA January 15-18, 2011 (Patient and Family Specialty Award).

107. Dominguez J, Khailova L, Vithayathil P, Lawrance C, Coopersmith C. Decreased mortality following

epidermal growth factor treatment is associated with attenuated intestinal injury in Pseudomonas

aeruginosa pneumonia. . Presented to the 40th Critical Care Congress, Society of Critical Care Medicine,

San Diego, CA January 15-18, 2011

108. Liang Z, Breed ER, Dominguez JA, Coopersmith CM. The role of epidermal growth factor in

mediating age-dependent mortality in sepsis. Presented to the 34th annual conference on Shock, Shock

Society, Norfolk, VA, June 11-14, 2011.

109. Liang Z, Breed ER, Buchman TG, Coopersmith CM. Heavy water (D2O) sensitized mice to cecal

ligation and puncture (CLP). Presented to the 34th annual conference on Shock, Shock Society, Norfolk,

VA, June 11-14, 2011.

110. Breed ER, Jung E, Liang Z, Perone EE, Dominguez JA, Dunne WM, Burd EM, Buchman TG,

Coopersmith CM. Methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa pneumonia

induce inestinal epithelial apoptosis via distinct mechanisms. Presented to the 34th annual conference on

Shock, Shock Society, Norfolk, VA, June 11-14, 2011.

111. Perrone EE, Jung E, Dominguez JA, Clark AT, Fox AC, Dunne WM, Hotchkiss RS, Coopersmith

CM. Cecal ligation and puncture followed by MRSA pneumonia increases mortality in mice and blunts

production of local and systemic cytokines. Presented to the 97th Annual Clinical Congress, American

College of Surgeons, San Francisco, CA, October 2011.

112. Carpenter D, Gregg S, Owens D, Buchman TG, Coopersmith CM. Documentation of Patient Care

Time by Nurse Practitioners and Physician Assistants in the Intensive Care Unit Accepted for

presentation to the 41st Critical Care Congress, Society of Critical Care Medicine, Houston, TX , Feb 4-8,

2012.

113. Still M, Cross L, Carpenter D, Coopersmith CM. The turn team: a novel strategy for reducing unit

acquired pressure ulcers in the ICU. Accepted for presentation to the 41st Critical Care Congress, Society

of Critical Care Medicine, Houston, TX , Feb 4-8, 2012.

114. Yoseph B, Breed E, Liang Z, Fox AC, McConnell K, O’Donnell D, Dunne WM, Coopersmith CM.

Commensal bacteria play a protective role in mediating mortality from pneumonia-induced sepsis.

Accepted for presentation to the 33rd annual meeting of the Surgical Infection Society. Dallas, TX April 18-

21, 2012.

115. Yoseph B, Breed E, Liang Z, Dominguez JA, McConnell, Coopersmith CM. Sepsis increses

intestinal permeability by altering the tight junction. Accepted for presention to the 35th annual conference

on Shock, Shock Society, Miami, FL, June 10-13, 2012. (Travel awardee).

116. Breed ER, Liang Z, Wagener ME, Yoseph B, Ferrer IR, Ford ML, Buchman TG, Coopersmith CM.

Heavy water mitigates survival in septic mice. Accepted for presention to the 35th annual conference on

Shock, Shock Society, Miami, FL, June 10-13, 2012.

117. Liang Z, Xie Y, Dominguez JA, Breed ER, Yoseph B, Davidson NO, Coopersmith CM. Intestine-

specific Mttp deletion increases mortality in an aged murine model of Pseudomonas aeruginosa

pneumonia. Accepted for presention to the 35th annual conference on Shock, Shock Society, Miami, FL,

June 10-13, 2012. (Travel awardee).

118. Jaffree LS, Liang Z, Breed E, Coopersmith CM. The protective effect of epdiermal growth factor

during sepsis depends on the adaptive immune system. Accepted for presention to the 35th annual

conference on Shock, Shock Society, Miami, FL, June 10-13, 2012. (Travel awardee).

Trainees (laboratory):

2000-2004 Paul Stromberg -- Accepted to Vanderbilt School of Medicine (started 8/04)

2002-2004 Keary Husain, MD – Assistant Professor of Surgery, Washington University School of

Medicine

2002-2004 Pardis Javadi – ENT resident, Albany Medical Center

2002-2006 Cheryl Woolsey, BS –Physicians Assistant, Washington University

2003,2007 Isaiah Turnbull, PhD – Received PhD at Washington University after Masters training,

Now an general surgery resident at the same institution

2003-2005 Dinesh Vyas, MBBS – Accepted to PGY2 preliminary general surgical position University

of Pittsburgh (started 8/05) then to PGY4 categorical general surgical position Case

Western Reserve, Now an assistant professor of surgery Michigan State University

2004-2007 Kevin McConnell, MD – Assistant Professor of Surgery, Emory University School of

Medicine, Recipient of NIH Loan Repayment Program Grant 2004-2007

2005-2007 Charles Robertson, MD – Assistant Professor of Anesthesiology, Washington University

School of Medicine

2005-2006 Saju Rajan – MA/MD student (obtained master’s degree following second year of medical

school at Washington University School of Medicine), now Radiation Oncology resident

Roswell Park Recipient of NIH NIDDK Medical Student Training Application 2005-

2006.

2005, 2006 James Martin (summer college student) – ENT resident, Loyola School of Medicine

2005, 2006 Barrett Boody (summer college student) – Accepted to University of Chicago School of

Medicine (started 9/08)

2005 Ben Sherman (summer college student) – Accepted to Arizona State for PhD program in

biochemistry (started 9/08)

2006 William Osberghaus (summer college student)

2006-2009 Jessica Clark, PhD – Assistant Professor of Anesthesiology, Colorado University.

Recipient of NIH National Research Service Award, Shock Society Young Investigator Award.

2007 Christopher Lawrance –General Surgery resident, Washington University School of

Medicine, Recipient of SIU Mentored Professional Enrichment Experience

Scholarship.

2007,8,9 Brendan Zee Chang (summer college student)

2007,8,9 Alexandr Samocha (outreach high school student) –University of Pennsylvania (started

9/08)

2007-2009 Amy Fox, MD -- Endocrine Surgery Fellow, University of Michigan

2007-2008 Erin Perrone, MD – Surgery Resident, Wayne State

2008-2009 Heng Gan (Washington University undergraduate student) – Accepted to Temple

University School of Medicine (starts 9/09) Recipient of Washington University

Department of Biology Summer Undegraduate Research Fellowship Award, also

graduated with honors thesis in biology from Washington University.

2008 Jada Roe – Medical student Washington University School of Medicine (summer after

first year of medical school). Recipient of NIH NIDDK Short-term Training Grant for

Medical Students.

2008-2009 Enjae Jung, MD – Vascular Surgery fellow, Washington University School of Medicine

2009 Paul Vithayathil (Washington University undergraduate student)

2010-present Elise Breed

2011-2012 Layla Jaffree (discover phase student, Emory University School of Medicine

2011-present Benyam Yoseph, MD – Postdoctoral fellow, Emory University School of Medicine

Trainees (clinical)

2002-2003 Aaron Sciifres – Assistant Professor of Surgery, St. Louis University

2002-2003 Joseph Rodriguez – Trauma Fellowship Cook County Hospital

2003-2004 Charles Hu – Assistant Professor of Surgery, Loma Linda University, SICU Director

Riverside County Regional Medical Center

2004-2005 Michael Edwards – Minimally invasive surgery fellowship, Harvard University, Assistant

Professor of Surgery Medical College of Georgia

2004-2005 Patricia Penkoske – Instructor, Washington University School of Medicine

2005-2006 Ellen Omi – Assistant Professor of Surgery, Loyola University

2005-2006 Pamela Peigh, private practice St. Louis, MO

2006-2007 Matthew Byrnes -- Assistant professor of surgery University of Minnesota

2007-2008 Matthew Goede –Assistant professor of surgery, University of Nebraska

2007-2008 Phil Efron – Assistant professor of surgery University of Florida

2008-2009 Robert Southard – Assistant professor of surgery, Washington University

2008-2009 Sean Nix—Assistant professor of surgery, University of Oklahoma

Mentees (other)

2008-2009 Chris Carpenter (Assistant Professor of Emergency Medicine, Washington University)

Recipient of Goldfarb Patient Safety Fellowship

Personal:

1983-present Songwriter/guitarist. Have written or co-written approximately 100 songs. Recently

recorded compact disc of original music. Have received college radio airplay,

commissioned to write and record themes for two cable television shows.

1983-1987 Editorial page editor, reporter The Daily Pennsylvanian. Over 250 publications including

multiple stories reported by the Associated Press. Named top college newspaper in

nation.

coopersmith cv april 2012 - pwr new · pdf fileawards & honors: 1987 phi beta kappa 1996...

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