1.Validity and Reliability ofMINI Arabic in Addiction Disorders . Albehairy A. MD, Sadek A MD, Ghanem M. MD, Asaad T. MD, Sheehan D.MD, Sheehan K PhDby Dr. Ahmed Albehairy, M.DPsychiatry Consultant Ministry of Health, Egypt

2. The Study Need& Hypothesis 3. Aim of The Work 4. Aim of The Work Primary:1- to examine the concordancebetween the MINI-Arabic and theCIDI Arabic, and between theSubstance use modules in bothMINI PLUS-Arabic & CIDI Arabic . 5. Aim of The Work ( cont.) Secondary :2- To compare the administration times of equivalent sections of the MINI-Arabic, MINI PLUS-Arabic, and CIDI- Arabic .3- To assess the concordance of MINI- Arabic and CIDI- Arabic comorbid diagnoses in patients with substance use disorders. 6. Aim of The Work ( cont.) Secondary ( cont.) :4- To assess the inter-rater and retest reliability of the MINI-Arabic.5- To assess the predictive value of screen items from the long form of the patient rated MINI-SCREEN in establishing rated MINI diagnoses. 7. SUBJECTS And METHOD 8. Subjects:1- Patient Group: A- Inclusion criteria. B- Exclusion criteria. C- Selection of cases.2- Control Group. 9. Method: 1- Procedure. 2- Tools applied in this work . 3- Statistical analysis. 10. Procedures of the WorkTRANSLATIONTRAINING PILOT STUDY CLINICAL HISTORYCLINICAL DIAGNOSISINFORMED CONSENT DEMOGRAPHIC INFORMATIONMINI-SCREEN RATED BY PATIENT MINI ADMINISTERED MINI ADMINISTERED& TIMEDBY 2ND RATER ON 20 PTS MINI PLUS MODULE ADMINISTERED & TIMED CIDI ADMINISTRERED & TIMED MINI READMINISTERED IN 1-2 DAYS TO 20 PATIENTS FOR RETESTDATA ENTRY DATA CHECKING/EDITING DATA ANALYSIS STATISTICAL REPORT FINAL THESIS WRITE UP 11. Tools Applied in This Work1- Mini International NeuropsychiatricInterview (MINI) 5.0, The MINI SCREEN( long form ) and MINI-PLUS 5.0.( sheehan etal., 1997)2- Composite International DiagnosticInterview (CIDI), Authorized core version1.0. ( WHO 1990 & Karam etal.,1993). 12. Statistical Analysis- Non parametric approach.- Validity and reliability of MINI & MINIPLUS modules ( by Kappa, PPV,NPV, Specificity, Sensitivity, &Efficiency ) .-Hot items analysis of MINI SCREEN( by Kappa, PPV, NPV, & Efficiency ) . 13. RESULTSRESULT 14. Demographic DataVariablePATIENTS DEPENDENCE AND ABUSE ControlX2 Chi- Sig (P) squareFREQ.%FREQ.%Age4.8 >0.0514-20 years 25 21.2%13 21.7%21-40 years 84 71.2%36 60%41-65 years 97.6% 11 18.3%Sex2.27>0.05Male11395.8%54 90%Female54.2% 610%Religion 0.399 >0.05Moslem10689.8%52 86.7%C. Orthodox 12 10.2%813.3%Marital Status 12.62 0.05Illiterate65.1% 41.7%1ry school86.8% 86.7%Preparatory 14 11.9%413.3%2ry 15 12.7%14 6.7% 15. Validity of MINICONCORDANC-+KappaSensitivity specificityNPV ppvEfficiencyE RATINGSTNFN FPTPCURRENT155 3 0.830.83 O.97O.970.83 O.96ALC.DEP. IN3 17MINI & CIDIDSM-III N= 178CURRENT153 3 0.730.82O.97O.98O.75O.94ALC.DEP. INMINI & CIDIICD-10 5 17LIFE TIME ALC. 938O.55O.86 O.73O.93O.57O.77DEP. IN MINI &CIDI DSM-III 3047LIFE TIME ALC. 898O.5 O.87 O.71O.92O.57O.76DEP. IN MINI &CIDI-ICD10 3447CURRENT713O.73O.96 O.83O.95O.86O.73DRUG DEP. INMINI & CIDI1490DSM-III 16. Validity of MINI ( CONT.)CONCORDANC - + KappaSensitivity specificityNPVppv EfficiencyE RATINGSTNFN FPTPLIFE TIME5511 0.71 0.9 0.790.83 0.830.86DRUGDEPENDENCE 1597IN MINI & CIDIICD-10CURRENT167 00.910.980.940.830.99DRUG ABUSEIN MINI & CIDI 2 9DSMIIICURRENT164 0 0.62 10.9710.630.95DRUG ABUSEIN MINI AND5 9CIDI ICD-10LIFE TIME16300.86 10.9810.750.98DRUG ABUSEIN MINI & CIDI 4 11DSMIILIFE TIME15900.76 1 0.96 10.640.96DRUG ABUSEIN MINI AND8 11CIDI ICD-10 17. Validity of MINI ( CONT.)CONCORDANC -+ Kappa Sensitivity specificityNPV ppvEfficiencyE RATINGSTN FN FP TPCOMORBID 99 1 0.840.97 O.88O.980.84 O.92DIAG IN MINI &CIDI DSMIII12 65COMORBID 1011 0.820.97O.88O.98O.81O.91DIAG IN MINI &CIDI ICD 1014 62ALC & DRUG 56 5O.87O.95 O.91O.91O.95O.94USE IN MINI &CLINICAL 5112IMPRESSIONCOMORBID 99 4O.77O.94 O.9 O.97O.79O.89DIAG IN MINI &CLINICAL 16 59IMPRESSION 18. RELIABILTY OF MINI Diagnoses ( n=118) Inter- rater Retest (Kappa) (Kappa)MINI 0.890.93MINI PLUS ( ALCOHOL &0.910.98DRUG CURRENT)MINI PLUS ( ALCOHOL & 0.940.89DRUG LIFE TIME )MINI PLUS ( COMORBID 0.85 0.84PSYCHIATRICDISORDERS) 19. Time duration of diagnostic interviews In MinutesMean S.D Median Min Max(in Min.) MINI 14.65 2.19 141122MINI Plus 18.94 3.73 181432 CIDI 45.08 6.09 422465MINI Plus Alcohol & Drug Module 12.29 2.2129 24CIDI Alcohol & Drug Module23.75 4.11 23.51856 MINI Control 7 0.4975 9 MINI Plus Control12.00 1.67 121015 CIDI Control24.6 3.16 242129 MINI Retest 14.6 2.57 131125 MINI Plus Retest 18.46 3.62 181529 20. Over all means of concordance of MINI SCREEN To MINI DiagnosesQuestions of MINI SCREENKappa NPVPPVEfficiencVersus MINI diagnoses yAll disorders questions 0.55 0.54 0.960.86 Drug dependence qs0.78 0.89 0.93 0.94Suicidal qs0.68 0.71 0.95 0.88 Major depression qs 0.70.73 0.90.86Antisocial personality qs0.67 0.70.96 0.87 Anxiety disorders qs0.49 0.41 0.99 0.89Somatization dis qs0.83 0.80.88 0.93 21. Hot items in MINI SCREEN of alcohol & drug use disordersDIAGNOSESRanked hot items related symptoms1- Alcohol use disorders 1- drink & drive . 2- black out . 3- have memory loss while drinking. 4-become abusive when drinking . 5- drink to intoxication ,feel guilty about drinking.2- Drug use disorders1-try to cut down ,try to control drug use. 2- have a problem because of your drug. Need more of drug to get high and are any one object to your drug use. 22. Hot items in MINI SCREEN ofComorbid Psychiatric disorders inalcohol & drug use disordersDIAGNOSESRanked hot items related symptoms1- Major depression1- depression2- Anxiety disorders 1- unexpected anxiety. 2- faintness. 3- sweaty palm. 4- unsteadiness. 5- diarrhea. 6- trembling.3-Antisocial personality 1- intimidate others. 2- threaten other. 3- bully with other 23. DISCUSSION & CONCLUSION1- MINI & precision of diagnosis inpsychiatry.2- Sample study.3- MINI, MINI PLUS: ( length of interview,validity, and reliability).4- MINI SCREEN .5- Conclusion. 24. IMPLICATIONS1- It is very beneficial to use MINI as a diagnostic screening tool for psychiatric hospital admission and out patient clinic evaluation.2- MINI can be used as a first step in outcome symptoms and disorders tracking, preparing for establishing data base in substance use disorders and management care service in Arab world.3. MINI Screen can be used in primary care service.