corporate presentation · 8 differentiated orthopedic imaging platform addressing weaknesses in...
TRANSCRIPT
CONNECTING IMAGING TO CARE
Corporate Presentation
March 2019
2
Disclaimer
This document has been prepared by EOS imaging (the "Company") and is provided for information purposes only. It shall not be construed as or considered as constituting or giving any investment advice. It does not take into account, in any way whatsoever,the investment objectives, financial situation or specific needs of its recipients who/which should not base their investment decision on this document.
This presentation and its contents may not be copied or disseminated, in part or as a whole, without prior written consent of the Company. This presentation includes only summary information and does not purport to be comprehensive.
The information and opinions contained in this document speak only as of the date of this document and may be updated, supplemented, revised, verified or amended, and such information may be subject to significant changes. EOS imaging is not under anyobligation to update the information contained herein and any opinion expressed in this document is subject to change without prior notice. The Company and its affiliates, advisors, representatives or employees shall not have any liability whatsoever (innegligence or otherwise) for any loss whatsoever arising from any use of this document or its contents, or otherwise arising in connection with this document.
The information contained in this document has not been independently verified. No representation, warranty or undertaking, express or implied, is made as to the accuracy, completeness or appropriateness of the information and opinions contained in thisdocument. The Company, its subsidiary, its advisors and representatives accept no responsibility for and shall not be held liable for any loss or damage that may arise from the use of this document or the information or opinions contained herein.
This document contains information on the Company’s markets and competitive position, and more specifically, on the size of its markets. This information has been drawn from various sources or from the Company’s own estimates.
This presentation may contain forward-looking information and statements pertaining to the Company and its subsidiaries, and its and their results. Forward-looking information is not historical. It reflects objectives that are based on management’s currentexpectations or estimates and is subject to a number of factors and uncertainties, that could cause actual figures to differ materially from those described in the forward-looking statements including those discussed or identified in the documentation publiclyreleased by the Company, including its annual report. EOS imaging draws your attention to the fact that as forward-looking statements cannot under any circumstance be construed as a guarantee of the Company's future performance and that the Company’sactual financial position, results and cash flow, as well as the trends in the sector in which the Company operate may differ materially from those proposed or reflected in the forward-looking statements contained in this document. Furthermore, even if EOSimaging’ financial position, results, cashflows and developments in the sector in which the Company operates were to conform to the forward-looking statements contained in this document, such results or developments cannot be construed as a reliableindication of the Company's future results or developments. The Company does not undertake any obligation to update or to confirm projections or estimates made by analysts or to make public any correction to any prospective information in order to reflectan event or circumstance that may occur after the date of this presentation. A description of those events that may have a material adverse effect on the business, financial position or results of EOS imaging, or on its ability to meet its targets, appears in the"Risk Factors" section of EOS imaging Registration Document registered with the Autorité des Marchés Financiers.
Certain figures and numbers appearing in this document have been rounded. Consequently, the total amounts and percentages appearing in the tables are therefore not necessarily equal to the sum of the individually rounded figures, amounts or percentages.
This presentation is qualified in its entirety by the information contained in the Company ’ financial statements, the notes thereto and the related annual financial report. In case of a conflict, such financial statements, notes and financial reports must prevail.
By accepting this document you agree to be bound by the foregoing limitations.
This document does not constitute or form part of an offer to sell or to purchase securities or the solicitation of an offer to purchase securities in the United States of America or in any other jurisdiction. The securities mentioned in this presentation have notbeen and will not be registered under the U.S. Securities Act of 1933, as amended (the “Securities Act”) or under any other legislation of any jurisdiction in the United States of America and may not be offered or sold in the United States absent registration oran applicable exemption from registration under the Securities Act.
3
EOS imaging: EOSI.PA
Connecting Imaging to Care
~170 employees, including an R&D team of 45 engineers
Clearance to market in 51 countries incl. U.S. (FDA), Japan, China, and the European Union (CE), with >300 units installed worldwide
+25% CAGR over 2012-2018 with 2018 sales revenue of €35.3 million
Unique, innovative, low dose 2D/3D full body imaging and software solutions bridging the gap between imaging and orthopedic surgery
Targeting a ~€2 billion per year addressable market
Direct commercial presence and tactical partnerships with offices in Paris France (HQ), Cambridge Massachusetts, Montreal Quebec, Besançon France, Frankfurt Germany, and Singapore
Created from a technology developed by Dr Georges Charpak, awarded Nobel Prize in Physics, with growing medical endorsements, including >385 publications since 2012
4
Company Milestones
Continued Innovation and Growth
1992
1998
2007
2008
2012
2014
2017
2018
2019
Radiation detection technology used to create EOS imaging was awarded the Nobel Prize in Physics
Initial steps in medical radiology under Marie Meynadier’s leadership
EOS® receives CE mark, initial commercialization team established
FDA clearance received. First EOS systems installed in Europe and North America
EOS imaging listed on Euronext Paris (EOSI)
EOS imaging installs 100th
system globally and authorized to market in 48 countries
Receives FDA clearance on EOSapps surgical planning portfolio and launches EOS 3Dservices
100 EOS systems installed in U.S. and 300 systems globally. EOS Private Practice Program launched in U.S.
Mike Lobinsky transitions into CEO role
5
Management Team
Combined 140+ Years Medical Technology Experience
Mike Lobinsky – Chief Executive Officer
• 20+ years medical device experience including senior management positions at Smith and Nephew, Brainlab, Blue Belt Technologies, Stryker Corp
• Joined EOS imaging in 2017• Appointed CEO January 2019
Valerie Worrall - Chief Financial Officer
• 20+ years finance experience in the healthcare industry including Novartis and previously CFO of Balt
• Joined EOS imaging in 2018
Eric Maulave - Chief Operating Officer
• 25+ years experience including business engineer for the IT and multimedia sectors and international Sales and Marketing Director within the Philips Group
• Joined EOS imaging in 2012
Didier Saint-Felix - Transformation Director
• 30+ years experience in the research and development of innovative medical imaging systems.
• Began his career at the French National Center for Scientific Research (CNRS) and then led R&D at General Electric Healthcare
• Joined EOS imaging in 2006
Kären Solie - Vice President Global Marketing
• 25+ years marketing experience in the medical device industry including senior marketing and market development positions at Stryker, Mako Surgical, superDimension, Covidien (Medtronic), Smith & Nephew and AxoGen
• Joined EOS imaging in 2018
Maurice Delplanque- Vice President of Engineering
• 20+ years experience in R&D and engineering in the healthcare industry
• Contributed to the development of the first digital radiography of neurology and cardiovascular systems at General Electric Healthcare
• Joined EOS imaging in 2007
6
EOS Orthopedic Solution
Low Dose Orthopedic Imaging + 3D Reconstruction + Surgical Planning & Patient Engagement
Imaging 3D Services 3D Surgical Planning & Patient Engagement
EOS systemBiplanar, low dose image capture
Imaging center takes full-body images in a standing or seated position
3D Services3D modeling of musculoskeletal system
Physicians visualize in 3D & obtain a patient-specific dataset of 100+ clinical parameters
automatically
EOSapps 3D surgical planning & patient engagement
Surgeons access surgical simulation and planning from 3D models and data sets
7
The EOS Orthopedic Continuum of Care
Images and Data for Spine, Hip and Knee Conditions and Surgeries
8
Differentiated Orthopedic Imaging Platform
Addressing Weaknesses in Conventional Imaging
1Patients treated for Adolescent Idiopathic Scoliosis had an overall cancer rate 5 times higher than of an age matched populationIncidence of cancer in adolescent idiopathic scoliosis patients treated 25 years previously, Simony A et al. Eur Spine J. 2016
EOS Platform X-ray: CR/DR CT Scanner MRI Ultrasound
Low dose1P P P
3D imaging P P* P*
Full-body(no stitching) P P P
Weight-bearing P P P
Low cost P P
*Only available in non functional positions
EOS Xray
Continuous, full-body imaging
Imprecise, stitched imaging
Bone imaging Soft tissue imaging
Current orthopedic imaging modalities
Exam time cut up to 80% vs
Xray
Dose cut2-10x
vs Xray
9
EOSapps Gaining Traction in Orthopedic Surgery Planning
Web-based, 3D Planning & Simulations of Surgical Outcome
spineEOS› Open architecture (currently) – able to add
vendor specific CAD screws, cages, rods, other
› 3D rod information exportable to rod bender or 3D printer
hipEOS› 3D range of motion simulations of surgical
outcome based on pre-op plan› Better understand patient’s hip & spine
relationship and identify patients at risk of early revision/dislocation
kneeEOS› Real time optimization of knee alignment and surgical
strategy› Automatic proposal of implant size and position according
to EOS images and 2D/3D patient dataset› Open platform, enables compatibility with all primary TKA
implants
Provides for inventory management and optimal instrument set logistics
10
Unique Benefits For All Stakeholders
Patients & Parents
Physicians & Surgeons
Hospitals, Systems& Private Practices
› Bias free clinical parameters, improved planning, correct sizing or choice of implant
› Unique weight-bearing 3D reducing CT imaging needs and providing enhanced understanding of condition
› 2D & 3D data for advanced surgery planning, execution and post-op validation
› Faster exams saving up to 80% time
› Standard of care for ALARA exams
› Key asset to differentiate a hospital’s orthopedic franchise in a competitive environment3
› Reimbursed with existing reimbursement codes
› 3D surgical planning facilitates operational efficiencies
1 1. Diagnostic imaging of spinal deformities: Reducing patients radiation dose with a new slot-scanning x-ray imager. Deschenes S, Charron G, Beaudoin G, Miron M, Labelle H, and Dubois J. et al. Spine. 20102As Low As Reasonably Achievable380% of US hospitals installed in 2017 ran a marketing campaign to inform local community on EOS availability at their facility
› Safer with irradiation 2-10x lower than traditional x-rays1
› Personalized plan for all patient anatomies
› Increased patient engagement from easy to share images
› Increased patient trust from ALARA2
dose commitment
11
~€2b Addressable Market Opportunity
1More than 100 joint orthopedic and/or 30 complex spine surgeries per year, worldwide estimation2Considering: services charged at €200 per surgery with 200 surgeries per EOS platform per year & 1 platform per site
€0,7b €0.5b €0.5b
Equipment +
• €400k ASP• Renewal market for
7 year lifetime• 12,000 sites with
significant orthopedic surgery volumes1
• €45k per unit • Online services and consumables2 (patient specific instruments)
€1.7b
Total
€0.7b
Maintenance Services =
12
Global Sales Channels and Strategic Partnerships
Addressable Market Represents ~12,000 EOS Systems Worldwide
Co-marketing program
Partnership associating EOS equipment to implant volumes in multi-year implant procurement contracts
Direct Sales Distributors & Agents Strategic Partnerships
13
Over 300 Systems Installed Worldwide , of which over 100 in the U.S.
EMEA45.1%NAM
38.6%
Asia-Pac.16.0%
Lat. Am*0.3%
(1)
+18% 2018 Installed Base Growth
+23%2018 Installed Base Growth
+48%2018 Installed Base Growth
+100%2018 Installed Base Growth
*1st system installed in 2017 + one additional one installed in 2018
+ 25% installed base growth in 2018
14
› Privately owned orthopedic practices operate their own imaging equipment
› 10 private practices purchased EOS
Expansion Beyond Hospital Market
Growing Adoption in Imaging Centers & Orthopedic Private Practices France: 72 EOS Installed 60% In Private Imaging Centers
› 2/3 of radiologists are in private sector
› Serving orthopedic surgery private clinics
Australia: 20 EOS Installed70% In Private Imaging Centers
Germany: 13 EOS Installed 40% In Private Settings
› Serving orthopedic private clinics
U.S.: 110 EOS InstalledLaunched Orthopedic Private Practice Program
› Serving orthopedic surgery hospitals and private clinics
15
U.S. Market Opportunity
~2% Penetration Rate
~ 1,000 tier one hospitals
~ 5,000 hospitals
(w/ inpatient treatment)
~100+ installed
Private Ortho Groups Practice
~ 750 tier one Practices
~ 1,600 private practices
(w/o inpatient treatment)
10+ installed
16
Increasing Adoption by Top Ranked Hospitals in U.S.
Proven Solution Drives Repeat System Purchases
EOS in the 25 Best Orthopedic Hospitals:84% of the Pediatric Hospitals64% of the General Hospitals
EOS in the top 10 Best Hospitals Honor Roll:90% of the Pediatric Hospitals80% of the General Hospitals
Constant growth of sites with more than 1 EOS system
4th HSS system to be installed in 2019
17
U.S. Private Orthopedic Practice Adoption
• «EOSone» program launched in 2018 (EOS program customized for Private Ortho Practice setting)• Benefits for clinics:
• Leverage EOS technology to differentiate practice and ASC• Offer end to end imaging to planning to surgery solution• Fair financial Return On Investment • Increased referrals
EOSone Program Components
EOS Private Practice Locations
18
• EOS Maintenance Agreements • Increasing subscription rate driving accelerated growth in
maintenance contracts
• Advanced Orthopedic Services (3DServices and EOSapps Surgical Planning)*• 30+% of current U.S. customer base under contract • Initial “try and buy” programs converting to future revenues • Including AOS “starter offering” in all EOS system sales• Implant company library growing
Recurring Revenue Acceleration
EOS Maintenance and Software Services Traction
*EOS also has a legacy PSI business (ca. €0.9m) which is stable and not a development focus
19
Sales of €35.3m in 2018
Recurring revenues represented 25% of total sales in 2018, compared to 10% of total sales in 2012
25% CAGR
Revenue growth
20
Revenues by Product and Region
Revenues Noted in €
21
Pillars of Growth
SalesTeam tenure and opportunity
pipeline in place to deliver growth
Business Development2019 is expansion year
for 3DServices & EOSapps
Product DevelopmentContinuing to expand end to end
portfolio
› Development of sales pipeline by new team in 2018 to deliver growth plans in 2019 and beyond
› Chinese distributor change to enhance EOS focus and coverageacross China
› Advanced Orthopedic Solutions (AOS) organization in place to drive accelerated market adoption in 2019
› Expecting 2018 AOS trial agreements to convert to purchase
› Ongoing discussions with implant companies
Continued development on differentiated EOS orthopedic solution
› AI / Machine Learning
› Predictive analytics
› Pre op surgical simulation
› EOS Apps portfolio enhancements
CONNECTING IMAGING TO CARE
Contact:
Phone: +33 (0)1 55 25 60 60
Email: [email protected]
www.eos-imaging.com
March 2019