correction: msln gene silencing has an anti-malignant effect on … · 2018. 1. 27. · alessandra...
TRANSCRIPT
CORRECTION
Correction: MSLN gene silencing has an anti-
malignant effect on cell lines overexpressing
mesothelin deriving from malignant pleural
mesothelioma
Ombretta Melaiu, Justin Stebbing, Ylenia Lombardo, Elisa Bracci, Norihisa Uehara,
Alessandra Bonotti, Alfonso Cristaudo, Rudy Foddis, Luciano Mutti, Roberto Barale,
Federica Gemignani, Georgios Giamas, Stefano Landi
In Fig 4A, the incorrect image is used for siMSLN-1. Please see the correct Fig 4 here.
PLOS ONE | https://doi.org/10.1371/journal.pone.0180317 June 22, 2017 1 / 3
a1111111111
a1111111111
a1111111111
a1111111111
a1111111111
OPENACCESS
Citation: Melaiu O, Stebbing J, Lombardo Y, Bracci
E, Uehara N, Bonotti A, et al. (2017) Correction:
MSLN gene silencing has an anti-malignant effect
on cell lines overexpressing mesothelin deriving
from malignant pleural mesothelioma. PLoS ONE
12(6): e0180317. https://doi.org/10.1371/journal.
pone.0180317
Published: June 22, 2017
Copyright: © 2017 Melaiu et al. This is an open
access article distributed under the terms of the
Creative Commons Attribution License, which
permits unrestricted use, distribution, and
reproduction in any medium, provided the original
author and source are credited.
Fig 4. Role of MSLN in cellular migration and invasion. A. No effects observed in the wound-healing assay, following siRNA
transfections. Confluent monolayers of Mero-14 cells transfected with 40 nM of siCtrl, or siMSLN-1, respectively. Two different
experiments were carried out, each performed in triplicate. B. Trans-well cell invasion assay on Mero-14 cells transfected with 40
nM of the siCtrl (top), or siMSLN-1 (bottom). Pictures were taken using a fluorescence microscope at 10X magnification and are
reported as negative of the originals to enhance the contrast between the background and the DAPI-stained cells. The bar chart
shows the average of invasive cells (error bars represent SEM of two independent experiments, each done in triplicate,
*P = 0.0044).
https://doi.org/10.1371/journal.pone.0180317.g001
PLOS ONE | https://doi.org/10.1371/journal.pone.0180317 June 22, 2017 2 / 3
Reference1. Melaiu O, Stebbing J, Lombardo Y, Bracci E, Uehara N, Bonotti A, et al. (2014) MSLN Gene Silencing
Has an Anti-Malignant Effect on Cell Lines Overexpressing Mesothelin Deriving from Malignant Pleural
Mesothelioma. PLoS ONE 9(1): e85935. doi:10.1371/journal.pone.0085935 PMID: 24465798
PLOS ONE | https://doi.org/10.1371/journal.pone.0180317 June 22, 2017 3 / 3