cosmetic - biochim.it cosmetics actives.pdfprotects skin and cosmetic products against...
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RAHN-GROUP – SPECIALISING IN MARKET-ORIENTATED COSMETIC ACTIVE SUBSTANCES SINCE 1999RAHN AG is a financially independent Swiss family company with three business areas, Cosmetics, EnergyCuring and Scent & Taste. RAHN AG has been a key player in the interna-tional marketplace since 1940 and has more recently grown into an internationally acclaimed expert in the development and sale of speciality chemicals.
In 1999 RAHN launched its own cleverly devised RAHN-Cosmetic Actives for use in a variety of applications.
RAHN-COSMETIC ACTIVES – A HOLISTIC PLATFORM SATISFYING INDIVIDUAL CUSTOMER REQUIREMENTSWe at RAHN speak the language of cosmetic science and strive to generate new inspiration for our customers. This message is reflected in RAHN-Cosmetic Actives where we recognise and harness the potential of nature, whilst combining it with modern technology to generate market-orientated, tried and tested active concepts. Constantly at the cutting edge of skin biology, we transform our scientifically proven systems into cosmetic statements. With its extensive platform, RAHN-Cosmetic Actives is capable of meeting a wide range of customer requirements be it in terms of marketing, science, product development or product safety.
UNCOMPLICATED CUSTOMER SERVICE – SECOND NATURE TO US!Our customers are at the very heart of our business and we recognise the importance of responding swiftly to customer requests to offer workable solutions. The documentation for RAHN-Cosmetic Actives is comprehensive and practical. Our customers are delighted to use the intelligent trade names on their cosmetic packaging to further enhance pack claims. We are also equipped to deal with formulation problems in our technical applications laboratory as well as providing a wide range of tailor-made, state-of-the-art formulations.
SOOTHING/ANTI-INFLAMMATORY
MOISTURISING
Product Overview
CELLACTIVE®-HYDROThe Apple-fresh Moisturiser
AQUARICH®
Moisture & Care for Skin & Hair
CLEOMILK®
Phyto-milk for Moisture & Care
HYDRACTIN®
Moisture & Energy
DEFENSIL®
Normalises Sensitive SkinDEFENSIL®-PLUSFirst Aid for Inflamed Skin
CELLACTIVE®-WHITELightening Skin Care WHITENING/SKIN LIGHTENINGILLUMISCIN®
Illuminates Skin by Eliminating Age Spots
You can click on the picture of the active which guides you directly to the productpage on our website where you can find our documents.
TARGET APPLICATIONS CELLACTIVE®-FORMFirming & Forming
CELLACTIVE®-MENHigh Performance Male Skin Care
SEBOCLEARTM-DBNormalises the Skin
PERFELINE®
Perfects Eyes & BodySLIMEXIR®
The Silhouette-Refiner
ANTI-CELLULITE/SLIMMING CELLACTIVE®-SHAPEReduces Orange Peel Skin
WHITENING/SKIN LIGHTENING
ProtectionAGE20+ 30+ 35+ 40+ 45+ 55+
RADICARE®
Early prevention for young, delicate skin. Potent free-radical scavenger for all ages
CELLIGENT® Intelligent skin protection to help fight the signs of ageing and prevent Formul’Ageing
Functional SupportAGE20+ 30+ 35+ 40+ 45+ 55+
MYRAMAZE®
Fast regeneration and invigoration of stressed skin thanks to the unique metabolic properties of a resurrection plant
LIFTONIN®-XPRESSInstant, intensive and long-lasting lifting-effect
PROTEOLEA®
Inspired by Nobel Prize Winning Biologyto rebalance the first signs of time
LIFTONIN®
Skin tightening and wrinkle reducing agent
ILLUMISCIN®
Prevention and reduction of age spots
REFORCYL®
Barrier strengthe-ning for very dry and mature skin in need of regene-ration
NEW
LIFTONIN®-XPRESSThe Instant Wrinkle Minimiser
LIFTONIN®
Cosmetic Lifting
CELLIGENT®
Intelligent Skin Protection
ANTI-AGEING
RADICARE®
Powerful Antioxidant
REFORCYL®
Nutrition & Resistance for Mature Skin
PROTEOLEA®
6 Years Younger in 4 Weeks
MYRAMAZE®
An Oasis of Wellbeing for Desert-like Skin
NEW
3R A HN - COSME T IC AC T I V ES
Gro
up Anti-Ageing Protection Functional Support
Prod
uct
CELLIGENT®
Intelligent Skin ProtectionRADICARE®
Powerful AntioxidantMYRAMAZE®
An Oasis of Wellbeing forDesert-like Skin
PROTEOLEA®
6 Years Younger in 4 Weeks
Scie
ntifi
cally
Con
firm
ed E
ffec
ts
Effective cell and DNA protection during solar irradiation (in-vitro study)
Stem cell protection (in-vitro study)
Rapid regeneration of UV-related cell and DNA damage (in-vivo study)
„After Sun Rescue Treatment“ (user test)
Protects skin and cosmetic products against Formul‘Ageing (ex-vivo study)
Reduces the formation of a wide range of ROS (in-vitro study)
Prevents oxidative cell damage even at low doses (in-vitro study)
Effectively inhibits the formation of free radicals (in-vivo study)
Protects membranes during dehydration (in-vitro study)
Protects skin lipids from oxidation (in-vitro study)
Revives the skin for longer than 48 hours after a single application (in-vivo study)
Rehydrates dry skin, strengthens the weakened skin barrier, revitalises sensi-tive skin, visibly and noticeably improves skin texture (in-vivo study)
Activates the proteasome (in-vitro study)
Improves stress resistance (in-vitro study)
Slows down cellular skin ageing (in-vitro study)
Improves skin hydration, skin roughness and skin cell renewal (in-vivo study)
Rejuvenates the eye area by 6 years within 4 weeks (in-vivo study)
Perceivably counteracts the signs of ageing (controlled user test)
INCI
Helianthus Annuus (Sunflower) Seed Oil, Ethyl Ferulate, Polyglyceryl-5 Trioleate, Rosmarinus Officinalis (Ro-semary) Leaf Extract, Water, Disodium Uridine Phosphate, Tocopherol
Water, Melissa Officinalis Leaf Extract, Disodium Rutinyl Disulfate, Sodium Benzoate, Hordeum Distichon (Barley) Extract, Citric Acid
Propanediol, Water, Myrothamnus Flabellifolia Extract, Ascorbic Acid, Citric Acid
Glycerin, Water, Levan, Decyl Glucoside, Olea Europaea (Olive) Leaf Extract, Phe-nethyl Alcohol, Zizyphus Jujuba Seed Extract, Citric Acid, Ascorbic Acid
Use
Lev
el
0.5 – 4 % 0.2 – 5 % 1 – 5 % 1 – 5 %
Appl
icat
ions
Anti-ageing products, skin care prod ucts for sun protection, after-sun products. Suitable for O/W and W/O emulsions and gels.
Anti-ageing products, repair products, sun formulations, after sun products, intensive care products. Suitable for O/W and W/O emulsions and gels.
Anti-ageing products; regeneration products for stressed, dehydrated, da-maged, irritated skin; suitable for O/W and W/O emulsions, gels and lotions.
Anti-ageing products for face and body. Suitable for O/W and W/O emulsions gels and lotions.
Ori
gin Plant, biotechnological, synthetic Plant, synthetic Plant, biotechnological origin Plant, biotechnological, synthetic
Nat
ural
Co
smet
ics
Chin
a Ap
prov
ed
NEW
comp
liant
comp
liant
comp
liant
comp
liant
listed
ECOCERT
listed
ECOCERT
4 YOUR PA RTNER F OR E XCELLENCE
Anti-Wrinkle / Lifting
REFORCYL®
Nutrition & Resistance for Mature Skin
LIFTONIN®-XPRESSThe Instant Wrinkle Minimiser
LIFTONIN®
Cosmetic Lifting
Activation of LXR in human primary keratinocytes (in-vitro study)
Activation of key enzymes involved in epidermal lipid synthesis (in-vitro study)
Improvement of hydration, firmness, elasticity and smoothness of skin (in-vivo study)
Visible improvement of wrinkle depth in eye area (in-vivo study)
Smoothes various types of wrinkles around the eye area, forehead and hands (in-vivo studies)
Improves the micro relief in the eye area, hands and arms (in-vivo studies)
Provides an immediately noticeable and long lasting tightening effect (in-vivo study)
More homogeneous skin appearance (in-vivo study)
Reduction of wrinkles and fine lines (in-vivo study)
Glycerin, Water, Glutamine, Decyl Glucoside, Phenethyl Alcohol, Citric Acid, Cistus Incanus Flower/Leaf/Stem Extract, Gynostemma Pentaphyllum Leaf/Stem Extract
Hydroxypropyl Methylcellulose, Pullu-lan, Porphyridium Cruentum Extract
Water, Glycerin, Panicum Miliaceum (Millet) Seed Extract, Citric Acid, Tannic Acid, Potassium Sorbate
1 – 5 % 0.5 – 3 % 2 – 5 %
Anti-ageing products for mature skin.Suitable for O/W and W/O emulsions, gels and serums.
Lifting products and tightening face and body care products. Suitable for O/W and W/O emulsions, gels and lotions.
Anti-ageing products for reducing wrinkles and lines. Suitable for O/W and W/O emulsions and gels.
Plant, biotechnological Plant, biotechnological Plant, synthetic
comp
liant
comp
liant
comp
liant
listed
COSMOS
listed
ECOCERT
comp
liant
NATRUE
5R A HN - COSME T IC AC T I V ES
Gro
up Moisturising
Prod
uct
AQUARICH®
Moisture & Care for Skin & Hair
CELLACTIVE®-HYDROThe Apple-fresh Moisturiser
CLEOMILK®
Phyto-milk for Moisture & Care
HYDRACTIN®
Moisture & Energy
Scie
ntifi
cally
Con
firm
ed E
ffec
ts
Deeply effective and long-lasting improvement in skin hydration (in-vivo study)
Better hydration effect than glycerin or hyaluronic acid (in-vivo study)
Hair repair effect: improvement in hair structure, prevention of split ends, improvement in hair gloss and bounce back (ex-vivo and in-vivo studies)
Effective hair care for animal hair (ex-vivo study)
12 hour long-term moisture effect (in-vivo study)
Reduced appearance of scaly skin (in-vivo study)
Strengthening of skin tissue (in-vivo study)
Reduces skin lipid removal when washing and promotes re-lipidation after washing (in-vivo study)
Accelerates the regeneration of the skin barrier (in-vivo study)
Protects against dehydration and reduces TEWL (in-vivo study)
Immediate improvement in skin moisture level of up to + 38 % after 1 hour (in-vivo study)
Long-term improvement in skin moisture level of up to 14 % after 28 days (in-vivo study)
INCI
Glycerin, Water, Avena Strigosa Seed Extract, Lecithin, Potassium Sorbate, Citric Acid
Glycerin, Water, Pyrus Malus (Apple) Fruit Extract, Phenoxyethanol, Pectin, Chlorella Vulgaris/Lupinus Albus Protein Ferment, Citric Acid
Sesamum Indicum (Sesame) Seed Oil, Water, Glycerin, Sucrose Stearate, Glyceryl Caprylate, Nigella Sativa Seed Oil, Xanthan Gum, Aloe Barbadensis Leaf Juice Powder, Citric Acid, Toco-pherol, Helianthus Annuus (Sunflower) Seed Oil, p-Anisic Acid
Glycerin, Water, Disodium Adenosine Triphosphate, Carica Papaya (Papaya) Fruit Extract, Phenoxyethanol, Algin, Sodium Hydroxide
Use
Lev
el Skin Care 1 – 5 %Hair Care 0.2 – 2 %
0.5 – 4 % 1 – 5 % 2 – 8 %
Appl
icat
ions
Moisturising care for skin and hair. Suitable for O/W and W/O emulsions, gels, shampoo and hair conditioners.
Moisturising skin care for face and body. Suitable for O/W and W/O emul-sions and gels.
Washing gels, shower gels, washing lotions, washing creams, liquid soaps for use on face and body. Suitable for O/W emulsions and gel bases.
Moisturising skin care for face and body. Suitable for O/W and W/O emul-sions and gels.
Ori
gin Plant, synthetic Plant, biotechnological, synthetic Plant, biotechnological Plant, biotechnological, synthetic
Nat
ural
Co
smet
ics
Chin
a Ap
prov
ed
comp
liant
comp
liant
comp
liant
comp
liant
listed
COSMOS
comp
liant
NATRUE
listed
ECOCERT
6 YOUR PA RTNER F OR E XCELLENCE
Soothing / Anti-Inflammatory Whitening / Skin Lightening
DEFENSIL®
Normalises Sensitive SkinDEFENSIL®-PLUSFirst Aid for Inflamed Skin
CELLACTIVE®-WHITELightening Skin Care
ILLUMISCIN®
Illuminates Skin by Eliminating Age Spots
Prevents cutaneous hyper-reactivity (in-vivo study)
Imparts immediate soothing (in-vivo study)
Effectively regenerates the skin barrier (in-vivo study)
AddendumProtects epidermal stem cells (in-vitro study)
Nips inflammatory processes in the bud (in-vitro study)
Reduces allergic reactions (in-vitro study)
Reduces tissue damage resulting from Mosquito bites (in-vivo study)
Soothes the skin after shaving and epilation (in-vivo study)
Protects and regenerates the damaged skin barrier (in-vivo study)
Improves the quality of life of those suffering from atopic eczema (in-vivo study)
Reduces the severity of couperose(in-vivo study)
Inhibition of melanin production (in-vitro study)
Lighter complexion (in-vivo study)
Activates the proteasome (in-vitro study)
Prevents the formation of lipofuscin (in-vitro study)
Reduces the size and the contour contrast of age spots (in-vivo study)
Promotes depigmentation and prevents repigmentation of age spots (in-vivo study)
Octyldodecanol, Echium Plantagi-neum Seed Oil, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Tocopherol
Octyldodecanol, Ribes Nigrum (Black Currant) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil Unsaponifia-bles, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Tocopherol, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract
Water, Alcohol Denat., Niacinamide, Zinc PCA, Chlorella Vulgaris/Lupinus Albus Protein Ferment, Nasturtium Officinale Flower/Leaf Extract
Glycerin, Water, Olea Europaea (Olive) Leaf Extract, Ascorbyl Glucoside, Zinc PCA, Ascorbic Acid
1 – 5 % 1 – 5 % 3 – 10 % 2 – 6 %
Sensitive skin care products, post- depilation products, intensive care products, baby products, pre-shaving products, after-sun products and lip balms.
Products to protect or prevent the appearance of sensitive, irritated skin in need of regeneration. Suitable for O/W and W/O emulsions, gels and lotions.
Skin lightening products for face and body. Suitable for O/W and W/O emul-sions and gels.
Age spot reducing skin care for face and body. Can be used in gels, emul-sions (O/W and W/O) and aqueous solutions.
Plant, synthetic Plant Plant, biotechnological, synthetic Plant, biotechnological
comp
liant
comp
liant
comp
liant
comp
liant
listed
COSMOS
listed
ECOCERT
comp
liant
NATRUE
7R A HN - COSME T IC AC T I V ES
Gro
up Anti-Cellulite / Slimming
Prod
uct
CELLACTIVE®-SHAPEReduces Orange Peel Skin
PERFELINE®
Perfects Eyes & BodySLIMEXIR®
The Silhouette-Refiner
Scie
ntifi
cally
Con
firm
ed E
ffec
ts
Stimulation of lipolytic activity (in-vitro study)
Reduction of fat infiltration in the dermis (in-vivo study)
Improvement of skin micro-relief (in-vivo study)
Stimulates fat degradation (in-vitro study)
Reduces fat infiltration into the dermis (in-vivo study)
Reduces dark circles and eye puffiness (in-vivo study)
Prevents formation of new adipocytes (in-vitro study)
Reduces lipid accumulation in adipo-cytes (in-vitro study)
Stimulates degradation of existing fat (in-vitro study)
Triggers fragmentation of lipid droplets (postulated mechanism) (in-vitro study)
Leads to a significant reduction of abdomen volume (in-vivo study)
INCI
Water, Alcohol Denat., Caffeine, Coleus Forskohlii Root Extract, Chlorella Vul-garis/Lupinus Albus Protein Ferment, Citric Acid
Water, Carnitine, Caffeine, Ruscus Aculeatus Root Extract, Citric Acid, Potassium Sorbate, Sodium Benzoate
Water, Levan, Cynara Scolymus (Arti-choke) Bud Extract, Decyl Glucoside, Phenethyl Alcohol, Citric Acid, Gluco-se, Caffeine, Theobromine, Methyl Xanthine, Paraxanthine
Use
Lev
el 1 – 4 % 3 – 8 % 2 – 10 %
Appl
icat
ions
Body care products for the treatment of cellulite to achieve a fine silhouette. Suitable for O/W and W/O emulsions and gels.
Body care products to treat cellulite and achieve a fine silhouette.Suitable for O/W and W/O emulsions and gels.
Body care products to refine the silhouette and re-contour the body. Suitable for O/W and W/O emulsions, gels and lotions.
Ori
gin Plant, biotechnological, synthetic Plant, biotechnological, synthetic Plant, biotechnological, synthetic
Nat
ural
Co
smet
ics
Chin
a Ap
prov
ed
✔ ✔ ✔comp
liant
comp
liant
comp
liant
8 YOUR PA RTNER F OR E XCELLENCE
Target Applications
CELLACTIVE®-FORMFirming & Forming
CELLACTIVE®-MENHigh Performance Male Skin Care
SEBOCLEARTM-DBNormalises the Skin
Activation of lipid accumulation – lipogenesis in human adipocytes (in-vitro study)
Increased breast volume accentuates femininity and lends fullness to the cleavage (in-vivo study)
Improved skin elasticity in the cleavage area, firms the breast and smoothes its surface (in-vivo study)
Accelerated healing of micro shaving cuts (in-vitro study)
Increased cell resistance to extreme conditions; cold shock and heat stress (in-vitro study)
Powerful skin moisturising with long-lasting effect (in-vivo study)
Effectively reduces existent skin impurities and optimises the skin appearance (in-vivo study)
Water, Glycerin, Alcohol Denat., Phen-oxyethanol, Garcinia Mangostana Peel Extract, Chlorella Vulgaris/Lupinus Albus Protein Ferment, Pyrus Cydonia Seed Extract, Maltodextrin
Water, Glycerin, Taurine, Phenoxy-ethanol, Chlorella Vulgaris/Lupinus Albus Protein Ferment, Acanthopanax Senticosus (Eleuthero) Root Extract
Water, Alcohol Denat., Sodium Salicylate, Plantago Lanceolata Leaf Ex-tract, Mahonia Aquifolium Root Extract
Skin Firming 2 – 5 %Breast Volume Enlargement 5 – 8 %
2 – 5 % 2 – 8 %
Cleavage care for firming and beautify-ing the skin texture as well as special care for breast enlargement. Suitable for O/W and W/O emulsions and gels.
.
Products for the care of male skin;especially for facial and moisturising care, anti-age, aftershave and body care. Suitable for O/W and W/Oemulsions and gels.
Products for impure skin; face cleans-ing, tonics, spot pads, acne swabs, cover up pens, hair lotions. Suitable for O/W and W/O emulsions and gels.
Plant, biotechnological, synthetic Plant, biotechnological, synthetic Plant, synthetic
✔ ✔ ✔comp
liant
comp
liant
comp
liant
9R A HN - COSME T IC AC T I V ES
Age-
Spot
s-Re
duct
ion
Anti-
Agei
ng
Anti-
Coup
eros
e
Anti-
/ Inf
lam
m-A
gein
g
Anti-
Stre
ss
Anti-
Wrin
kle /
Lift
ing
Barr
ier
Repa
ir / R
egen
erat
ion/
Nut
ritio
n
Dar
k Ci
rcle
s / E
ye P
uffin
ess
Déc
olle
té
Det
oxify
ing
Firm
ing
Hai
r Ca
re
Mat
ure
Skin
Men
Met
abol
ic A
ctiv
atio
n / E
nerg
y
Moi
stur
isin
g
Prot
ectio
n (D
NA
/Fre
e Ra
dica
ls / S
tem
Cel
ls)
Seb
um R
egul
atio
n/An
ti-Ac
ne
Slim
min
g / A
nti-C
ellu
lite
Soot
hing
/ Ant
i-Inf
lam
mat
ory
Whi
teni
ng / S
kin
Ligh
teni
ng
AQUARICH®
CELLACTIVE®-FORM
CELLACTIVE®-HYDRO
CELLACTIVE®-MEN
CELLACTIVE®-SHAPE
CELLACTIVE®-WHITE
CELLIGENT®
CLEOMILK®
DEFENSIL®
DEFENSIL®-PLUS
HYDRACTIN®
ILLUMISCIN®
LIFTONIN®
LIFTONIN®-XPRESS
MYRAMAZE®
PERFELINE®
PROTEOLEA®
RADICARE®
REFORCYL®
SEBOCLEARTM-DB
SLIMEXIR®
Natural Cosmetics
Applications
NEW
11R A HN - COSME T IC AC T I V ES
Our
Distributors
CanadaAndicor Specialty Chemicals590 Abilene DriveMississauga, Ontario L5T 2T4
Ms. Andrea [email protected]
www.andicor.com
USAKinetik Technologies8 Crown Plaza, Suite 110Hazlet, NJ 07730
Ms. Adrienne [email protected]
www.kinetiktech.com
BrazilM.CASSAB Comércio e Industria LtdaAv. das Nacoes Unidas, 20.882Santo Amaro 04975-000 Sao Paulo
Ms. Andrea Adams [email protected]
www.mcassab.com.br
Greece, Serbia, Slovenia, Bosnia, Macedonia, Croatia, Romania and BulgariaAvel Ltd.Larissis Str. 515121 Pefki Athen
Mr. Stamatis [email protected]
www.avel.gr
South AfricaSiyeza Fine Chem (Pty) Ltd.7 Bessemer Road AmalgamPO Box 39383Booysens 2016
Ms. Allison [email protected]
www.siyezafine.co.za
Finland, Latvia, Estonia, LithuaniaOy Flinkenberg AbP.O.Box 69 (Mikkelänkallio 3)FI-02771 Espoo
Mr. Simon Riihelä[email protected]
www.flinkenberg.fi
ItalyBIOCHIM S.r.l.Via Puccini 81IT-20080 Casarile (MI)
Mr. Giovanni [email protected]
www.biochim.it
Spain, PortugalKumara CosmeticsTarragona 10608015 Barcelona
Ms. Vanessa [email protected]
www.kumara.es
TurkeySurya Kimya Sanayi Ticaret Ltd. StiMaresal Fevzi Cakmak Ca. G-22 Sk. No.52Ferhatpasa- Atasehir / Istanbul
Ms. Mine [email protected]
www.surya.com.tr
12 YOUR PA RTNER F OR E XCELLENCE
ChinaGuangzhou Hongrunda Trading Co. Ltd.Room D4-5, 5/F,Jian Fa Guang Chang,111 Airport Road,Guangzhou 510403
Mr. George [email protected]
www.hongrunda.net (non-operating)
MalaysiaIngredients Plus Sdn Bhd18, Jalan Anggerik Mokara 31/51, Kota Kemuning40460 Shah Alam, Selangor Darul Ehsan,
Mr. Chai Sien [email protected]
www.ingredientsplus.com.my
JapanToyo Science Corp.Kinsan Bldg., 1-21Nihonbashi Muromachi 4-chome103-0022 Tokyo
Mr. Hidenori [email protected]
www.toyo-asia.co.jp
ThailandChemico Inter Corporation Co., Ltd.1, Soi Ladprao 101, Soi 42, Yak 1,Klongchan, Bangkapi, Bangkok 10240
Mr. Ekkarin [email protected]
www.chemicogroup.com
PhilippinesChemico Philippines Inc.Mezzanine Fl., Republic Glass Building,196 Salcedo St.,Legaspi Village, Makati City, 1229.Philippines Ms. Anrovelyn M. [email protected]
www.chemicogroup.com
TaiwanChem Best Industries Inc.No. 15, Wu Chuan 6th RoadWu Ku Industrial ParkTaipei
Mr. Mark [email protected]
www.chemeagle.com.tw
South KoreaHANJOO C&C Co., Ltd.#1205 Byucksan Technopia, 13,Ojeongongup-gil, Uiwang-si, Gyeonggi-do,KOREA 437-821
Mr. Kris [email protected]
www.hanjoocnc.co
SingaporeIngredients Plus Pte Ltd9, Temasek Boulevard#09-01, Suntec Tower TwoSingapore 038989
Mr. Chai Sien [email protected]
www.ingredientsplus.com.my
IndonesiaPT. Kemiko IndonesiaInfinia Park Blok B-87JI, Prof. Dr. Saharjo No. 45Jakarta Selatan, 12850
Ms. Toyo [email protected]
www.chemicogroup.com
Australia and New ZealandCarst & Walker Australia Pty Ltd.Unit 1/5 Iron Street, Malaga WA 6090
Ms. Malie [email protected]
www.carst.com.au
IndiaArihant Innochem Pvt. Ltd.606, 607, 6th floor, B wing, Express Zone,Western Express Highway, near Dindoshi flyover,Goregoan (E) Mumbai – 400 063 INDIA
Ms. Prema Roy [email protected]
www.arihantinnochem.com
13R A HN - COSME T IC AC T I V ES
Gro
up Moisturising
Prod
uct
AQUARICH®
Moisture & Care for Skin & Hair
CELLACTIVE®-HYDROThe Apple-fresh Moisturiser
CLEOMILK®
Phyto-milk for Moisture & Care
HYDRACTIN®
Moisture & Energy
Scie
ntifi
cally
Con
firm
ed E
ffec
ts
Deeply effective and long-lasting improvement in skin hydration (in-vivo study)
Better hydration effect than glycerin or hyaluronic acid (in-vivo study)
Hair repair effect: improvement in hair structure, prevention of split ends, improvement in hair gloss and bounce back (ex-vivo and in-vivo studies)
Effective hair care for animal hair (ex-vivo study)
12 hour long-term moisture effect (in-vivo study)
Reduced appearance of scaly skin (in-vivo study)
Strengthening of skin tissue (in-vivo study)
Reduces skin lipid removal when washing and promotes re-lipidation after washing (in-vivo study)
Accelerates the regeneration of the skin barrier (in-vivo study)
Protects against dehydration and reduces TEWL (in-vivo study)
Immediate improvement in skin moisture level of up to + 38 % after 1 hour (in-vivo study)
Long-term improvement in skin moisture level of up to 14 % after 28 days (in-vivo study)
INCI
Glycerin, Water, Avena Strigosa Seed Extract, Lecithin, Potassium Sorbate, Citric Acid
Glycerin, Water, Pyrus Malus (Apple) Fruit Extract, Phenoxyethanol, Pectin, Chlorella Vulgaris/Lupinus Albus Protein Ferment, Citric Acid
Sesamum Indicum (Sesame) Seed Oil, Water, Glycerin, Sucrose Stearate, Glyceryl Caprylate, Nigella Sativa Seed Oil, Xanthan Gum, Aloe Barbadensis Leaf Juice Powder, Citric Acid, Toco-pherol, Helianthus Annuus (Sunflower) Seed Oil, p-Anisic Acid
Glycerin, Water, Disodium Adenosine Triphosphate, Carica Papaya (Papaya) Fruit Extract, Phenoxyethanol, Algin, Sodium Hydroxide
Use
Lev
el Skin Care 1 – 5 %Hair Care 0.2 – 2 %
0.5 – 4 % 1 – 5 % 2 – 8 %
Appl
icat
ions
Moisturising care for skin and hair. Suitable for O/W and W/O emulsions, gels, shampoo and hair conditioners.
Moisturising skin care for face and body. Suitable for O/W and W/O emul-sions and gels.
Washing gels, shower gels, washing lotions, washing creams, liquid soaps for use on face and body. Suitable for O/W emulsions and gel bases.
Moisturising skin care for face and body. Suitable for O/W and W/O emul-sions and gels.
Ori
gin Plant, synthetic Plant, biotechnological, synthetic Plant, biotechnological Plant, biotechnological, synthetic
Nat
ural
Co
smet
ics Ecocert: listed
COSMOS: listedNaTrue: certified
6 YOUR PA RTNER F OR E XCELLENCE
Soothing / Anti-Inflammatory Whitening / Skin Lightening
DEFENSIL®
Normalises Sensitive SkinDEFENSIL®-PLUSFirst Aid for Inflamed Skin
CELLACTIVE®-WHITELightening Skin Care
ILLUMISCIN®
Illuminates Skin by Eliminating Age Spots
Prevents cutaneous hyper-reactivity (in-vivo study)
Imparts immediate soothing (in-vivo study)
Effectively regenerates the skin barrier (in-vivo study)
AddendumProtects epidermal stem cells (in-vitro study)
Nips inflammatory processes in the bud (in-vitro study)
Reduces allergic reactions (in-vitro study)
Reduces tissue damage resulting from Mosquito bites (in-vivo study)
Soothes the skin after shaving and epilation (in-vivo study)
Protects and regenerates the damaged skin barrier (in-vivo study)
Improves the quality of life of those suffering from atopic eczema (in-vivo study)
Reduces the severity of couperose(in-vivo study)
Inhibition of melanin production (in-vitro study)
Lighter complexion (in-vivo study)
Sustained reduction of Lipofuscin formation (in-vitro study)
Reduction of total area of age spots by 14.2 % after 2 weeks and 21.2 % after 3 months (in-vivo study)
Reduction of contour sharpness of age spots by 13.5 % after 3 months (in-vivo study)
Octyldodecanol, Echium Plantagi-neum Seed Oil, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Tocopherol
Octyldodecanol, Ribes Nigrum (Black Currant) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil Unsaponifia-bles, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Tocopherol, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract
Water, Alcohol Denat., Niacinamide, Zinc PCA, Chlorella Vulgaris/Lupinus Albus Protein Ferment, Nasturtium Officinale Flower/Leaf Extract
Glycerin, Water, Olea Europaea (Olive) Leaf Extract, Ascorbyl Glucoside, Zinc PCA, Ascorbic Acid
1 – 5 % 1 – 5 % 3 – 10 % 3 – 7 %
Sensitive skin care products, post- depilation products, intensive care products, baby products, pre-shaving products, after-sun products and lip balms.
Products to protect or prevent the appearance of sensitive, irritated skin in need of regeneration. Suitable for O/W and W/O emulsions, gels and lotions.
Skin lightening products for face and body. Suitable for O/W and W/O emul-sions and gels.
Age spot reducing skin care for face and body. Can be used in gels, emul-sions (O/W and W/O) and aqueous solutions.
Plant, synthetic Plant Plant, biotechnological, synthetic Plant, biotechnological
Ecocert: listedCOSMOS: listedNaTrue: certified
7R A HN - COSME T IC AC T I V ES
RAHN-documents are available in English, German and French. For more details click on our webpage www.rahn-group.com or contact your local RAHN-sales representative for further information.
SwiSS ExpErtiSE
coSmEtic activES
PRODUCT OVERVIEW (ENGLISH)
PRODUCT BROCHURE (ENGLISH, GERMAN)Detailed brochure including comprehensive information about skin biology, ingredients, treatment concept, effi-cacy studies and test formulations
Other notable ingredients include soluble saccharide compounds such as trehalose and arbutin.
Figure 3a: Trehalose, a natural preservative for biological molecules, membranes and proteins. Trehalose is a disac-charide consisting of two α, α’-1,1-glycosidically-linked glucose molecules.
Trehalose Arbutin
Figure 3b: Arbutin, a phenolic molecule with a glucose residue. Arbutin protects cell membranes from oxidative damage.
Arbutin has antioxidant properties and prevents lipid per-oxidation in the cell membrane. This maintains the rigidity and the integrity of the cell membrane and therefore pre-serves the cell viability during and after physical stress [23]. Arbutin is also used for skin lightening in cosmetics. The molecular mechanism of action is based on the inhibition of melanin synthesis by inhibition of the enzyme tyrosinase [24]. However, the use of arbutin in cosmetics is viewed crit-ically and is not without controversy [25, 26]. We wish to emphasise that the content of arbutin in MYRAMAZE® is not a health concern under the intended conditions of normal use.
Trehalose can strengthen and preserve a wide spectrum of biological molecules. Thus trehalose acts as a kind of natural means of protection against desiccation, oxidation, heating and frost. It is not surprising that trehalose accumulates in ex-actly those organisms which can survive for long periods with-out damage in non-vital state [20–22].
8 M Y R A M A ZE ®
The appearance of the skin depends on the water content. In the outermost layers, this is usually between 10 and 40 %. Adequate water content helps the skin to be even, soft and elastic. However, if water content is too low, it will be scaly, rough and cracked. Sufficient water is important not only for the skin’s appearance but also for a sufficient barrier func-tion: balanced water content makes the penetration of hy-drophobic substances into the skin difficult.
Desiccation threatens not just Myrothamnus flabellifolia, but also the skin: if the ambient air has less water available than the skin itself, the skin will be constantly losing moisture to the environment by evaporation (= transepidermal water loss, TEWL). This causes drying of the skin. Drastic environ-mental conditions such as low temperatures or low humidity in the winter contribute significantly to dehydration. There-fore it is hardly surprising that the stress factor “dry skin” is a widespread problem. However, dry skin is not just an aes-thetic problem; it also provides a good breeding ground for mild irritation, chronic skin diseases or itching.
Cosmetic importance
Figure 4: MYRAMAZE® stabilises the skin’s physiological moisture and lipid barrier and protects the cells from dryness. This has two advantages: first, MYRAMAZE® promotes quick skin regeneration after difficult and stressful times in which the skin was either treat-ed badly or it was simply ignored. Sec-ond, MYRAMAZE® increases the skin’s resistance to future external influences.
MYRAMAZE® is made to protect the skin’s cells against dryness and to sta-bilise the skin’s moisture and lipid bar-rier. Thus, MYRAMAZE® effectively in-creases the skin’s resistance to irritation and promotes a speedy re-covery. The skin is protected in times of “drought”, and after the first “down-pour” it flourishes again in the shortest possible amount of time.
Protectsagainst oxidation
DrynessHeat/Cold
Weather/WindSolarisation
H2O2
O2
.-
O2
.- OH.
OH.
H2O2
H2O2
H2O2
O2
.-
H2O2
O2
.-
H2O
Strengthens cellularmembrane
Stabilises proteins and enzymes
9A N OA SIS OF WELLBEING F OR DESERT- L IK E SK IN
MYRAMAZE®
An Oasis of Wellbeing for Desert-like Skin
MYRAMAZE® DEFENSIL®-PLUS
4 DEFENSIL®- PLUS
Figure 1: The inflammatory reaction in the skin. If the cells are damaged by trauma or foreign substances penetrate into the tissue, the cells of the skin react with the release of alarm signals. They thereby initiate an inflammatory re-sponse, which aims to protect the body from invaders and to repair the damage.
Inflammation–protectivereactionofthebody
Aninflammationisacharacteristicresponseoftheskintis-suetoanexternal,potentiallyharmfulirritation.Itsjobistoeliminatethisirritanttopreventitsspreadandtopotentiallyrepairanyresultantdamage(Figure1).InflammationcomesfromtheLatinwordinflammatio.Thereisaspecificnomen-clatureforinflammationswhicharerestrictedtospecificre-gionsofthebody:TheyarenamedafterthecombinationoftheGreektermfortheaffectedorganandtheGreekending-itis:forexample,dermatitis(skininflammation)orarthritis(joint inflammation). Inflammations canbe either acuteorchronic. The acute inflammations have a dramatic start,reachtheirclimaxinashortamountoftimeandthereac-tionusuallyendswithinminutesorafewdaysmaximum.Ifthebodyisunabletorapidlyneutralisetheirritatingagent,theacuteformcandevelopintoaninsidious,chroniccondi-tion.
1. Irritation(Mosquito Bites, Shaving, Allergen)
2. Damaged orinfected cells
3. Alarm Signalsfrom injured cells,e.g. IL-1
5. Lymphocyte(Immune Response)
6. Platelet(Wound Closure)
Blood Vessel
4. Phagocyte &Granulocyte(ROS, DefenceMolecules)
5F IR S T A ID F OR INFL A MED SK IN
Figure 2a: The release of Arachidonic acid is one of the first steps in the inflammatory response. Arachidonic acid is released by the enzyme Phospholipase A2 from the cell membrane lipids. An example of a phosphatidyl-choline with Arachidonic acid and of the unsaturated Oleic acid is shown. Arachidonic acid is the starting substance for a vari-ety of inflammatory mediators. The enzyme Phospholipase A2 is also present in some insect poisons, which explains the severe skin reaction after a wasp sting, for example.
Theacuteinflammatoryresponse
Thetriggerofaninflammatoryresponseisalwaysanirritationofthetissuewhichcanbecausedbythefollowingstimuli:• Mechanical stimuli(foreignbody,pressure,injury)• Physical stimuli(ionisingradiation,UVlight,heat,cold),• Chemical stimuli(alkalis,acids,heavymetals,bacterialtoxins,allergens)
• Biological stimuli(bacteria,viruses,fungi,worms,insects)• Other stimuli,includingabnormalmetabolism,abnormalenzymes,malignanttumour
Ifthestimulusexceedsacertainthreshold,thebodyreactswithaninflammatoryresponse.Thelipidsofthecellmem-braneusuallyareattheverybeginningoftheinflammatorycascade.Duetotheirritationofthetissue,Arachidonicacidis released from them (Figure 2a). Arachidonic acid is thebasicbuildingblockfortheformationofmostofthealarmsignals or inflammatory mediators (Eicosanoids: Leukot-rienesandProstaglandins)thatnowfollow.Theseandothermediatorsinitiateanddrivethenextstepsoftheinflamma-tory response (Figure2b):Phagocytes (suchasMonocytesandNeutrophils)migratethroughthevesselwalls intothetissuetoeliminatetheinflammatorystimulusandthedam-aged cells. Other cells such as Mast cells or Basophils releasesubstances (suchasHistaminesorCytokines) thatact as mediators of inflammation, specifically in terms of recruitment(=attract)ofotherbloodcellssuchasLympho-cytesandMonocytes.Lymphocytesarethemostimportantagentsofthespecificimmunesystem;theyarealsorespon-sible for the formation of specific antibodies against the inflammatorystimulus.
Alarm Signals/Inflammatory Mediators(Eicosanoids)
O
O
N+P
C
O581114
61
Arachidonic Acid
ω
OH
C
O
C
O
O CH
O CH
CH2
Phospholipase A2
O
Double Lipid LayerApolar Polar DEFENSIL®-PLUS FirstAidforInflamedSkin
Available
Documents
14 YOUR PA RTNER F OR E XCELLENCE
MYRAMAZE® DEFENSIL®-PLUS
PRODUCT LEAFLET (ENGLISH)Four page product summary
SCIENTIFICALLY PROVEN EFFECTS• Protects membranes during dehydra-
tion (in-vitro study) • Protects skin lipids from oxidation
(in-vitro study) • Revives the skin for longer than
48 hours after a single application (in-vivo study)
• Rehydrates dry skin, strengthens the weakened skin barrier, revitalises sensitive skin, visibly and noticeably improves skin texture (in-vivo study)
O2
.-OH.
H2O
2
O2
.-O
2
.-
O2
.- OH.
OH.
OH.
H2O
2
H2O
2
H2O
2
H2O
2
Prevention of Lipid OxidationPlasticising of Membranes
Protection of Enzymes and Proteins
Stabilisation of Water and Lipid Barrier
Lipid OxidationMembrane Damage
Enzyme Deformation
Weak Water and Lipid Barrier
Trehalose
Dry SkinEasy-to-irritate Skin«Desert-like» Skin
Fast RegenerationBetter Resistance against Stress
H2OH
2ODryness
Heat/Cold
Weather/WindSolarisation H
2OH
2ODryness
Heat/Cold
Weather/WindSolarisation
Galloyl QuinicAcid
MODE OF ACTION
• Polyphenols• Trehalose• Arbutin
• Protect skin lipids (cell membrane and extracellular lipid matrix) from oxidation
• Protect cell membrane from damage caused by desiccation
• Traditional use: activity against asthma and allergic reactions, burn- and wound-healing
ACTIVE INGREDIENTS
Quinic acid derivatives (3,4,5-tri-O-galloylquinic acid)
Further active ingredients
MYRAMAZE® stabilises membranes and protects membrane lipids from oxidative damage. This leads to a more rapid re-generation and invigoration of stressed skin.
O
OH
OH
OH
HO
HO OH
R
2HO
HO
O
OOH
O
O
O
HO
OH
O
OH
OH
OH
OH
HO
O
HO
OH
HO
O
MYRAMAZE® PROTECTS MEMBRANES DURING DEHYDRATION (in-vitro study)
Method: Simulation of a stress situation (desiccation / rehyd-ration) for calcein (fluorescence dye) encapsulated liposomes; Membrane stability was measured by monitoring fluorescence intensity.Implementation: Addition of MYRAMAZE® or placebo (propane-diol) to liposomes; desiccation (15 h); rehydration (phosphate buffer resp. test substances); the higher the fluorescence values, the higher the membrane damage.Result: MYRAMAZE® protects liposomal membranes against de-siccation / rehydration and maintains membrane integrity.
MYRAMAZE® MEASURABLY AND VISIBLY REVITA-LISES ATTACKED SKIN (in-vivo study)
Method: Tewameter / assessment by dermatologists / macro photographs;Implementation: 20 test persons with attacked, chronically dry skin; 19 – 74 years; twice daily application of a gel with 2 % MYRAMAZE® or placebo (0 % MYRAMAZE®) for a period of 10 days; skin measurements and photographs taken at the be-ginning and at the end of the study; dermatological assessment done at the beginning, in the middle and at the end of the study.Result: MYRAMAZE® significantly improves the condition of attacked and stressed skin: it strengthens the skin barrier, regenerates the skin after only five days, reduces redness and improves skin texture.
Application and Processing InformationAnti-Ageing products, products to regenerate stressed skin. Suitable for gels and emulsions (O/W and W/O). MYRAMAZE® is water soluble and should be processed at temperatures < 50° C.
Recommended Use Level: 1 – 5 %
INCI: EU: Propanediol, Aqua, Myrothamnus Flabellifolia Extract, Ascorbic Acid, Citric Acid; USA: Propanediol, Water, Myrotham-nus Flabellifolia Extract, Ascorbic Acid, Citric Acid; Japan: Pro- panediol, Onsen-Sui, Myrothamnus Flabellifolia Extract, Ascorbic Acid, Citric Acid
Preservation: None
Natural Cosmetics: Ecocert: listed
Mean Fluorescence
MYRAMAZE®
Placebo
100%
Before After
-60%***
-52%***
0
5000
10000
15000
+23%
-63%100%
Before After
Mean + SEM; Experiment was performed in duplicate
Membrane Disruption Before and AfterDesiccation/Rehydration
Increase in Barrier Strength
Relative to Initial Condition (%)
PlaceboMYRAMAZE®***
Mean + SEM;n = 20;*** = p < 0.0010
5
10
15
20
25
+19%
Skin Regeneration
Relative to Initial Condition (%)
p=0.08
PlaceboMYRAMAZE®
*
Mean + SEM;n = 20; * = p < 0.05;*** = p < 0.001
*
***
-20
0
20
40
60
80 ***
Day 5 Day 10 Day 5 Day 10
▲ Day 10▲ Day 0
MODE OF ACTION
• Valuable Phytosterols• Skin soothing• Plant-derived alternative to
Hydrocortisone
• High level of unsaponifiable substances (bioactive compounds)
• Rich in essential Fatty Acids (Linoleic Acid)
• Stabilises skin barrier
• Rich in ω-3/6-Fatty Acids (Stearidonic Acid; γ-Linolenic Acid)
• Strengthens skin barrier• Soothes inflammation
ACTIVE INGREDIENTS
DEFENSIL®-PLUS eases inflammatory processes and supports the recovery of the skin barrier.
SCIENTIFICALLY PROVEN EFFECTS • Nips inflammatory processes in the
bud (in-vitro study) • Reduces allergic reactions
(in-vitro study) • Reduces tissue damage resulting
from Mosquito bites (in-vivo study) • Soothes the skin after shaving and
epilation (in-vivo study) • Protects and regenerates the dama-
ged skin barrier (in-vivo study) • Improves the quality of life of those
suffering from atopic Eczema (in-vivo study)
Blackcurrant Seed Oil Sunflower Oil Concentrate Ballon Vine Extract
Strong BarrierReduced Sensitivity/
Anti-inflammatory Environment
Reduced Tissue DamageReduced Discomfort
Prevention of Inflamm-ageingPrevention of Sensitive Skin
Stearidonic AcidPhytosterols
Linoleic Acidγ-Linolenic Acid
Reduction of Inflammation
Barrier DeficiencyHypersensitivity/
Pro-inflammatory Environment
Inflammation
ShavingAllergen
Mosquito Bites
Tissue DamageDiscomfort
Inflamm-ageingSensitive Skin
ShavingMosquito Bites
Allergen
Vici
ous
Cir
cle
DEFENSIL®-PLUS REDUCES TISSUE DISORDER RESULTING FROM MOSQUITO BITES (in-vivo study)
Method: Measurement of the quaddle area following bites from the common house Mosquito. Self experiments.Implementation: In each test run approx. 10 bite areas were treated (Cream with 5 % DEFENSIL®-PLUS/Placebo) or left untreated following the appearance of the first symptoms. After 30 min the area of the swellings was determined by means of digital images.Result: SOS-treatment with DEFENSIL®-PLUS relieves the intensity of Mosquito bites by 35 %.
DEFENSIL®-PLUS IMPROVES THE SKIN CONDITION IN ATOPIC ECZEMA (in-vivo study)
Method: Objective assessment of the skin condition by a der-matologist before and after application of a cream with 3 % DEFENSIL®-PLUS by means of local SCORAD (= SCORing Atopic Dermatitis: Sum of various parameters, each on a scale from 0 – 3.Implementation: 34 subjects, 17 – 60 years old, SCORAD > 4; 2x daily (arms, legs, trunk) or 4x daily (hands) application of DEFENSIL®-PLUS; determination of objective SCORAD on Days 0, 7 and 14; subjective assessment of quality of life.
Application and Processing InformationProducts to protect or prevent the appearance of sensitive, irritated skin in need of regeneration. Suitable for use in emulsi-ons, gels and lotions. DEFENSIL®-PLUS is oil soluble and should be processed at temperatures < 50°C.
Recommended Use Level: 1 – 5 %
INCI: EU: Octyldodecanol, Ribes Nigrum Seed Oil, Helianthus Annu-us Seed Oil Unsaponifiables, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Tocopherol, Helianthus Annuus Seed Oil, Rosma-rinus Officinalis Leaf Extract; USA / Japan: Octyldodecanol, Ribes Nigrum (Black Currant) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Tocopherol, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract.
Preservation: None
Natural Cosmetics: Ecocert: listed; COSMOS: listed; NaTrue: certified
0
1
2
3
4
5
6
7
8
Mean + SEM; n = 34 * = p < 0.05*** = p < 0.001
Local SCORADErythemaLichenificationDrynessOthersItching
-47%-37%
***
*
***
Day 0 Day 7 Day 14
-60%***
-52%***
0
10
20
30
40
Total Quality of LifeQoL Impairment Score
-42%***
Day 0Day 14
Mean + SEM;n = 34;*** = p < 0.001
Result: Within short time, DEFENSIL®-PLUS significantly improves the skin condition, reduces itching and brings 42 % more quality of life to those suffering from atopic Eczema.
DEFENSIL®-PLUSUntreated
Placebo
0.0
0.5
1.0
1.5
2.0
Skin Irritation after Mosquito BiteQuaddle Area (cm2)
*
Mean + SEM; 2 testsubjects; n = 8–14* = p< 0.05
p = 0.09UntreatedPlaceboDEFENSIL®-PLUS 5 %
-35%
Sensitive, hot and itchy skin often is caused by excessive
inflammation which affects skin barrier function and eventually
can lead to accelerated skin ageing (inflamm-ageing) as well as
impaired quality of life.
DEFENSIL®-PLUS is a highly effective first-aid kit to alleviate
stressed, sensitive and irritable skin. The outstanding properties
of Blackcurrant Seed oil and Balloon Vine extract in combination
with Sunflower Oil Concentrate effectively reduce inflammatory
processes and replenish the damaged skin barrier. DEFENSIL®-PLUS soothes various forms of skin irritation;
acute irritation as a result of razor burn, or from Mosqui-
to bites are both significantly reduced. Chemically irritated
skin also is protected and gently regenerated. In summary,
DEFENSIL®-PLUS markedly relieves dry, itchy, allergy-prone
skin and gives those plagued by Eczema a new lease of life.
DEFENSIL®-PLUS First Aid for Inflamed Skin
In the desert-like environment of South Africa, there lives a res-
ilient resurrection plant, Myrothamnus flabellifolia, which has a
unique adaptation strategy: in spite of its extreme environment,
it can survive long and hot periods of drought in a completely
desiccated state and become green again within a few hours of
the first drops of rain. The resurrection properties of M. flabel-
lifolia are based on physical stabilisation (such as leaf morpho-
logy, cell-wall composition etc.) and metabolic adaptation. As
an example, water loss increases the production of protective
constituents such as galloylquinic acids.
This resurrection effect can also be applied to the skin:
MYRAMAZE®, an extract of Myrothamnus flabellifolia, is like an
oasis for stressed, “desert-like” skin with a particularly high pro-
portion of protective substances. It protects membrane struc-
tures from dehydration and preserves the most important skin
lipid linoleic acid, against oxidation. A one-time application of
MYRAMAZE® invigorates the skin for more than 48 hours. With
regular use, MYRAMAZE® effectively revives, regenerates and
strengthens skin that is stressed, attacked and depleted.
MYRAMAZE®
An Oasis of Wellbeing for Desert-like Skin
PRODUCT PRESENTATION (ENGLISH, GERMAN, FRENCH)
An Oasis of Wellbeing for Desert-like Skin MYRAMAZE®
First Aid for Inflamed Skin DEFENSIL®-PLUS
MYRAMAZE® DEFENSIL®-PLUS
4
Myrothamnus flabellifolia A resilient desert plant
• Lives in South Africa on rock slabs • Shrub (about 60 cm of height) with unique adaptation
strategy • Survives long periods of drought thanks to
extraordinary desiccation tolerance • Resurrection plant: is alive and green within short time,
when the first drops of rain fall • Use in traditional medicine
Coughs / colds (tea) Wounds / burns / abrasions (application of leaves) Skin irritations (ointments)
/ MYRAMAZE® 2
I’m at ease in my Skin
/ DEFENSIL®-PLUS
Sensitive skin: irritated, hyper-reactive, stressed, intolerant, irritable Occurence (self assessment): 60 % of women / 40 % of men Causes: Inflammatory processes/ barrier damage Consequences: tension, itching, scratching, burning, inflamm-ageing, reduced quality of life Intelligent active ingredients:
ease symptomes AND improve quality of life
15R A HN - COSME T IC AC T I V ES
RAHN AGDörflistrasse 120
CH-8050 Zürich
Tel. +41 44 315 42 00
Fax +41 44 315 42 45
RAHN GmbH
Hahnstrasse 70
DE-60528 Frankfurt am Main
Tel. 0800 1 816 015
Fax 0800 1 816 016
RAHN (UK) Ltd.
75 Park Road
GB-Peterborough
PE1 2TN
Tel. 0800 0 323 743
Fax 0800 0 323 744
RAHN France
91 rue de Faubourg Saint-Honoré
FR-75008 Paris
Tel. 0800 913023
Fax 0800 918268
RAHN USA Corp.
1005 North Commons Drive
Aurora, Illinois 60504, USA
Tel. +1 630 851 4220
Fax +1 630 851 4863
www.rahn-group.com
DISCLAIMERUtilisation of this document or parts thereof as well as product names for commercial or industrial applications is subject to explicit written approval by RAHN AG. This information is based on our own experience to date and we believe it to be reliable. It is intended only as a guide to use at your discretion and risk. We cannot guarantee favourable results and assume no liability in connection with its use, or the use of the methods or products described. None of this information is to be taken as a license to operate under, or a recommendation to infringe patents.
Version: 06/2014