Publications List DDS/PhD Nicholas Dybal-Hargreaves Pavana RK, Shah K, Gentile T, Dybdal-Hargreaves NF, Risinger AL, Mooberry SL, Hamel E, Gangjee A. Sterically induced conformational restriction: discovery and preclinical evaluation of novel pyrrolo[3,2-d]pyrimidines as microtubule targeting agents. Bioorg Med Chem. 26:5470-5478, 2018 Michael Eskander Eskander MA, Takimoto K, and Diogenes A. Evaluation of mesenchymal stem cell modulation of trigeminal neuronal responses to cold. Neuroscience 2017; 360:61-67. PMID: 28757246 Eskander MA, Ruparel S, Green DP, Chen PB, Por ED, Jeske NA, Gao X, Flores ER, and Hargreaves KM. Persistent nociception triggered by nerve growth factor (NGF) is mediated by TRPV1 and oxidative mechanisms. Journal of Neuroscience 2015; 35(22):8593-8603. PMID: 26041925 Rowan MP, Bierbower SM, Eskander MA, Szteyn K, Por ED, Gomez R, Veldhuis N, Bunnett NW, Jeske NA. Activation of mu opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) via β-arrestin-2-mediated cross-talk. PLoS One 2014; 9(4):e93688. PMID: 24695785 Ruparel S, Hargreaves KM, Eskander M, Rowan S, de Almeida JF, Roman L, Henry MA. Oxidized linoleic acid metabolite-cytochrome P450 system (OLAM-CYP) is active in biopsy samples from patients with inflammatory dental pain. Pain 2013; 154(11):2363-2371. PMID: 23867730 Steven Farnsworth Farnsworth SL, Qiu Z, Mishra A, and Hornsby PJ. Optimization of Differentiation of Nonhuman Primate Pluripotent Cells Using a Combinatorial Approach. Methods Mol Biol. 2019; 1919:187-197. PMID: 30656630 Galeano, C. Qiu, Z. Mishra, A. Farnsworth, S.L. Hemmi, J. Moreira, A. Edenhoffer, P. and Hornsby P.J. The route by which intranasally delivered stem cells reach the central nervous system. Cell Transplantation (2018). Qiu, Zhifang, Mishra, Anuja, Li, Miao, Farnsworth, Steven L., Guerra, Bernadette, Lanford, Robert E., Hornsby, Peter J., Marmoset induced pluripotent stem cells: Robust neural differentiation following pretreatment with dimethyl sulfoxide, Stem Cell Research (2015), doi: 10.1016/j.scr.2015.05.010 PMID: 26070112. PMC4516655. Mishra, A. Qiu Z. Farnsworth, S. Hemmi, J. Li, M. Pickering, A. and Hornsby, P. Induced pluripotent stem cells from nonhuman primates. (2014) Methods Mol Biol [1064-3745]. PMID: 25540117

Farnsworth, S.L. Qiu, Z. and Mishra, A. and Hornsby, P.J. Directed neural differentiation of induced pluripotent stem cells from nonhuman primates. Experimental Biology and Medicine. 2013. PMID: 23598973, PMCID: PMC3737072. Qiu, Z. Farnsworth, S.L. Mishra, A. and Hornsby, P.J. Patient-specific induced pluripotent stem cells in neurological disease modeling: the importance of nonhuman primate models. Stem Cells and Cloning: Advances and Applications 2013:6 19–29. PMID: 24426786, PMCID: PMC3850364. Wu Y, Mishra A, Qiu Z, Farnsworth S, Tardif SD, Hornsby PJ. 2012. Nonhuman Primate-Induced Pluripotent Stem Cells in Regenerative Medicine. Stem Cells International; Article ID 767195. PMCID: PMC3345260. Nataliya Inozemtseva-Verona Function of DLX3 in Amelogenesis, Dissertation, N. Inozemtseva-Verona, UTHSCSA, Graduate School of Biomedical Sciences, August 2009 Mouse Amelogenin Exons 8 and 9: Sequence Analysis and Protein Distribution. P. Papagerakis, J.M. Ibarra, N. Inozemtseva, P. DenBesten1 and M. MacDougall* . Department of Pediatric Dentistry, Dental School, University of Texas Health Science Center San Antonio, MSC 7888, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA; and 1 Department of Growth & Development, Pediatric Dentistry Division, School of Dentistry, University of California San Francisco, San Francisco, CA; Journal of Dental Research, Vol. 84, No. 7, 613-617 (2005) Binding of two nuclear factors to a novel silencer element in human dentin matrix protein 1 (DMP1) promoter regulates the cell type-specific DMP1 gene expression. Chen S, Inozemtseva-Clayton N, Dong J, Gu TT, MacDougall M. Journal of Cellular Biochemistry, 92-2, 332-349, 2004 Suzette Laing Li G., Cang C., Laing SD., Ballard C et al. (2016). Hematopoietic Knockdown of PPARδ Ameliorates Atherosclerosis in LDLR-/- Mice. Gene Therapy, 23 78-85. PMCID: PMC4939901 2.Cang Chen; Xinhua Li; Biju Chandu; Suzette Laing et al. (2018). GDNF-expressing macrophages mitigate loss of dopamine neurons and improve Parkinsonian symptoms in MitoPark mice. Scientific Reports, 8(1) 54-60. PMID: 29615705 Audrey Rakian Sadasivan C, Cesar L, Seong, J, Rakian A, Hao Q, Tio F, Wakhloo AK, Lieber BB. An original flow diversion device for the treatment of intracranial aneurysms: evaluation in the rabbit elastase-induced model. Stroke, 40(3):952-958, 2009. PMCID: PMC2647586 Feng J, McDaniel JS, Chuang H, Huang O, Rakian A, Xu X, Steffensen B, Donly KJ, MacDougall M, Chen S. Binding of Amelogenin to MMP-9 and their Co-expression in Developmental Mouse Teeth. Journal of Molecular Histology, 43(5):473-85, 2012. PMCID: PMC3460178

Chen S, McDaniel JS, Feng J, Rakian A, and MacDougall M: DSPP gene transcription and cellular signaling pathways. In: Goldberg M (ed): Frontiers Between Science and Clinic in Odontology. Bentham Science Publishers, Oak Park, IL, Vol 2, pp.186-202, 2012. Sadasivan C, Brownstein J, Patel B, Dholakia R, Santore J, Al-Mufti F, Puig E, Rakian A, Fernandez-Prada K, Elhammady MS, Farhat H, Fiorella D, Woo H, Aziz-Sultan MA, Lieber BB. In Vitro quantification of the size distribution of intrasaccular voids left after endovascular coiling of cerebral aneurysms. Cardiovascular Engineering and Technology, 4(1):63-74. 2013. PMCID: PMC3653595 Rakian A, Yang W, Gluhak-Heinrich J, Cui Y, Harris MA, Villareal D, Feng JQ, MacDougall M, Harris SE. Bmp2 Gene Controls Tooth Root Development in Coordination with Formation of the Periodontium. International Journal of Oral Science, 5(2):75-84, 2013. PMCID: PMC3707077 Harris SE, Rediske M, Neitske R, and Rakian A. Periodontal Biology: Stem Cells, Bmp2 Gene, Transcriptional Enhancers, and Use of the Sclerostin Antibody, and Parathyroid Hormone for Treatment of Periodontal Disease and Bone Loss. Cell Stem Cells and Regen Med, 3(1), 2017. Renschler JS, Norsworthy GD, Rakian RA, Rakian AI, Wheat LJ, Hanzlicek AS. Reduced Susceptibility to Fluconazole in a Cat with Histoplasmosis. Journal of Feline Medicine and Surgery Open Reports, 3(2), 2017. PMCID: PMC5714094 Rakian A, Gluhak-Heinrich J, Cui Y, Feng JQ, Kalajzic I, Harris MA, Harris SE. Bmp2 Gene in Lineage Commitment and Differentiation of Periodontal Stem Cells. (In preparation) Rubie Rakian Rakian R, Block TJ, Johnson SM, Marinkovic M, Wu J, Dai, Dean DD, Chen XD. Native Extracellular Matrix Preserves Mesenchymal Stem Cell “Stemness” and Differentiation Potential Under Serum-free Culture Conditions. Stem Cell Res Ther. (2015) 6:235. (PMID: 26620283) (PMCID: PMC4666167) Marinkovic M, Block TJ, Rakian R, Li Q, Wang, E, Reilly MA, Dean D, Chen XD. One size does not fit all: Developing a cell-specific niche for in vitro study of cell behavior. Matrix Biology 52-54:426-41 (PMID: 26780725) Renschler JS, Norsworthy GD, Rakian RA, Rakian AI, Wheat LJ, Hanzlicek AS. Reduced susceptibility to fluconazole in a cat with histoplasmosis. Journal of Feline Medicine and Surgery Open Reports 3(2). (PMCID: PMC5714094) Rakian A, Rakian R, Gluhak-Heinrich J, Cui Y, Feng JQ, Kalajzic I, Harris MA, Harris SE. Bmp2 Gene in Lineage Commitment and Differentiation of Periodontal Stem Cells. Bone Research (In preparation) Nikita Ruparel Austah O, Joon R, Chrepa V, Diogenes A, Ezeldeen M, Couve E and Ruparel NB. Comprehensive Evaluation of 2 immature Teeth treated with Regenerative Endodontic Procedures. J Endod (in press) Vishwanat L, Duong R, Takimoto K, Phillips L, Espitia CO, Diogenes A, Ruparel SB, Kolodrubetz

D and Ruparel NB. Effect of Bacterial Biofilm on the Osteogenic Differentiation of Stem Cells of Apical Papilla. J Endod. 43: 916-922, 2017. PMID: 28416302 Parrone MR, Bechara B, Deahl ST, Ruparel NB, Katkar R and Noujeim M. Cone beam computed tomography image optimization to detect root fractures in endodontically treated teeth: an in vitro (phantom) study. Oral Surg Oral Med Oral Pathol Oral Radiol. 123: 613-620, 2017. PMID: 28407988 Song JS, Takimoto K, Jeon M, Vadakekalam J, Ruparel NB, Diogenes A. Decellularized Human Dental Pulp as a Scaffold for Regenerative Endodontics. J Dent Res. 96(6):640-646, 2017. PMID: 28196330 Austah ON, Ruparel NB, Henry MA, Fajardo RJ, Schmitz JE, Diogenes A. Capsaicin-sensitive Innervation Modulates the Development of Apical Periodontitis. J Endod. 42: 1496-1502, 2016. PMID: 27523907 Green D, Ruparel S, Gao X, Ruparel NB, Patil M, Akopian A, Hargreaves KM. Central activation of TRPV1 and TRPA1 by novel endogenous agonists contributes to mechanical allodynia and thermal hyperalgesia after burn injury. Mol Pain. 2016, DOI: 10.1177/1744806916661725. PMID: 27411353

Kim SH, Kim S, Shin Y, Lee HS, Jeon M, Kim SO, Cho SW, Ruparel NB, Song JS. Comparative Gene Expression Analysis of the Coronal Pulp and Apical Pulp Complex in Human Immature Teeth. J Endod. 42: 752-759, 2016. PMID: 27020968 Ruparel NB, Ruparel SB, Chen PB, Ishikawa B, Diogenes A. Direct effect of endodontic sealers on trigeminal neuronal activity. J Endod. 40: 683-687, 2014. PMID: 24767564 Ruparel NB, de Almeida JF, Henry MA, Diogenes A. Characterization of a stem cell of apical papilla cell line: effect of passage on cellular phenotype. J Endod. 39: 357-363, 2013. PMID: 23402507 Ruparel NB, Teixeira FB, Ferraz CC, Diogenes A. Direct effect of intracanal medicaments on survival of stem cells of the apical papilla. J Endod. 38: 1372-1375, 2012. PMID: 22980180 Ruparel NB, Patwardhan AM, Akopian AN, Hargreaves KM. Desensitization of transient receptor potential ankyrin 1 (TRPA1) by the TRP vanilloid 1-selective cannabinoid arachidonoyl-2 chloroethanolamine. Mol Pharmacol. 80:117-123, 2011. PMID: 21441412 Patwardhan AM, Akopian AN, Ruparel NB, Diogenes A, Weintraub ST, Uhlson C, Murphy RC, Hargreaves KM. Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents. J Clin Invest. 120: 1617-1626, 2010. PMID: 20424317 Jeske NA, Patwardhan AM, Ruparel NB, Akopian AN, Shapiro MS, Henry MA. A-kinase anchoring protein 150 controls protein kinase C-mediated phosphorylation and sensitization of TRPV1. Pain. 146: 301-307, 2009. PMID: 19767149 Akopian AN, Ruparel NB, Jeske NA, Patwardhan A, Hargreaves KM. Role of ionotropic cannabinoid receptors in peripheral antinociception and antihyperalgesia. Trends Pharmacol Sci. 30: 79-84, 2009. PMID: 19070372

Rowan MP, Ruparel NB, Patwardhan AM, Berg KA, Clarke WP, Hargreaves KM. Peripheral delta opioid receptors require priming for functional competence in vivo. Eur J Pharmacol. 602: 283-287, 2009. PMID: 19063879 Jeske NA, Diogenes A, Ruparel NB, Fehrenbacher JC, Henry M, Akopian AN, Hargreaves KM. A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1. Pain. 138: 604-616, 2008, 2008. PMID:18381233 Akopian AN, Ruparel NB, Patwardhan A, Hargreaves KM. Cannabinoids desensitize capsaicin and mustard oil responses in sensory neurons via TRPA1 activation. J Neurosci. 28: 1064-1075, 2008. PMID: 18234885 Ruparel NB, Patwardhan AM, Akopian AN, Hargreaves KM. Homologous and heterologous desensitization of capsaicin and mustard oil responses utilize different cellular pathways in nociceptors. Pain. 135: 271-279, 2008. PMID: 17590514 Akopian AN, Ruparel NB, Jeske NA, Hargreaves KM. Transient receptor potential TRPA1 channel desensitization in sensory neurons is agonist dependent and regulated by TRPV1-directed internalization. J Physiol. 583: 175-193,2007. PMID: 19070372 Diogenes A, Patwardhan AM, Jeske NA, Ruparel NB, Goffin V, Akopian AN, Hargreaves KM. Prolactin modulates TRPV1 in female rat trigeminal sensory neurons. J Neurosci. 26:8126-8136, 2016. PMID: 16885226

Ahmed Sabbah Kota S, Sabbah A, Chang TH, Harnack R, Xiang Y, Meng X, Bose S. Role of human beta defensin-2 during tumor necrosis factor-alpha /NF-kappa B mediated innate anti-viral response against human respiratory syncytial virus. J Biol Chem. 2008 Dela Cruz I, Sabbah A, Chang T, Harnack R, Mgbemena V, Chatterjee B, Bose S. Cancer Anticancer oncolytic activity of respiratory syncytial virus. Gene Ther. 2009 May 15 Sabbah A, Chang TH, Harnack R, Frohlich V, Tominaga K, Dube PH, Xiang Y, Bose S. Activation of innate immune antiviral responses by Nod2. Nat Immunol. 2009 Aug 23. Sabbah A, Bose S. Retinoic acid inducible gene I Activates innate antiviral response against human parainfluenza virus type 3. Virol J. 2009 Nov 17 Ibtissam Echchgadda, Te-Hung Chang , Ahmed Sabbah , Imad Bakri , Yuji Ikeno , Gene B Hubbard , Bandana Chatterjee and Santanu Bose. Oncolytic Targeting of Androgen-sensitive Prostate Tumor by the Respiratory Syncytial Virus (RSV): Consequences of Deficient Interferon-dependent Antiviral Defense, BMC Cancer 2011 Santanu Bose, Te-Hung Chang, Jesus Segovia, Ahmed Sabbah, Victoria Mgbemena Cholesterol Rich lipid rafts are required for release of infectious human respiratory syncytial virus particles. Virology Oct 2011 Segovia J, Sabbah A, Mgbemena V, Tsai SY, Chang TH, Berton MT, Morris IR, Allen IC, Ting JP, Bose S. TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection. PLoS One. 2012

Hicks J, Schaffer R, Frances D, Usher S, Barnes J, Sabbah A. Foreign service special care opportunity in SCDA. Spec Care Dentist. 2015 Aug 7. Sabbah A, Gardner W, MacNeill B. A retrospective analysis of implants success post restoration in HIV patients. (In preparation) Sabbah A, Hicks J, MacNeill B, Arbona A, Aguilera A, Gelfond J, Liu Q Gardner W. A retrospective analysis of implants survival in HIV patients. Accepted, Journal of Clinical Periodontology 2019 Sabbah A, William Hendricson. Electronic Formative-Summative Daily Clinical Evaluations in Competency Assessment and Calibration. (In preparation) Alimohammadi R, Sabbah A. Changes in the Fractal dimensions of peri-implant trabecular bone after loading. (In preparation) Geethanjali Vipulanandan Banerjee M, Uppuluri P, Zhao X, Carlisle P, Vipulanandan G, Villar C, López-Ribot J and Kadosh, D. Expression of UME6, a key regulator of C. albicans hyphal development, enhances biofilm formation via Hgc1- and Sun41-dependent mechanisms. Eukaryot. Cell. 12(2):224-232. (2013). PMCID: PMC3571304 Lackey E, Vipulanandan G, Childers DS, and Kadosh D. Comparative Evolution of Morphological Regulatory Functions in Candida Species. Eukaryot Cell. 2013 Aug 2. PMCID: PMC3811340 Vipulanandan G, Herrera M, Wiederhold NP, li X, Mintz J, Wickes BL and Kadosh D. Dynamics of Mixed-Canaida Species Biofilms in Response to Antifungals.Journal of Dental Research. 97(1):91-98. (2018). PMCID: PMC5755808 Ashley Wallace Grayson M, Wallace A, Ruparel S. Depiction of oral tumor-induced trigeminal afferent responses using single-fiber electrophysiology. Sci Reports. 2019 Jan. ahead of press. Ruparel S, Bendele M, Wallace A, Green D. Released lipids regulate transient receptor potential channel (TRP)-dependent oral cancer pain Mol Pain. 2015 May 26;11:30 PMID: 26007300 PMCID: PMC4456056 PhD Allison Brackley Brackley AD & Toney GM (2019) Increased respiratory depression sensitivity to clinically relevant opioids in a rat model of sleep apnea. In Submission Brackley AD, Flores EF, Gomez R, Guerrero KA, Jeske NA (2019) FDA-approved drug enhances delta opioid receptor competence in peripheral sensory neurons. In Submission Gomez R, Kohler DM, Brackley AD, Henry MA, Jeske NA (2018) Serum response factor mediates

nociceptor inflammatory pain plasticity. Pain Rep 3(3):e658 (PMID29922747:PMC5999410) Por ED, Sandoval ML, Thomas-Benson C, Burke TA, Doyle Brackley A, Jeske NA, Cleland JM, Lund BJ (2017) Repeat low-level blast exposure increases transient receptor potential vanilloid (TRPV1) and endothelin-1 (ET-1) expression in the trigeminal ganglion. PLoS One 12(8):e0182102 (PMID28797041:PMC5552217) Brackley AD, Gomez R, Guerrero KA, Akopian AN, Du J, Carlton SM, Jeske NA (2017) A-Kinase Anchoring Protein 79/150 Scaffolds Transient Receptor Potential A 1 Phosphorylation and Sensitization by Metabotropic Glutamate Receptor Activation. Scientific Reports 7 (1): 1842 (PMID 28500286:PMC5431798) Brackley AD, Sarrami S, Gomez R, Guerrero KA, Jeske NA (2017) Identification of a signaling cascade that maintains constitutive delta opioid receptor incompetence in peripheral sensory neurons. J Biol Chem 292(21):8762-8772 (PMID 28381559:PMC5448103) Brackley AD, Gomez R, Akopian AN, Henry MA, Jeske NA (2016) GRK2 constitutively desensitizes delta opioid receptor in the periphery. Cell Reports 16(10):2686-98 (PMID27568556:PMC5014669) Hallums DP, Gomez R, Doyle AP, Viet C, Schmidt BL, Jeske NA (2016) RKIP in expression and phosphorylation in oral cancer. Clin Surg 1:1100 (PMID28529999:PMC5436720) Rowan MP, Szteyn K, Doyle AP, Gomez R, Henry MA, Jeske NA (2014) β-arrestin-2-biased agonism of delta opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) in primary sensory neurons. Molecular Pain 10:50 (PMID:PMC4131480) Patricia Carlisle Banerjee M, Thompson DS, Lazzell A, Carlisle PL, Pierce C, Monteagudo C, López-Ribot JL, Kadosh D. 2008. UME6, a novel filament-specific regulator of Candida albicans hyphal extension and virulence. Mol. Biol. Cell; 19(4):1354-65. (PMCID: PMC2291399) Carlisle PL, Banerjee M, Lazzell A, Monteagudo C, López-Ribot JL, Kadosh D. 2009. Expression levels of a filament-specific transcriptional regulator are sufficient to determine Candida albicans morphology and virulence. Proc Natl Acad Sci USA; 106(2):599-604. Cover article, see commentary: Bastidas, R.J. and Heitman, J., Proc. Natl. Acad. Sci. USA; 106: 351-352 and HSC News article. (PMCID: PMC2626749) Carlisle PL, Kadosh D. 2011. Candida albicans Ume6, a filament-specific transcriptional regulator. Directs hyphal growth via a pathway involving Hgc1 cyclin-related protein. Eukaryot. Cell; 9:1320-1328. (PMCID: PMC2937344) Thompson DS*, Carlisle PL*, Kadosh D. 2011. Co-evolution of morphology and virulence in fungal pathogens. Eukaryot. Cell; Sep 10(9): 1173-82. (PMCID: PMC3187052) Banerjee, M., Zhao, X.R., Uppuluri, P., Carlisle, P.L., Vipulanandan, G., Lopez-Ribot., J.L., Villar. C.C. and Kadosh, D. (2013) Expression of UME6, a key regulator of C. albicans hyphal development, enhances biofilm formation via Hgc1- and Sun41-dependent mechanisms. Eukaryot. Cell. 12(2):224-32.

Carlisle, P.L. and Kadosh, D. (2013) A Genome-wide Transcriptional Analysis of the Candida albicans Reversible Yeast-Pseudohyphal-Hyphal Morphological Transition. Mol. Biol. Cell 24(3):246-60. Carlisle, P.L., Guda, T., Silliman, D.T., Lien, W., Hale, R.G. Brown Baer, P.R. (2016) Investigation of a Pre-Clinical Mandibular Bone Notch Defect Model in Miniature Pigs: Clinical CT, Micro-CT and Histological Evaluation. J Korean Assoc Oral Maxillofac Surg 42(1):20-30. Carlisle, P.L., Guda, T., Silliman, D.T., Hale, R.G. Brown Baer, P.R. (2015) Are critical size bone notch defects possible in the rabbit mandible? Accepted - Journal of The Korean Association of Oral and Maxillofacial Surgeons. Carlisle P, Guda T, Silliman DT, Burdette AJ, Talley AD, Alvarez R, Tucker D, Hale RG, Guelcher SA, BrownBaer PR. (2018) Localized low-dose rhBMP-2 is effective at promoting bone regeneration in mandibular segmental defects. J Biomed Mater Res B Appl Biomater. Epub ahead of print David Cavazos Cavazos DA. 2004. Type I ALT Telomere Maintenance in a Human Cell Line. Cancer Research, 2004. Marciniak RA, Cavazos DA, Montellano R, Chen Q, Guarente L, Johnson B, A Novel Telomere Structure in a Human Alternative Lengthening of Telomeres Cell Line. Cancer Research; 65(7): 2730-2737. (PMID: 15805272) Kazhdan I, Long L, Montellano R, Cavazos DA, RA Marciniak. 2006. Targeted Gene Therapy for Breast Cancer with Truncated Bid. Cancer Gene Ther; 13(2):141-149. (PMID: 16110313) Siddiqa A, Cavazos DA, Marciniak RA. 2006. Targeting Telomerase. Rejuvenation Res; 9(3): 378-390. (PMID: 16859479) Silva J, Cavazos DA, Donzis E, Friedrichs WE, Marciniak R, Degraffenried LA. 2007. AKT-Induced Tamoxifen Resistance is Associated with Altered FKHR Regulation. Cancer Investigations; 25(7):569-73. (PMID: 17952739) Cavazos DA, Price RS, Apte SA, deGraffenried LA. 2011. Docosahexaenoic Acid Selectively Induces Human Prostate Cancer Cell Sensitivity Through Modulation of NF-κB. Prostate; 71(13): 1420-1428. (PMID: 21360560) Price RS, Cavazos DA, de Angulo RA, Hursting SD, deGraffenried LA. 2011. Obesity-related Systemic Factors Promote an Invasive Phenotype in Prostate Cancer Cells. Prostate Cancer and Prostatic Diseases; 15(2): 135-43. (PMCID: PMC3321466) Siddiqa AI, Cavazos DA, Chavez J, Long LI, Marciniak RS. 2012. Modulation of Telomeres in Alternative Lengthening of Telomeres Type I Like Human Cells by the Expression of Werner Protein and Telomerase. Journal of Oncology; 2012: 806382. (PMCID: PMC3321466) de Angulo AS, Faris RA, Cavazos DA, Jolly CA, Daniel B, deGraffenried LA. Age-related Alterations in T-lymphocytes Modulate Key Pathways in Prostate Tumorigenesis. The Prostate, November 27th, 2012.

Apte SA, Cavazos DA, deGraffenried LA. A Low Dietary Ratio of Omega-6 to Omega-3 Fatty Acids may Delay Progression of Prostate Cancer. Nutrition and Cancer, January 5th, 2013 Bowers LW, Cavazos DA, Ilane MX, Brenner AJ, Hursting SD, deGraffenried LA. Obesity Enhances Nongenomic Estrogen Receptor Crosstalk with the PI3K/Akt and MAPK Pathways to Promote in vitro Measures of Breast Cancer Progression. Breast Cancer Research, June 10th, 2013. Cavazos DA, deGraffenried MJ, Apte SA, Bowers LW, Whelan KA, deGraffenried LA. Obesity Promotes Aerobic Glycolysis in Prostate Cancer Cells. Nutrition and Cancer, 66:7 1179-1186. Accepted April 9th, 2014. Aksenov A, Smirnov A, Magedov I, Reisenauer M, Aksenov I, Nguyen G, Johnston R, Rubin M, Kiss R, Mathieu V, Lefranc F, Correa J, Cavazos D, Brenner A, Rogelj S, Kornienko A, Frolova L. Activity of 2-Aryl-2-(3-indolyl)acetohydroxamates Against Drug-Resistant Cancer Cells. Journal of Medicinal Chemistry. Accepted February 13th, 2015. Aleksandra Gruslova, David A Cavazos, Jessica R. Miller, Eyal Breitbart, Yael C Cohen, Livnat Bangio, Niva Yakov, Anu Soundararajan, John R. Floyd, Andrew J. Brenner. VB-111: A novel anti-vascular therapeutic for glioblastoma multiforme. Journal of Neuro-Oncology. Accepted June 14th, 2015 Cavazos DA, Brenner AJ. Hypoxia in Astrocytic Tumors and Implications for Therapy. Neurobiology of Disease. Accepted June 12th, 2015 Faris R, Weber MM, Seeger DR, Cavazos D, de Graffenried L, Murphy EJ, Jolly CA. Mitochondrial Glycerol-3-Phosphate Acyltransferase-Dependent Phospholipid Synthesis Modulates Phospholipid Mass and IL-2 Production in Jurkat T Cells.Lipids. 2016 Mar;51(3):291-301. doi: 10.1007/s11745-016-4121-5. Epub 2016 Jan 21. PMID: 26797755 Sareddy Gangadhara R, Xiaonan Li, Jinyou Liu, Lauren Garcia, Suryavathi Viswanadhapalli, Aleksandra Gruslova, David Cavazos, Michael Garcia, Anders Storm, Jan-Ake Gustafsson, Tekmal Rajeshwar Rao, Andrew Brenner, and Ratna Vadlamudi. Selective Estrogen Receptor β Agonist LY500307 as a Novel Therapeutic Agent for Glioblastoma. Scientific Reports. Accepted March 21st, 2016. Xiaojie Yu, Yiqiang Zhang, David Cavazos, Xiuye Ma, Zhenze Zhao, Liqin Du and Alexander Pertsemlidis. miR-195 targets cyclin D3 and survivin to modulate cell cycle progression, apoptosis, senescence, migration and invasion of non-small cell lung cancer. Cell Death and Disease. Manuscript In Press 11/2017. Paper #CDDIS-17-1487-T Andrew Brenner, Richard Zuniga, Jessica D. Sun, John Floyd, Charles P. Hart, Stew Kroll, Lisa Fichtel, David Cavazos, Laura Caflisch, Aleksandra Gruslova, Shiliang Huang, Yichu Liu, Alessia Lodi, and Stefano Tiziani. Hypoxia-activated evofosfamide for treatment of recurrent bevacizumab-refractory glioblastoma: a phase I surgical study. Neuro-Oncology, 20(9), 1231-1239. Doi:10.1093/neuonc/noy015. Feb. 2018.

Alison Clark Arakane Y, Baguinon MC, Jasrapuria S, Chaudari S, Doyungan A, Kramer KJ, Muthukrishnan S, and Beeman RW. (2011) Both UDP Nacetylglucosamine pyrophosphorylases of Tribolium castaneum are critical for molting, survival and fecundity. Insect Biochem Mol Biol, 41:42-50. PMID: 20920581. Turunen M, Spaeth JM, Keskitalo S, Park MJ, Kivioja T, Clark AD, Mäkinen N, Vähärautio A, Aavikko M, Kämpjärvi K, Nurkkala H, Vahteristo P, Kim CA, Aaltonen LA, Varjosalo M, Taipale J, and Boyer TG. (2014) Uterine leiomyoma-linked MED12 mutations disrupt Mediator associated CDK activity. Cell Rep, 7: 654–660. PMCID: PMC4041330 Kämpjärvi K, Park MJ, Mehine M, Kim NH, Clark AD, Bützow R, Böhling T, Böhm J, Mecklin JP, Järvinen H, Tomlinson IPM, van der Spuy ZM, Sjöberg J, Aaltonen LA, Boyer TG, and Vahteristo P. (2014) MED12 exon 1 mutations in uterine leiomyomas. Hum Mutat, 35(9):1136-41. PMID:24980722. Clark AD*, Oldenbroek M* and Boyer TG. (2015) Mediator kinase module and human tumorigenesis. Crit Rev Biochem Mol Biol, 6: 1-34. PMID: 26182352 * co-first author Kämpjärvi K, Kim NH, Keskitalo S, Clark AD, von Nandelstadh P, Turunen M, Heikkinen T, Park MJ, Mäkinen N, Kivinummi K, Lintula S, Hotakainen K, Nevanlinna H, Hokland P, Böhling T, Bützow R, Böhm J, Mecklin JP, Järvinen H, Porkka K, Visakorpi T, Taipale J, Varjosalo M, Boyer TG, and Vahteristo P. (2016) Somatic MED12 mutations in prostate cancer and uterine leiomyomas promote tumorigenesis through distinct mechanisms. Prostate, 76(1) :22-31. PMID: 26383637 Clark AD, Oldenbroek M, Wang, Y, Spaeth JM, Gao, F, Jin VX, Boyer TG. (2019) Mediator kinase modulates oncogenic WNT/β-Catenin signaling through regulation of super-enhancer function. Manuscript in preparation.

Leigh Feuerbacher Beyene, T.J., L.A. Feuerbacher, T.G. Nagaraja, T.J. Spore, D.A. Blasi, N. Cernicchiaro. 2019. Antimicrobial resistance in gut bacteria of stocker cattle administered with prophylactic and therapeutic antimicrobials. In preparation. Wang, G., L.A. Feuerbacher, P.R. Hardwidge. 2018. Influence of intestinal microbiota transplantation and NleH expression on Citrobacter rodentium colonization of mice. Pathogens doi:10.3390/pathogens7020035. Gao, X., T.H. Pham, L.A. Feuerbacher, K. Chen, M.P. Hays, G. Singh, C. Rueter, R. Hurtado-Guerrero, and P.R. Hardwidge. 2016. Citrobacter rodentium NleB protein inhibits tumor necrosis factor (TNF) receptor-associated factor 3 (TRAF3) ubiquitination to reduce host type I interferon production. Journal of Biological Chemistry. 291: 18232-18238. Martinez-Quiles, N., L.A. Feuerbacher, M. Benito-León, and P.R. Hardwidge. 2014. Contribution of Crk adaptor proteins to host cell and bacteria interactions. BioMed Research International. Vol. 2014, Article ID 37290, doi:10.1155/2014/372901.

Feuerbacher, L.A. and P.R. Hardwidge. 2014. Influence of NleH effector expression, host genetics, and inflammation on Citrobacter rodentium colonization of mice. Microbes and Infection. 16: 429-433. Childress, C., L.A. Feuerbacher, L. Phillips, A. Burgum, and D. Kolodrubetz. 2013. Mlc is a transcriptional activator with a key role in integrating cyclic AMP receptor protein and integration host factor regulation of leukotoxin RNA synthesis in Aggregatibacter actinomycetemcomitans. Journal of Bacteriology. 195: 2284-97. Gao, X., X. Wang, T. Pham, L.A. Feuerbacher, M.L. Lubos, M. Huang, R. Olsen, A. Mushegian, C. Slawson, and P.R. Hardwidge. 2013. A bacterial effector with glycosyltransferase activity targets GAPDH function in innate immunity. Cell Host & Microbe. 13: 87-99. Feuerbacher, L.A., A. Burgum, and D. Kolodrubetz. 2011. The cyclic-AMP receptor protein (CRP) regulon in Aggregatibacter actinomycetemcomitans includes leukotoxin. Microbial Pathogenesis. 51:133-41.

Dustin Green Green, D. P., Limjunyawong, N., Gour, N., Pundir, P., & Dong, X. (2019). A Mast-Cell-Specific Receptor Mediates Neurogenic Inflammation and Pain. Neuron. https://doi.org/10.1016/j.neuron.2019.01.012

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Green, D. P., & Dong, X. (2015). Supporting itch: a new role for astrocytes in chronic itch. Nature Medicine, 21(8), 841–2. PMID: 26248264

Green, D. P., & Dong, X. (2016). The cell biology of acute itch. Journal of Cell Biology, 25;213(2):155-61. PMID: 27114499 Green, D. P., et al. (2016). Central activation of TRPV1 and TRPA1 by novel endogenous agonists contributes to mechanical allodynia and thermal hyperalgesia after burn injury. Molecular Pain, 12:1–9. PMID: 27411353

Green, D. P., & Dong, X. (2015). Supporting itch: a new role for astrocytes in chronic itch. Nature Medicine, 21(8), 841–2. PMID: 26248264

Eskander, M. A., Ruparel, S., Green, D. P., Chen, P. B., Por, E. D., Jeske, N. A., … Hargreaves, K. M. (2015)Persistent Nociception Triggered by Nerve Growth Factor (NGF) Is Mediated by TRPV1 and Oxidative Mechanisms. The Journal of Neuroscience 35(22), 8593–603. PMID: 26041925 Ruparel, S., Bendele, M., Wallace, A., & Green, D.P. (2015). Released lipids regulate transient receptor potential channel (TRP)-dependent oral cancer pain. Mol Pain, 11(1), 30. PMID: 26007300

Green, D. P., Ruparel, S., Roman, L., Henry, M. A. & Hargreaves, K. M. (2013) Role of endogenous TRPV1 agonists in a postburn pain model of partial-thickness injury. Pain 154, 2512-2520. PMID: 23891895

Patil, M. J., Green, D. P., Henry, M. A. & Akopian, A. N. (2013) Sex-dependent roles of prolactin and prolactin receptor in postoperative pain and hyperalgesia in mice. Neuroscience 253C, 132-141. PMID: 23994182

Ruparel, S., Green, D. P., Chen, P. & Hargreaves, K. M. (2012) The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain. Molecular Pain 8, 73. PMID: 23006841

Heather Hambright Hambright HG, Hurez V, Curiel TJ. Chronic Mechanistic Target of Rapamycin Inhibition: Preventing Cancer to Delay Aging or Vice Versa? M. Extermann (Ed.), Geriatric Oncology. New York, NY. Springer Publishing, Jan 2018. DOI 10.1007/978-3-319-44870-1_81-1. Hambright HG, Kumar AP, Ghosh R. Mitochondrial superoxide inhibits autophagy and induces apoptosis through SQSTM1-mediated mechanism. American Association for Cancer Research Annual Meeting, Apr 2017. Published in: Cancer Research 77(13 Supplement):5466-5466, July 2017. Hambright HG, Ghosh R. Autophagy: In the cROSshairs of cancer. Biochem Pharmacol. Oct 2016. PMCID: PMC5322764.

Hambright HG, Meng P, Kumar AP, Ghosh R. Inhibition of PI3K/AKT/mTOR axis disrupts oxidative stress-mediated survival of melanoma cells. Oncotarget. 6(9): 7195-208, Mar 2015. PMCID: PMC4466678. Hambright HG, Batth IS, Xie J, Ghosh R, Kumar AP. Palmatine inhibits growth and invasion in prostate cancer cells: potential role for rpS6/NFκB/FLIP. Molecular Carcinogenesis. 54(10): 1227-34. Oct 2015. PMCID: PMC4490121. Kumar AP, Graham H, Robson C, Garapati K, Ghosh R. An Overview of Anticancer Herbal Medicines. Evidence-Based Anticancer Complementary and Alternative Medicine. Ed. William C.S. Cho. New York: Springer, 2011. 1-36. (Book chapter) Kumar AP, Graham H, Robson C, Thompson IM, Ghosh R. Natural products: potential for developing Phellodendron amurense bark extract for prostate cancer management. Mini Rev Med Chem. 10(5):388-97, May 2010. PMID: 20370708.

Ghosh R, Graham H, Rivas P, Tan XJ, Crosby K, Bhaskaran S, Schoolfield J, Banu J, Fernandes G, Yeh IT, Kumar AP. Phellodendron amurense bark extract prevents progression of prostate tumors in transgenic adenocarcinoma of mouse prostate: potential for prostate cancer management. Anticancer Research. 30(3): 857-65, Mar 2010. PMID: 20393007.

Rachel Hartley Soto C, Du H-C, Fox R, Yang T, Hooson J, Hartley R, Zhang G, Anastasio N, Gilbertson S, Cunningham K. In Vivo and In Vitro Analyses of Novel Peptidomimetic Disruptors for the

Serotonin 5-HT2C Receptor Interaction with Phosphatase and Tensin Homolog (PTEN). Submitted to ACS Chemical Biology 13 January 2019. Wild CT, Miszkiel JM, Wold EA, Soto CA, Ding C, Hartley RM, White MA, Anastasio NC, Cunningham KA, Zhou J. Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-Carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT2C Receptor. J Med Chem. 2019;62(1):288-305. PMID:29620897 Chen YC, Hartley RM, Anastasio NC, Cunningham KA, Gilbertson SR. Synthesis and Structure-Activity Relationships of Tool Compounds Based on WAY163909, a 5-HT2C Receptor Agonist. ACS Chem Neurosci. 2017 May 17;8(5):1004-1010. PMID:28414422 Shaffer CV, Cai S, Peng J, Robles AJ, Hartley RM, Powelll DR, Du L, Cichewicz RH, Mooberry SL. Texas native plants yield compounds with cytotoxic activities against prostate cancer cells. J Nat Prod. 2016 Mar 25;79(3):531-40. PMID:26785306 Robles AJ, Peng J, Hartley RM, Lee B, Mooberry SL. Melampodium leucanthum, a Source of Cytotoxic Sesquiterpenes with Antimitotic Activities. J Nat Prod. 2015 Mar 27;78(3):388-95. PMID:25685941 Peng J, Hartley RM, Fest GA, Mooberry SL. Amyrisins A-C, O-Prenylated Flavonoids from Amyris madrensis. J Nat Prod. 2012 Mar 23;75(3):494-6. PMID:22260294 Hartley RM, Peng J, Fest GA, Dakshanamurthy S, Frantz DE, Brown ML, Mooberry SL. Polygamain, a New Microtubule Depolymerizing Agent that Occupies a Unique Pharmacophore in the Colchicine Site. Mol Pharmacol. 2012 Mar;81(3):431-9. PMID:22169850 Babu, B, Lee M, Lee L, Strobel R, Brockway O, Nickols A, Sjoholm R, Tzou S, Chavda S, Desta D, Fraley G, Siegfried A, Pennington W, Hartley RM, Westbrook C, Mooberry SL, Kiakos K, Hartley JA, Lee M. Bioorg Med Chem. 2011 Apr 1; 19(7). Lee M, Brockway O, Dandavati A, Tzou S, Sjoholm R, Nickols A, Babu B, Chavda S, Satam V, Hartley RM, Westbrook C, Mooberry SL, Fraley G, Lee M. Bioorg Med Chem Lett. 2011 Apr 1; 21(7):2087-91.

Blaine Jacobs Blaine A. Jacobs, Teresa A. Chavera, William P. Clarke, and Kelly A. Berg (2018) Allosterism within delta opioid receptor – kappa opioid receptor (DOR-KOR) heteromers in peripheral nociceptors: regulation of agonist efficacy. Mol Pharmacol, 93(4):376-386. PMID: 29436492 Burgos-Vega CC, Quigley LD, Trevisan Dos Santos G, Yan F, Asiedu M, Jacobs B, Motina M, Safdar N, Yousuf H, Avona A, Price TJ, Dussor G (2018) Non-invasive Dural stimulation in mice: A novel preclinical model of migraine. Cephalalgia, [Epub ahead of print]. PMID:29848109 Blaine A. Jacobs, Miryam M. Pando, Elaine M. Jennings, Raehannah J. Jamshidi, Joshua C. Zamora, Teresa S. Chavera, William P. Clarke and Kelly A. Berg (2018) Signaling characteristics and functional regulation of delta opioid-kappa opioid receptor (DOR-KOR) heteromers in peripheral sensory neurons. Neuropharmacology, accepted with revisions.

Kurt Kuhne Greene W, Kuhne K, Ye F, Chen J, Zhou F, Lei X, Gao SJ. 2007. Molecular biology of KSHV in relation to AIDS-associated oncogenesis. Cancer Treat Res; 133: 69-127. (PMCID: PMC2798888) Xie J, Ajibade AO, Ye F, Kuhne K, Gao SJ. 2008. Reactivation of Kaposi's sarcoma-associated herpesvirus from latency requires MEK/ERK, JNK and p38 multiple mitogen-activated protein kinase pathways. Virology; 371(1): 139-54. (PMCID: PMC2239004) Ye FC, Zhou FC, Xie JP, Kang T, Greene W, Kuhne K, Lei XF, Li QH, Gao SJ. 2008. Kaposi's sarcoma-associated herpesvirus latent gene vFLIP inhibits viral lytic replication through NF-kappaB-mediated suppression of the AP-1 pathway: a novel mechanism of virus control of latency. J Virol; 82(9): 4235-49. (PMCID: PMC2293065) Chen J, Ye F, Xie J, Kuhne K, Gao SJ. 2009. Genome-wide identification of binding sites for Kaposi's sarcoma-associated herpesvirus lytic switch protein, RTA. Virology; 386 (2):290-302. (PMCID: PMC2663009) Kuhne K, Luo RX, Gao SJ. 2012. KLIP1 associates with Mad3 of the Myc-Max-Mad transcription regulatory network. (In Review) Kuhne K, Luo RX, Jones TN, Gao SJ. 2012. A novel mechanism for regulation of c-Myc: the centromeric protein, KLIP1, recruits the c-Myc oncogene to centromeric heterochromatin and functionally antagonizes c-Myc-driven transcriptional activation and cell proliferation. (In Review)

Rebecca Lane Guo, H., Gilley, R.P., Fisher, A., Lane, R., Landsteiner, V.J., Ragan, K.B., Dovey, C.M., Carette, J.E., Upton, J.W., Mocarski, E.S., and Kaiser, W.J. Species-Independent Contribution of ZBP1/DAI/DLM-1-Triggered Necroptosis in Host Defense Against HSV1. Cell Death Dis 9(8):816 (2018). PMCID: PMC6062522 Lane, R.K., Guo, H., Fisher, A., Diep, J., Lai, Z., Chen, Y., Carette, J. and Kaiser, W. Genome- wide CRISPR knockout screen identifies Neuropilin-1 as an entry factor for murine cytomegalovirus. In preparation. Lane, R.K., Borror, M.B., Radetskaya, O., Garrett, A., Friedman, T., Russel, J., Kaeberlein, M., and Rea, S.L. PMK-3/p38 Mitochondrial Retrograde Response Functions via Intestinal Cells and the ESCRT Machinery to Extend Life. In Preparation.

Elaine Por McDaniel JS, Holt AW, Por ED, Eriksson E, Johnson AJ, Griffith GL. The utilization of an ocular wound chamber on corneal epithelial wounds. (2018) Clinical Ophthalmology (12)903-911. Por ED, Sandoval ML, Thomas-Benson C, Burke TA, Doyle Brackley A, Jeske NA, Cleland JM, Lund BJ. Repeat low-level blast exposure increases transient receptor potential vanilloid 1 (TRPV1) and endothelin-1 (ET-1) expression in the trigeminal ganglion. (2017) PLOS One 12(8):e0182102.

Greene WA, Burke WA, Kaini RR, Por ED, Wang HC. Polarized secretion of matrix metalloproteinases and their inhibitors by retinal pigmented epithelium derived from induced pluripotent stem cells during wound healing. (2016) In press. Greene WA, Burke TA, Por ED, Kaini RR, Wang HC. Secretion profile of induced pluripotent stem cell-derived retinal pigmented epithelium during wound healing. (2016) Investigative Ophthalmology and Visual Science 57(10):4428-4441. Por ED, Greene WA, Burke TA, Wang HC. Trichostatin A inhibits retinal pigmented epithelium activation in an in vivo model of proliferative vitreoretinopathy. (2016) Journal of Ocular Pharmacology and Therapeutics 32(7):415-424. Por ED, Choi JH, Lund BJ. Low-level blast exposure increases transient receptor potential vanilloid 1 (TRPV1) expression in the rat cornea. (2016) Current Eye Research 41(10):1294-1301. Eskander MA, Ruparel S, Green DP, Chen PB, Por ED, Jeske NA, Gao X, Flores ER, Akopian, AN, Hargreaves KM. Persistent nociception triggered by nerve growth factor (NGF) is mediated by TRPV1 and oxidative mechanisms. (2015) Journal of Neuroscience 35(22):8593-603. Rowan MP, Bierbower SM, Eskander MA, Szteyn, K, Por ED, Gomez R, Veldhuis N, Bunnett NW, Jeske NA. Activation of Mu opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) via b-arrestin-2-mediated cross-talk. (2014) PLoS ONE 9(4):e93688. Por ED, Gomez R, Akopian AN, Jeske NA. Phosphorylation regulates TRPV1 and b-arrestin-2 association. (2013) Biochemical Journal 451(1):101-9. Por ED, Bierbower SM, Berg KA, Gomez R, Akopian AN, Wetsel WC, Jeske NA. b-arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel. (2012) Journal of Biological Chemistry 287(44):37522-63. Choi YK, Por ED, Kwon YG, Kim YM. Regulation of ROS production and vascular function by carbon monoxide. Oxidative Medicine and Cellular Longevity, vol 2012, Article ID 794237, 17 pages. doi:10.1155/2012/794237. Jeske NA, Por ED, Belguin S, Chadhury S, Berg KA, Akopian AN, Henry MA, Gomez R. AKAP150 mediates TRPV1 sensitivity to phosphatidylinositol-4,5-bisphosphate. (2011) Journal of Neuroscience 31(23):8681-8. Gomez R, Por ED, Berg KA, Clarke WP, Glucksman MJ, Jeske NA. Metallopeptidase inhibition potentiates bradykinin-induced hyperalgesia. (2011) Pain 152(7)1548-54. Por ED, Samelson BK, Belguin S, Akopian AN, Scott JD, Jeske NA. PP2B/Calcineurin-mediated desensitization does not require AKAP150. (2010) Biochemical Journal. 432(3):549-56. Por E, Byun HJ, Lee EJ, Lim LH, Jung SY, Park I, Kim YM, Jeoung DI, Lee H. The cancer/testis antigen CAGE with oncogenic potential stimulates cell proliferation by upregulating cyclins D1 and E in an AP-1 and E2F-dependent manner. (2010) Journal of Biological Chemistry. 285(19)14475-85. Oh HY, Namkoong, SJ, Lee SJ, Por E, Kim CK, Billar TR, Han JA, Ha KS, Chung HT, Kwon

YG, Lee H, Kim YM. Dexamethasone protects primary cultured hepatocytes from death receptor-mediated apoptosis by upregulation of cFLIP. (2006) Cell Death and Differentiation. 13 (3):512-23.

Margaux Salas Salas M, Hargreaves KM, Akopian AN, 2009. TRPA1-mediated responses in trigeminal sensory neurons: interaction between TRPA1 and TRPV1. European Journal of Neuroscience; 29:1568-1578. (PMCID-PMC2765106) Patil M, Patwardhan A, Salas M. M., Hargreaves KM, Akopian A. 2011. Cannabinoid receptor antagonists AM251 and AM630 activate TRPA1 in sensory neurons. Neuropharmacology; 61:778-88. (PMCID: PMC3130079) Loyd D. R., Sun X. X., Locke E. E., Salas M. M., Hargreaves K. M. 2012. Sex differences in serotonin enhancement of capsaicin-evoked calcitonin gene-related peptide release from human dental pulp. Pain, 153(10) 2061-70 (PMCID: 3461945) Clifford JL, Fowler M, Hansen JJ, Cheppudira B, Nyland JE, Salas M.M., McGhee LL, Petz LN, and Loyd DR. 2014. State of the Science Review: Advances in pain management in wounded service members over a decade of war. Journal of Trauma Acute Care Surgery, 77(3 Suppl 2) S228-236 Pujol, L. A., Sussman, L., Clapp, J., Nilson, R., Gill, H., Boge, J., . . . Goff, B. 2015. Functional Restoration for Chronic Pain Patients in the Military: Early Results of the San Antonio Military Medical Center Functional Restoration Program. US Army Med Dep J, 1-7. Salas, M. M., McIntyre, M. K., Petz, L. N., Korz, W., Wong, D., & Clifford, J. L. 2015. Tetrodotoxin suppresses thermal hyperalgesia and mechanical allodynia in a rat full thickness thermal injury pain model. Neurosci Lett, 607, 108-113. Benov, A., Salas, M. M., Nakar, H., Antebi, B., Tarif, B., Yitzhak, A., & Glassberg, E. 2017. Battlefield pain management: A view of 17 years in Israel Defense Forces. J Trauma Acute Care Surg, 83(1 Suppl 1), S150-S155. Salas, M. M., Clifford, J. L., Hayden, J. R., Iadarola, M. J., & Averitt, D. L. 2017. Local Resiniferatoxin Induces Long-Lasting Analgesia in a Rat Model of Full Thickness Thermal Injury. Pain Med, 18(12), 2453-2465. (PMCID: 6279302)

Olivia Tran Tran, Olivia N., et al. "Stem Cell–Based Restoration of Salivary Gland Function." A Roadmap to Non-Hematopoietic Stem Cell-based Therapeutics. Academic Press, 2019. 345-366.”

Post-Doc Fellows Dayna Loyd Loyd, DR, Wang, X, Murphy, AZ. 2008. Sex differences in µ-opioid receptor expression in the rat midbrain periaqueductal gray are essential for eliciting sex differences in morphine analgesia. J. Neuroscience; 28(52):14007-17. (PMCID: PMC2819468) Loyd, DR, Murphy, AZ. 2009. The role of the periaqueductal gray in the modulation of pain in females: Is the anatomy and physiology really that different? Review Article in a Special Issue on The Periaqueductal Gray. Neural Plasticity, Volume 2009, Article 46289, 12 pages, doi: 10.1155/2009/46289. (PMCID: PMC2633449) Loyd, DR, Weiss, G, Henry, MA, Hargreaves, KM. 2011. Serotonin Increases the Functional Activity of Capsaicin-Sensitive Rat Trigeminal Nociceptors via Peripheral Serotonin Receptors. PAIN, 152(10): 2267-76. (PMCID: PMC3183408) Loyd, DR, Chen, PB, Hargreaves, KM. 2012. Antihyperalgesic effects of anti-serotonergic compounds on serotonin- and capsaicin-evoked thermal hyperalgesia in the rat. Neuroscience; 203: 207-15. (PMID: 22209919) Loyd, DR, Sun, XX, Locke, E, Salas, MM, Henry, MA, Hargreaves, KM. 2012. Sex Differences in Serotonin Enhancement of Capsaicin-evoked Calcitonin Gene-Related Peptide Release from Human Dental Pulp. PAIN; Jul 19. (PMID: 22819536) Loyd, D.R., Henry, M.A. and Hargreaves, K.M. (2013) Serotonergic Neuromodulation of Peripheral Nociceptors. Invited Review in a Special Issue on Signal Processing in Peripheral Sensory Organs. Seminars in Cell and Developmental Biology, 24: 51-57. Cheppudira, B.P., Greer, A., Mares, A., Fowler, M., McGhee, L., Devore, D., Petz, L., Loyd, D.R., Clifford, J.L. (2013) Curcumin: A Novel Therapeutic for Burn Pain and Wound Healing. Expert Opinion on Investigational Drugs, 22(10): 1295-303. Fowler, M., Clifford, J.L., Garza, T.H., Slater, T.M., Arizpe, H.M., Novak, J., Petz, L.M. and Loyd, D.R. (2014) A rat model of full thickness thermal injury characterized by thermal hyperalgesia, mechanical allodynia, pronociceptive peptide release and tramadol analgesia. Burns, 40(4): 759-771. Loyd, D.R. and Murphy, A.Z. (2014) The Neuroanatomy of Sexual Dimorphism in Opioid Analgesia. Invited Review in a Special Issue on The Importance of Sex in the Etiology, Presentation, and Treatment of Neurological Disorders. Experimental Neurology, 259C: 57-63. Clifford, J.L., Fowler, M., Hansen, J.J., Cheppudira, B.P., Nyland, J.E., Salas, M.M., McGhee, L.L., Petz, L.N., Loyd, D.R. (2014) State of the Science Review: Advances in pain management in wounded service members over a decade at war. Journal of Trauma and Acute Care Surgery, 77(3 Suppl 2): S228-236. Clifford, J.L., Mares, A., Hansen, J., Averitt, D.L. (2015) Preemptive perineural bupivacaine attenuates the maintenance of mechanical and cold allodynia in a rat spinal nerve ligation model. BMC Anesthesiology, 15: 135.

Nyland, J.E Nyland, J.E., McLean, S.A., Averitt, D.L. (2015) Prior stress exposure increases pain behaviors in a rat model of full thickness thermal injury. Burns, 41(8): 1796-1804. Salas, M.M., Clifford, J.L., Hayden, J.R., Iadarola, M.J., Averitt, D.L. (2017) Local resiniferatoxin induces long-lasting analgesia in a rat model of full thickness thermal injury. Pain Medicine, 18(12): 2453-2465. Kaur, S., Benton, W.L., Tongkhuya, S.A., Lopez, C.M.C., Uphouse, L., Averitt. D.L. (2018) Sex differences and estrous cycle effects of peripheral serotonin-evoked rodent pain behaviors. Neuroscience, 384: 87-100. Averitt, D.L., Eidson, L.N., Doyle, H.H., and Murphy, A.Z. (2019) Neuronal and Glial Factors Contributing to Sex Differences in Opioid Modulation of Pain. Invited Review in Neuropsychopharmacology, 44(1): 155-165.

Stella Bernardo Bernardo, SM, Gray, KA, Todd, RB, Cheetham, BF, and Katz, ME. 2007. Characterization of regulatory non-catalytic hexokinases in Aspergillus nidulans, Molecular Genetics and Genomics; 277(5): 519-532. (PMID: 17226029) Westbrook, SD, Kirkpatrick, WR, Freytes, CO, Toro, JJ, Bernardo, SM, Patterson, TF, Redding, SW, Lee, SA. 2007. Candida krusei sepsis secondary to oral colonization in a hemopoietic stem cell transplant recipient, Medical Mycology; 45(2): 187-190. (PMID: 17365656) Lee, SA, Jones, J, Khalique, Z, Kot, J, Alba, M, Bernardo, SM, Seghal, A, Wong, B. 2007. A functional analysis of the Candida albicans homolog of Saccharomyces cerevisiae VPS4, FEMS Yeast Research; 7(6): 973-985. (PMID: 17506830) Bernardo SM, Khalique Z, Kot J, Jones JK., Lee SA. 2008. Candida albicans VPS1 contributes to protease secretion, filamentation, and biofilm formation, Fungal Genetics and Biology; 45(6): 861-877. (PMCID: PMC2729247) Katz, ME, Bernardo SM, Cheetham, BF. 2008. The interaction of induction, repression and starvation in the regulation of extracellular proteases in Aspergillus nidulans: evidence for a role for CreA in the response to carbon starvation, Current Genetics; 54(1): 47-55. (PMID: 18512059) Lee,SA, Jones, J, Hardison, S, Kot, J, Khalique, Z, Bernardo, SM, Lazzell, A, Monteagudo, C, and Lopez-Ribot, J. 2009. Candida albicans VPS4 is required for secretion of aspartyl proteases and in vivo virulence, Mycopathologia; 167(2): 55-63. (PMID: 18814053) Miceli, MH, Bernardo, SM, Lee, SA. 2009. In vitro analyses of the combination of high dose doxycycline and antifungal agents against Candida albicans biofilms, Int J Antimicrob Agents; 34(4):326-332. (PMID: 19515537) Miceli MH, Bernardo SM, Lee SA. 2009. In vitro analysis of the occurrence of a paradoxical effect with different echinocandins and Candida albicans biofilms, Int J Antimicrob Agents; 34:500-502. (PMID: 19674873)

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DuPont, B.R, Linn, R., Knight, C.B, Plaetke, R, and Leach, R.J. Reassignment of the 92-kDa Type I Collagenase Gene (CLG4) to Human Chromosome 20. Cytogenetics and Cell Genetics 72:159-60, 1996. PMID: 8978762 DuPont, B.R., Linn, R., Knight, C.B., Roodman, G.D., Sakaguchi, A.Y, Lalley, P.A., Fournier, R.E.K., and Leach, R.J. Assignment of Matrix Metalloproteinase 9 (Mmp9) to Mouse Chromosome 2 bands H1 and H2. Cytogenetics and Cell Genetics 74:118-119, 1996. PMID: 8893816 MacDougall, M., Jeffords, L., Gu, T.T., Knight, C.B., Frei, G., Reus, B.E., Otterud, B., Leppert, M., and Leach, R.J. Genetic Linkage of the Dentinogenesis Imperfecta Type III Locus to Chromosome 4q. J Dental Research 78(6):1277-1282, 1999. PMID: 10371253 MacDougall, M., Simmons, D., Knight, C.B., Dodds, A., Zeichner-David, M., Hu, C.C., et al., Cloning and Characterization of Mouse Tuftelin cDNA. J Dental Research. 77(12):1970-1978, 1998. PMID: 9839784 Gonzales, C.B.*, Kirma, N.B., De La Chapa, J.J., Chen, R., Henry, M.A., Luo, S., and Hargreaves, M. (*Corresponding author). Vanilloids Induce Oral Cancer Apoptosis Independent of TRPV1. Oral Oncology 50(5):437-447, 2014. PMID: 24434067 Dasari, R., De Carvalho, A., Medellin, D.C., Middleton, K.N., Volmar, M.N.M., Frolova, L.V., Mathieu, V., Rogelj, S., Gonzales, C.B., Calixto, Evidente, A., Gautier, M., Munirathinam, G J.B., Glass, Burth, P R., Pelly, S.C., van Otterlo, W.A.L., Kiss, R., Hague, F., Rossato, M.F., De La Chapa, J.J., Dybdal-hargreaves, N.F., Pillai, A., and Kornienko, A. Synthetic and Biological Studies of Sesquiterpene Polygodial: Activity of 9-Epipolygodial Against Drug Resistant Cancer Cells. Chem Med Chem Dec;10(12):2014-26, 2015. PMID: 26360047 Dasari, R., De Carvalho, A., Medellin, D.C., Middleton, K.N., Hague, F., Volmar, M.N.M., Frolova, L.V., Rossato, M.F., De La Chapa, J.J., Dybdal-hargreaves, N.F., Pillai, A., Mathieu, V., Rogelj, S., Gonzales, C.B., Calixto, J.B., Evidente, A., Gautier, M., Munirathinam, G., Glass, R., Burth, P., Pelly, S.C., van Otterlo, W.A.L., Kiss, R., and Kornienko, A. Wittig Derivatization of Sesquiterpenoid Polygodial Leads to Cytostatic Agents with Activity Against Drug Resistant Cancer Cells and Capable of Pyrrolylation of Primary Amines. European J of Medicinal Chemistry 103:226-237, 2015. PMID: 2636004

Connonier, S.A., Gonzales, C.B., Ely, K., Guelcher, S.A., and Sterling, J.A. Hedgehog and TGFβ signaling converge on Gli2 to control bony invasion and bone destruction in Oral Squamous Cell Carcinoma. Oncotarget 7(46):76062-075, 2016. PMID: 27738315 Gonzales, C. B.*, Hargreaves, N.F., De La Chapa, J. J., Chen, R., Parra, J., and Kirma, NB. (*Corresponding author). Co-Targeting ALK and EGFR Parallel Signaling in Oral Squamous Cell Carcinoma. Oral Oncology Aug;59:12-9, 2016. PMID: 27424178 De La Chapa, J., Singha, P.K., Sallaway, M., Self, K., Nasreldin, R., Dasari, R., Hart, M., Kornienko, A., Just, J., Smith, J., Bissember, A.C., and Gonzales, C.B.* (*Corresponding author). Novel Polygodial Analogs P3 and P27: Efficacious Therapeutic Agents Disrupting Mitochondrial Function in Oral Squamous Cell Carcinoma. International J of Oncology, 53(6):2627-2636, 2018. PMID: 30320372. De La Chapa, J., Singha, P.K., Lee, D.R., and Gonzales, C.B.* (*Corresponding author). Thymol Inhibits Oral Squamous Cell Carcinoma Growth via Mitochondria-Mediated Apoptosis. J of Oral Pathology and Medicine 47(7): 674-682, 2018. PMID: 29777637 De La Chapa, J., Valdez, M., Ruiz III, F., Gonzales, K., Mitchell, W., McHardy, S.F., Hart, M., Polusani, S.R., and Gonzales, C.B.* (*Corresponding author). Synthesis and SAR of Novel Capsazepine Analogs with Significant Anti-Cancer Effects in Multiple Cancer Types. Bioorganic and Medicinal Chemistry, 27(1):208-215; 2019. PMID: 30528162 De La Chapa, J., Singha, P.K., Self, K.K., Sallaway, M. L., McHardy, S.F., Hart, M., McGuff, H.S., Valdez, M., Ruiz III, F., Polusani, S.R., and Gonzales, C.B.* (*Corresponding author). The Novel Capsazepine Analog, CIDD-99, Significantly Inhibits Oral Squamous Cell Carcinoma In Vivo Through a TRPV1-Independent Induction of ER Stress, Mitochondrial Dysfunction, and Apoptosis. Journal of Oral Pathology and Medicine, provisionally accepted January 27, 2019.

Moraima Guadalupe Exome capture from saliva produces high quality genomic and metagenomic data. Kidd JM, Sharpton TJ, Bobo D, Norman PJ, Martin AR, Carpenter ML, Sikora M, Gignoux CR, Nemat-Gorgani N, Adams A, Guadalupe M, Guo X, Feng Q, Li Y, Liu X, Parham P, Hoal EG, Feldman MW, Pollard KS, Wall JD, Bustamante CD, Henn BM. BMC Genomics. 2014 Apr 4;15:262. Targeted genome enrichment for efficient purification of endosymbiont DNA from host DNA.; Geniez S, Foster JM, Kumar S, Moumen B, Leproust E, Hardy O, Guadalupe M, Thomas SJ, Boone B, Hendrickson C, Bouchon D, Grève P, Slatko BE.Symbiosis. 2012 Dec;58(1-3):201-207. Mitochondrial disease genetic diagnostics: optimized whole-exome analysis for all MitoCarta nuclear genes and the mitochondrial genome.Falk MJ, Pierce EA, Consugar M, Xie MH, Guadalupe M, Hardy O, Rappaport EF, Wallace DC, LeProust E, Gai X. Discov Med. 2012 Dec;14(79):389-99. Reactive oxygen species hydrogen peroxide mediates Kaposi's sarcoma-associated herpesvirus reactivation from latency.Ye F, Zhou F, Bedolla RG, Jones T, Lei X, Kang T,

Guadalupe M, Gao SJ.PLoS Pathog. 2011 May;7(5):e1002054. doi: 10.1371/journal.ppat.1002054. Epub 2011 May 19. The gut mucosal viral reservoir in HIV-infected patients is not the major source of rebound plasma viremia following interruption of highly active antiretroviral therapy.Lerner P, Guadalupe M, Donovan R, Hung J, Flamm J, Prindiville T, Sankaran-Walters S, Syvanen M, Wong JK, George MD, Dandekar S.J Virol. 2011 May;85(10):4772-82. doi: 10.1128/JVI.02409-10. Epub 2011 Feb 23. Risk factors influencing antibody responses to Kaposi's sarcoma-associated herpesvirus latent and lytic antigens in patients under antiretroviral therapy.Guadalupe M, Pollock BH, Westbrook S, Redding S, Bullock D, Anstead G, Agan BK, Marconi VC, Barbieri S, Sankar V, Rebeles J, Flahive Y, Schoolfield J, Wang L, Lei X, Dow D, Yeh CK, Dang H, Infante AJ, Gao SJ.J Acquir Immune Defic Syndr. 2011 Jan 1;56(1):83-90. doi: 10.1097/QAI.0b013e3181fdc928. Seroprevalence of Kaposi's sarcoma-associated herpesvirus and risk factors in Xinjiang, China.Fu B, Sun F, Li B, Yang L, Zeng Y, Sun X, Xu F, Rayner S, Guadalupe M, Gao SJ, Wang L.J Med Virol. 2009 Aug;81(8):1422-31. doi: 10.1002/jmv.21550. Rapid onset of intestinal epithelial barrier dysfunction in primary human immunodeficiency virus infection is driven by an imbalance between immune response and mucosal repair and regeneration.Sankaran S, George MD, Reay E, Guadalupe M, Flamm J, Prindiville T, Dandekar S. J Virol. 2008 Jan;82(1):538-45. Epub 2007 Oct 24. Viral suppression and immune restoration in the gastrointestinal mucosa of human immunodeficiency virus type 1-infected patients initiating therapy during primary or chronic infection.Guadalupe M, Sankaran S, George MD, Reay E, Verhoeven D, Shacklett BL, Flamm J, Wegelin J, Prindiville T, Dandekar S.J Virol. 2006 Aug;80(16):8236-47. E2F1 expression in LNCaP prostate cancer cells deregulates androgen dependent growth, suppresses differentiation, and enhances apoptosis.Libertini SJ, Tepper CG, Guadalupe M, Lu Y, Asmuth DM, Mudryj M.Prostate. 2006 Jan 1;66(1):70-81. Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressors. Sankaran S, Guadalupe M, Reay E, George MD, Flamm J, Prindiville T, Dandekar S. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9860-5. Epub 2005 Jun 24. Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral

therapy.Guadalupe M, Reay E, Sankaran S, Prindiville T, Flamm J, McNeil A, Dandekar S.J Virol. 2003 Nov;77(21):11708-17. Hepatitis C virus core protein expression leads to biphasic regulation of the p21 cdk inhibitor and modulation of hepatocyte cell cycle.Nguyen H, Mudryj M, Guadalupe M, Dandekar S.Virology. 2003 Jul 20;312(1):245-53. Simian immunodeficiency virus Nef protein delays the progression of CD4+ T cells through G1/S phase of the cell cycle.Ndolo T, Dhillon NK, Nguyen H, Guadalupe M, Mudryj M, Dandekar S. J Virol. 2002 Apr;76(8):3587-95. KSHV seroprevalence, and blood and saliva viral loads in the HIV-infected population of south Texas; Infectious Agents and Cancer; Guadalupe M, Flahive Y, Westbrook S, Redding S, Bullock D, Sankar V, Agan B, Barbieri S, Yeh C-K, Dang H, Gao S-J;, 4(Suppl 2):P20, 2009.

Asma Khan Dionne RA, Khan AA, Gordon SM. 2001. Analgesia and COX-2 inhibition. Clinical and Experimental Rheumatology; 19(6 Suppl 25):S63-70. (PMID: 11695255) Khan AA, Brahim JS, Rowan JS, Dionne RA. 2002. In Vivo Selectivity of a Selective Cyclooxygenase-2 Inhibitor in the Oral Surgery Model. Clinical Pharmacology and Therapeutics; 72(1):44-49. (PMID: 12152003) Khan AA, Iadarola MJ, Yang H-Y T, Karai L, Dionne RA. 2007. Expression of COX-1 and -2 in a clinical model of acute inflammation. J Pain; 8(4):349-54.(PMCID: PMC2766840) Khan AA, Owatz CB, Schindler WG, Schwartz SA, Keiser K, Hargreaves KM. 2007. Measurement of mechanical allodynia and local anesthetic efficacy in patients with irreversible pulpitis and acute periradicular periodontitis. J Endod; 33 (7): 796-9. (PMID: 17804314) Khan AA, McCreary B, Owatz CB, Schindler WG, Schwartz SA, Keiser K and Hargreaves KM. 2007. The development of a diagnostic instrument for the measurement of mechanical allodynia. J Endod; 33(6):663-6. (PMID: 17509402) Owatz CB, Khan AA, Schindler WG, Schwartz SA, Keiser K, Hargreaves KM. 2007. The incidence of mechanical allodynia in patients with irreversible pulpitis. J Endod;33(5):552-6. (PMID : 17437870) Khan AA, Sun X, Hargreaves KM. 2008. The effect of calcium hydroxide on pro-inflammatory cytokines and neuropeptides. J Endod;34: 1360-3 (PMID: 18928847) Khan AA, Diogenes A, Jeske NA, Henry MA, Akopian A, Hargreaves KM. 2008. Tumor necrosis factor α enhances the sensitivity of rat trigeminal neurons to capsaicin. Neuroscience; 155(2):503-9. (PMID: 18582539)

Lim PF, Maixner W, Khan AA. 2011. TMD and co-morbid pain conditions. JADA; 142: 1365-7. (PMID: 22130437) Lim PF, Maixner W, Khan AA. 2011. Widespread pain in temperomandibular disorders. Pain Management. 2011; 1:181-187 (PMID: 24646357) Zhong S, Zhang S, Bair E, Nares S, Khan AA. 2012. Differential expression of microRNAs in normal and inflamed pulps. J Endod; 38(6): 746. (PMID: 22959106) King W, Bair E, Duggan D, Maixner W, Khan AA. The relationship between resting arterial blood pressure and acute postoperative pain in endodontic patients. J Orofac Pain 2012;26:321-327. (PMID 23110272) Naqvi AR, Self-Fordham J, Khan AA, Nares S. MicroRNAs responsive to Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis LPS modulate expression of genes regulating innate immunity in human macrophages. Innate Immunity. Epub September 23rd, 2013. (PMID: 24062196) Pettiette MT, Zhong S, Moretti A, Khan AA. The effect of statins on calcification of the dental pulp. J Endod 2013;39:1119-1123. (PMID: 23953283) Chan L, Zhong S, Naqvi AR, Self-Fordham J, Nares S, Khan AA. microRNAs: Novel modulators of endodontic periapical pathology. J Endod. 2013;39:1498-1503 (PMID: 24238436) Richardson SL, Rivera ER, Phillips C, Khan AA. Access to Endodontic Care in North Carolina Public Health and Medicaid Settings. J Public Health Dentistry. Epub October 3, 2013 (PMID: 24117673) Lim PF, Maixner W, Khan AA. Persistent Pain following Endodontic Therapy. (PMID: 2453892) Flake NM, Gibbs JL, Diogenes A, Hargreaves KM, Khan AA. A standardized novel method to evaluate radiographic root changes following endodontic therapy in immature teeth. J Endod. 2014;40:46-50. (PMID: 24331990) Galicia J, Naqvi AR, Ko C, Nares S, Khan AA. miRNA181a Negatively Regulates Toll-Like Receptor Agonist-Induced Interleukin-8 Production in Human Dental Pulp Fibroblasts and Macrophages. Genes and Immunity. 2014;15:333-7 (PMID: 24848932) Read JK, Bowles WR, Khan AA, Lunos S, McClanahan S. Effect of Ibuprofen on Masking Endodontic Diagnosis: A Randomized Clinical Trial. J Endod. 2014;40:1058-62 (PMID: 25069908) Hosseini B, Wright R, Khan AA, Duggan D, Bencharit S. Effects of Antibiotics on Bone and Soft Tissue Healing Following Immediate Single-tooth Implant Placement into Sites with Apical Pathology. Journal of Oral Implantology. 2015 41(5):e202-11 (PMID: 25076118) Aminoshariae A and Khan AA. Acetaminophen; Old Drug, New Issues. J Endod 2015:41:588-93 (PMID: 25732401)

Applebaum E, Nackley AG, Bair E, Khan AA. Genetic Variants in Cyclooxygenase Contribute to Post-Treatment Pain among Endodontic Patients. J Endod 2015; 41:1214-1218 (PMID: 26081267) Ciszek, BP#, Khan AA#, Dang H, Slade GS, Smith S, Bair E, Maixner W, Zolnoun D, Nackley AG. MicroRNA Expression Profiles Differentiate Chronic Pain Condition Subtypes. Translational Research. 2015;166(6):706-720.e11 (PMID: 26166255) Galicia JC, Henson BR, Parker JS, Khan AA. Gene expression Profile of Pulpitis. Genes Immun. 2016;17: 239-43 PMID: 27052691 Naqvi SR, Zhong S, Dang H, Fordham JB, Nares S, Khan AA. Expression profiling of LPS responsive miRNA in Primary Human Macrophages. J Microb Biochem Technol 2016:8: 136-43 PMID: 27307950 Zhong S, Naqvi SR, Nares S, Bair E, Khan AA. Viral microRNAs Identified in Human Dental Pulp. J Endod 2017;43:84-89 Taggar TJ, Wu D, Khan AA. A randomized clinical trial comparing two ibuprofen formulations in patients with acute odontogenic pain. J Endod In press 2017 St Paul A, Phillips C, Lee J, Khan AA. Provider Perceptions of Treatment Options for Immature Permanent Teeth. J Endod; 2017; 43:910-15 Shah H, Hernandez P, Budin F, Chittajallu D, Vimort JB, Walters R, Mol A, Khan A, Paniagua B. Automatic quantification framework to detect cracks in teeth. SPIE Int Soc Opt Eng. 2018 Medical Imaging 2018;10578.

Duqum I, Barker S, Marshall E, Wang R, Preisser JS and Khan AA. The effect of single tooth implant restorations on the survival morbidity, pulp and periapical health of adjacent teeth- a chart review. Clinical Implant Dentistry and Related Research. 2018;20:479-482.

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Murray DH, Hahnel M, Lauer J, Avellaneda MJ, Brouilly N, Cezanne A, Morales-Nararrete H, Perini ED, Ferguson C, Lupas AN, Kalaidzidis Y, Parton RG, Grill SW, Zerial, M. 2016 An Endosomal Tether Undergoes an Entropic Collapse to Bring Vesicles Together. Nature; 537(7618), 107-111 (PMID: 27556945). Deyaert E, Leemans M, Singh RK, Gallardo R, Steyaert J, Kortholt A, Lauer J, and Versees W. 2019 Structure and Nucleotide-induced Conformational Dynamics of the Chlorobium tepidum Roco Protein. Biochem J; 476(1), 51-66 (PMID: 30538153). Valerie Lee K Ramalingam, R Alvarez, VA Lee. Utilization of extracellular membrane proteins for enhancement of biofilm formation of Acinetobacter baumannii. Future Microbiology, submitted. K Ramalingam, VA Lee, Antibiofilm activity of an EDTA-containing nanoemulsion on multidrug-resistant Acinetobacter baumannii, Artificial Cells, Nanomedicine, and Biotechnology, 2018: May 2. YH Yoon, K Ramlingam, DR Bienek, Lee VA, T You, R Alvrez, Antimicrobial activity of nanoemulsion in combination with cetylpyridinium chloride on multi-drug resistant Acinetobacter baumannii. Antimicrobial Agents and Chemotherapies, 2013, May 13 [Epub ahead of print], PMCID PMC3719747. Karthikeyan R, Frohlich NC, Lee VA. 2013. Effect of a cetylpyridinium chloride-containing nanoemulsion on dental unit waterlines. J Dent Sci 2013:8(3):333-336 PMC Journal – In Process. Karthikeyan R, Amaechi BT, Rawls HR, Lee VA. 2012. Antimicrobial activity of nanoemulsion against cariogenic planktonic and biofilm organisms. Archives Oral Biol; 57(1):15-22. (PMCID: PMC3210916). Karthikeyan R, Amaechi, BT, Rawls, HR, Lee VA. 2011. Antimicrobial activity of nanoemulsion on cariogenic Streptococcus mutans, Archives of Oral Biology; 56(5):437–445. PMCID: PMC3064956 Lee VA, Karthikeyan R, Rawls HR, Amaechi BT. 2010. Anti-cariogenic effect of a cetylpyridinium chloride-containing nanoemulsion, J Dent; 38(9): 742-749. (PMCID: PMC2918665) Lee VA, Cardenas HL, Rawls HR, Rubber-toughening of dimethacrylaate dental composite resin. J Biomed Mater Res B Appl Biomater. 2010 Aug:94(2):447-54. PMCID: PMC2900935 Rejali D, Lee VA, Abrashkin KA, Humayun N, Swiderski DL, Raphael Y. 2007. Cochlear implants and ex vivo BDNF gene therapy protect spiral ganglion neurons. Hear Res; 228(1-2):180-7. (PMCID: PMC2692458) Lee VA, Rawls HR. 2005. Compliant phase reduces polymerization shrinkage in dental composite resin. J Appl Polym Sci; 97(6):2306-2310. Lee VA, Craig RG, Filisko FE, Zand R. 2005. Microcalorimetry of the adsorption of lysozyme onto polymeric substrates. J Coll Interface Sci; 288(1):6-13. (PMID : 15927555)

X Cui, Lee VA, Y Raphael, J Wiler, J Hetke, DJ Anderson, DC Martin. Surface modification of neural recording electrodes with conducting polymer/biomolecule blends. J Biomed Mat Res. 2001:56(2):261-272. PMID : 11340598 Lee VA, RG Craig, FE Filisko, R Zand. Preparation and characterization of high-surface-area polymer substrates for microcalorimetry. J Biomed Mat Res. 1996:31:51-62. PMID: 8731149 Jing Li Li, J.; Peng, J.; Risinger, A.L.; Mooberry, S.L. Hydrolysis Reactions of the Taccalonolides Reveal Structure Activity Relationships. J. Nat. Prod. 2013, 76 (7), 1369–1375. PMID#23855953. Risinger, A.L.; Li, J.; Bennett, M.J.; Rohena, C.C.; Peng, J.; Schriemer, D.C.; Mooberry S.L. Taccalonolide Binding to Tubulin Imparts Microtubule Stability and Potent In Vivo Activity. Cancer Res. 2013, 73 (22), 6780-6793. PMID#24048820. Li, J.; Risinger, A.L.; Mooberry, S.L. Taccalonolide Microtubule Stabilizers. Bioorg. & Med. Chem. 2014, 22 (18), 5091-5096.

Peng, J.; Risinger, A.L.; Li, J.; Mooberry, S.L. Synthetic Reactions with Rare Taccalonolides Reveal the Value of C-22,23 Epoxidation for Microtubule Stabilizing Potency. J. Org. Chem. 2014, 57 (14) 6141-6149. Risinger, A.L.; Li, J.; Du, L.; Benavides, R.; Robles, A.J.; Cichewicz, R.H.; Kuhn, J.G.; Mooberry, S.L. Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ. J. Nat. Prod. 2017, 80 (2), 409-414. Li, J.; Pawar, R.; Krynitsky, A.J.; Noonan, G.O. Sensitive and Rapid Quantitation of Three Ginkgolic Acids in Dietary Supplements of Ginkgo. Phytochem. Anal. Submitted. Wu, Charles, Dou, Jinhui, Lee, Su-Lin, Taylor, Cassandra, Li, Jing, Lee, Sau and Yu, Lawrence. Scientific and Regulatory Challenges of Developing Plant-Derived as Botanical New Drug in the United States, from FDA Perspective. In preparation.

Hsu, Yu-Yi, Li, Jing and Tsong, Yi. Assessing Quality Consistency of Botanical Products using Chromatographic Fingerprint Data. Analytica Chimica Acta. Submitted 2018. Peter LoCoco Samanamu C, LoCoco P, Richards A. 2007. From gallium to thallium: Group 13 one-dimensional polymers. Inorganica Chimica Acta 360: 4037-4043.

Samanamu C, LoCoco P, Woodul W, Richards A. 2007. Copper halide clusters and polymers supported by bipodal heteroelemental ligands. Polyhedron 27: 1463-1470.

LoCoco P, Risinger A, Smith H, Chavera T, Berg K, Clarke WP. 2017. Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy. eLife. PMID: 29125463

França CM, Riggers R, Muschler JL, Widbiller M, LoCoco PM, Diogenes AR, Bertassoni LE. 2019. 3D-imaging of whole neuronal and vascular networks of the human dental pulp via CLARITY and light sheet microscopy. Scientific Reports. In Review.

LoCoco P, Sullivan L, Jamshidi R, Berg K, Clarke WP. 2019. Enhanced cold and mechanical anti-allodynia in the rat hindpaw by peripheral delta opioid receptor activation following exposure to an inflammatory mediator. European J Neuro. In Review.

Jennings E, Smith H, LoCoco P, Sullivan L, Jamshidi R, Berg K, Clarke WP. 2019. Aged-related changes in peripheral nociceptor function. Pain. In Review.

Boyd J, LoCoco P, Furr A, Bendele M, Arris D, Hargreaves K. 2019. A high ω-6 polyunsaturated fatty acid diet generates a neuropathy- like phenotype in mice. Nature Medicine. To be submitted.

LoCoco P, Espitia Olaya C, Lai Z, Hargreaves K. 2019. A reliable method to extract high-integrity RNA from human skin biopsies. Pain Reports. To be submitted.

LoCoco P, Furr A, Boyd J, Hargreaves K. 2019. Oxidized metabolites of ω-6 polyunsaturated fatty acids mediate the development of neuropathic pain associated with diabetic dyslipidemia. In preparation.

Boyd J, LoCoco P, Hargreaves K. 2019. Sex-dependent differences in diet-associated neuropathy. J Clin Inv. To be submitted.

LoCoco P, Locke E, Tobon A, Hargreaves K. 2019. Identification of novel gene networks with mRNA-Seq using skin biopsies from diabetic neuropathy patients. In preparation.

LoCoco P, Espitia Olaya C, Locke E, Tobon A, Hargreaves K. 2019. Contributions of cutaneous inflammasomes in cryptogenic and diabetic neuropathic pain: an observational study. In preparation.

LoCoco P, Boyd J, Li Q, Chang F, Furr A, Ruparel S, Hargreaves K. 2019. PLA2G16 regulates peripheral nociceptive input through linoleate metabolism. Nature. In preparation.

LoCoco P, Widbiller M, Austah O, Diogenes A, Hargreaves K. 2019. Implementation of a clearing approach with intact human teeth. In preparation.

Furr A, LoCoco P, Hargreaves K. 2019. Characterization of the pain phenotype following a partial thickness burn injury to the mouse hindpaw. In preparation.

Andrey Malakhov Malakhov A., Wen J., Zhang B.X., Wang H., Geng H., Chen X.D., Sun Y., Yeh C.K. Rechargeable anticandidal denture material with sustained release in saliva. Oral Dis. 2016, Jul;22(5):391-8. doi: 10.1111/odi.12456. Epub 2016 Mar 10. PMID: 26855200 PMCID: PMC4900923

Jennifer McDaniel McDaniel JS, Holt AW, Por ED, Eriksson EE, Johnson AJ, Griffith GL. The utilization of an ocular wound chamber on corneal epithelial wounds. Clin Ophthalmol, 12:903-11, 2018.

Holt AW, McDaniel JS, Bramblett GT, Eriksson EE, Johnson AJ, Griffith GL. Use of an ocular wound chamber for the prevention of exposure keratopathy in a guinea pig model. Wound Repair Regen, [Epub ahead of print], 2018.

Rios JD, Choi JH, McDaniel JS, Becera S, Bice L, Johnson P, Cleland JM, Glickman RD, Reill MA, Gray W, Sponsel WE, Lund BJ. Altered Expression of Aquaporin 1 and Aquaporin 5 in the cornea after primary blast exposure. Mol Vis, [Accepted], 2018.

McDaniel JS, Wirostko B, Sprague C, Johnson AJ, Griffith GL. The effects of phosphate buffered saline on corneal chemical alkali burns. J Ocul Dis Ther, [Epub ahead of print], 2018.

Griffith GL, Wirostko B, Lee H-K, Cornell LE, McDaniel JS, Zamora DO, Johnson AJ. Treatment of corneal alkali burns with a crosslinked thiolated hyaluronic acid film. Burns, 44(5): 1179-86, 2018.

McDaniel JS, Antebi B, Pilia M, Hurtgen B, Belenkiy S, Necsoiu C, Cancio L, Rathbone CR, Batchinsky A. Quantitative assessment of optimal bone marrow site for the isolation of porcine mesenchymal stem cells. Stem Cells Int., [epub ahead of print], 2017.

Cornell LE, Greene W, Haich RO, Magnum LC, Garcia GR, Guymon CH, Akers KS, Landry J, McDaniel J, et al. Proceedings of the 4th annual United States Army Institute of Surgical Research undergraduate research internship program 2016. J Transl Med, 15(Suppl 2):19, 2017.

McDaniel JS, Pilia M, Raut V, Ledford J, Shiels SM, Wenke JC, Barnes BR, Rathbone CR. Alternatives to autograft evaluated in a rabbit segmental bone defect. Int Orthop, 40(1):197-203, 2016.

McDaniel JS, Pilia M, Ward CL, Pollot BE, Rathbone CR. Characterization and multilineage potential of cells derived from isolated microvascular fragments. J Surg Res, 192(1): 214-22, 2014.

Pilia M, McDaniel JS, Guda T, Chen XK, Rhoads RP, Allen RE, Corona BT, Rathbone CR. Transplantation and perfusion of microvascular fragments in a rodent model of volumetric muscle loss injury. Eur Cell Mater, 28:11-23, 2014.

McDaniel JS, Akula Suresh Babu R, Navarro MM, LeBaron RG. Transcriptional regulation of proteoglycan 4 by 17b-estradiol in immortalized baboon temporomandibular joint disc cells. Eur J Oral Sci, 122(2): 100-8, 2014.

Mu YD, Xu Y, Contreras CI, McDaniel JS, Donly KJ, Chen S. Mutational analysis of AXIN2, MSX1, and PAX9 in two Mexican oligodontia families. Genet Mol Res, 12(4): 4446-58, 2013.

Corona BT, Garg K, Ward CL, McDaniel JS, Walters TJ, Rathbone CR. Autologous minced muscle grafts: A tissue engineering therapy for the volumetric loss of skeletal muscle. Am J Phys.Cell Phys, 305(7):C761-75, 2013.

Corona BT, Wu X, Ward CL, McDaniel JS, Rathbone C R, Walters TJ. The promotion of a functional fibrosis in skeletal muscle with volumetric muscle loss injury following the transplantation of muscle-ECM. Biomaterials, 34(13): 3324-35, 2013.

Mu Y, Xu Z, Contreras CI, McDaniel JS, Donly KJ, Chen S. Phenotype characterization and sequence analysis of BMP2 and BMP4 variants in two Mexican families with oligodontia. Gen Mol Res 11(4): 4110-20, 2012.

McDaniel JS, Feng JS, Chuang HH, Rakian A, Huang O, Xu X, Steffensen B, Donly K, MacDougall M, Chen S. Binding of amelogenin to MMP-9 and their co-expression in developing teeth. J Mol Histol, 43(5): 473-85, 2012.

Feng F, Yang G, Gluhak-Heinrich J, Yang W, Wang L, Chen Z, Schulze McDaniel J, Donly K, Harris SE, MacDougall M, Chen S. Abnormalities in the enamel in BMP2-deficient mice. Cells Tissues Organs, 194(2-4): 216-21, 2011.

Chen S, Santos L, Wu Y, Vuong R, Gay I, Schulze J, Chuang H, MacDougall M. Altered gene expression in human cleidocranial dysplasia dental pulp cells. Arch Oral Biol, 50(2):227-36, 2005. Cong-Dat Pham Pham CD, Hartmann R, Müller WEG, de Voogd N, Lai DW, Proksch P (2013) Aaptamine derivatives from the Indonesian sponge Aaptos suberitoides. J. Nat. Prod. 76: 103–106 Pham CD, Weber H, Hartmann R, Wray V, Lin WH, Lai DW, Proksch P (2013) New cytotoxic 1,2,4-thiadiazole alkaloids from the ascidian Polycarpa aurata. Org. Letters 15: 2230–2233 Pham CD, Hartmann R, Böhler P, Stork B, Wesselborg S, Lin WH, Lai DW, Proksch P (2014) Callyspongiolide, a cytotoxic macrolide from the marine sponge Callyspongia sp. Org. Letters, 16: 266-269. Pham CD, Hu JC-C, Simmer JP, Smith CE, Chun Y-HP Endocytic Pathways of Amelogenin During Enamel Formation (manuscript in preparation) Pham CD, Demeler B, Simmer JP, Chun Y-HP Characterization of amelogenin nanospheres with analytical ultracentrifugation. J. Struct. Biol. (manuscript in preparation) Chun YHP, Cervantes Mendez MJ, Abudawood A, Mabry JC, Pham CD Pathophysiology of enamel hypomineralization. Front. Physiol. (manuscript in preparation) Pham CD, Hu JC-C, Simmer JP, Hu Y, Smith CE, Chun Y-HP Endocytosis and Enamel Formation (2017). Front. Physiol., https://doi.org/10.3389/fphys.2017.00529 Akone SH, Pham CD, Chen HQ, Ola ARB, Kang FN, Proksch P Epigenetic modification, co-culture and genomic methods for natural product discovery (2018). Physical Sciences Reviews 2018/DeGruyter. https://doi.org/10.1515/psr-2018-0118

Kevin Scott Redding S, Bhatt B, Rawls HR, Siegel G, Scott K, Lopez-Ribot J. Inhibition of Candida albicans biofilm formation on denture material. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 May;107(5):669-72. doi: 10.1016/j.tripleo.2009.01.021. PubMed PMID: 19426921.