Pathology of Viral Hepatitis

Never offer the devil (desire) a ride,He always want to be in the driving seat!

-- BK1CPC 4.2.3 2013 yellow eyesFatigue / Anorexia..?Nausea, Vomiting..?Haematemesis ?Itching..? Fever..?Abdominal distension slow..?Bleeding / Bruising..?10 stubbies/day /more..?Many Tattoos..?BMI if low / High..?

2Mr. T.D. 50 year old, presents to his GP. My stomach appears big and my wife has noticed a yellow tinge in my eyes. CASE STUDY 1Abd distension, fatigue, yellow discoloration of eyes for 1 weekPresenting Symptoms:

Liver failureLiver failurePortal HypertensionObstructive jaundice.Hepatitis.Cirrhosis.Vit-K deficiency.Alcoholic hepatitis.Viral Hepatitis (B/C)Anorexia / Obesity steatosis.

Differential Diagnosis: Hepatitis: Alcoholic/Infective/Malignant/Drug/ToxinsAcute / Chronic? Primary/Secondary? HBV / HCV, CMV, Lepto, Dengue, Melioidosis.2Case2: Mr.GG, 48y, fatigue & yellowAbdominal distension, fatigue, yellow sclera 6 weeks.Hardware business, Alcohol 40units / wk.Travel: Thailand, had tattoo / surgery / transfusion.. * PE: abdomen nil sig. mild RUQ tenderness. No organomegaly.Differential: Acute hepatitis.CMV, Lepto, Hep A,B,C..Hepatitis - AlcoholChronic hepatitis.Drugs, toxins,

3

AST = 1320 U/l ALT = 1780 U/lAlk. Phos. = 133 U/lGGT = 192 U/lHep B Serology Hep B sAg +ive Hep B sAb