creativity ,dementia and brain reserve capacity l fornazzari, c fischer, m saragosa l ringer

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Creativity ,Dementia and Brain Reserve Capacity L Fornazzari, C Fischer, M Saragosa L Ringer Memory Clinic St Michael Hospital University of Toronto, Canada. - PowerPoint PPT Presentation

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Page 1: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

www.adi2011.org

Page 2: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

www.adi2011.org

Creativity ,Dementia and Brain Reserve Capacity

L Fornazzari, C Fischer, M Saragosa L Ringer Memory Clinic St Michael Hospital University of Toronto, Canada

Page 3: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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The preservation of Art when other cerebral functions are failing -

another precious legacy from artists

Luis Fornazzari MD FRCPCMemory Disorders Clinic

St. Michael’s HospitalDivision of Neurology, Department of Psychiatry

University of Toronto

Page 4: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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Artful minds have been with us for more than 50,000 years

but the process probably took millions of years to develop

Page 5: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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Art and other cognitive functions represent diverse communication forms, each

with potentially infinite combinations.

Page 6: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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Regardless of the timing, both modes of human

communication, art and cognition, relied on pre-

existing brain mechanisms that supported the highly abstract metaphorically

thinking of the human brain.

Page 7: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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But both are not necessarily related:

Language may be severely affected, while art expression

and comprehension are preserved with minimal

impairment or no impairment at all.

Page 8: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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Chauvet Pont d’Arc (37-35,000 BC)

Page 9: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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Lascaux on Mortignac (15-13,000 BC)

Page 10: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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16-14, 000 BC

Page 11: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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After Altamira all is decadence!!

Pablo Picasso

Page 12: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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BilingualismArts

Page 13: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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“de Kooning’s late colours and forms: dementia,

creativity, and the healing power of art.”

Espinel CH. Lancet 1996 Apr 20;347(9008):1096-8.

Page 14: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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Brain surface projection of activated areas during passive music listening in control subjects and

musicians

Source: Ohnishi T, Matsuda H, Asada T, et al. “Functional Anatomy of Musical Perception in Musicians. Cerebral Cortex, Aug 2001;11:754-760

Page 17: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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“Maurice Ravel and right-hemisphere musical creativity:

influence of disease on hislast musical works?”

Amaducci L, Grassi E, Boller F. Eur J Neurol, 2002; 9:75-82.

Page 18: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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Ravel’s Brain

By Justine Sergent

Page 19: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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“I had to go on writing, because I wouldn’t be able to go on without writing. It is the only function that

works for me, and without a function, we die”

Farley Mowat, Sept 2006, at 85 years of age

Page 20: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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“The effects of very early Alzheimer’s disease on the

characteristics of writing by a renowned author”

P Garrard, L M Maloney, J R Hodges, K Patterson Brain. (2005) 128, 250-260

Page 21: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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“My rewards have been great. Friends have helped. The documentation of me in the Who’s Who books on both sides of the pond please me

and validate me to me. I can go and look at them and reaffirm my work and my having been here. But the greatest reward are the work itself, that

its been a good life and that it’s been a good way to live. Coming up seventy, I’ve survived and enjoyed it and look forward to each day I’m

granted”

MH

Page 22: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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“I’m not cutting edge; I am perhaps a synthesizer. I call myself

Impressionist/Expressionist. The sources from Byzantine, Medieval Art, German Expressionist Art, pre and post World Wars I&II, the Holocaust in Germany and the other Holocaust in Japan, and the deaths in my family. I can also see the

abstract qualities of the pulls and balances in my work. I guess that’s the XX Century”

M. H

Page 23: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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“In 1970 I left the USA for Canada. In ’68 I had said I would leave if Nixon gained

office. He did, so I did”

Page 24: Creativity ,Dementia and Brain Reserve Capacity    L Fornazzari, C Fischer, M Saragosa  L Ringer

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CNS lesions:White matter lesionsBrain atrophyPlaques, tanglesVascular damageMetabolic/Endocrine disease Injury

Clinical Expressionof Disease

Other Influences onDisease Expression:PersonalityHealth Service Delivery and UptakeCultural norms

Brain Size & Function:Neural NetworkDensity & Complexity Premorbid Cognitive AbilityProcessing Capacity & Efficiency

Influencing Factors:GenesEarly Social and Material EnvironmentEducational & Occupational AttainmentPhysical HealthHealth Behaviours & LifestyleBilingualismArt

Richards & Deary: Cognitive Aging and Development

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I like for you to be still

I like for you to be still it is as though you wereabsent

and you hear me from far away and my voice does not touch you.

It seems as though your eyes had flown away and it seems that a kiss had sealed your mouth. Pablo Neruda, 1924 “Twenty Love poems and a

song of Despair”

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An Idiomatic Plea

• The presentation today was not a piece of cake. I skate on thin ice, but not in hot water, I hope.

I intended to rock your brains, so don’t lose your grip, but hold your horses and bury the hatched when you speak your mind. Please don’t give me the cold shoulder, because I would give the world for your comments. Naturally I would like to leave this conference with flying colours and not under the weather.