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CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU Dept Brugmann University Hospital Vicenza , 37 th course on AKI and CRRT

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Page 1: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU

CRRT: Acid-Base and Electrolytes Corrections

Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist

Professor & Co-Director of ICU Dept

Brugmann University Hospital

Vicenza , 37 th course on AKI and CRRT

Page 2: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU

Agenda

•Infusion of Bicarbonate : So bad in 2019 ?

• Bicarbonate in CRRT : how to use it ?

•Hypernatremia : how to handle ?

•Hyponatremia : what to do ?

•Hyperphosphoremia : Someting to kook after..

•Hypophosphoremia : How to avoid ?

•Hypomagnesemia : What to do ?

•Calcium stores : something to worry about ?

•Conclusions/perspectives

Page 3: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU

Acid Base :Bicarbonate infusions

Page 4: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 5: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 6: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 7: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU

Acid Base :Bicarbonate-How to do in CRRT

Page 8: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 9: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 10: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU

Electrolytes :Hypernatremia

Page 11: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 12: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 13: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU

Electrolytes :Hyponatremia

Page 14: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 15: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU

Electrolytes :Hyperphosphatemia

Page 16: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 17: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU

Electrolytes :Hypophosphatemia

Page 18: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 19: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 20: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 21: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU

Electrolytes :Hypomagnesemia

Page 22: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 23: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 24: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU

Electrolytes :Hyperkaliemia

Page 25: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 26: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU

Electrolytes :Hypocalcemia

Page 27: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU
Page 28: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU

1) Bicarbonate infusion can be given safely to delay

CRRT

2) High bicarbonate load in CRRT do not increase PCO²

3) Correction of Hyperphophoremia needs customisation

4) Hypophophoremia needs a multidiciplinary team

5) Hypomagnesemia can be corrected without

supplementation

6) Refractory Hyperkaliemia may need a customized

approach

7) In long Run CRRT, decalcification will occur..

8) Protocols are the key stone to correct these side effects

Conclusions – Take home messages

Page 29: CRRT: Acid-Base and Electrolytes Corrections...CRRT: Acid-Base and Electrolytes Corrections Prof Patrick Honoré,MD,PhD,FCCM -Intensivist-Nephrologist Professor & Co-Director of ICU

BELIEVE THOSE WHO ARE SEEKING THE TRUTH.

DOUBT THOSE WHO FIND IT.

Andre Gide

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