ctiip coordination. contract period of performance digital pathology and integrative query –july...

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CTIIP Coordination

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Timeline – Digital Pathology Support native WSI format in caMicroscope –Delivered to QA – March 2015 Tools and libraries to support the creation, consumption and management of PathAIM –Delivered to QA – August 2015 Support analytical services –Delivered to QA – November 2015 Pilot a data mashup and integrative query system –Delivered to QA – December

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Page 1: CTIIP Coordination. Contract Period of Performance Digital Pathology and Integrative Query –July 24,…

CTIIP Coordination

Page 2: CTIIP Coordination. Contract Period of Performance Digital Pathology and Integrative Query –July 24,…

Contract Period of Performance• Digital Pathology and Integrative Query

– July 24, 2014 – January 23, 2016• DICOM WG-30

– June 26, 2014 – June 25, 2015• Pilot Challenges

– December 18, 2014 – June 17, 2016• Co-clinical and animal model data

– April 15, 2015 – April 14, 2016

Page 3: CTIIP Coordination. Contract Period of Performance Digital Pathology and Integrative Query –July 24,…

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Timeline – Digital Pathology• Support native WSI format in caMicroscope

– Delivered to QA – March 2015• Tools and libraries to support the creation, consumption

and management of PathAIM – Delivered to QA – August 2015

• Support analytical services– Delivered to QA – November 2015

• Pilot a data mashup and integrative query system– Delivered to QA – December 2015

Page 4: CTIIP Coordination. Contract Period of Performance Digital Pathology and Integrative Query –July 24,…

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Timeline - Pilot Challenges• Evaluation of existing challenge platforms, standards, tools and

technologies– Report due March 31, 2015

• Develop MedICI system to support imaging (radiology and digital pathology) challenges– Development March to October 2015– Deliver to QA – September 2015

• Demonstrate the ability to host/execute pilot challenges using the challenge management system– Deploy Challenge Management System – September 2015– Execute first challenge – October / November 2015– Fine-tune system – November 2015 – January 2016– QA refinements – March 2016– Execute two more challenges – March to June 2016

Page 5: CTIIP Coordination. Contract Period of Performance Digital Pathology and Integrative Query –July 24,…

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Timeline – Co-clinical/animal model• Submit Whole Slide Images and Demographics

– May – October 2015• PathAIM mark up and annotations

– June – October 2015• Prepare CMGI Images

– May – July 2015• Mark up In-Vivo Images

– July – August 2015• Submit CMGI images

– July – November 2015• Identify and prepare human BrCa cases

– July – September 2015 • Submit human BrCA Images

– November 2015 – April 2016

Page 6: CTIIP Coordination. Contract Period of Performance Digital Pathology and Integrative Query –July 24,…

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Dependencies / Linking of ProjectsCreation of PathAIM annotations and markups for animal images

• DigPath– Tools and libraries to support the creation, consumption and management of

PathAIM • Delivered to QA – August 2015

• Co-Clinical– Submit Whole Slide Images and Demographics

• May – October 2015– PathAIM mark up and annotations

• June – October 2015

UC Davis team to provide input on markup and annotations for animal imagesUC Davis team = user acceptance testing during development

Page 7: CTIIP Coordination. Contract Period of Performance Digital Pathology and Integrative Query –July 24,…

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• DigPath– Pilot a data mashup and integrative query system

• Delivered to QA – December 2015• Co-clinical

– Submit Whole Slide Images and Demographics• May – October 2015

– PathAIM mark up and annotations• June – October 2015

– Prepare CMGI Images• May – July 2015

– Mark up In-Vivo Images• July – August 2015

– Submit CMGI images• July – November 2015

• Need to agree where to store the data to make them accessible to the query system.

Dependencies / Linking of ProjectsProviding animal model/co-clinical data for integrated queries

Page 8: CTIIP Coordination. Contract Period of Performance Digital Pathology and Integrative Query –July 24,…

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• Pilot Challenges– Execute two more challenges

• March to June 2016• Co-clinical

– PathAIM mark up and annotations• June – October 2015

– Mark up In-Vivo Images• July – August 2015

– Submit CMGI images• July – November 2015

– Submit human BrCA Images• November 2015 – April 2016

Dependencies / Linking of ProjectsProviding animal model/co-clinical data for pilot challenge

Page 9: CTIIP Coordination. Contract Period of Performance Digital Pathology and Integrative Query –July 24,…

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Dependencies / Linking of ProjectsDICOM for animal model images

• Co-clinical– Submit CMGI images

• July – November 2015• DICOM WG-30

– Collecting images now– Images can be used as test cases

• DCB funded project develops DICOM wrapper tool– Coordination with DCB team (Rubin/Beck) needed

Page 10: CTIIP Coordination. Contract Period of Performance Digital Pathology and Integrative Query –July 24,…

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Working with the QA team• Digital Pathology

– QA Engineer Reza Mehri– Requirements before we go in QA

• Design Document• Requirements Definition Document• Architectural Review Checklist (ARC)

– https://wiki.nci.nih.gov/display/sysdeploy/CTIIP+Digital+Pathology+ARC

• Provision Target Environment (PTE)– https://

wiki.nci.nih.gov/display/sysdeploy/CTIIP+Digital+Pathology+PTE– App scan for security vulnerabilities– 508 compliance scan– Use the same QA server for Dig Path and Pilot Challenges?

Page 11: CTIIP Coordination. Contract Period of Performance Digital Pathology and Integrative Query –July 24,…

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Working with the technical writer• Carolyn Klinger

– Goal = make the CTIIP wiki public– User Documentation– Installation Guides

Page 12: CTIIP Coordination. Contract Period of Performance Digital Pathology and Integrative Query –July 24,…

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Coordination Meetings• Once a month have all teams meet in a one-hour

meeting to– Report progress– Discuss interactions and data delivery– Feedback on tools

• Find a timeslot

Page 13: CTIIP Coordination. Contract Period of Performance Digital Pathology and Integrative Query –July 24,…

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Resources• CTIIP wiki

– https://wiki.nci.nih.gov/x/XQJjCg