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CURRICULUM VITAE DR. SAMINA HYDER HAQ

Email addresss: dr_s_haq@yahoo.com

shaq@ksu.edu.sa

ORCID Account: https://orcid.org/0000-0002-8617-3767 KSU web Page: http://fac.ksu.edu.sa/shaq Web of science researcher ID: J-7453_2019 Publons Link: https://publons.com/researcher/1583469/samina-hyder-h-haq/ Google Scholar Web Page: https://scholar.google.com/citations?user=rma1vKwAAAAJ&hl=en LinkedIn: https://www.linkedin.com/in/samina-hyder-49531369 PERSONAL DETAILS

Name: Dr. Samina Hyder HAQ

Present status: Assistant Professor

Local Address: College of Science

King Saud University

P.O.Box: 22452

Riyadh 11495, Saudi Arabia

Nationality: British/Pakistani

Marital status: Married with four children

PROFESSIONAL SUMMARY

A Senior Biochemist by profession, having completed a Doctorate in Biochemistry

from the Medical School, University of Manchester, United Kingdom. Experienced

in research in Biochemistry and Molecular Biology fields and worked with the

‘Connective Tissue Research Group (U.K)’ where most of the pioneering works was

done in the Collagen field. My research at the Medical School Manchester (U.K)

developed and excelled in Tissue Culture Techniques to study Collagen synthesis in

cultured avian and mammalian cells. This was one the first research groups in the

world to identify and characterize novel type X collagen in vivo and in vitro.

Experienced in curriculum planning and academic teaching using logic and reasoning.

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Contribution to King Saud university

Joined King Saud University in April 2008 when there was a major new shift towards

updating all the major taught and practical courses of the Biochemistry department for

the process of Accreditation of King Saud University. At this critical point, I was

actively involved in designing, writing, editing, and proofreading most of the Practical

courses such as BCH 361, BCH 462, BCH 321, BCH 447. I took an active part in

designing and formatting BCH 497 course objective and included and introduced a

poster day for the Graduate students of the Biochemistry department. I arranged a

successful poster day for Biochemistry Department using my own resources for

printing and designing poster certificates and monetary gifts. By the grace of ALLAH,

now poster day is the main event for graduates in the whole College of Science.

I had the vision for all the gifted and able students, who were not able to find suitable

job opportunity, to be able to participate in research activities and publishing research

papers. For this, I encouraged few graduate students to work in research labs with me,

and Alhamdulillah they published with me.

Interdisciplinary research is vital for the success of any department. In my opinion, no

department can achieve research excellence without the cooperation of inter-

departmental as well as international collaboration. I have promoted interdisciplinary

cooperation within the college of science, working tirelessly with Botany &

Microbiology department as well as the Physics & astronomy department, and

successfully published many research papers in high impact factor journals.

During the last couple of years, I devoted much of my time in hands-on training in

different research techniques with my postgraduate students; most noteworthy were

cell and tissue culture and molecular biology techniques. Some of my trained

postgraduate students are working in King Faisal hospital and were widely praised and

acknowledged for their expertise in cell culture and lab work.

I had a number of publications alone, and with my graduate and postgraduate students

mainly during the last couple of years because of the provision of a feasible research

working environment by the current Head of department. I have at least more than 10

publications during this period and a number of other publications in process. I hope

that in the future, I would continue to benefit graduate and undergraduate students at

King Saud University.

.

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EDUCATION & QUALIFICATIONS 1986 to 1990 Ph.D. Biochemistry in Faculty of Medicine, United Kingdom

The Medical School, University of Manchester, UK Thesis: Gene Expression of Type X Collagen

1982 to 1984 M.Sc. Biochemistry, Genetics, Molecular Biology

The Quad-i-Azam University, Islamabad, Pakistan

1980 to 1981 B.Sc. Chemistry, Zoology, Botany

University of Punjab, Pakistan

July 1980 Intermediate (HSSC) Examinations (First Division)

June 1977 Matric (SSC) Examinations (First Division)

RESEARCH/TEACHING EXPERIENCE

1987 to 1995 Medical School University of Manchester, United Kingdom

Research Scientist: Methylation and Gene Expression of Collagen

Biochemistry Lecturer: Undergraduate Students. This included

Laboratory and Practical Work supervision. 2000 to 2007 Part-time Local Private Tuition

Part-time local tuition for students studying Biology, Chemistry for the British and American Curricula including the International Baccalaureate

(IB) and A Levels.

2002 to 2008 Al Iqbal International Schools

(Head of Science Department)

Teaching Science to High School students and also involved in curriculum planning for the British IGCSE Science subjects.

2008 to present Assistant Professor at King Saud University

College of Science

Department of Biochemistry

2009 to 2011 worked in summer as a visiting researcher in Kennedy institute for

Rheumatology at Oxford University in Cell signaling Lab with renewed

professor Dr. Tonia Vincent.

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Supervision & publication of major Undergraduate Research Projects:

1. In-vitro inhibition of Camel Hepatic GST by quercetin.

2. DNA damage by formaldehyde in brain tissue culture

3. Neuroprotective effect of vitamin E in sheep brain tissue culture.

4. Neuroprotective Role of Quercetin in Rat’s brain tissue culture.

5. Neuroprotective role of vitamin D in brain tissue culture.

6. Antioxidant, anticancer activity of green algae chaetomorpha.

7. Antioxidant activity of Rhodophyta algae collected from Arabian gulf. 8. Phytochemical analysis and antidiabetic property of green algae chaetomorpha.

9. Hepatotoxicity of PG coated graphene oxide nanoparticles.

10. Neurotoxicity of PG coated GO nanoparticles.

Supervision Of Masters Research Projects:

1. Co supervisor for Yusra Al Yafee (2011) MSc Project Title: Neuroprotective role of Glutathione in brain.

2. Supervisor for Reham Al Johri (2017)

Title: Neuroprotective role of Vitamin D in primary neuronal cultures from Rat’s brain.

3. Supervisor for Hajar (2017)

Title: Elucidation of The Role of Camel Lens a lp ha -crystallin in The Folding and Stability of z e t a -crystallin

4. Supervisor for Sarah Dossary (2017) Title: Molecular Characterization and Phylogenetic Analysis of RSV Strains by Nucleotide Sequence Determination of Partial G protein Gene

5. Supervisor for Ebtesam Al Sulami (2018)

Title: The effect of Vitamin D treatment on VDR expression in primary cortical cell culture.

6. Supervisor for Nora Alkershain (2018) Title: Effect of Melatonin and Vitamin D on P53 expression in breast cancer cell line.

7. Supervisor for Manal AL Malki (2018)

Title: Synergistic Effect of Melatonin and Vitamin D on the Gene Expression of Bcl-2 and

Bax In breast Cancer Cell Lines

INTERNATIONAL SEMINARS and RESEARCH MEETINGS ATTENDED

1. Connective tissue society meeting in Amsterdam (Holland) 1988

2. Royal Society meeting on ‘DNA Methylation and Gene Regulation’ Feb 1989

Cambridge University (U.K).

3. Seminar on Biomatrix at Cambridge University (UK) 1989.

4. Annual Connective Tissue society meeting in Manchester (UK) 2000.

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5. XVIII annual FECTS (federation of European connective tissue society)

meeting in Brighton, England

6. Annual meeting of connective tissue society on ‘Stem Cell’ in Manchester

16-18 July 2007.

7. Attended 6- w e e k Work shop in Cell signaling Research Lab in London at

‘Kennedy institute of Rheumatology’ Oxford University from 18th

July to 26th

August 2011.

8. Attended Conference on ‘Biotechnology’ in Riyadh organised by KACST in

2012.

9. Attendance in the conference organized by Prince Mutaib Chair of Biomarkers in

osteoporosis. The topic was ‘Health lecture series.’’ in Riyadh on 6 April 2015

10. Workshop organized by BIOING computer department on Bioinformatics on Data

base of Life (DNA,RNA and Protein) on 27th Nov 2014 and 13Nov 2014

11. Participated in ‘’Genomics and precision medicine ‘’ at British embassy and King Saud

university on 22nd and 23rd March 2017

12. Speaker oral presentation on research paper title ‘’Neuroprotective role of Vitamin D in

primary neuronal cultures.’’ In 15h European neurology conference held in London 29th

and 30th august 2017.

13. Poster presentation in annual poster competition in Abu Dhabi (2018) Title: antioxidant

and antitumor activity of green algae .

14. Presented poster in Breast cancer conference in London (2018) Title; expression of p53

gene in breast cancer cell line.

15. Presented poster in annual Breast cancer conference in London (2018) Title: gene expression of Bcl 1/Bax in breast cancer cell line.

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AWARDS & DISTINCTIONS

4Th prize for Poster competition organized by Ministry of Health Riyadh 2017.

Top student (the highest GPA) from Quaid i-Azam University Islamabad

1985-86

PhD Scholarship awarded from Ministry of Science and Technology

(Pakistan) in the area of ‘GENETIC Engineering & BIOTECHNOLOGY’

year 1986-1990

Harcourt (USA) Teaching award - 2006

Certificate for excellence in Teaching and as Head of Science Department at Al

Iqbal international School - 2005.

POSITIONS HELD

Elected General Secretary for the Student union at Quaid-i-Azam University,

(Palistan) 1984-85

Elected General Secretary for the Student union at Manchester University

(U.K) 1986-87

Science & Technology Scholar for the year 1986-1990

Post-Doctoral Research Associate year 1990-1995 university of Manchester

(U.K)

Head of Science department at Al Iqbal international school year 2004-08

Currently Assistant professor at KSU

Academic Committee Participation

1. Member of practical

committee.

2. Member of accreditation committee.

3. Co-coordinator for undergraduate course BCH 497.

4. Member of Graduate

committee.

5. Member of Alumni Committee

6. Member of postgraduate

committee

PROFESSIONAL AFFILIATIONS

Current Member of the British Connective Tissue Society U.K

Member of the Biochemical Society U.K

Manchester University Alumni Associate

Member of Biochemical Society U.K

Bone Research Society

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TEACHING EXPERIENCES: Over 20 years of teaching experience in teaching various Biochemistry courses.

Undergraduates Courses

Enzymology

Molecular Biology

Biochemistry of hormones

Cell membrane and Cell signaling

Techniques in protein extraction and purifications (BCH 497)

Biochemistry of Tissues

Bio membrane course for Masters

Toxicology and Carcinogenesis

How to make poster

How to Write references using endnote and Medley?

Ethics in Research

Post Graduate courses

Advances in Nutrition

In born errors of metabolism

Blood Biochemistry

Research Methodology

Enzyme extraction and purification Techniques

DNA extraction and characterization

Bio membrane

Advances in Metabolism

TEACHING LABORATORY TECHNIQUES

Taught a number of laboratory techniques to undergraduates and post graduate students such as

Enzyme extraction and purification

Enzyme Kinetics and effect of inhibitors

DNA extraction from prokaryotic and eukaryotic cells

Setting up primary neuronal and cortical cell culture

Setting up various cell lines (MCF-7, MCF-10, MDM)

Techniques for freezing and storing continuous cell lines

Western Blotting

RTPCR

PCR

Using LI-COR for in Cell western

PARTICIPATION IN SEMINARS AND WORKSHOP

Given seminar in Biochemistry Club on the following topics

1. Insight into the cell culture techniques.

2. Stem cell technology and its therapeutic implication

3. Gut and neural axis in Autism Studies

4. Ethics in Research.

5. Arranged two day workshops on Cell culture and Tissue culture

i. Feb 2017

ii. March 2018

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REVIEWERS FOR SCIENTIFIC PAPERS SUBMITTED TO INTERNATIONAL

JOURNAL ON WEB OF SCIENCE.

Journal of Central nervous system and disease

SAGE publications Journals

International journal of Biomedical Sciences

LIST OF PUBLICATIONS

Chapter in Book

Samina Hyder Haq, Iqraa Haq, Atheer Ali Alsayah, Abir Alamro and Amani AlGhamedi (December 17th 2018). Epigenetics and Cartilage Regeneration, Cartilage Tissue Engineering and Regeneration Techniques, Dimitrios D. Nikolopoulos, George K. Safos and Kalpaxis Dimitrios, IntechOpen, DOI: 10.5772/intechopen.82362. Available from: https://www.intechopen.com/books/cartilage-tissue-engineering-and-regeneration-techniques/epigenetics-and-cartilage-regeneration

Publications in peer reviewed Journals

2011

Novel metabolic biomarkers related to sulfur-dependent detoxification pathways in

autistic patients of Saudi Arabia. YA Al-Yafee, LY Al-Ayadhi, SH Haq, AK El-

Ansary BMC neurology 11 (1), 139

2014

1.Neuroprotective Role of Glutathione against Hydrogen Peroxide Induced Toxicity

to the Neuronal Cells in Culture. YL Yafaeea, A El-Ansary, SH Haq International

Journal of Science ; Basic and applied Research(IJSBAR) 13 (1 -16)

2. In-Vitro Inhibition of Camel Hepatic Glutathione Transferase by Quercetin.

Advances in Biochemistry. Vol. 2 No. 5, 2014, pp. 71-75. doi:

10.11648/j.ab.20140205.13 Ghada Al-Amro, Mohammad Ali Qorban,Samina

Hyder Haq

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2016

1.5-Aza-2'-deoxycytidine acts as a modulator of chondrocyte hypertrophy and

maturation in chick caudal region chondrocytes in culture SH Haq Anatomy & cell

biology 49 (2), 107-115

2. Effects of 5-Aza-2’ Deoxycytidine on Proliferation and Differentiation of

Embryonic Chick Caudal Region Chondrocytes in Culture. SH Haq Preprints 2016,

2016080176 (doi: 10.20944/preprints201608.0176.v2)

2018

1. Neuroprotective effect of quercetin in murine cortical brain tissue cultures

SH Haq, AA AlAmro Clinical Nutrition Experimental

https://doi.org/10.1016/j.yclnex.2018.10.002

2. Neuroprotective Role of Alpha-Tocopherol in H2O2 Induced Oxidative

Stress in Neonatal Sheep’s Brain Tissue Culture. SH Haq, H Nounou, AA

Alamro J Neurol Neurobiol 4 (1)

3. Samina Hyder Haq, Iqraa Haq, Atheer Ali Alsayah, Abir Alamro and

Amani AlGhamedi (December 17th 2018). Epigenetics and Cartilage

Regeneration [Online First], IntechOpen, DOI:

10.5772/intechopen.82362. Available from:

https://www.intechopen.com/online-first/epigenetics-and-cartilage-

regeneration/.

4. Neuroprotective role of vitamin D in primary cortical neuronal cultures.15th

European neurology conference in London august 2018. SH Haq J Neurol

Neurophysiol DOI: 10.4172/2155-9562-C1-058

5. Samina Hyder Haq, Nouf Omar Alafalaq and Reham Al-Johari

(2019)Vitamin D treatment

reverses induced oxidative stress damage to DNA. Pakistan Journal of

Biological Sciences, 22:8-14

6. Haq SH (2018) DNA Methylation Pattern and their Effect on Cellular

Morphology and Ageing. J Cell Signal 3: 181. DOI: 10.4172/2576-

1471.1000181

7. Reham AlJohri, Majid AlOkail, Samina Hyder Haq Neuroprotective role of

vitamin D in primary neuronal cortical culture. eNeurologicalSci. 17;14:43-48.

doi: 10.1016/j.ensci.2018.12.004. eCollection 2019 Mar. PMID: 30619951

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2019

1. Samina Hyder Haq *, Ghaida Al-Ruwaished1, Moudhi Abdullah Al-

Mutlaq1, Sundus Ali naji1, Maha Al-Mogren1, Sarah Al-Rashed2, Qura tul

Ain , Abir Abdullah Al-Amro& Adnan Al-Mussallam Antioxidant,

Anticancer Activity and phytochemical Analysis of Green Algae,

Chaetomorpha collected from the Arabian Gulf. Sci Rep. 2019 Dec

11;9(1):18906. doi: 10.1038/s41598-019-55309-1.PMID:31827196

2. Abir Abdullah Al-Amro, Moudhi Abdullah Al-Mutlaq, Sara Al-

Moauther, Nouf Al-Tukhaifi, 1Rawan Bin Othaimeen, 1Nada Al-Mutairi,

2Sarah Al-Rashed, 1Fouziah Al-Malki and Samina Hyder Haq

Antioxidant Activity of Rhodophyta Algae Polysiphonia and Laurencia

Collected from the Arabian Gulf.

3. QuraTulAin ,SaminaHyderHaq ,AbeerAl-Modlej2,AbeerAlshammari

,ShahzadAhmed and MuhammadNaeemAnjum, Dose- dependent

cytotoxicity of polyethylene glycol loaded graphene oxide in cultured

cerebral cortical cells. Materials Research Express 6 (10), 105405

4. Qura Tul Ain, Samina Hyder Haq, Abeer Alshammari, Moudhi Abdullah

Al-Mutlaq and Muhammad Naeem Anjum. The systemic effect of PEG-

nGO-induced oxidative stress in vivo in a rodent model. Beilstein J

Nanotechnol. 2019 Apr 18;10:901-911. doi: 10.3762/bjnano.10.91.

eCollection 2019.PMID:31165017

5. Sarah al Hasina, Sarah Al-Hassinah, Shama Parveen, Ali M. Somily,

Muslim Mohammed AlSaadi, Samina H. Haq Anwar Ahmed. Evolutionary

analysis of the ON1 genotype of subtype a respiratory syncytial virus in

Riyadh during 2008–16. Infect Genet Evol. 2019 Dec 24;79:104153. doi:

10.1016/j.meegid.2019.104153. [Epub ahead of print PMID;31881360

2020

1. Qura Tul Ain1*, Samina Hyder Haq2, -chemical synthetic route for the

preparation of Ag nanoparticles supported on reduced graphene oxide.

Accepted in Material EXPRESS

2. Abir Abdullah Alamro1, Ebtesam Atiah Alsulami1, Moudhi Almutlaq1,

Amani Alghamedi 1, Majed Alokail 1 and Samina Hyder Haq*1

Therapeutic Potential of Vitamin D and curcumin in-vitro model of

Alzheimer’s disease. Accepted in Journal of Central Nervous System

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disease.

3. Ajamaluddin Malik, Ejlal Abdullah, Salman Alamery, Samina hyder

Haq, Mohammed Asif Ahmed, Javed Khan. Structural stability and

solubility of glycated camel lens ζ-crystallin (In communication)

4. Nasser Al-Daghri Abir Alamro; Manal Almalky; Nora Alkeraishan;

Osama Amer; Amani Alghamdi; Abdullah Alnaami; Mohammed

Ghouse Ahmed Ansari; Syed Danish Hussain; Fouziah Al-Malki; Tlili

Barhoumi; Samina Haq The Synergistic Effect of Melatonin and

Vitamin D3 on the Gene Expression of Bcl-2 and Bax in Human Breast

Cancer Cell Line (in Communication)

5. Nasser Al-Daghri Abir Alamro;; Nora Alkeraishan; Manal Almalky

Osama Amer; Amani Alghamdi; Abdullah Alnaami; Mohammed

Ghouse Ahmed Ansari; Syed Danish Hussain; Tlili Barhoumi; Samina

Haq . The effect of Vitamin D3 and Melatonin on the gene expression of

p53 in MCF-7 breast cancer cell line. (in communication)

6. Ebtesam Atiah Alsulami, Samina Hyder Haq, Majed Alokail, Amani

Al Ghamedi The effect of Vitamin D3 on the VDR expression in

induced oxidative stress. (in communication)

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