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CURRICULUM VITAE Donald S. Clem, D.D.S., F.A.C.D.

Business Address: Donald S. Clem, III, D.D.S., Inc.

130 Laguna Rd., Suite B Fullerton, California 92835

Business Telephone: (714) 441-0436

EDUCATION

Loyola University of Chicago Major: Biology 1973-1976 Loyola University School of Dentistry 1976-1980

POST-GRADUATE EDUCATION

Veterans Administration Medical Center North Chicago 1980-1981 General Internship

Great Lakes Naval Regional Medical Center 1980-1981 Externship – Periodontology

University of Texas Health Science Center San Antonio, Texas 1981-1984 Residency – Periodontology

PRIVATE PRACTICE

REGENERATIVE SOLUTIONS- Fullerton, CA Practice ownership October 1984-Present

Practice partnership with Nelson T. Yen, DDS, MS January 2003-Present

PROFESSIONAL ORGANIZATIONS

American Academy of Periodontology California Society of Periodontists Western Society of Periodontology American Dental Association Orange County Dental Society Academy of Osseointegration

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SPECIALTY BOARD Diplomate, American Board of Periodontology

ACADEMIC APPOINTMENTS

Cook County Hospital, Chicago General Practice Residency 1981-1982

University of Texas Dental School Instructor, Periodontology 1981-1984

Loma Linda University School of Dentistry Assistant Professor Current

University of Texas, San Antonio Adjunct Clinical Professor Current

AWARDS AND HONORS

Outstanding Public Service in the Field of Periodontics California Society of Periodontists Fellow, American College of Dentists

Fellow, Pierre Fuchard Academy

Service Award for Contributions to Disabled People Rehabilitation Institute of Southern California 1998 Clinical Research Award American Academy of Periodontology 1999

Special Citation American Academy of Periodontology 1999

Outstanding Contribution to the Specialty of Periodontics California Society of Periodontists 2000

Fellow, International College of Dentists 2003

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Special Citation American Academy of Periodontology 2005 Special Citation American Academy of Periodontology 2007 Special Citation American Academy of Periodontology 2012

Son of Italy Humanitarian Award 2012 Fellow, Academy of Osseointegration 2015 Outstanding Contribution to the Field of Periodontics California Society of Periodontists 2016 R. Earl Robinson Periodontal Regeneration Award American Academy of Periodontology Foundation 2017

COMMUNITY SERVICE Board of Directors and President Rehabilitation Institute of Southern California (Non-profit organization dedicated to service and treatment of the physically disabled)

PROFESSIONAL APPOINTMENTS

Chairman, Legislative Committee California Society of Periodontists 1984-1991

Chairman, Committee on Sedation California Society of Periodontists 1984-1996 Member, California Dental Association Task Force on Conscious Sedation 1988-1990

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Board of Directors Western Society of Periodontology 1994

President California Society of Periodontists 1995 Council on Legislation California Dental Association 1992-1998 Board of Directors Delta Dental of California 1999-2004

Committee on Anesthesia American Dental Association 2002-2005 Board of Trustees, American Academy of Periodontology 2000-2006 ACADEMY OF OSSEOINTEGRATION

Subcommittee Task Force on Expanding Implant Utilization Academy of Osseointegration 2001 - 2002

2010 Annual Meeting Committee

Academy of Osseointegration 2008 – 2010 Nominating Committee Academy of Osseointegration 2011 – 2013 2014 Annual Meeting Committee Academy of Osseointegration 2012 – 2014 Finance & Audit Committee Academy of Osseointegration 2013 – 2014 Chair, 2015 Annual Meeting Committee Academy of Osseointegration 2013 – 2015

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AMERICAN ACADEMY OF PERIODONTOLOGY APPOINTMENTS Chairman, Interactive Clinics American Academy of Periodontology 1991 Annual Meeting Program Subcommittee American Academy of Periodontology 9/1993-10/1996 Chairman, Annual Meeting General Session American Academy of Periodontology 1995 Chairman, Committee on 1997 Regeneration Conference American Academy of Periodontology 9/1995-10/1997

Chairman, General Sessions

American Academy of Periodontology 9/1994-10/1996

Public Communication Committee

American Academy of Periodontology 9/1995-10/1996

Nominating Committee American Academy of Periodontology

1996-1997 Chairman, Public Communication Committee

American Academy of Periodontology 10/1996-9/1997 Chairman, Public & Professional Communication Committee

American Academy of Periodontology 10/1997-9/1999

Chairman, Regeneration Conference American Academy of Periodontology 1997

Spokesperson American Academy of Periodontology 1997-Present Director, Board of Directors American Academy of Periodontology Foundation 10/1997-9/1998

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Secretary/Treasurer, Board of Directors American Academy of Periodontology Foundation 9/1998-9/2000 Editorial Board Journal of Periodontology 1998-2001

Board Liaison, Public & Professional Communications American Academy of Periodontology

10/1999-9/2000 Chairman, Public and Professional Communications Committee American Academy of Periodontology 1998-2000

Trustee, Board of Trustees American Academy of Periodontology 9/2000-9/2006

President, Board of Directors American Academy of Periodontology Foundation 9/2000-10/2003

Task Force on Visioning Process American Academy of Periodontology 10/2001-9/2002

Board Liaison, Education Committee American Academy of Periodontology 10/2001-9/2002

Member, Editor’s Contract Review Committee American Academy of Periodontology 9/2002-9/2003 Executive Director Review Committee American Academy of Periodontology 9/2002-9/2003 President American Academy of Periodontology Foundation 1/2003

Director, Board of Directors American Academy of Periodontology Foundation 9/2003-9/2005

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Nominating Committee American Academy of Periodontology 9/2003-11/2004

Finance Committee American Academy of Periodontology 9/2003-11/2004

Member, AAP/AAPF Joint Task Force on an Education Endowment Fund 7/2004-3/2005 Member, Strategic Planning Committee 11/2004-9/2005 Executive Committee American Academy of Periodontology Foundation 11/2004-9/2005

Executive Director Review Committee American Academy of Periodontology Foundation 11/2004-9/2005

Planning Committee American Academy of Periodontology Foundation 2004-2005

Chairman, Task Force on Referral Guidelines American Academy of Periodontology Foundation 12/2004-9/2006 Member, Task Force to Meet with the Editor American Academy of Periodontology Foundation 9/2005-9/2006 Member, Strategic Planning Committee 5/2006-9/2006

Nominating Committee American Academy of Periodontology

9/2005-9/2006 Officer Member, Finance Committee American Academy of Periodontology 10/2006-10/2007

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Officer Candidate, Board of Trustees American Academy of Periodontology 10/2006-10/2007 Chairman, Finance Committee American Academy of Periodontology 10/2007-9/2008 Consultant, Task Force to Review Guidelines American Academy of Periodontology Foundation 10/2007-9/2008

Secretary/Treasurer, Editorial Liaison Committee American Academy of Periodontology 10/2007-9/2008

Secretary/Treasurer, Strategic Planning Committee American Academy of Periodontology 10/2007-9/2008 Secretary/Treasurer, Executive Committee American Academy of Periodontology 10/2007-9/2008 Secretary/Treasurer, Board of Trustees American Academy of Periodontology 10/2007-9/2008 Member, Task Force to Investigate the International Journal of Periodontics American Academy of Periodontology 11/2008-9/2009 Vice President, Finance Committee American Academy of Periodontology 9/2008-9/2009 Vice President, ADA Liaison Committee American Academy of Periodontology 9/2008-9/2009 Vice President, Strategic Planning Committee American Academy of Periodontology 9/2008-9/2009 Vice President, Editorial Liaison Committee American Academy of Periodontology 9/2008-9/2009

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Vice President, Executive Committee American Academy of Periodontology 9/2008-9/2009 Vice President, Board of Trustees American Academy of Periodontology 9/2008-9/2009 President-Elect, Finance Committee American Academy of Periodontology 9/2009-11/2010

President-Elect, Strategic Planning Committee American Academy of Periodontology 9/2009-11/2010 President-Elect, Executive Committee American Academy of Periodontology 9/2009-9/2010

Member, Steering Committee on Inflammation American Academy of Periodontology 9/2009-11/2010 President-Elect, Editorial Liaison Committee American Academy of Periodontology 9/2009-11/2010 President-Elect, Board of Trustees American Academy of Periodontology 9/2009-11/2010 President-Elect, ADA Liaison Committee American Academy of Periodontology 9/2009-11/2010 President-Elect, Continuing Education Oversight Committee American Academy of Periodontology 9/2009-11/2010 Member, AAP/AGD Task Force on Collaborative Projects 9/2009-11/2010 Director, Board of Directors American Academy of Periodontology Foundation 9/2009-10/2012

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Member, AAP/AAPF Task Force to Examine AAPF Strategic Objectives 11/2009-10/2012 President, Executive Committee American Academy of Periodontology 11/2010-11/2011 Chairman, Task Force on Employee Benefits American Academy of Periodontology 5/2011-9/2012

President, Editorial Liaison Committee American Academy of Periodontology 11/2010-11/2011 Chairman, Editorial Liaison Committee American Academy of Periodontology 11/2010-11/2011 President, ADA Liaison Committee American Academy of Periodontology 11/2010-11/2011 President, Board of Directors American Academy of Periodontology 11/2010-11/2011 Past President, Executive Committee American Academy of Periodontology 11/2011-10/2012 Member, Task Force on Revised Accreditation Standards American Academy of Periodontology Foundation 8/2011-10/2012 Past President, Executive Director Search Committee American Academy of Periodontology 11/2011-10/2012 Past President, Board of Directors American Academy of Periodontology 11/2011-10/2012 LOYOLA UNIVERSITY OF CHICAGO Council of Regents 2015 - Present

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PRESENTATIONS

“Living with Oral Cancer” Loyola University Dental School 1980 “Review of Early Diagnosis of Oral Neoplasms” North Chicago V. A. Medical Center 1981 “Manifestations of Oral Desquamative Lesions” Cook County Hospital 1981 “Use of Citric Acid in Regeneration of New Attachment” University of Texas Dental School 1982

“Desquamative Gingivitis” University of Texas Dental School 1982

“Periodontic - Restorative Relationships” University of Texas 1983

“Current Status of Dental Implants” Loma Linda University Dental School 1984

“Osseointegrated Implants” Fullerton, California 1985

“Crown Lengthening Procedures” Dental Study Group Anaheim, California 1985

“Ridge Augmentation Procedures” Dental Study Group Anaheim, California 1985

“Periodontal Surgical Reconstruction” Dental Study Group Yorba Linda, California 1986

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“Current and Future Concepts of Periodontics” Orange County Dental Academy Orange, California 1988 “Stent Design for Implant Placement” North Orange County Implant Group Fullerton, California 1990 “Periodontic - Restorative Relationships in Osseointegrated Implants” North Orange County Implant Group Fullerton, California 1991

“Regeneration of Deficient Alveolar Ridges with Implants and Guided Tissue Regeneration” North Orange County Implant Group Fullerton, California 1991

“Single Stage Implants” American Academy of Periodontology New York, New York 1995

“Preparing for Oral Diplomate Examination” American Academy of Periodontology New York, New York 1995

“Regeneration of Bone around Implants” Orange County Dental Academy Anaheim, California 1996

“Implant Site Development-Surgical Considerations” Nobel Biocare Las Vegas, Nevada 1996

“Surgical Aspects of Regeneration” Beverly Hills Dental Academy Beverly Hills, California 1997

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“Single Tooth Posterior Implants” ITI International Symposium Boston, Massachusetts 1998

“Update on Periodontal Non-Surgical Alternatives” North Orange County Study Group Fullerton, California 1998 “Implant Site Development” Orange County Dental Academy Anaheim, California 1998 “Periodontal Medicaments” Orange County Hygiene Study Group Fullerton, California 1998

“Update on Emdogain” Biora, Inc. Chicago, Illinois 1999

“Clinical Perspectives on Enamel Matrix Proteins” American Academy of Periodontology Honolulu, Hawaii 2000

“Roundtable Treatment Planning” American Academy of Periodontology Philadelphia, Pennsylvania 2001

“Update on Enamel Matrix Proteins” Northeast Society of Periodontists New York, New York 2002

“The Periodontist’s Role in Treating the Failing Dentition” American Academy of Periodontology New Orleans, Louisiana 2002

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“Periodontal Regeneration” American Academy of Periodontology Chicago, Illinois 2003 “Oral Plastic Surgery” University of New York at Stony Brook New York, New York 2003

“Clinical Perspectives on Enamel Matrix Proteins” Capital Perio Group Sacramento, California 2004

“Maxillary Anterior Implants” North Orange County Implant Group Fullerton, California 2004

“Periodontal Regeneration” North Orange County Hygiene Study Group Fullerton, California 2005

“Oral Plastic Surgery in the 20/20 Vision” Southwestern Society of Periodontists Dallas, Texas 2/2005

“Subantral Bone Augmentation” Southern California Implant Group Fullerton, California 5/2005

“Sinus Grafting” ITI World Symposium Munich, Germany 6/2005 “Periodontal Regeneration” Northeast Society of Periodontists New York, New York 4/2006

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“Current Concepts in Periodontal Therapy” North Orange County Hygiene Study Group Fullerton, California 6/2006

“Regeneration” American Academy of Esthetic Dentistry Grand Cayman Islands 8/2006

“Managing Implant Complications in the Esthetic Zone” Straumann World Symposium New York, New York 6/2007

“Local Delivery Antimicrobials” American Academy of Periodontology Boston, Massachusetts 10/2008 “Hard Tissue Failures” Academy of Osseointegration San Diego, California 3/2009 “A Clinician’s Perspective of Periodontal Regeneration” Northeast Society of Periodontists New York, New York 4/2009 “Guided Bone Regeneration” American Academy of Periodontology San Diego, California 9/2009 “AAP President: Keynote Address” AAP Spring Conference 2011 Chicago, Illinois 4/2011

“Oral Lesions” Orange County Dental Hygiene Society Costa Mesa, California 6/2011

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“Current and Future Scope of Periodontology” Louisiana Society of Periodontists New Orleans, Louisiana 7/2011 “The Team Approach to Periodontal Therapy” The 59th Annual Scientific Session, Bellagio Resort & Casino Las Vegas, Nevada 9/2011

Guest Speaker, World Health Organization (WHO) Geneva, Switzerland 6/2011 “Team Approach of Managing Implant Complications in the Esthetic Zone” Spring Conference 2012 American Academy of Periodontology Chicago, Illinois 4/2012 “Comprehensive Periodontal Therapy and the Team Approach” ADHA Annual Meeting Phoenix, Arizona 6/2012 “Critical Decision Making in Periodontics” Bunting Memorial Lecture Detroit, Michigan 12/2012 “Keynote Address AAP-AAO Collaborative Conference Palm Springs, California 2/2013 “When to Place Grafts and When to Place Implants” Academy of Osseointegration Tampa, Florida 3/2013

“Comprehensive Periodontal Therapy” NOCHG Fullerton, California 3/2013

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“Regeneration: A Clinician’s Perspective” Straumann Corporate Forum Chicago, Illinois 4/2013 “Esthetic Determinants for Success” ITI Congress Chicago, Illinois 4/2013 “The Team-Approach to Comprehensive Periodontal Therapy” Dr. Peter Fedi Memorial Lecture Kansas City, Missouri 4/2013 “Soft Tissue Enhancements for Teeth and Dental Implants” North Orange County Implant Group Fullerton, California 4/2013 “Update on Periodontal Therapy” Orange County Dental Academy Irvine, California 5/2013 Opening General Session American Academy of Periodontology 100th Anniversary San Francisco, CA 2014 “Regeneration and the Dental Hygienist” Straumann San Francisco, CA 2014 “Guided Bone Regeneration” Orapharma San Francisco, CA 2014 “The Team Approach to Managing Implant Complications” Northeast Society of Periodontists 2014

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“Implant Site Development” Nobel Biocare Cincinnati, OH 2014 “Contemporary Periodontal Therapy”

Nabors Visiting Professorship Endowed Lecture 11/2014 “A Team Approach to Comprehensive Periodontal Therapy” Periodontal Health Associates Study Group 1/2015

“Our Patients Today and Tomorrow” American Academy of Periodontology Spring Conference 5/2015 Keynote Address Western Society of Periodontology Annual Meeting 2015 “The Team Approach to Implant Complications” Straumann Distinguished Lecture Temple University 2015 “Update on Peri-Implant Diseases” Morita Corporate Forum American Academy of Periodontology 2015 “Guided Bone Regeneration” Loma Linda University 2015 “Peri-Implant Diseases” American Academy of Periodontology Orlando, FL 3/2016 “Peri-Implant Diseases” University of Southern California Periodontal-Implant Symposium 2016

“Peri-Implant Diseases” California Society of Periodontists Annual Meeting Santa Barbara, CA 5/2016

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“Growth Factors and Regeneration” American Academy of Cosmetic Dentistry Anaheim, CA 6/2016 “Regeneration around Teeth and Implants” International Symposium of Periodontics and Restorative Dentistry Boston, MA 6/2016 “A Periodontist’s Perspective on Bone Reduction in All-On-4 Cases” Nobel Biocare Global Symposium New York, NY 6/2016 “Use of Lasers for Surgical Management of Peri-Implantitis Lesions” American Academy of Periodontology Annual Meeting San Diego, CA 9/2017 ”Team Approach to Managing Periodontal and Peri-Implant Diseases” Walsh Study Group La Grange, IL 1/2017 “Team- Approach to Managing Implant Complications” Nobel Biocare Facility Yorba Linda, CA 3/2017 “Referral Based Dental Implant Practice” Academy of Osseointegration Annual Meeting Orlando, FL 3/2017

PUBLICATIONS

Conscious Sedation, Clinical and Legislative Review Clem, D.S., Seult, R., Journal, California Dental Association, 6/1988 Guided Tissue Regeneration in Periodontology and Implantology Clem, D.S., Bishop, J.P., Journal, California Dental Association, 12/1991

Gestuerte Geweberegeneration in Parodontologie und Implantologie Clem, D.S., Bishop, J.P., Phillip Journal, 3/1993

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A Multicenter Retrospective Analysis of the ITI Implant System Used for Single-Tooth Replacements: Preliminary Results at 6 or More Months of Loading Levine, R.A., Clem, D.S., Wilson, T.G., Higginbottom, F., Saunders, S.L., Journal, Int J Oral Maxillofac Implants, 1997

Implants in Regenerated Bone: Long-Term Survival Nevins, M., Mellonig, J.T., Clem, D.S., Reiser, G.M., Buser, D.A., Journal, Int J Periodontics and Restorative Dentistry, Vol. 18, No. 1, 1998 Multicenter Retrospective Analysis of the ITI Implant System Used for Single-Tooth Replacements: Results of Loading for 2 or More Years Levine, R.A., Clem, D.S., Wilson, T.G., Higginbottom, F., Solnit, G., Journal, Int J Oral Maxillofac Implants, 1999; 14:516-520 Implant Site Development Using Guided Bone Regeneration Techniques Clem, D.S., Journal, Compendium of Continuing Education in Dentistry, May, 2000; Vol. 21, No. 5: 424-430

Multicenter Retrospective Analysis of the Solid-Screw ITI for Posterior Single-Tooth Replacements Levine, R.A., Clem, D.S., Beagle, J., Ganeles, J., Johnson, P., Solnit, G., Keller, G.W., Journal, Int J Oral Maxillofac Implants, 2002; Vol. 17, No. 4: 550-556

Histologic Evaluation of Mineralized and Demineralized Freeze-Dried Bone Allograft for Ridge and Sinus Augmentations Cammack, II, G.V., Nevins, M., Clem, D.S., Hatch, J.P., Mellonig, J.T., Journal, Int J Periodontics and Restorative Dentistry, Vol. 25, No. 3, 2005 Clinical Histologic, and Histomorphometric Evaluation of Mineralized Solvent-dehydrated Bone Allograft (Puros) in Human Maxillary Sinus Grafts Noumbissi, S.S., Lozada, J.L., Boyne, P.J., Rohrer, M.D., Clem, D.S., Kim, J.S., Journal of Oral Implantology: Vol. 31, No. 4, 171-179, 2/2005

Guidelines for the Management of Patients with Periodontal Disease Krebs, K.A., Clem, D.S.; American Academy of Periodontology. J. Periodontology; 77(9):1607-11, 9/2006 The “Innovator’s Dilemma” for Periodontists Kornman, K.S., Clem, D.S. J. Periodontology; Vol. 81, No. 5, 646-649, 5/2010 Dental Implant Complications – Etiology, Prevention, and Treatment Clem, D.S., Contributing Author 450-454, Wiley-Blackwell Publishing 2010

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The Crucial Role of the Dental Hygienist in Periodontal Care Donald S. Clem, DDS Dimensions of Dental Hygiene, 11/2010 The Team Approach – How the partnership between general dentists, dental hygienists, and periodontists can help improve our provision of care and, ultimately, patient outcomes. Donald S. Clem, DDS Dimensions of Dental Hygiene, 11/2010 Looking Ahead with New AAP President Dr. Donald S. Clem AAP Periospectives; 10/2010 – 12/2010 AAP President’s Address Donald S. Clem, DDS J. Periodontology; Vol. 83, No. 2, Pages 135-138, 2/2012

Navigating the Clinical Road Map Donald S. Clem, DDS Dimensions of Dental Hygiene, 11/2011 The Power of Access Donald S. Clem, DDS Clinical Advances in Periodontics; Vol. 1, No. 2, 77-77, 8/2011

The Team Approach to Replacing the Congenitally Missing Lateral Incisor: Restorative and Periodontal Considerations Donald S. Clem, DDS and Kenneth F. Hinds, DDS Clinical Advances in Periodontics Vol. 3, No. 2, May 2013

A Practice-Based Case Series Evaluation of a Porcine Collagen Matrix to Augment Keratinized Tissue and Increase Soft Tissue around Existing Dental Implants Schallhorn, R.A., Charles, A., Clem, D., McClain, P.K., Newman, M.G. International J. Perio Rest Dent 2015; 35: 99-103 Unsolved Mysteries: Understanding Patients and Periodontal Disease in the Face of New Realities and Findings Clem, D.S., Kornman, K.S., Journal, Compendium of Continuing Education in Dentistry, November, 2015; Vol. 36, No. 4: 14-21 Dental Implant Complications- 2nd edition Clem, DS. Contributing Author, Wiley-Blackwell Publishing 2015 Periodontal Regeneration- Intrabony Defects: A Consensus Report from the AAP Regeneration Workshop Mark A. Reynolds, Richard T. Kao, Paulo M. Camargo, Jack G. Caton, Donald S. Clem, Joseph P. Fiorellini, Maria L. Geisinger, Michael P. Mills, Salvador Nares, and Marc L. Nevins, J.Perio 2015; 86: 105-107 (suppl.)

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A Randomized Clinical Trial Evaluating rh-FGF-2/-TCP in Periodontal Defects D.L. Cochran, T.-J. Oh, M.P. Mills, D.S. Clem, P.K. McClain, R.A. Schallhorn, M.K. McGuire, E.T. Scheyer, W.V. Giannobile, M.S. Reddy, R.V. Abou-Arraj, P.J. Vassilopoulos, R.J. Genco, N.C. Geurs, and A. Takemura, J. of Dental Research 2016; 95(5): 523-530

VIDEO INTERVIEW

California Dental Association video interview with the American Academy of Periodontology: Link between periodontal diseases and cardiovascular diseases Dentalproductsreport.com; 5/4/2012

WRITTEN INTERVIEW

Leaders in Dentistry: A conversation with Dr. Donald Clem By Rabia Mughal, Contributing Editor Leaders in Dentistry; 8/17/11

CLINICAL RESEARCH EXPERIENCE

Investigator for Prospective Randomly Controlled Clinical Trial on Efficiency of Metronidazole Gel; 1989

Investigator for Retrospective Analysis of Implant Function in Regenerated Bone; 1996

Investigator for Histologic Evaluation of Mineralized and Demineralized Freeze-Dried Bone Allograft for Ridge and Sinus Augmentations; 2005

Investigator for a Porcine Collagen Matrix to Thicken Soft Tissue, Increase Keratinized Tissue and Improve Esthetics Around Existing Dental Implants: 2011

Investigator for Clinical Trial to Evaluate the Safety and Effectiveness of GUIDOR® Growth Factor Enhanced Bone Graft Substitute for the Treatment of Periodontal Defects 6-months Post-Surgery; 2014

Investigator for Clinical Trial to Evaluate Colgate PerioPatch in Periodontal Practices; 2014

HOBBIES AND INTERESTS Architecture, fishing, kayaking, running